• Journal of Trauma and Injury
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• v.35 no.2
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• pp.71-75
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• 2022

Trauma care is evolving throughout the world to meet the demand resulting from rapidly increasing rates of mortality and morbidity related to external injuries. The State Major Trauma Service was designated to Royal Perth Hospital in 2004 to provide comprehensive care for trauma patients in Western Australia (WA), which is the largest state by area in the country. The State Major Trauma Unit, which was established in 2008, functions as a level I center and admits over 1,000 major trauma patients per year, making it the second busiest trauma center in Australia. The importance of recording data related to trauma was identified by the trauma service in WA to inspire higher standards of patient care and injury prevention. In 1994, the service established a trauma registry, which has undergone significant changes over the last two decades. The current State Trauma Registry is linked to a statewide database called the Data Linkage System. The linked data are available for policy development, quality assurance, and research. This article discusses the evolution of the trauma service and the registry database in the WA health system. The State Trauma Registry has enormous potential to contribute to research and quality improvement studies along with its ability to link with other databases.

• Korean Journal of Animal Reproduction
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• v.26 no.3
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• pp.299-308
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• 2002

In horse, a single gene encodes both eCG and eLH $\beta$ subunits. The difference between eCG and eLH lies in the structure of their glycoresidues, which are both sialylated and sulfated in LH and sialylated in CG eCG consists of highly glycosyiated $\alpha$- and $\beta$-subunits and is an unique member of the gonadotropin family because it elicits response characteristics of both FSH and LH in other species than the horse. This dual activity of eCG in heterologous species is of fundamental interest to the study of gonadotropin structure-function relationships and the understanding of the molecular bases of the specific interactions of these hormones with their receptors. Thus, eCG is a dintinct molecule from the view points of its biological function and glycoresidue structures. The oligosaccharide at Asn 56 of the $\alpha$-subunit plays an indispensable role, whereas the carboxyl-terminal extension of the eCG $\beta$-subunit with its associated O-linked oligosaccharides is not improtant for, the in vitro LH-like activity of eCG. In contrast, both N- and O-linked oligosaccharides play important roles for FSH-like activity and increase FSH-like activity by removal of N- and O-linked oligosaccharides. Therefore, the dual LH- and FSH-like activities of eCG can be clearly separated by removal of either the N-linked oligosaccharide on the $\alpha$-subunit or CTP-associated O-linked oligosaccharides from its $\beta$-subunit. The glycoresidues seem to play crucial roles fer biological activities. The tethered-eCG was effciently secreted and showed similar LH-like activity to the dimeric eCG $\alpha$/ $\beta$ and native eCG. FSH-like activity of the tethered-eCG was also shown similarly in comparison with the native and wild type eCG $\alpha$/ $\beta$. Our data for the first time suggest that the tethered-eCG can be expressed efficiently and the produced product by the CHO-Kl cells is fully LH- and FSH-like activities in rat in vitro bioassay system. Our results also suggest that this molecular can imply particular models ot FSH-like activity not LH-like activity in the eCG. Taken together, these data indicate that the constructs of tethered molecule will be useful in the study of mutants that affect subunit association and/or secretion.

• Journal of Korea Multimedia Society
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• v.9 no.11
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• pp.1421-1434
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• 2006

Spatial data warehouses provide analytical information for decision supports using SOLAP (Spatial On-Line Analytical Processing) operations. Many researches have been studied to reduce analysis cost of SOLAP operations using pre-aggregation methods. These methods use the index composed of fixed size nodes for supporting the concept hierarchy. Therefore, these methods have many unused entries in sparse data area. Also, it is impossible to support the concept hierarchy in dense data area. In this paper, we propose a dynamic pre-aggregation index method based on the spatial hierarchy. The proposed method uses the level of the index for supporting the concept hierarchy. In sparse data area, if sibling nodes have a few used entries, those entries are integrated in a node and the parent entries share the node. In dense data area, if a node has many objects, the node is connected with linked list of several nodes and data is stored in linked nodes. Therefore, the proposed method saves the space of unused entries by integrating nodes. Moreover it can support the concept hierarchy because a node is not divided by linked nodes. Experimental result shows that the proposed method saves both space and aggregation search cost with the similar building cost of other methods.

• Journal of Global Scholars of Marketing Science
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• v.14
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• pp.1-16
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• 2004

This paper explores the impact of banner exposure and clicking on brand-attitude changes and purchase intention changes. It is found that simple exposure to banner ads does not change people's initial brand-attitude and purchase intention, while voluntary exposure to target ads by clicking banner ads results in positive or negative brand attitude and purchase intention changes depending on the likability of the linked target ads from the banner ads. For methodology, this study employed a pretest posttest control group design and used online data collection technology called Cold Fusion. A total of 961 subjects participated in this research.

• Communications for Statistical Applications and Methods
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• v.27 no.1
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• pp.79-95
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• 2020

The globalization of financial markets has broadened investment opportunities. International investors' investment portfolios consist of financial instruments from various countries; consequently, the risks associated with economic dependence among countries should be carefully considered. Step-down equity-linked securities (ELS) are a structured financial product that have recently become popular among Korean investors. Payoffs are based on two or three stock indices from different regions; therefore, dependence between the indices should be reflected in the risk analysis. In this study, we consider a regime-switching copula model to describe the joint behavior of two stock indices- the Eurostoxx50 and the Hang Seng China Enterprises Index (HSCEI). These indices are commonly used as underlying assets of step-down ELS. Using historical data, we analyze the risk associated with step-down ELS through the probabilities of early redemption. A regime-switching copula model can accommodate complicated dependence. Thus, it should be considered in the risk analysis of step-down ELS.

