• 한국항해항만학회지
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• 제44권6호
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• pp.557-563
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• 2020

디지털 트윈 기술은 다양한 산업에서 적용되고 있으며, 물류 산업에도 큰 영향을 미칠 것으로 예상되지만 컨테이너 터미널에서의 기술 도입은 제한적으로 발전하고 있다. 기존 선행연구를 검토한 결과 컨테이너 터미널을 대상으로 디지털 트윈 기술의 적용에 관한 연구는 미비한 실정이다. 본 연구에서는 컨테이너 터미널에 디지털 트윈 기술 우선 적용 분야를 도출하기 위하여 AHP 분석과 IPA 분석을 실시하였다. IPA 분석을 통해 컨테이너 터미널의 디지털 트윈 기술 적용 분야 세부 요소의 도입 시급성을 분석한 결과 ATC, 지능형 CCTV, 컨테이너 야드가 최우선으로 컨테이너 터미널에 도입이 되어야 할 것으로 판단된다. 다음으로 VR/AR 장비, AYT, 스마트 컨테이너, 컨테이너 자동 순환 시설, 냉동·냉장 컨테이너 야드, 항만용 Wearable 디바이스, 스마트 부표의 순이며, AQC, Berth, AGV, ASC, Apron, 자동 계류기기는 점진적으로 도입이 필요할 것으로 판단된다. 마지막으로 OSS 장비, 인터모달 연계시설, 지능형 드론, 위험물 장치장은 상대적으로 도입 순위에서 후순위에 위치한 것으로 나타났다.

• 대한간호
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• 제33권2호
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• pp.45-58
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• 1994

This study was conducted for the purpose of identifying the trends of nursing research and to suggest the direction of future research in the graduate levels of the study. The data was collected from 469 abstracts of master's and doctoral rapers from three graduate schools, one in Nursing, another in Education, and the other in Public Health Graduate College. The results of the study are as follows: The number of research was increased from 102 to 286 between the 1970 s and 1980's. The most frequently employed research design was descriptive studies in the master's level, but there was some balance between descriptive and experimental studies along with some qualitative approaches in the doctoral thesis. Patients were the most often studied sample group reaching 42% of the cases, though it Was noted that there was steady shift: toward the non-ratient population. With this shifting of the study sample, the places of the study also have showed some changes moving toward community. The most widely studied area was in clinical practice. Chronic illness, preventive, and health promoting areas of studies also increased in numbers. However, most of them were at the descriptive level of phenomena and only a few were concerned with cost/effective measures of nursing intervention. The number of variables studied repeatedly more than five times was 43. They were not only physical but also psychosocial aspects which imply the efforts to incorporate the whole person in nursing discipline. However, most researches with repeated studies showed little relation to previous studies, and thus little accumulation in knowledge. There was also little evidence of linkage to nursing theory in most studies of master's level. For the doctoral rapers, 17 out of 51 rapers showed specific theories related to the researches. Based on the above findings, the following suggestions were made. Various research design should be employed including case studies, historical studies, as well as qualitative approaches. There should be more effort to establish linkage between theory and research. The areas needing more attention are Korean Nursing History, Ethics in our Culture, Cost/Effective Measures of Nursing Intervention, Concept and Thory Development, and the Strategies for the Implication of the Research Results in clinical practice.

• 한국컴퓨터정보학회논문지
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• 제19권10호
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• pp.221-230
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• 2014

