• 한국약용작물학회지
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• 제13권1호
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• pp.30-34
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• 2005

경남지역 자생 둥글레속 수집종의 유연관계를 규명하여 품종육성을 위한 기초자료로 할용하고자 47개 수집종의 12개 형질을 대상으로 주성분 분석 및 average linkage cluster 방법으로 군을 분류한 결과는 다음과 같다. 1. 주성분 분석에서 줄기형태, 줄기색깔, 엽색, 포의 형태, 화색, 화형 등 12개 주요 형질의 주성분의 고유치에 기여율은 제3주성분까지 분석하여도 전체의 79%정도 설명할 수 있어서 47개 수집종의 분류가 가능함을 알 수 있었다. 2. 47개 수집종의 12개 주요형질을 대상으로 average linkage cluster 방법에 의한 분석치으 거리 0.7을 기준으로 군을 분류한 결과 5개군으로 분류되었다. I군은 둥굴레, II군은 용둥글레, III군은 산둥굴레 및 퉁둥굴레 특성의 중간형태를 각각 지닌 p28과 p29였으며, 제V군은 죽대로 분류되었다. 3. 경남일대 둥굴레의 특성조사와 수집종 분류결과 둥굴레와 죽대는 종간 변이가 거의 없었던 반면, 용둥굴레, 퉁둥굴레와 산둥굴레는 다양한 변이종이 분포하고 있는 것으로 나타났다.

• International Journal of Industrial Entomology and Biomaterials
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• 제11권1호
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• pp.49-55
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• 2005

Two BC1 group, c108 $\times$ (p50 $\times$ c108) and p50 $\times$ (p50 $\times$ c108), one group of F$_{2}$ progeny, (p50 $\times$ c108) F$_{2}$ ,and 3 SSR markers, F10539, FlO626 and FlO618 were used to test the hereditary properties of SSR markers in silkworm. FI0539, FlO626 were proved to be linkage, and FlO618 was proved to be independent to those two markers. According to Mendel's law, the recombinant value between F10539, FlO626 was calculated in all of these groups, and they were 8.55$\%$ (c108BC1), 8.02$\%$ (p50BC1) and 7.81 $\%$ (F$_{2}$) respectively. There was dominant difference among the crossing-over value using paired-samples tests by SPSS 10.0 software. This research proved that SSR markers were co-dominant in B. mori too, and F 2 progeny could be used to construct SSR linkage map although B. mori lacked of crossing over in females.

• Journal of Preventive Medicine and Public Health
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• 제14권1호
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• pp.33-38
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• 1981

During 2 months from December 1979 to January 1980, Medical practitioners in Chonnam province were grouped into Si (city), Eup (town) and Myun (rural area) groups according to the locations of their clinic. 40 practitioners were randomly selected in each group and were asked their opinions about rural medical care in general. Total of 88 practitioners replied to the question as 73.9 percent of response rate in average. The most frequently mentioned advantages of rural practice were ease of clinic opening in Si-and Myun-group respondents and good social relationship in Eup-group respondents. The most frequently mentioned disadvantages were medical isolation in Si-group respondents and residents' ignorance in medicine in Eup-and Myun-group respondents. In all groups, most respondents thought that rural medical care should be delivered by and controlled by physician. Suggestions made by Eup-and Myun-group respondents for improving rural medical care by structural change focused on the regional medical insurance system, while Si-group respondents noted district hospital or hospital linkage as the most preferrable system.

• Genomics & Informatics
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• 제7권3호
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• pp.152-158
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• 2009

Although the genetic basis for bone mineral density (BMD) has been studied by many groups so far, genes responsible for this complex trait has not been completely revealed. In order to localize quantitative trait loci (QTLs) for BMD variation in Asian population, the study was designed using a group of Mongolian population, a genetically closed population with a homogeneous lifestyle. BMD was measured at the left and right wrists and ankles using DEXA in 1,082 participants from 142 families. Genotyping of 13 polymorphic microsatellite markers on chromosome 13 (average spacing 8-9 cM) and two-point and multipoint linkage analysis were performed. In two-point linkage analysis, we identified two markers, D13S175 (6.03 cM) and D13S265 (68.73 cM) that had LOD scores greater than 1 for left ankle (LOD=2.09, LOD=1.49, respectively). We also found a marker D13S175 (6.03 cM) with a high LOD for left wrist (LOD=1.49) and the markers D13S265 (68.73 cM) and D13S217 (17.21 cM) for the right wrist (LOD= 1.82, LOD= 1.62, respectively). Among these significant marker regions, only two regions at 17 cM (13p11) and 65 cM (13q21) for the right wrist overlapped with major QTLs reported in following multipoint linkage analysis (LOD= 1.7549, LOD=1.4462, respectively). This study provides the possible evidence of the presence of QTLs affecting right wrist BMD in Mongolian populations on 13p11 and 13q21. Modest evidence was also found for genes affecting left ankle and left wrist BMD on 13p13.

