• Korean Journal of Clinical Laboratory Science
• /
• v.36 no.1
• /
• pp.13-18
• /
• 2004

This study was designed to establish working range for reoportable range in own laboratory in order to cover the upper and lower limits of the range in test method. We experimented ten times during 10 days for setting of reportable range with between run for method evaluation. It is generally assumed that the analytical method produces a linear response and that the test results between those upper and lower limits are then reportable. CLIA recommends that laboratories verify the reportable range of all moderate and high complexity tests. The Clinical Laboratory Improvement Amendments(CLIA) and Laboratory Accreditation Program of the Korean Society for Laboratory Medicine states reportable range is only required for "modified" moderately complex tests. Linearity requirements have been eliminated from the CLIA regulations and from others accreditation agencies, many inspectors continue to feel that linearity studies are a part of good lab practice and should be encouraged. It is important to assess the useful reportable range of a laboratory method, i.e., the lowest and highest test results that are reliable and can be reported. Manufacturers make claims for the reportable range of their methods by stating the upper and lower limits of the range. Instrument manufacturers state an operating range and a reportable range. The commercial linearity material can be used to verify this range, if it adequately covers the stated linear interval. CLIA requirements for quality control, must demonstrate that, prior to reporting patient test results, it can obtain the performance specifications for accuracy, precision, and reportable range of patient test results, comparable to those established by the manufacturer. If applicable, the laboratory must also verify the reportable range of patient test results. The reportable range of patient test results is the range of test result values over which the laboratory can establish or verify the accuracy of the instrument, kit or test system measurement response. We need to define the usable reportable range of the method so that the experiments can be properly planned and valid data can be collected. The reportable range is usually defined as the range where the analytical response of the method is linear with respect to the concentration of the analyte being measured. In conclusion, experimental results on reportable range using concentrated control sample and zero calibrators covering from highest to lowest range were salicylate $8.8{\mu}g/dL$, phenytoin $0.67{\mu}g/dL$, phenobarbital $1.53{\mu}g/dL$, primidone $0.16{\mu}g/dL$, theophylline $0.2{\mu}g/dL$, vancomycine $1.3{\mu}g/dL$, valproic acid $3.2{\mu}g/dL$, digitoxin 0.17ng/dL, carbamazepine $0.36{\mu}g/dL$ and acetaminophen $0.7{\mu}g/dL$ at minimum level and salicylate $969.9{\mu}g/dL$, phenytoin $38.1{\mu}g/dL$, phenobarbital $60.4{\mu}g/dL$, primidone $24.57{\mu}g/dL$, theophylline $39.2{\mu}g/dL$, vancomycine $83.65{\mu}g/dL$, valproic acid $147.96{\mu}g/dL$, digitoxin 5.04ng/dL, carbamazepine $19.76{\mu}g/dL$, acetaminophen $300.92{\mu}g/dL$ at maximum level.

• Polymer(Korea)
• /
• v.32 no.4
• /
• pp.340-346
• /
• 2008

The aim of this study is to understand the effect of structure on the dispersion of both CNT and GNF in the phase of synthesized polyurethanes matrix. Various CNT/PU and GNF/PU composite films were prepared. Polyurethane having a different hard segment was blended with both CNT and GNF. PU having HDI as hard segment showed good dispersion with both CNT and GNF because of their linear structural character and molecular kinesis while PU having aromatic ring showed poor dispersion with those due to their structural complexity. Structural effect also induced the increase of its electro conductivity. The PU/CNT composite showed a bad dispersion (because of phase separation between PU matrix and CNT) but good electro conductivity at its surface (because CNT was collected on the surface of composite film due to low density of CNT). PU/CNT and PU/GNF composite films have quite low normalized sheet resistance value compared with silver/PU nanocomposite film because the fiber type filler could have much more contact points than that of sphere shaped silver particles have.

