• Title/Summary/Keyword: Linkage group analysis

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A Study Of EIS Build Method by ISP Base for Large Scale Enterprise Associate Company (대기업 협력 업체를 위한 ISP 기반의 EIS 구축 방법에 관한 연구)

  • Kim, Soo-Kyum;Ha, Soo-Cheol
    • Journal of the Korea Society of Computer and Information
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    • v.15 no.1
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    • pp.159-166
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    • 2010
  • It is noteworthy that EIS Consulting Method by ISP based on ERP Linkage Type for Large Scale Enterprise Associate Company. In this thesis, IT Strategy plan and methodology are suggested in order to solve the several problems including standardization on implementation of EIS Introduction and operation between large-small enterprise. Integration of business and information technical is made by Business management group's continuous IT concern and future information strategy. Also this paper proposes ISP Planning method (environment analysis, present analysis, IT analysis, target IT plan etc..), EIS Construction (based ERP Real data/time). In addition to, we suggest to use electron industry model and LCD/LED field in this system.

Association Analysis of Monocyte Chemotactic Protein-3 (MCP3) Polymorphisms with Asthmatic Phenotypes

  • Park, Byung-Lae;Kim, Lyoung-Hyo;Choi, Yoo-Hyun;Cheong, Hyun-Sub;Park, Hae-Sim;Hong, Soo-Jong;Choi, Byoung-Whui;Lee, June-Hyuk;Uh, Soo-Taek;Park, Choon-Sik;Shin, Hyoung-Doo
    • BMB Reports
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    • v.38 no.1
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    • pp.77-81
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    • 2005
  • The monocyte chemotactic protein-3 (MCP3), on chromosome 17q11.2-q12, is a secreted chemokine, which attracts macrophages during inflammation and metastasis. In an effort to discover additional polymorphism(s) in genes whose variant(s) have been implicated in asthma, we scrutinized the genetic polymorphisms in MCP3 to evaluate it as a potential candidate gene for asthma host genetic study. By direct DNA sequencing in twenty-four individuals, we identified four sequence variants within the 3 kb full genome including 1,000bp promoter region of MCP3; one in promoter region (-420T>C), three in intron (+136C>G, +563C>T, +984G>A) respectively. The frequencies of those four SNPs were 0.020 (-420T>C), 0.038 (+136C>G), 0.080 (+563C>T), 0.035 (+984G>A), respectively, in Korean population (n = 598). Haplotypes, their frequencies and linkage disequilibrium coefficients (|D'|) between SNP pairs were estimated. The associations with the risk of asthma, skin-test reactivity and total serum IgE levels were analyzed. Using statistical analyses for association of MCP3 polymorphisms with asthma development and asthma-related phenotypes, no significant signals were detected. In conclusion, we identified four genetic polymorphisms in the important MCP3 gene, but no significant associations of MCP3 variants with asthma phenotypes were detected. MCP3 variation/haplotype information identified in this study will provide valuable information for future association studies of other allergic diseases.

Identification of Quantitative Trait Loci for Resistance to Soybean Cyst Nematode Race 5 (콩 Cyst 선충 Race 5에 대한 저항성 QTL 탐색)

  • Choi, In-Soo;Kim, Yong-Chul;Kim, Sung-Man;Lee, Chung-Yeol;Park, Hyean-Cheal;Halina T. Skorupska
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.42 no.6
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    • pp.712-721
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    • 1997
  • The objectives of this study were; (1) to identify and localize QTLs for resistance to soybean cyst nematode(SCN) race 5 on RAPD map, (2) to idntify the magnitude and mode of inheritance for each QTL, and (3) to identify the best combinations of QTLs for resistance to SCN race 5. Based on the univariate regression analysis, we detected 26 markers(22 RAPD and 4 RFLP) which showed significant association(P<0.05) with resistance to SCN race 5. From MAPMAKER /QTL analysis, we identified two regions (LGC-20 and Group 2) for resistance to SCN race 5. The QTL that was localized at 8.0 cM from pK418C on LGC-20 showed a recessive mode of inheritance and the QTL that was localized between W03 and E02$^3$ on Group 2 showed a dominant mode of inheritance. Two pairs of flanking markers (E02$^3$ and W03, pK418C and pK418E$_1$) and one unlinked RAPD marker, G10$^1$ were used for multiple regression analysis. Marker combination which was composed of 4 markers, E02$^3$, G10$^1$, W03, and pK418E$_1$, explained the highest amount of phenotypic variation by SCN (35.2%). Further research for the identification of QTLs for resistance to SCN race 5 to explain larger portion of phenotypic variation is needed.