이 연구에서는 학생들이 황새 복원과 관련된 주제의 프로젝트를 수행하는 과정에서 여러 학문의 지식을 활용하여 학습능력이 신장될 수 있는 방법을 제안하고자 한다. 개발 프로그램은 3 4학년군, 5 6학년군 각 4차시 총 8차시이며, 각 차시에서 황새와 관련된 초등학교 교과의 지식이나 개념을 기반으로 창의성, 문제해결능력, 의사소통능력 등의 학습능력이 신장될 수 있도록 설계하였다. 프로그램의 타당성 검증을 위해 총 12명으로 구성된 전문가 집단에 내용타당도 검증방법을 사용하였다. 타당성 평가 결과 분석을 위해서 Lawshe(1975)의 내용타당도 비율(Content Validity Ratio: CVR) 계산 공식을 활용하였다. 검증 결과는 전체 8차시의 타당성 조사 결과 3,4학년 4차시 프로그램을 제외하고는 개발 취지에 부합하는 것으로 분석되었다. 3 4학년 4차시 프로그램은 다학문적 연계 영역에 대한 문제점이 제기되었고, 이를 수정하였다. 향후 이 연구에서 제안한 프로그램을 초등학교 학생에게 적용하여 학습능력 향상 효과성 정도를 측정할 필요가 있겠다.

• Asian-Australasian Journal of Animal Sciences
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• 제17권8호
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• pp.1053-1061
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• 2004

Of the 20 arbitrarily chosen primers, six oligonucleotides decamer primers were used on the basis of the number of the polymorphisms generated in catfish (Silurus asotus) from Yesan and bullhead (Pseudobagrus fulvidraco) from Dangjin in Korea. Six primers were used generating a total of 602 scorable bands in catfish and 195 in bullhead population, respectively, ranging in size of DNA fragments from less than approximately 100 to larger than 2,000 base pairs (bp). Six primers yielded 199 polymorphic fragments (33.1%) in catfish and 47 (24%) in bullhead, respectively. In the present study, a total of 328 common fragments (an average of 54.7 per primer) were observed in catfish population, whereas 84 (an average of 14.0 per primer) in bullhead. The total number of specific fragments in catfish and bullhead population were 76 and 64, respectively. In catfish population, random decamer, OPA-17 (GACCGCTTGT) generated the highest number of fragments (a total of 141) in comparison with other primers used, with an average of 11.8. The common bands in the molecular weight of 300 bp generated by random primer OPA-06 (GGTCCCTGAC) were present in every individuals in bullhead population. The major polymorphic bands in the molecular weight of 100 bp generated by OPA-17 were identified in lane 14, 15, 17, 18, 19 20 and 21, which were identifying species in bullhead population. The average bandsharing values (BS values) of all of the samples within catfish population ranged from 0.575 to 0.945, whereas 0.063-1.000 within bullhead population. The bandsharing value (index of similarity between individuals) between individual No. 5 and No. 9 showed the highest level within catfish population, whereas the bandsharing value between individual No. 1 and No. 2 showed the lowest level. The single linkage cluster analysis resulted from four primers, indicating four genetic groupings composed of group 1 (C1-C10, all of the catfish samples), group 2 (B11, B12, B13, B14, B16, B17, B18, B19), group 3 (B15) and group 4 (B20 and B21). The dendrogram reveals close relationships between individual identities within two species populations and individuals derived from the same ancestor, respectively. However, genetic distances between two species populations ranged from 0.124 to 0.333. The shortest genetic distance (0.042) displaying significant molecular differences was between individual No. 6 and No. 9 catfish population. The shortest genetic distance (0.033) displaying significant molecular differences also was between individual No. 18 and No. 19 in bullhead population. Reversely, the genetic distance of individual No. 20/21 among individuals in bullhead population was highest (0.333). This result showed that bullhead No. 20 and 21 were distinct from other individuals within bullhead population.

