• Title/Summary/Keyword: Linkage group

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Interspecific Relationship of Polygonatum Species Collected from Gyeongnam Area Using Cluster Analysis (경남지역 둥굴레속의 Cluster 분석에 의한 종간 유연관계)

  • Shim, Jae-Suk;Park, Jeong-Min;Jeon, Byong-Sam;Kang, Jin-Ho
    • Korean Journal of Medicinal Crop Science
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    • v.13 no.1
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    • pp.30-34
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    • 2005
  • Polygonatum species are a useful medical crop in Korea but basic study in the species was not well conducted. The study was carried out to analyse genetic diversity and intraspecific relationship of 47 Polygonatum species collected from Gyeongnam province. Their analysis was done through principle component analysis and average linkage cluster analysis with their twelve morphological traits. The result of principle component analysis showed the Prin 1, Prin 2 and Prin 3 represented 79% of total variation. By the 0.7 average distance of the cluster analysis and the calculated Euclidian distance, the 47 collected species were grouped into five groups. Group I included 22 collected species representing P. ordoratum var. pluriflorum, group II did 5 ones representing P. involucratum, group III was divided into two subclasses, 2 species including P. inflatum and 7 species including P. thunbergii, group IV also consisted of 2 subclasses, a species similar to P. thunbergii and P.involucratum, respectively, and finally group V included 8 species representing P.lasianthum var. coreanum. meaning that the useful germplasms can be collected from relatively small area.

Studies on the Hereditary Properties of SSR Marker in Silkworm (Bombyx mori L.)

  • Li Muwang;Li Minghui;Miao Xuexia;Lu Cheng;Huang Yongping
    • International Journal of Industrial Entomology
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    • v.11 no.1
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    • pp.49-55
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    • 2005
  • Two BC1 group, c108 $\times$ (p50 $\times$ c108) and p50 $\times$ (p50 $\times$ c108), one group of F$_{2}$ progeny, (p50 $\times$ c108) F$_{2}$ ,and 3 SSR markers, F10539, FlO626 and FlO618 were used to test the hereditary properties of SSR markers in silkworm. FI0539, FlO626 were proved to be linkage, and FlO618 was proved to be independent to those two markers. According to Mendel's law, the recombinant value between F10539, FlO626 was calculated in all of these groups, and they were 8.55$\%$ (c108BC1), 8.02$\%$ (p50BC1) and 7.81 $\%$ (F$_{2}$) respectively. There was dominant difference among the crossing-over value using paired-samples tests by SPSS 10.0 software. This research proved that SSR markers were co-dominant in B. mori too, and F 2 progeny could be used to construct SSR linkage map although B. mori lacked of crossing over in females.

Opinions of Medical Practitioners in a Local Area about Rural Medical Care Practices (일부지방(一部地方) 개업의(開業醫)들의 농촌의료(農村醫療)에 대(對)한 의견(意見))

  • Choi, Jin-Su
    • Journal of Preventive Medicine and Public Health
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    • v.14 no.1
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    • pp.33-38
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    • 1981
  • During 2 months from December 1979 to January 1980, Medical practitioners in Chonnam province were grouped into Si (city), Eup (town) and Myun (rural area) groups according to the locations of their clinic. 40 practitioners were randomly selected in each group and were asked their opinions about rural medical care in general. Total of 88 practitioners replied to the question as 73.9 percent of response rate in average. The most frequently mentioned advantages of rural practice were ease of clinic opening in Si-and Myun-group respondents and good social relationship in Eup-group respondents. The most frequently mentioned disadvantages were medical isolation in Si-group respondents and residents' ignorance in medicine in Eup-and Myun-group respondents. In all groups, most respondents thought that rural medical care should be delivered by and controlled by physician. Suggestions made by Eup-and Myun-group respondents for improving rural medical care by structural change focused on the regional medical insurance system, while Si-group respondents noted district hospital or hospital linkage as the most preferrable system.

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Localization of Quantitative Trait Loci for Bone Mineral Density on Chromosome 13 in the Mongolian Population