• Journal of Preventive Medicine and Public Health
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• 제44권4호
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• pp.185-189
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• 2011

Objectives: In 1995, an outbreak survey in Gozan-dong concluded that an association between fiberglass exposure in drinking water and cancer outbreak cannot be established. This study follows the subjects from a study in 1995 using a data linkage method to examine whether an association existed. The authors will address the potential benefits and methodological issues following outbreak surveys using data linkage, particularly when informed consent is absent. Methods: This is a follow-up study of 697 (30 exposed) individuals out of the original 888 (31 exposed) participants (78.5%) from 1995 to 2007 assessing the cancer outcomes and deaths of these individuals. The National Cancer Registry (KNCR) and death certificate data were linked using the ID numbers of the participants. The standardized incidence ratio (SIR) and standardized mortality ratio (SMR) from cancers were calculated by the KNCR. Results: The SIR values for all cancer or gastrointestinal cancer (GI) occurrences were the lowest in the exposed group (SIR, 0.73; 95% CI, 0.10 to 5.21; 0.00 for GI), while the two control groups (control 1: external, control 2: internal) showed slight increases in their SIR values (SIR, 1.18 and 1.27 for all cancers; 1.62 and 1.46 for GI). All lacked statistical significance. All-cause mortality levels for the three groups showed the same pattern (SMR 0.37, 1.29, and 1.11). Conclusions: This study did not refute a finding of non-association with a 13-year follow-up. Considering that many outbreak surveys are associated with a small sample size and a cross-sectional design, follow-up studies that utilize data linkage should become standard procedure.

• 한국융합학회논문지
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• 제13권3호
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• pp.227-237
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• 2022

융합에 관한 관심이 고조되면서 융합을 측정하고자 하는 다양한 시도들이 이루어지고 있으나, 융합의 정의가 모호하고, 측정 지표에 대한 컨센선스가 이루어지지 않아 융합의 측정에 대해서는 더욱 많은 연구가 필요한 상황이다. 본 연구에서는 한국특허청에서 특허와 경제, 산업, 인구 등과의 영향도 및 상관관계를 분석할 수 있도록 개발한 산업(KSIC)-특허(IPC) 연계표를 이용하여 특허 데이터로부터 산업융합을 평가할 수 있는 신규 평가 모형을 제안하고, 이로부터 도출된 산업융합이 기업의 융합특성을 제대로 반영하는지를 여부를 실증하였다. 글로벌 주요 자동차 기업들이 보유한 39,740건 특허의 융합여부를 각각 분류하고, 각 기업의 융합도를 평가한 결과, KSIC-IPC 연계표를 이용하여 도출된 산업융합은 동시분류분석으로 분류된 기술융합보다 기업의 융합특성을 보다 잘 반영한다는 것을 확인할 수 있었다. 따라서 KSIC-IPC 연계표를 이용한 신규 산업융합 평가모델로부터 도출된 자동차 분야 산업융합 자료는 향후 융합연구에 널리 활용될 수 있을 것으로 기대된다.

• Journal of Photoscience
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• 제9권2호
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• pp.261-263
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• 2002

The presence of retinals (retinal and 3,4-didehydroretinal) has been known in the eggs of wide range of oviparous vertebrates, but the biological significance of the egg retinals has yet to be clarified. We here show that retinals are the major components of retinoids in the eggs of all species of chordate animals we examined. The egg retinals were commonly bound to egg yolk proteins, the storage proteins, via a Schiff base linkage. The Schiff base linkage, which protects the reactive aldehyde group, would negate the toxicity of aldehyde, and enable to accumulate much amount of retinals. The retinals in chordate eggs are considered to be the precursor of functional retinoids, such as photoreceptive pigment chromophores and retinoic acid, during development. The results of the present research strongly suggest that retinals in the eggs of oviparous chordates are the common and essential mode of retinoid storage.