• Journal of Pharmaceutical Investigation
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• v.41 no.2
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• pp.111-115
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• 2011

pH-sensitive cross-linked polymeric micelles were synthesized by using block ionomer complexes of poly(ethylene oxide)-b-poly(methacrylic acid) (PEO-b-PMA) with calcium ions as micellar templates. An anticancer drug, doxorubicin (DOX) was conjugated on the cross-linked ionic cores of micelles via acid-labile hydrozone bonds. The resulting DOX-conjugated, pH-sensitive micelles are stable at physiological conditions, whereas the release of DOX was significantly increased at the acidic pH. Such micelles were internalized to lysosomes, and acidic pH in lysosomes triggers the release of DOX upon internalization in MCF-7 breast cancer cells. The released DOX entered the cell nucleus and eventually killed cancer cells. Therefore, these data demonstrate that the pH-sensitive micelles could be a promising nanocarrier for delivery of anticancer drug, DOX.

• Research in Community and Public Health Nursing
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• v.27 no.2
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• pp.132-143
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• 2016

Purpose: The purpose of this study was to investigate the effects of sexual abuse prevention education program linked to elementary physical and psychological development on sexual knowledge and attitude. Methods: The participants were the elementary school students of fifth and sixth grades in S city, South Korea (experimental, comparison, and control group=96, 96, and 74, respectively). The experimental group received sexual abuse prevention education linked physical and psychological development, 6 sessions (3 sessions are physical and psychological development educations and 3 other sessions are sexual abuse prevention educations). The comparison group received sexual abuse prevention educations, 3 sessions (the same curriculum of the experimental group). The control group didn't receive any sexual education. The data were analyzed by $x^2$ test and t-test, and ANOVA using the SPSS program. Results: The experimental group showed significantly better sexual knowledge and attitude than the comparison and control group. Conclusion: Sexual abuse prevention education program linked physical and psychological development is required for elementary school students, to improve the sexual knowledge and attitude.

• Child Health Nursing Research
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• v.25 no.2
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• pp.165-174
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• 2019

Purpose: This study investigated differences in the relationships of factors including emotional problems, self-perception, parental behavior, and peer attachment with smartphone dependency (SD) among middle school, high school, and college students in South Korea. Methods: This study used data from a nationwide sample of 1,882 middle school, 1,821 high school, and 1,346 college students who owned smartphones. Descriptive statistics and multiple regression analysis were conducted to investigate the predictors of SD based on school level. Results: SD scores significantly differed across school levels. Female gender, more aggressive behavior, less ego-identity, and less monitoring parental behavior were linked to higher SD at all school levels. Less self-esteem and intrusive parental behavior were linked to SD in middle school students. In high school students, additional factors related to higher levels of SD were resilience, intrusive / inconsistent parental behavior, peer trust and alienation, and depression. Additionally, resilience, over-expectant parental behavior, and peer trust were linked to higher SD in college students. Conclusion: This study provides insights into SD and predictors of SD among middle school, high school, and college students. Based on these findings, SD prevention programs should be developed according to the developmental stages of adolescents and young adults.

• Journal of the Korean Association of Geographic Information Studies
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• v.9 no.4
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• pp.60-70
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• 2006

National atlas map for provide various information is one part of National territorial Statatics Survey but National atlas map in 2004 year don't have stability and ability. National territorial Statatics Survey in 2005 years have octuple data compare with data in 2004 years but have only one map. One map is going to provide with stability and ability. We don't use DBMS, But We make a similarly struct in file based program. We programmed system of dynamic-linked data with spatial data. To dynamic-linked system, we make search engine to based index struct and make combobox search system. spatial data only have index codes(year, national terrial indicator, area). If spatial data request specfied data, search engine search index code and provide DB data. New system is middle step of using DBMS. We redraw map for display real Korea area (with dokdo). New map is shape and similar Korea map.

• Journal of Preventive Medicine and Public Health
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• v.55 no.3
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• pp.253-262
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• 2022

We aimed to review the current data composition of the Korean Tuberculosis and Post-Tuberculosis Cohort, which was constructed by linking the Korean Tuberculosis Surveillance System (KNTSS; established and operated by the Korean Disease Control and Prevention Agency since 2000) and the National Health Information Database (NHID; established by the National Health Insurance Service in 2012). The following data were linked: KNTSS data pertaining to patients diagnosed with tuberculosis between 2011 and 2018, NHID data of patients with a history of tuberculosis and related diseases between 2006 and 2018, and data (obtained from the Statistics Korea database) on causes of death. Data from 300 117 tuberculosis patients (177 206 men and 122 911 women) were linked. The rate of treatment success for new cases was highest in 2015 (86.7%), with a gradual decrease thereafter. The treatment success rate for previously treated cases showed an increasing trend until 2014 (79.0%) and decreased thereafter. In total, 53 906 deaths were confirmed among tuberculosis patients included in the cohort. The Korean Tuberculosis and Post-Tuberculosis Cohort can be used to analyze different measurement variables in an integrated manner depending on the data source. Therefore, these cohort data can be used in future epidemiological studies and research on policy-effect analysis, treatment outcome analysis, and health-related behaviors such as treatment discontinuation.