• Title/Summary/Keyword: Line profile

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Effects of Triterpenoids from Luvunga scandens on Cytotoxic, Cell Cycle Arrest and Gene Expressions in MCF-7 Cells

  • Taher, Muhammad;Al-Zikri, Putri Nur Hidayah;Susanti, Deny;Arief Ichwan, Solachuddin Jauhari;Rezali, Mohamad Fazlin
    • Natural Product Sciences
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    • v.22 no.4
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    • pp.293-298
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    • 2016
  • Plant-derived triterpenoids commonly possesses biological properties such as anti-inflammatory, antimicrobial, anti-viral and anti-cancer. Luvunga scandens is one of the plant that produced triterpenoids. The aims of the study was to analyze cell cycle profile and to determine the expression of p53 unregulated modulator of apoptosis (PUMA), caspase-8 and caspase-9 genes at mRNA level in MCF-7 cell line treated with two triterpenoids, flindissol (1) and 3-oxotirucalla-7,24-dien-21-oic-acid (2) isolated from L. scandens. The compounds were tested for cell cycle analysis using flow cytometer and mRNA expression level using quantitative RT-PCR. The number of MCF-7 cells population which distributed in Sub G1 phase after treated with compound 1 and 2 were 7.7 and 9.3% respectively. The evaluation of the expression of genes showed that both compounds exhibited high level of expression of PUMA, caspase-8 and caspase-9 as normalized to ${\beta}-actin$ via activation of those genes. In summary, the isolated compounds of L. scandens plant showed promising anticancer properties in MCF-7 cell lines.

An Analysis of Unsteady 2-D Heat Transfer of the Thermal Stratification Flow inside Horizontal Pipe with Electrical Heat Tracing (Heat Tracing이 있는 수평배관 내부 열성층 유동의 비정상 2차원 열전달 해석)

  • 정일석;송우영
    • Journal of Energy Engineering
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    • v.6 no.2
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    • pp.119-128
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    • 1997
  • A method to mitigate the thermal stratification flow of a horizontal pipe line is proposed by heating external bottom of the pipe with electrical heat tracing. Unsteady two dimensional model has been used to numerically investigate an effect of the external heating on the thermal stratification flow. The dimensionless governing equations are solved by using the control volume formulation and SIMPLE algorithm. Temperature distribution, streamline profile and Nusselt number distributions are analyzed under heating conditions. The numerical results of this study show that the maximum dimensionless temperature difference between hot and cold sections of the inner wall of pipe is 0.424 at dimensionless time of 1,500 and the thermal stratification phenomenon disappears at about dimensionless time of 9,000.

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Visual Perception of Garment Surface Appearance

  • Fan, Jintu;Liu, Fu
    • Science of Emotion and Sensibility
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    • v.5 no.3
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    • pp.1-10
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    • 2002
  • This paper concerns with the relationship between the visual perception of the degree of pucker or wrinkles of garment surfaces and the geometrical parameters of surfaces. In this study, four potentially relevant parameters of the surface profile are considered, namely, the variance ($\sigma$$^2$), the cutting frequency (F$\_$c/), the effective disparity curvature (D$\_$ce/) (Defined as the average disparity curvature of the wrinkled surface over the eyeball distance of the observer) and the frequency component of the disparity curvature ( D$\_$cf/). Based on the experiments using garment seams having varying degree of pucker (i.e. the wrinkles along a seam line), it was found that, while the logarithm of each of these four parameters has a strong linear relationship with the visually perceived degree of wrinkles, following the Web-Fetchner Law, the effective disparity curvature ( D$\_$ce/) and the frequency component of the disparity curvature (D$\_$cf/) appeared to have stronger relationships with the visual perception. This finding is in agreement with the suggestion by Rogers '||'&'||' Cagenello that human visual system may compute the disparity curvature in discriminating curved surfaces. It also suggested an objective method of measuring the degree of surface wrinkles.

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Galloping analysis of stranded electricity conductors in skew winds

  • Macdonald, J.H.G.;Griffiths, P.J.;Curry, B.P.
    • Wind and Structures
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    • v.11 no.4
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    • pp.303-321
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    • 2008
  • When first commissioned, the 1.6 km span 275kV Severn Crossing Conductor experienced large amplitude vibrations in certain wind conditions, but without ice or rain, leading to flashover between the conductor phases. Wind tunnel tests undertaken at the time identified a major factor was the lift generated in the critical Reynolds number range in skew winds. Despite this insight, and although a practical solution was found by wrapping the cable to change the aerodynamic profile, there remained some uncertainty as to the detailed excitation mechanism. Recent work to address the problem of dry inclined cable galloping on cable-stayed bridges has led to a generalised quasi-steady galloping formulation, including effects of the 3D geometry and changes in the static force coefficients in the critical Reynolds number range. This generalised formulation has been applied to the case of the Severn Crossing Conductor, using data of the static drag and lift coefficients on a section of the stranded cable, from the original wind tunnel tests. Time history analysis has then been used to calculate the amplitudes of steady state vibrations for comparison with the full scale observations. Good agreement has been obtained between the analysis and the site observations, giving increased confidence in the applicability of the generalised galloping formulation and providing insight into the mechanism of galloping of yawed and stranded cables. Application to other cable geometries is also discussed.