• Applied Biological Chemistry
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• 제17권2호
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• pp.125-137
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• 1974

Selenomonas ruminantium 균체(菌體)를 TCA로 가열(加熱) 분해(分解)한 후 chloroform : methanol (1 : 3)로 추출(抽出)한 당지질(糖脂質)을 분리(分離)하고 이 당지질(糖脂質)을 acetone가용부분(可溶部分) spot A화합물(化合物)과 acetone불용부분(不溶部分)에서 ether로 다시 가용부분(可溶部分)을 추출(抽出)한 spot B화합물(化合物)의 두 부분(部分)으로 분리(分離)하고 이 두 화합물(化合物)에 대(對)하여 각각(各各) 그 화학구조(化學構造)를 구명(究明)하며 당지질(糖脂質)의 구조(構造)를 추정(推定)한 바 다음과 같은 결과(結果)를 얻었다. 1. 두 화합물(化合物)의 적외선흡수분석결과(赤外線吸收分析結果) spot A는 amino당(糖)에 O-acyl 및 N-acyl지방산(脂肪酸)이 결합(結合)하였으며 spot B는 amino당(糖)에 O-acyl 및 N-acyl지방산(脂肪酸)이 결합(結合)하고 인(燐)을 함유(含有)하고 있음을 알았다. 2. 두 화합물(化合物)을 GLC에 의(依)하여 지방산조성(脂肪酸組成)을 조사(調査)한 바 spot A.B화합물중(化合物中)에 있는 O-acyl 및 N-acyl 지방산(脂肪酸)은 ${\beta}-OH\;C_{13:0}$지방산(脂肪酸)이 대부분(大部分)이 였는데 저급(低級)의 hydroxy지방산(脂肪酸) ${\beta}-OH\;C_{9:0}$도 특이적(特異的)으로 함유(含有)되여 있음을 알았다. 3. 두 화합물(化合物)을 hydrazine분해(分解)를 시킨 결과(結果)를 paper chromatography로 조사(調査)한 바 spot A화합물(化合物)은 glucosamine 이 2분자(分子) 결합(結合)하여 있는 chitobiose와 같은 Rf 치(値)를 나타냈음으로 2분자(分子)의 glucosamine이 결합(結合)됨을 확인(確認)하고 spot B 화합물(化合物)의 낮은 Rf치(値)는 glucosamine에 인(燐)이 결합(結合)되여 있음을 알았다. 4. spotA화합물(化合物)의 산분해물(酸分解物)을 다시 ninbydrine으로 산화분해(酸化分解) 시키면 arabinose만이 생기는 것으로 보아 glucosamine의 amino기(基)는 $C_2$의 위치(位置)에 결합(結合)하여 있음을 알았다. 5. N-acetyl화(化)한 spot A에 $NaBH_4$를 추리(處理)한 결과(結果) glucosamine의 전량(全量)이 반감(半減)하는 것으로 보아 2분자(分子)의 glucosamine이 결합(結合)되여 있는 것을 알 수 있고 Morgan-Elson반응(反應) 및 $NaIO_4$분해(分解)에 의(依)하여 2개(個)의 glucosamine은 1.6결합(結合)임을 확인(確認)하였다. 6. N-acetyl화(化)한 spot A.B화합물(化合物)에 ${\beta}-N-acetyl$ glucosarninidase를 반응(反應)시킨 결과(結果) spot A화합물(化合物)은 100% N-acetyl glucosamine으로 분해(分解)되고 spot B화합물(化合物)은 분해(分解)되지 않았으므로 spot A화합물(化合物)만이 ${\beta}$결합(結合)을 하고 있음을 알았다. 7. $^{32}P$함유(含有) spot B화합물(化合物)에 phosphodiesterase 및 phosphomonoesterase를 작용(作用)시킨 결과(結果) phosphodiesterase는 반응(反應)치 않고 phosphomonoesterase에 의(依)하여 100% $^{32}P$가 유리(遊離)되는 것으로 보아 glucosamine 2분자(分子)에 한계의 인(燐)이 monoester결합(結合)을 하고 있음을 알 수 있다. 8. spot A화합물(化合物)은 glucosaminiyl ${\beta}-1.6-glucosamine$의 결합(結合)을 하였고 O-acyl 및 N-acyl지방산(脂肪酸)이 결합(結合)되여 있으며 주지방산(主脂肪酸)은 ${\beta}-OH\;C_{13:0}$임을 알았다. 9. spot B화합물(化合物)도 glucosaminyl ${\beta}-1.6-glucosamine$의 결합(結合)을 하고 O-acyl 및 N-acyl지방산(脂肪酸)이 결합(結合)되여 있으며 주지방산(主脂肪酸)은 ${\beta}-OH\;C_{13:0}$이나 인(燐)이 monoester결합(結合)을 하고 있는 것이 spot A화합물(化合物)과 특이(特異)함을 알았다.