• Bulletin of the Korean Chemical Society
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• 제20권10호
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• pp.1149-1152
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• 1999

1H NMR spectrum of a DMF-d7 solution containing 4-aminopyrimidine and [SiW11CoIIO39]6- (SiW11Co) shows separate peaks from two linkage isomers, a and b, in which N(1) and N(3) of the pyrimidine ring are coordinated to SiW11Co, respectively. The signal from the amine group in the isomer a exhibits temperature dependence that is characteristic of a two-site exchange problem. Rates of internal rotation of the amine group were determined by simulating the NMR spectra at 5-35℃. The amine group of free 4-aminopyrimidine also shows temperature-dependent spectra at lower temperatures; rates of internal rotation at (-25)-25℃ were determined. The internal rotation of the amine group in the complex is much slower than that for free 4-aminopyrimidine, indicating that π-character of the C-N bond increases on coordination to SiW11Co. The amine group in the isomer b does not show such behavior. It is probable that hydrogen bonding between N-H and a bridging oxygen atom of SiW11Co prevents it from rotating at low temperatures.

• 한국정보시스템학회지:정보시스템연구
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• 제31권1호
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• pp.239-269
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• 2022

Purpose This paper attempts to identify items for improving the usage of PLM(Product Lifecycle Management) systems and suggests ways to prioritize improvement items on the basis of importance. It also tries to find out differences in the importance of improvement items due to the company size, the industry, the job, or the PLM solution. Design/methodology/approach Through a survey from participants to a PLM System Conference, data were collected from a sample of 181 users who had the previous experience in using a PLM system. In order to figure out the differences in the importance among user groups, the F-test with the Scheffe test as a post-hoc analysis was used in case of equal variances and the Welch test with the Dunnett T3 test was used in case of unequal variances. Findings This study sorted out 25 improvement ideas according to their importance assessed by the PLM system users. The top five ideas are improving data consistency, error minimization, fast system response time, enhancing user recognition, and business process improvement. The support group puts higher importance than the general user group in data consistency, fast system response time, enhancing user recognition, business process improvement, dedicated team for data consistency, continuous support from management, hardware performance upgrade, output linkage to other systems, and shortening problem solving duration. The largest company group attaches significantly higher weights than the smallest company group to data consistency, error minimization, fast system response time, business process improvement, dedicated team for data consistency, security with proper access management, output linkage to other systems, and better user interface.

• 한국콘텐츠학회논문지
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• 제19권5호
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• pp.48-63
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• 2019

본 연구는 한국기업정보(주)에서 제공받은 2015년도의 5만 여개의 최신 기업정보를 활용하여 전자업체를 중심으로 거래 네트워크를 생성하여, 사회네트워크 분석을 포함한 새로운 분석을 시도하였다. 그 결과 97개의 10개 이상 기업으로 이루어진 클러스터들이 발견되었고, 전자산업 매출의 90% 이상을 차지하는 13개의 클러스터들을 주목하게 되었다. 사회네트워크 분석에서의 클러스터들은 소속 기업들이 해당 클러스터 안에서 거래를 완결하는 특성을 가지고 있다. 13개 클러스터들을 보면, 매출액이 많은 상위 5개 클러스터에 전자매출의 83%가 집중되어 있으며, 일부 예외를 제외하고는 각각의 클러스터들은 특정업체가 매출의 대부분을 차지한다. 그렇지만 이들 이외에도 후방생산연관효과가 특별히 높은 업체들도 발견하였으며, 중소기업에 미치는 영향력이 특히 큰 전자 업체들도 눈에 뜨인다. 후방생산연관효과가 높은 업체들은 성장 정책적인 측면에서, 그리고 중소기업에 영향력을 많이 미치는 전자업체들은 중소기업 육성 정책적인 측면에서 중시되어야 할 것이다. 그리고 작은 클러스터들의 합인 마지막 기업군은 매출 대비 고용이 매우 높은 특성을 지닌다는 사실도 발견하였다. 이 기업군에 높은 생산연관효과를 보이는 기업군과 전자업체들이 발견되었으며, 이들은 고용정책적 측면에서 중시될 필요가 있다. 거래를 중계하는 네트워크 특성인 사이중심성이 매출과 비례하지 않게 특별히 높은 클러스터들도 발견하였다. 사이 중심성이 높은 이들 클러스터들은 기술 발전의 가능성이 큰 기업 그룹들이기에 주목할 필요가 있다.