• Economic and Environmental Geology
• /
• v.6 no.4
• /
• pp.201-216
• /
• 1973

Being believed thus far to be distributed in the wide areas in the vicinity of Seoul, the capital city of Korea, the Yonchon System in its type locality in Yonchon-gun from which the name derived was never previously traced down or correlated to the Precambrian metamorphic complex in Seoul area where the present study was carried out. Due to in accessibility to Yonchon area, the writer also could not trace the system down to the area studied so as to correlate them. The present study endeavored to differentiate general stratigraphy and interprete the structure of the metamorphic complex in the area. In spite of the complexity of structure and rapid changes in lithofacies of the complex, it was succeeded to find out the key bed by which the stratigraphy and structure of the area could be straightened out. The keybeds were the Buchon limestone bed in the western parts of the area; Daisongri quartzite bed cropped out in the southeastern area; Jangrak quartzite bed scattered in the several localities in the northwest, southwest, and eastern parts of the area; and Earn quartzite bed isolated in the eastern part of the area. These keybeds together with the broad regional structure made it possible to differentiated the Precambrian rocks in ascending order into the Kyonggi metamorphic complex, Jangrak group and Chunsung group which are in clinounconformable relation, and the first complex were again separated in ascending order into Buchon, Sihung, and Yangpyong metermorphic groups. Althcugh it has being vaguely called as the Yonchon system thus far, the Kyonggi metamorphic complex have never been studied before. The complex might, however, belong to early to early-middle Precambrian age. The Jangrak and Chunsung group were correlated to the Sangwon system in North Korea by the writer (1972), but it became apparent that the rocks of the groups have different lithology and highly metamorphosd than those of the Sangwon system which has thick sequence of limestone and slightly metamorphosed. Being deposited in the margin of the basin, it is natural that the groups poccess terrestrial sediments rather than limestone, yet no explanation is at hand as to what was the cause of bringing such difference in grade of metamorphism. Thus the writer attempted to correlate the both groups to those of pre-Sangwon and post-Yonchon which might be middle to early-late Precambrian time. Judging from difference in grade of deformation and unconformity between the Kyonggi metamorphic complex, Jangrak group, and Chunsung group, three stages of orogeny were established: the Kyonggi, Jangrak orogenies, and Chunsung disturbance toward younger age. It is rather astonishing to point out that the structure of these Precambrian formations. was not effected by Daebo orogeny of Jurassic age. The post-tectonic block faulting was accompanied by these orogenies, and in consequence NNE and N-S trending faults were originated. These faulting were intermittented and repeated until Daebo orogeny at which granites intruded along these faults. The manifestation of alignment of these faults is indicated by the parallel and straight linear development of valleys and streams in the Kyonggi Massifland.

• Journal of the Korean Association of Geographic Information Studies
• /
• v.8 no.2
• /
• pp.81-94
• /
• 2005

The purpose of this study is to test the applicability of landscape metrics for quantifying and monitoring the landscape structure in the Geumho River watershed, which has undergone heavy environmental disturbances. Landscape metrics were computed from land cover maps(1985, 1999) for the forest patches. The number of variables were reduced from 12 metrics to 3 factors through factor analysis. These factors accounted for above 91% of the variation in the original metrics. We also determined the relative effects of land development on the changes of forest landscape structure using multiple linear regression analysis. At the forest patches, the conversion of forest to urban areas and agriculture resulted in increased fragmentation. Patch area and patch size decreased. and patch density increased as a result of the conversion of forest to agriculture($R^2=0.696$, p<0.01). The heterogeneity of patch size and complexity of patch shape mainly decreased as a result of the conversion of forest to urban areas($R^2=0.405$, p<0.01). The density of core area and edge showed the tendency increase, but there was no relationship with the conversion of forest to urban area and agriculture The future research will be needed to analyze correlations between landscape structures and specific environmental and socioeconomic landscape functions.