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A Study of Development and Implementation of Problem-based Learning Program in Communication Curriculum of Nursing Education (문제중심 학습방법을 적용한 의사소통론 교과목 개발 및 적용)

  • Hyun, Myung-Sun;Kang, In-Ae;Kong, Seong-Sook
    • The Journal of Korean Academic Society of Nursing Education
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    • v.9 no.1
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    • pp.144-154
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    • 2003
  • Recently, in the academic disciplines critical thinking has been emphasized as the new evolution in education. Problem-based learning is suggested as the evolutionary learning method in developing critical thinking. In the nursing education, PBL is offered as an appropriate teaching method to prepare nurse student for professional. PBL is a student-centered learning strategy aimed at developing critical thinking, motivating self-directed study and attaining autonomy. The purpose of this study was to develop the communication curriculum of nursing education based on PBL and implementing of it. PBL module was developed focused on five communication situations. And learning strategies to facilitate the learning process and the guided questions to stimulate student inquiry were also developed. This PBL education was conducted for six students in the master's course during the 14 weeks from March, 2000 to June, 2000. The outcomes of the PBL education were examined based on the content analysis of the students reflective journal. As a result, it was found that students experienced the effect of it focused on self-oriented, group-oriented, and practice-oriented domain. In the self-oriented domain, the findings indicate that there were 5 kinds of concepts including 'motivation for self-directed study', 'transition toward certainty in knowledge acquisition', 'attempt to apply their prior knowledge into new situation', 'enhancement of self-image in real situation', 'self-growth with self reflection'. In the group-oriented domain, there were 3 kinds of concepts including 'cognitive work in group', 'perception of co-responsibility in attaining learning objectives', 'socialization with group members'. In the practice-oriented domain, there were 3 kinds of concepts including 'linkage theoretical knowledge with real situation', 'attempt to apply in real situation', 'development problem solving skill in real situation'. In conclusion, PBL had a significant effect on self, group, and clinical domain. And assessing PBL outcomes is challenging because standardized instrument do not develop yet. So the findings of this study can suggest the basic data for examining the PBL outcome.

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A comparative study of periodontal conditions around mesially tipped molars by a tipping degree (대구치의 근심 경사 정도에 따른 치주 상태의 비교 연구)

  • Park, So-Young;Choi, Seoung-Hwan;Lee, Su-Jeong;Chang, Moon-Taek;Kim, Hyung-Seop
    • Journal of Periodontal and Implant Science
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    • v.32 no.1
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    • pp.41-49
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    • 2002
  • The aim of this study was to compare periodontal conditions around mesially tipped molars by a tipping degree. Patients who had been consecutively treated at the Department of Periodontology, Chonbuk National University Hospital from October 1999 to August 2001 were assessed with radiographs taken at their molar regions. Of all molars investigated, 142 molars of 116 patients tipped mesially more than 10 degrees to the line perpendicular to an occlusal plane were selected for the study. The tipped molars were divided into 2 groups with a reference to a tipping degree, i.e., 66 slightly tipped(group 1 : <$30^{\circ}$) and 76 severely tipped molars (group 2 : ${\geq}30^{\circ}$). Probing depth(PD), plaque retention index(PRI) at mesial surfaces of tipped molars and tooth mobility(TM) were recorded at the clinical examination. Tipping degree(TD) and alveolar bony defect(ABD) at the mesial surface of the molars were measured in a radiograph. The results showed that no statistical differences were found between groups in all measured variables. In Pearson correlation analysis performed in the same group, a positive relationship was shown between PRI and PD in the group 1 and, in the group 2, between PRI and PD as well as PRI and ABD(p < 0.01). However, no statistically significant relationship was found between TD and all other variables in both groups. Within limitations of this study, it may be concluded that tipping degree did not seem to influence periodontal conditions, i.e., PD, ABD and TM of mesially tipped molars per se, but plaque presence/absence seemed to mainly affect the periodontal conditions of the tipped molars.

