• IMMUNE NETWORK
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• v.1 no.2
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• pp.104-108
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• 2001

Aging is a senescence and defined as a normal physiologic and structural alterations in almost all organ systems with age. As Leonard Hayflick, one of the first gerontologists to propose a theory of biologic aging, indicated that a theory of aging or longevity satisfies the changes of above conditions to be universal, progressive, intrinsic and deleterious. Although a number of theories have been proposed, it is now clear that cell aging (cell senescence) is multifactorial. No single mechanism can account for the many varied manifestations of biological aging. Many theories have been proposed in attempt to understand and explain the process of aging. Aging is effected in individual by genetic factors, diet, social conditions, and the occurrence of age-related diseases as diabetes, hypertension, and arthritis. It involves an endogenous molecular program of cellular senescence as well as continuous exposure throughout life to adverse exogenous influences, leading to progressive infringement on the cell's survivability so called wear and tear. So we could say the basic mechanism of aging depends on the irreversible and universal processes at cellular and molecular level. The immediate cause of these changes is probably an interference in the function of cell's macromolecules-DNA, RNA, and cell proteins-and in the flow of information between these macromolecules. The crucial questions, unanswered at present, concerns what causes these changes in truth. Common theories of aging are able to classify as followings for the easy comprehension. 1. Biological, 1) molecular theories - a. error theory, b. programmed aging theory, c. somatic mutation theory, d. transcription theory, e. run-out-of program theory, 2) cellular theories - a. wear and tear theory, b. cross-link theory, c. clinker theory, d. free radical theory, e. waste product theory, 3) system level theory-a. immunologic/autoimmune theory, 4) others - a. telomere theory, b. rate of living theory, c. stress theory, etc. Prevention of aging is theoretically depending on the cause or theory of aging. However no single theory is available and no definite method of delaying the aging process is possible by this moment. The most popular action is anti-oxidant therapy using vitamin E and C, melatonin and DHEA, etc. Another proposal for the reverse of life-span is TCP-17 and IL-16 administration from the mouse bone marrow B cell line study for the immunoglobulin VDJ rearrangement with RAG-1 and RAG-2. Recently conclusional suggestion for the extending of maximum life-span thought to be the calory restriction.

• Journal of dental hygiene science
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• v.3 no.2
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• pp.77-82
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• 2003

The purpose of this study was to examine the characteristics of dental homepages in korea to discuss how they could be improved better. The findings of this study could be described as below : First, dental homepage should include differentiated, specialized content and features. Second, the use of three-dimensional image or multimedia would contribute to increasing people's understanding of dental treatment or general dental information and elevating the effectiveness of dental publicity activities. Third, the want ad and order system used by the business sector or hospital would serve to multiply the management efficiency of dental institutions. Fourth, dental hospitals and clinics that belong to the same network or franchise need to make publicity banner for feasible mutual link, and the use of the same homepage design or common logo would be effective for better image and publicity activities. Fifth, it would be convenient to add the map search function or inquiry system. Seventh, if multiple types of services, such as entertainment or game, are prepared, it would be possible for dental institutions to project a better image and to induce visitors to hit the sites again.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.11
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• pp.44-52
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• 1998

In this paper, we proposed a node architecture and cell routing strategies for ATM applications in WDM multihop networks. The proposed node architecture employs the optical delay loop for storing the cell which is failed in out-link contention. This optical delay loop allows the delay of one cell without the electro-optic conversion. Therefore, we can get the advantages of S&F(Store-and-Forward) routing in Deflection-based all-optical networks. To support the ATM applications efficiently. we considered the transmission priority of ATM cell so that high priority cell can be transmitted with lower loss and shorter delay than low priority one. Two kinds of routing strategies are designed for this architecture: Scheme-Ⅰand Scheme-Ⅱ. Scheme-Ⅰapplies S&F routing to high cell and Deflection routing to low cell, i.e., high cells are routed along the shortest path based on S&F routing, but low cells are deflected or lost. Schem-Ⅱ is similar to Scheme-Ⅰexcept that low cells can occupy the optical loop if it is available. This Scheme-Ⅱ increases the utilization of network resources without decreasing the throughput of high cell by reducing the low cell loss rate when traffic load is low. Simulation results show that our routing strategies have better performance than conventional ones under non-uniform traffic as well as uniform traffic.