  • Seo, Soo-Hyun;Lim, Hae-Jeng;Ahn, Se-Jin;Lee, Joseph;Kim, Jong-Il
    • Genomics & Informatics
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    • v.7 no.3
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    • pp.152-158
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    • 2009
  • Although the genetic basis for bone mineral density (BMD) has been studied by many groups so far, genes responsible for this complex trait has not been completely revealed. In order to localize quantitative trait loci (QTLs) for BMD variation in Asian population, the study was designed using a group of Mongolian population, a genetically closed population with a homogeneous lifestyle. BMD was measured at the left and right wrists and ankles using DEXA in 1,082 participants from 142 families. Genotyping of 13 polymorphic microsatellite markers on chromosome 13 (average spacing 8-9 cM) and two-point and multipoint linkage analysis were performed. In two-point linkage analysis, we identified two markers, D13S175 (6.03 cM) and D13S265 (68.73 cM) that had LOD scores greater than 1 for left ankle (LOD=2.09, LOD=1.49, respectively). We also found a marker D13S175 (6.03 cM) with a high LOD for left wrist (LOD=1.49) and the markers D13S265 (68.73 cM) and D13S217 (17.21 cM) for the right wrist (LOD= 1.82, LOD= 1.62, respectively). Among these significant marker regions, only two regions at 17 cM (13p11) and 65 cM (13q21) for the right wrist overlapped with major QTLs reported in following multipoint linkage analysis (LOD= 1.7549, LOD=1.4462, respectively). This study provides the possible evidence of the presence of QTLs affecting right wrist BMD in Mongolian populations on 13p11 and 13q21. Modest evidence was also found for genes affecting left ankle and left wrist BMD on 13p13.

Fifteen Years After the Gozan-Dong Glass Fiber Outbreak, Incheon in 1995

  • Cho, Soo-Hun;Sung, Joo-Hon;Kim, Jong-Hoon;Ju, Young-Su;Han, Min-Ji;Jung, Kyu-Won
    • Journal of Preventive Medicine and Public Health
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    • v.44 no.4
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    • pp.185-189
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    • 2011
  • Objectives: In 1995, an outbreak survey in Gozan-dong concluded that an association between fiberglass exposure in drinking water and cancer outbreak cannot be established. This study follows the subjects from a study in 1995 using a data linkage method to examine whether an association existed. The authors will address the potential benefits and methodological issues following outbreak surveys using data linkage, particularly when informed consent is absent. Methods: This is a follow-up study of 697 (30 exposed) individuals out of the original 888 (31 exposed) participants (78.5%) from 1995 to 2007 assessing the cancer outcomes and deaths of these individuals. The National Cancer Registry (KNCR) and death certificate data were linked using the ID numbers of the participants. The standardized incidence ratio (SIR) and standardized mortality ratio (SMR) from cancers were calculated by the KNCR. Results: The SIR values for all cancer or gastrointestinal cancer (GI) occurrences were the lowest in the exposed group (SIR, 0.73; 95% CI, 0.10 to 5.21; 0.00 for GI), while the two control groups (control 1: external, control 2: internal) showed slight increases in their SIR values (SIR, 1.18 and 1.27 for all cancers; 1.62 and 1.46 for GI). All lacked statistical significance. All-cause mortality levels for the three groups showed the same pattern (SMR 0.37, 1.29, and 1.11). Conclusions: This study did not refute a finding of non-association with a 13-year follow-up. Considering that many outbreak surveys are associated with a small sample size and a cross-sectional design, follow-up studies that utilize data linkage should become standard procedure.

Research on Idustrial Convergence Evaluation Model Using KSIC-IPC: Focusing on the automotive sector (KSIC-IPC를 이용한 산업융합 평가모형 연구: 자동차 분야를 중심으로)

  • Lee, Haeng Byoung;Han, Kyu-Bo;Lee, Jung Hoon
    • Journal of the Korea Convergence Society
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    • v.13 no.3
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    • pp.227-237
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    • 2022
  • With the growing interest in convergence, there have been various attempts to measure convergence, but the definition of convergence is ambiguous and consensus on appropriate indicators has not been reached, so measurement of convergence is still at a rudimentary stage. In this study, using the KSIC-IPC linkage table developed by the Korean Intellectual Property Office to analyze the correlation and impact of patents, industry, economy, and population, we propose a new evaluation model that can evaluate industry convergence from patent data. In addition, it was verified whether the industry convergence derived from this properly reflects the corporate convergence characteristics. As a result of classifying the convergence of 39,740 patents owned by global major automobile companies, and evaluating the degree of convergence of each company, it was confirmed that the industry convergence derived using the KSIC-IPC linkage table better reflects the corporate convergence characteristics than the technology convergence classified by IPC co-classification. Therefore, the industry convergence data of automotive sector derived from the new industry convergence evaluation model using the KSIC-IPC linkage table is expected to be widely used for future convergence research.