Genetic mapping and sequence analysis of Phi class Glutathione S-transferases (BrGSTFs) candidates from Brassica rapa

  • Park, Tae-Ho;Jin, Mi-Na;Lee, Sang-Choon;Hong, Joon-Ki;Kim, Jung-Sun;Kim, Jin-A;Kwon, Soo-Jin;Zang, Yun-Xiang;Park, Young-Doo;Park, Beom-Seok
    • Journal of Plant Biotechnology
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    • v.35 no.4
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    • pp.265-274
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    • 2008
  • Glutathione S-transferases (GSTs) are multifunctional proteins encoded by a large gene family divided into Phi, Tau, Theta, Zeta, Lambda and DHAR classes on the basis of sequence identity. The Phi(F) and Tau(U) classes are plant-specific and ubiquitous. Their roles have been defined as herbicide detoxification and responses to biotic and abiotic stresses. Fifty-two members of the GST super-family were identified in the Arabidopsis thaliana genome, 13 members of which belong to the Phi class of GSTs (AtGSTFs). Based on the sequence similarities of AtGSTFs, 11 BAC clones were identified from Brassica rapa. Seven unique sequences of ORFs designated the Phi class candidates of GST derived from B. rapa (BrGSTFs) were detected from these 11 BAC clones by blast search and sequence alignment. Some of BrGSTFs were present in the same BAC clones indicating that BrGSTFs could also be clustered as usual in plant. They were mapped on B. rapa linkage group 2, 3, 9 and 10 and their nucleotide and amino acid sequences were highly similar to those of AtGSTFs. In addition, in silico analysis of BrGSTFs using Korea Brassica Genome Project 24K oligochip and microarray database for cold, salt and drought stresses revealed 15 unigenes to be highly similar to AtGSTFs and six of these were identical to one of BrGSTFs identified in the BAC clones indicating their expression. The sequences of BrGSTFs and unigenes identified in this study will facilitate further studies to apply GST genes to medical and agriculture purposes.

A Study on Trip Chain Typed Selection Behavior (통행사슬유형 선택행태에 관한 연구)

  • Bin, Mi-Yeong
    • Journal of Korean Society of Transportation
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    • v.29 no.3
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    • pp.7-19
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    • 2011
  • Using 2006 metropolitan household travel survey data, this study analyzes trip behaviors based on a concept of trip chains using both trip purpose and number of trip linkages. For the analysis, trip chains are classified into two groups depending on including commute trips. Each group is further classified into a single linkage (i.e., Origin-Destination trips without any intermediate stop-by) and multiple linkages (Origin-Destination trip with at least one intermediate stop-by). The analysis is conducted using the two-step Nested Logit Model. Computational results identifying the characteristics of single and multiple linkages show that the young, male and office employee drivers tend to have more multiple linkages than single linkages in their trips. In contrast, it is shown that a driver whose monthly income is less than 3,000,000 Korean Won with a longer commute time more likely to make a trip chain with single linkages (p<0.0001).