• The Journal of Society for e-Business Studies
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• v.20 no.4
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• pp.193-208
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• 2015

In knowledge based society, information technology (IT) has been playing a key role in economic growth. In recent years, it is surprisingly notable that the source of value creation moved from hardware to software in IT industry. Especially, among many kinds of software products, the economic potential of open source was realized by many government agencies. Open source means software codes made by voluntary and open participation of worldwide IT developers, and many policies to promote open source activities were implemented for the purpose of fast growth in IT industry. But in many cases, especially in Korea, the policies promoting open source industry and its ecosystem were not considered successful. Therefore, this study provides the practical reasons for the low performance of Korean open source industry and suggests the pragmatic requisites for effective open source policy. For this purpose, this study applies soft system model (SSM) which is frequently used in academy and industry as a methodology for problem-solving and we link the problems with corresponding policy solutions based on SSM. Given concerns which Korean open source faces now, this study suggests needs for the three different kinds of government policies promoting multiple dimensions of industry: research and development (R&D)-side, supply-side, and computing environment-side. The implications suggested by this research will contribute to implement the practical policy solutions to boost open source industry in Korea.

• The Journal of Society for e-Business Studies
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• v.20 no.1
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• pp.183-199
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• 2015

Due to the Four Major Rivers Restoration Project, Nakdong River Estuary Barrage's designed flood quantity has been largely increased, and this has caused to construct several drainage gates at the right side of Eulsukdo island to secure the safety of downstream river area. For successful functioning of Nakdong River Estuary Barrage, such as flood control, disaster prevention, and the securing of sufficient water capacity, drainage gates at the both sides of island have to operate systematically and reliably. To manage this under restricted personnel and resources, we have implemented the IOS (Integrated Operation System) by integrating previous facilities and resources via information and communication technologies. The IOS has been designed to have higher availability and fault tolerance to function continuously even with the partial system's failure under the emergency situation like flood. Operators can use the system easily and acknowledge alarms of facilities through its IWS (Integrated Warning System) earlier. Preparing for Integrated Water Resources Management and Smart Water Grid, the architecture of IOS conformed to open system standards which will be helpful to link with the other systems easily.

• Journal of the Korean Society of Food Science and Nutrition
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• v.24 no.5
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• pp.816-828
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• 1995

During the industrial preparation and the storage of foods, the side chain of some protein-bound amino acids can react chemically each other or with other molecules present in the food. The following reactions have been described : destruction of amino acids, racemization, protein-protein interactions, reactions of proteins with reducing sugars, oxidizing agents, or polyphenols. Apart from total destruction, the main reacitons are the forming of Maillard reactions products(e.g. fructoselysine) and the crosslinking with other amino acids in the same or in another protein molecule(e.g. lysinoalanine). The most often involved amino acid is lysine because of its free functional ${\varepsilon}-amino$ acid group. Generally derivatives of amino acids or crosslinks in polypeptides influence the bioavailability and the overall digestibility of the protein. This work reviews the technological, analytical, nutritional, and physiological problems related to the formation of fructoselysine and lysinolalnine in human foods, and evaluates the possible health risk for humans. A summary of the available information is of help in considering whether or not the presence of fructoselysine/lysinoalanine in foods represents a danger to man. The reduction in protein quality through these reactions is not a problem for the general population, but it is extremely important in infant foods, since infants are often nourished with a limited number of food product(e.g. formular foods) which are sensitive to the Mailard reaction.