• Journal of the Korean Society for Nondestructive Testing
• /
• v.36 no.5
• /
• pp.370-376
• /
• 2016

Corrosion on the surface of a structure can generate cracks or cause walls to thin. This can lead to fracturing, which can eventually lead to fatalities and property loss. In an effort to prevent this, laser imaging technology has been used over the last ten years to detect thin-plate structure, or relatively thin piping. The most common laser imaging was used to develop a new technology for inspecting and imaging a desired area in order to scan various structures for thin-plate structure and thin piping. However, this method builds images by measuring waves reflected from defects, and subsequently has a considerable time delay of a few milliseconds at each scanning point. In addition, the complexity of the system is high, due to additional required components, such as laser-focusing parts. This paper proposes a laser imaging method with an increased scanning speed, based on excitation and the measurement of standing waves in structures. The wavenumber of standing waves changes at sections with a geometrical discontinuity, such as thickness. Therefore, it is possible to detect defects in a structure by generating standing waves with a single frequency and scanning the waves at each point by with the laser scanning system. The proposed technique is demonstrated on a wall-thinned plate with a linear thickness variation.

• Journal of Korean Society of Transportation
• /
• v.30 no.4
• /
• pp.21-32
• /
• 2012

Exclusive bus lane (EBL) is typically located in the roadway median, and is accessed by weaving across the GPLs(general purpose lanes) before entering from the left lane of the GPLs. To maximize the potential for successful EBL operations, a critical design issue that requires special attention is the length of bus weaving section before entering EBL. The process of developing guidelines for the length of bus weaving section can be supported by a sensitivity analysis of performance measure (safety) with respect to the bus weaving distance. However, field data are difficult to obtain due to inherent complexity in creating performance measure (safety) samples under various interesting flows and bus weaving distance that are keys to research success. In this paper, VISSIM simulation is applied to simulate the operation of roadway weaving areas with EBL, and based on vehicle trajectory data from microscopic traffic simulation models, the Surrogate Safety Assessment Model (SSAM) computes the number of surrogate conflicts (or degree of safety) with respect to the bus weaving distance. Then, a multiple linear regression (MLR) model using safety data (number of surrogate conflicts) is developed. Finally, guidelines for bus weaving distance are established based on the developed MLR. Developed guidelines explicitly indicate that a longer bus weaving distance is required to maintain desired safety as weaving volume increases.

• Quality Improvement in Health Care
• /
• v.7 no.2
• /
• pp.230-242
• /
• 2000

Background : The measuring instruments for customer satisfaction in hospitals are often composed of some dimensions reflecting the conceptive complexity of them. Then, overall satisfaction would be expected to be equal the 'weighted' sum of scores by dimensions because the importance rated by customers may be different across the dimensions. But the issue of how to weight the dimensions with importance is not yet solved. We examined 3 sets of weighting methods as to make effect on predictive power against overall satisfaction. Methods : We conducted a survey included 483 subjects who had visited or admitted to a university hospital, using the short form questionnaire being developed by The Korean Society of Quality Assurance in Health Care for out-patient and in-patient. By using a multiple linear regression model, we compared among changes of explanatory powers against overall satisfaction as dependent variable after weighting 4 dimensions of the survey questionnaire as independent variables with importance scores of dimensions perceived by consumers. And we compared the feasibility of each weighting, methods by checking missing cases. Results : There were no weighting methods increasing the explanatory power after applying them. The method of absolute scoring was found higher explanatory-power than others, but this finding had no statistical significance. Regarding the number of missing value, method of absolutely scoring had the least cases. Conclusion : Our findings suggested that weighting the dimensions with importance might have little significance in the cases of scales having items highly correlated, such as consumers' satisfaction. Though asking with items to be answered absolutely, customers might be rating relatively in some degree and this method produced least missing cases. Considering these points, in the cases when weighting the dimensions with importance would be required, we suggest that weighting method by absolute scoring might be better than others.