Retinal in the Eggs of Phylum Chordata: A Novel Storage Mode of Retinoid

  • lrie, Toshiaki;Seki, Takaharu;Azuma, Masami;Kajiwara, Shogo
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.261-263
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    • 2002
  • The presence of retinals (retinal and 3,4-didehydroretinal) has been known in the eggs of wide range of oviparous vertebrates, but the biological significance of the egg retinals has yet to be clarified. We here show that retinals are the major components of retinoids in the eggs of all species of chordate animals we examined. The egg retinals were commonly bound to egg yolk proteins, the storage proteins, via a Schiff base linkage. The Schiff base linkage, which protects the reactive aldehyde group, would negate the toxicity of aldehyde, and enable to accumulate much amount of retinals. The retinals in chordate eggs are considered to be the precursor of functional retinoids, such as photoreceptive pigment chromophores and retinoic acid, during development. The results of the present research strongly suggest that retinals in the eggs of oviparous chordates are the common and essential mode of retinoid storage.

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$^1H$ NMR Study of 4-Aminopyrimidine Coordinated to the Paramagnetic Undecatung-stocobalto(Ⅱ)silicate Anion: Rates of Internal Rotation of the Amine Group

  • 김병안;소현수
    • Bulletin of the Korean Chemical Society
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    • v.20 no.10
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    • pp.1149-1152
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    • 1999
  • 1H NMR spectrum of a DMF-d7 solution containing 4-aminopyrimidine and [SiW11CoIIO39]6- (SiW11Co) shows separate peaks from two linkage isomers, a and b, in which N(1) and N(3) of the pyrimidine ring are coordinated to SiW11Co, respectively. The signal from the amine group in the isomer a exhibits temperature dependence that is characteristic of a two-site exchange problem. Rates of internal rotation of the amine group were determined by simulating the NMR spectra at 5-35℃. The amine group of free 4-aminopyrimidine also shows temperature-dependent spectra at lower temperatures; rates of internal rotation at (-25)-25℃ were determined. The internal rotation of the amine group in the complex is much slower than that for free 4-aminopyrimidine, indicating that π-character of the C-N bond increases on coordination to SiW11Co. The amine group in the isomer b does not show such behavior. It is probable that hydrogen bonding between N-H and a bridging oxygen atom of SiW11Co prevents it from rotating at low temperatures.

A Study on the Importance of Measures for Improving PLM System Usage (PLM 시스템 활용도 향상 방안의 중요도에 관한 연구)

  • Yoo, Jong Kwang;Rim, Seong Taek;Min, Dai Hwan
    • The Journal of Information Systems
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    • v.31 no.1
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    • pp.239-269
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    • 2022
  • Purpose This paper attempts to identify items for improving the usage of PLM(Product Lifecycle Management) systems and suggests ways to prioritize improvement items on the basis of importance. It also tries to find out differences in the importance of improvement items due to the company size, the industry, the job, or the PLM solution. Design/methodology/approach Through a survey from participants to a PLM System Conference, data were collected from a sample of 181 users who had the previous experience in using a PLM system. In order to figure out the differences in the importance among user groups, the F-test with the Scheffe test as a post-hoc analysis was used in case of equal variances and the Welch test with the Dunnett T3 test was used in case of unequal variances. Findings This study sorted out 25 improvement ideas according to their importance assessed by the PLM system users. The top five ideas are improving data consistency, error minimization, fast system response time, enhancing user recognition, and business process improvement. The support group puts higher importance than the general user group in data consistency, fast system response time, enhancing user recognition, business process improvement, dedicated team for data consistency, continuous support from management, hardware performance upgrade, output linkage to other systems, and shortening problem solving duration. The largest company group attaches significantly higher weights than the smallest company group to data consistency, error minimization, fast system response time, business process improvement, dedicated team for data consistency, security with proper access management, output linkage to other systems, and better user interface.

A Study On the Clusters In the Electronic Industry Using Social Network Analysis (사회적 네트워크 분석을 이용한 전자산업 클러스터 연구)

  • Jung, Jaeheon
    • The Journal of the Korea Contents Association
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    • v.19 no.5
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    • pp.48-63
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    • 2019
  • We tried new analysis including social network analysis(SNA) on the transaction network centered on electronic companies using more than 50 thousand company transaction data obtained from Korean enterprise data (KED) for the year of 2015. We found 97 clusters having more than 10 firms and remarkable 13 clusters having more than 90% sales of the electronic industry in Korea. Clusters are the groups of companies having most of their transactions in the clusters they belong to. We found 5 clusters have 83% of sales in the electronic industry. Most of clusters have main single firms having most of the sales in each clusters except a few clusters. However, we found a few firms to have high rear production linkage effect and found the firms with high linkage effect specially for the small and medium size enterprise (SME). The companies with high production linkage (specially on SMEs) should be managed in terms of (SME) growth policy. The last firm group consisting of the small clusters with less than 10 firms has high employment coefficients. The clusters or company having high production linkage effect on this last firm group should be noted in the terms of employment policy. We also note that there exist the firms with the high value of betweenness coefficients meaning high potential of technology development. They should be managed carefully in terms of technology development policy.