• Journal of Science Education
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• v.36 no.2
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• pp.354-368
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• 2012

The purpose of this study was to explore the direction of application and quality management plan of science curriculum of elementary and middle school according to the 2009 revised curriculum. In order to do this, nationwide survey was administered. The subject was 126 elementary school teachers and 88 middle school science teachers. It was founded that teachers had negative opinion on the introduction of the grade cluster system. They considered that it was appropriate to link the contents of Science subject with Practical Arts(Technology Home Economics) subject by similar topic. Science classes were implemented without changing the number of class hours in most schools. They recognized the necessity of differentiated instruction in science classes, but they seldom applied the differentiated instruction. And they suggested that the teaching-learning materials, evaluation materials and contents be provided to apply the STEAM. This study designates the following strategic supports for the effective implementation of 2009 revised science curriculum; 1) the science teachers training program to provide useful information for understanding and teaching the 2009 revised science curriculum, 2) the teachers' community in the school, 3) the development and provision of the feasible STEAM plans.

• Journal of Korean Society of Transportation
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• v.17 no.2
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• pp.55-68
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• 1999

Many ITS services require map databases in digital form to meet desired needs. Due to the dynamic nature of ITS and the sheer diversity of applications, the design and development of spatial databases to meet those needs pose a major challenge to both the public and private sectors. This challenge is further complicated by the necessity to transfer locationally referenced information between different kinds of databases and spatial data handling systems so that ITS products will work seamlessly across the region and nation. The Purpose of this paper is to develop the framework-models commonly to reference locations in the various applications and systems-the ITS Map Datum and LRS(Location Referencing System). The ITS Map Datum consists of the around control points which are the prime intersections (nodes) of the nationwide road network In this study, the major points have been determined along wish link-node modeling procedure. LRS, defined as a system for determining the position (location) of an entity relative to other entities or to some external frame of reference, has also been set up using CSOM type method. The method has been implemented using ArcView GIS software over the Kangnam and Seocho districts in the city of Seoul, showing that the implemented LRS scheme can be used successfully elsewhere. With the proper advent of the K.ITS architecture and services, the procedure can be used to improve the data sharing and to inter operate among systems, enhancing the efficiency both in terms of money and time.

• The KIPS Transactions:PartA
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• v.11A no.3
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• pp.189-198
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• 2004

We consider the fault hamiltonian properties of m ${\times}$ n meshes with two wraparound links on the first row and the last row, denoted by M$_2$(m,n), (m$\geq$2, n$\geq$3). M$_2$(m,n), which is bipartite, with a single faulty link has a fault-free path of length mn-l(mn-2) between arbitrary two nodes if they both belong to the different(same) partite set. Compared with the previous works of P$_{m}$ ${\times}$C$_{n}$ , it also has these hamiltonian properties. Our result show that two additional wraparound links are sufficient for an m${\times}$n mesh to have such properties rather than m wraparound links. Also, M$_2$(m,n) is a spanning subgraph of many interconnection networks such as multidimensional meshes, recursive circulants, hypercubes, double loop networks, and k-ary n-cubcs. Thus, our results can be applied to discover fault-hamiltonicity of such interconnection networks. By applying hamiltonian properties of M$_2$(m,n) to 3-dimensional meshes, recursive circulants, and hypercubes, we obtain fault hamiltonian properties of these networks.

• The KIPS Transactions:PartC
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• v.15C no.5
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• pp.399-408
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• 2008

Mobile WiMAX provides wireless broadband services for data communication based on IP protocol. The limitation of physical bandwidth in the radio links may cause performance degradation in providing wireless broadband services in WIMAX. To enhance the efficiency of the radio link utilization, Payload Header Suppression (PHS) is defined as an optional header compression mechanism for mobile WiMAX. It has, however, a very limited compression capability since it has very restrictive compression fields. In this paper, hence, we assumed the application of Robust Header Compression (ROHC), a header compression scheme proposed for links characterized by high bit error ratios, long round-trip times (RTT), and scarce resource, to Mobile WiMAX, and studied its performance. Previous studies on ROHC performance merely focused on the impact of high bit error rate. However, bit error is virtually transparent to ROHC in the wireless systems like WiMAX, since the MAC provides the bit error checking function. In order to evaluate the performance of ROHC in the Mobile WiMAX environments, therefore, we evaluated the performance of ROHC with respect to the packet losses instead of bit error. We investigated the impact of the ROHC parameters that are recommended for the implementation in the ROHC and compared the performance of ROHC with PHS.