IT ROI Methodology Development and Application: A Case Study on Financial Company (IT ROI 방법론의 개발 및 적용: L 금융기업 사례를 중심으로)

  • Lee, Jung-Hoon;Park, Gi-Han;Oh, Bu-Yeon
    • Information Systems Review
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    • v.8 no.2
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    • pp.189-209
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    • 2006
  • Business expects that IT investment would maximize the effects, like availability, timeliness, rapidity of information, by practical using of information technology for a strategic goal. However, it is not clear yet that IT investment would increase business productivity and could create profitability in the end-the linkage between IT investment and business KPI(Key Performance Indicator). In this case study(only provides post-evaluation case), we suggested integrated IT ROI(Return On Investment) methodology with a consistent and integrated view, on the base of practical implementation at Korean financial company. Especially, we evaluated connection between IT and business strategy, made business-related IT KPI development methodology, suggested framework for sustainable IT evaluation and management.

Discernment Model of Traffic Accident for an Age-old Driver's License Management (고령운전자 면허관리를 위한 교통사고발생 판별모형 개발)

  • Park, Jun-Tae;Lee, Soo-Beom;Lee, Soo-IL
    • Journal of the Korean Society of Safety
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    • v.26 no.3
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    • pp.91-97
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    • 2011
  • The weight of elderly people in Korea has been increasing. Statistics show that the percentage of the elderly people in Korea was 3.1% in 1970; 3.8% in 1980; 5.1% in 1990, and 7.2% in 2000. Based on this trend, thus, the number of elderly people could be estimated to be 14% of the whole Korean population in 2018. This reveals that Korea is entering a super-aging society with remarkable fast pace. In such a change, the statistics related to elderly people driving license and the occurrence of traffic accidents are showing a noticeable numerical value. The number of traffic accident fatality in Korea ranks the highest value in OECD Countries. However, the research on old drivers in the nation is going on partially centering on system improvement and management scheme. Thus, first of all, researches about the linkage & characteristics between the driving behavior of old drivers and traffic accident should be implemented, in order properly to draw system improvement and management scheme for the old drivers. Therefore, the focus of this study is the influence model for discerning the severity of the age-old-caused traffic accidents by inquiring into the relation between the Driving Aptitude Test items that make it possible to measure their behavioral characteristics and influential factors by age group on the basis of the data on traffic accidents. The analysis results can be used as basic data for suggesting the behavioral research and countermeasure for traffic safety and its management for old driver in preparation for the aging society.

Analysis of Flood Control Capacity of Agricultural Reservoir Based on SSP Climate Change Scenario (SSP 기후변화 시나리오에 따른 농업용 저수지 홍수조절능력 분석)

  • Kim, Jihye;Kwak, Jihye;Hwang, Soonho;Jun, Sang Min;Lee, Sunghack;Lee, Jae Nam;Kang, Moon Seong
    • Journal of The Korean Society of Agricultural Engineers
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    • v.63 no.5
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    • pp.49-62
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    • 2021
  • The objective of this study was to evaluate the flood control capacity of the agricultural reservoir based on state-of-the-art climate change scenario - SSP (Shared Socioeconomic Pathways). 18 agricultural reservoirs were selected as the study sites, and future rainfall data based on SSP scenario provided by CMIP6 (Coupled Model Intercomparison Project 6) was applied to analyze the impact of climate change. The frequency analysis module, the rainfall-runoff module, the reservoir operation module, and their linkage system were built and applied to simulate probable rainfall, maximum inflow, maximum outflow, and maximum water level of the reservoirs. And the maximum values were compared with the design values, such as design flood of reservoirs, design flood of direct downstream, and top of dam elevation, respectively. According to whether or not the maximum values exceed each design value, cases were divided into eight categories; I-O-H, I-O, I-H, I, O-H, O, H, X. Probable rainfall (200-yr frequency, 12-h duration) for observed data (1973~2020) was a maximum of 445.2 mm and increased to 619.1~1,359.7 mm in the future (2011~2100). For the present, 61.1% of the reservoirs corresponded to I-O, which means the reservoirs have sufficient capacity to discharge large inflow; however, there is a risk of overflowing downstream due to excessive outflow. For the future, six reservoirs (Idong, Baekgok, Yedang, Tapjung, Naju, Jangsung) were changed from I-O to I-O-H, which means inflow increases beyond the discharge capacity due to climate change, and there is a risk of collapse due to dam overflow.