• Safety and Health at Work
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• 제8권3호
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• pp.258-266
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• 2017

Background: Welders are exposed to many known and suspected carcinogens. An excess lung cancer risk among welders is well established, but whether this is attributable to welding fumes is unclear. Excess risks of other cancers have been suggested, but not established. We investigated welding cancer risks in the population-based Canadian Census Health and Environmental Cohort. Methods: Among 1.1 million male workers, 12,845 welders were identified using Standard Occupational Classification codes and followed through retrospective linkage of 1991 Canadian Long Form Census and Canadian Cancer Registry (1992-2010) records. Hazard ratios (HRs) were calculated using Cox proportional hazards models based on estimated risks of lung cancer, mesothelioma, and nasal, brain, stomach, kidney, and bladder cancers, and ocular melanoma. Lung cancer histological subtypes and risks by industry group and for occasional welders were examined. Some analyses restricted comparisons to blue-collar workers to minimize effects of potential confounders. Results: Among welders, elevated risks were observed for lung cancer [HR: 1.16, 95% confidence interval (CI): 1.03-1.31], mesothelioma (HR: 1.78, 95% CI: 1.01-3.18), bladder cancer (HR: 1.40, 95% CI: 1.15-1.70), and kidney cancer (HR: 1.30, 95% CI: 1.01-1.67). When restricted to blue-collar workers, lung cancer and mesothelioma risks were attenuated, while bladder and kidney cancer risks increased. Conclusion: Excess risks of lung cancer and mesothelioma may be partly attributable to factors including smoking and asbestos. Welding-specific exposures may increase bladder and kidney cancer risks, and particular sources of exposure should be investigated. Studies that are able to disentangle welding effects from smoking and asbestos exposure are needed.

• Annals of Clinical Neurophysiology
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• 제6권2호
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• pp.65-74
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• 2004

Limb-girdle muscular dystrophy (LGMD) is a heterogeneous group of inherited muscle disorders caused by the mutations of different genes encoding muscle proteins. In the past, when the molecular diagnostic techniques were not available, the subtypes of muscular dystrophies were classified by the pattern of muscle weakness and the mode of inheritance, and LGMD had been considered as a 'waste basket' of muscular dystrophy because many unrelated heterogeneous cases with 'limb-girdle' weakness were put into the category of LGMD. With the advent of molecular genetics at the end of the last century, it has been known that there are many subtypes of LGMD caused by the mutation of different genes, and now, LGMD is classified according to the results of the linkage analysis and the genes or proteins affected. Only small proportion (probably less than 10%) of LGMD is dominantly inherited, and autosomal dominant LGMD (AD-LGMD) consists of six subtypes (LGMD1A to 1F) so far. In autosomal recessive LGMD (AR-LGMD), more than 10 subtypes (LGMD2A to 2J) have been linked and most of the causative genes have been identified. Among AR-LGMDs, LGMD2A (calpain 3 deficiency), 2B (dysferlin deficiency), and sarcoglycanopathy (LGMD2C-2F) are major subtypes. The defective proteins in LGMDs are components of nuclear envelope, cytosol, sarcomere, or sarcolemma, and seem to play a different role in the pathogenesis of muscular dystrophy. It is notable that many causative genes of LGMDs are also responsible for other categories of muscular dystrophy or diseases affecting other tissue. However, by which mechanism they produce such a broad phenotypic variability is still unknown. The identification of mutation in the relevant gene is confirmative for the diagnosis, and is essential for genetic counseling and antenatal diagnosis of LGMD. Because many different genes are responsible for LGMD, differentiation of subtypes using immunohistochemistry and western blotting is the essential step toward the detection of mutation. For the effective research and medical care of the patients with muscular dystrophy in Korea, a research center with a medical facility supported by the government seems to be needed.