• The Journal of Korean Society for Radiation Therapy
• /
• v.19 no.1
• /
• pp.7-17
• /
• 2007

Purpose: As increasing complexity of modern radiotherapy technique, more developing dosimetry is required. Polymer gel dosimeters offer a wide range of potential applications with high resolution and assured quality in the thee-dimensional verification of complex dose distribution such as intensity-modulated radiotherapy (IMRT). The purpose of this study is to find the most sensitive and suitable gel as a dosimeter by varying its composition ratio and its condition such as temperature during manufacturing. Materials and Methods: Each polymer gel with various ratio of composition was irradiated with the same amount of photon beam accordingly. Various polymer gels were analyzed and compared using a dedicated software written in visual C++ which converts TE images to R2 map images. Their sensitivities to the photon beam depending on their composition ratio were investigated. Results: There is no dependence on beam energy nor dose rate, and calibration curve is linear. Conclusion: The polymer gel dosimeter developed by using anti-oxidant in this study proved to be suitable for dosimetry.

• Journal of KIISE:Databases
• /
• v.34 no.6
• /
• pp.483-492
• /
• 2007

Time series of conventional prediction techniques uses the model which is generated from the training step. This model is applied to new input data without any change. If this model is applied directly to stream data, the rate of prediction accuracy will be decreased. This paper proposes an stream data prediction technique using sliding window and regression. This technique considers the characteristic of time series which may be changed over time. It is composed of two steps. The first step executes a fractional process for applying input data to the regression model. The second step updates the model by using its information as new data. Additionally, the model is maintained by only recent data in a queue. This approach has the following two advantages. It maintains the minimum information of the model by using a matrix, so space complexity is reduced. Moreover, it prevents the increment of error rate by updating the model over time. Accuracy rate of the proposed method is measured by RME(Relative Mean Error) and RMSE(Root Mean Square Error). The results of stream data prediction experiment are performed by the proposed technique IMQR(Incremental Multiple Quadratic Regression) is more efficient than those of MLR(Multiple Linear Regression) and SVR(Support Vector Regression).

• Journal of the Korean Society of Safety
• /
• v.35 no.4
• /
• pp.64-73
• /
• 2020

As Korean government and safety-related organizations make continuous efforts to reduce the number of industrial accidents, accident rate has steadily declined since 2010, thereby recording 0.48% in 2017. However, the number of fatalities due to industrial accidents was 1,987 in 2017, which means that more efforts should be made to reduce the number of industrial accidents. As an essential activity for enhancing the system safety, accident analysis can be effectively used for reducing the number of industrial accidents. Accident analysis aims to understand the process of an accident scenario and to identify the plausible causes of the accident. Accident analysis offers useful information for developing measures for preventing the recurrence of an accident or its similar accidents. However, it seems that the current practice of accident analysis in Korean manufacturing companies takes a simplistic accident model, which is based on a linear and deterministic cause-effect relation. Considering the actual complexities underlying accidents, this would be problematic; it could be more significant in the case of human error-related accidents. Accordingly, it is necessary to use a more elaborated accident model for addressing the complexity and nature of human-error related accidents more systematically. Regarding this, HFACS(Human Factors Analysis and Classification System) can be a viable accident analysis method. It is based on the Swiss cheese model and offers a range of causal factors of a human error-related accident, some of which can be judged as the plausible causes of an accident. HFACS has been widely used in several work domains(e.g. aviation and rail industry) and can be effectively used in Korean industries. However, as HFACS was originally developed in aviation industry, the taxonomy of causal factors may not be easily applied to accidents in Korean industries, particularly manufacturing companies. In addition, the typical characteristics of Korean industries need to be reflected as well. With this issue in mind, we developed HFACS-K as a method for analyzing accidents happening in Korean industries. This paper reports the process of developing HFACS-K, the structure and contents of HFACS-K, and a case study for demonstrating its usefulness.