• 에너지공학
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• 제21권1호
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• pp.109-117
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• 2012

기후산업은 세계기후변화협약에 대응할 수 있는 산업으로서 기후변화를 창출하거나 이에 대응하는 모든 산업군으로 정의될 수 있다. 본 논문은 그중 신재생에너지산업에 한정하여, 2011년 한국은행에서 발표한 2009년 산업연관표를 활용하여 경제적 파급효과를 분석하였다. 분석의 결과, 2009년 현재 한국 신재생에너지산업은 1원의 생산량 증가를 통해 1.1644원의 생산을 유발하였으며, 0.3544원의 부가가치를 유발한 것으로 분석된다. 취업유발효과는 10억원의 생산량 증가를 통해 10.065명의 취업을 유발한 것으로 분석된다. 그리고 산업구조 전체 속에서 신재생에너지산업의 상대적 위치를 설정하는 산업연쇄효과는 아직 크지 않은 것으로 나타났다. 향후 신성장동력으로 지정한 신재생에너지산업을 활성화하기 위해서는 부가가치를 제고하기 위한 정책이 더욱 활발하게 추진되고, 신재생에너지산업의 부가가치사슬망(value-chain)에 관련된 산업들에 대한 정책도 함께 마련되어야 할 것으로 판단된다.

• Journal of Microbiology and Biotechnology
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• 제19권9호
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• pp.851-857
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• 2009

We developed and characterized 36 polymorphic microsatellite markers for the oyster mushroom (Pleurotus ostreatus). In total, 169 alleles were identified with an average of 4.7 alleles per locus. Values for observed ($H_o$) and expected ($H_E$) heterozygosities ranged from 0.027 to 0.946 and from 0.027 to 0.810, respectively. Nineteen loci deviated from Hardy-Weinberg equilibrium. Significant (P<0.05) excess heterozygosity was observed at nine loci. Linkage disequilibrium (LD) was significant (P<0.05) between pairs of locus alleles. Cluster analysis revealed that five species of genus Pleurotus made a distinct group, and the individual cultivars were grouped into major five groups from G-1 to G-5. The diverse cultivars of P. ostreatus were discriminated and the other four species revealed a different section in the UPGMA tree. These microsatellite markers proved to be very useful tools for genetic studies, including assessment of the diversity and population structure of P. ostreatus.

• 한국산학기술학회논문지
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• 제15권6호
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• pp.3907-3915
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• 2014

본 연구는 장기 미집행 도시공원 해소를 위한 정책구성요인을 평가함으로써 향후 정책수행을 위한 시사점을 제시하는데 그 목적이 있다. 본 연구의 정책요인 평가는 장기 미집행 도시 군계획시설 혹은 도시공원과 관련된 업무를 담당하는 전문가 집단을 대상으로 시행되었으며, 그 절차는 정책요인의 선정, 정책요인 간 가중치 산정, 평가결과의 해석이라는 세단계로 구성되었다. 평가의 결과, 전문가들은 정책요인 중 국고보조금 확보(0.183), 지방재정계획과 단계별 집행계획의 연계(0.165), 장기 미집행 도시공원의 선별적 존치(0.154), 국유지 무상 양여 및 장기 임대(0.110)와 같은 요인을 상대적으로 중요하게 평가하였다. 향후 도시공원 일몰제의 시행에 앞서 장기 미집행 도시공원 해소를 위한 폭넓고 심도 있는 논의가 이루어질 필요성이 제기된다.