The Study on Volumetric Transition Polymer Gel (체적상전이고분자 겔에 관한 연구)

  • 김정곤
    • Journal of the Korean Graphic Arts Communication Society
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    • v.14 no.1
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    • pp.47-54
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    • 1996
  • Deuterium NMR studies have been carried out for two kinds of main- chain dimer liquid crystals $\alpha$.$\omega$-bis[(4,4`-cyanobipheny0oxy] alkane (CBA-n, n=9,100.The H-NMR spectra were recorded on a JEOP JNM-GSX-500 spectrometer by using deuterium labelled CBA-n at various temperatures. The RIS analysis of the NMR spectra was performed so as to elucidate the conformational characteristics of the spacer in the nematic phase. Following the previous treatment, the single-ordering-matrix model was adopted, in which the molecular axis was defined parallel to the line connecting the centers of the terminal mesogenic cores. Conformer fractions of the spacer were estimated by simulation so as to reproduce the observed NMR profile. The conformational entropy changes at both CN and NI interphases were estimated on the basis of the nematic conformations taken from the conformation map as well as those derived from the simulation. In these calculations the spacer was assumed th by in the all-trans conformation and in the random coil stats in the crystal and isotropic phases respectively. The esimated conformational entropy change values were then compared with the corresponding constant-volume entropies obtained from PVT measurements. The correspondence between both entropy values was found to be quite good in consideration of the uncertainties involved in both experiment and calculations.

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The study on the dry etching characteristics of $CeO_2$ thin films ($CeO_2$ 박막의 건식 식각 특성 연구)

  • Oh, Chang-Seck;Kim, Chang-Il
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.05b
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    • pp.84-87
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    • 2001
  • In this study, $CeO_2$ thin films were etched with a $CF_4/Ar$ gas combination in inductively coupled plasma (ICP), The maximum etch rate of $CeO_2$ thin films is $270{\AA}/min$under $CF_4/(CF_4+Ar)$ of 0.2, 600 W/-200 V, 15 mTorr, and $25^{\circ}C$. The selectivities of $CeO_2$ to PR and SBT are 0.21, 0.25. respectively. The surface reaction of the etched $CeO_2$ thin films was investigated with x-ray photoelectron spectroscopy (XPS). There is a chemical reaction between Ce and F, Compounds such as $Ce-F_x$ are remains on the surface of $CeO_2$ thin films. Those products can be removed by Ar ion bombardment effect, The results of secondary ion mass spectrometer (SIMS) were equal to these of XPS. Scanning electron microscopy (SEM) was used to examine etched profiles of $Ce-F_x$ thin films. The etch profile of over-etched $CeO_2$ films with the $0.5 {\mu}m$ line was approximately $65^{\circ}$.

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THE DEVELOPMENT OF THE NARROW GAP MULTI-PASS WELDING SYSTEM USING LASER VISION SYSTEM

  • Park, Hee-Chang;Park, Young-Jo;Song, Keun-Ho;Lee, Jae-Woong;Jung, Yung-Hwa;Luc Didier
    • Proceedings of the KWS Conference
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    • 2002.10a
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    • pp.706-713
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    • 2002
  • In the multi-pass welding of pressure vessels or ships, the mechanical touch sensor system is generally used together with a manipulator to measure the gap and depth of the narrow gap to perform seam tracking. Unfortunately, such mechanical touch sensors may commit measuring errors caused by the eterioration of the measuring device. An automation system of narrow gap multi-pass welding using a laser vision system which can track the seam line of narrow gap and which can control welding power has been developed. The joint profile of the narrow gap, with 250mm depth and 28mm width, can be captured by laser vision camera. The image is then processed for defining tracking positions of the torch during welding. Then, the real-time correction of lateral and vertical position of the torch can be done by the laser vision system. The adaptive control of welding conditions like welding Currents and welding speeds, can also be performed by the laser vision system, which cannot be done by conventional mechanical touch systems. The developed automation system will be adopted to reduce the idle time of welders, which happens frequently in conventional long welding processes, and to improve the reliability of the weld quality as well.

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Identification of Radiation-Resistant Bacterium Isolated from Dried Laver (Porphyra tenera) (김으로부터 분리한 방사선 저항성 세균)

  • Ahn, Hyun-Joo;Yook, Hong-Sun;Kim, Dong-Ho;Kim, Sung;Byun, Myung-Woo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.1
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    • pp.193-195
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    • 2001
  • A radiation-resistant bacterium was isolated from gamma irradiated dried laver (Porphyra tenera) and its microbiological characteristics were examined. As a result of resistance test to gamma irradiation, the isolate was survived $10^{3}$ CFU/mL even at 30 kGy and significant shoulder line zone was shown until 20 kGy. The $D_{10}$ value was 11.27 kGy. The isolate was gram-positive, non-motile coccus and catalase-positive. n culture, the red-pigmented smooth colony was observed. The biochemical test in API (analytical profile index) system showed that the isolate fermented glucose and fructose as the carbon source. Therefore, a radiation-resistant bacterium isolated from laver was potentially identified as Micrococcus roseus sp.

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Evaluation of Bond Strength in cp-Ti and Non-precious Metal-Ceramic System Using a Gold Bonding Agent (티타늄과 비귀금속 합금에 중간층으로 적용한 Au bonding agent의 금속-도재 결합에 대한 평가)

  • Lee, Jung-Hwan;Ahn, Jae-Seok
    • Journal of Technologic Dentistry
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    • v.31 no.4
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    • pp.15-23
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    • 2009
  • The aim of this study was to evaluate the bond strength of using a Au bonding agent applied on cp-Ti and nonprecious metal-gold-ceramic system. Metallic frameworks(diameter: 5mm, height: 20mm)(N=56, n=7per group) cast in Ni-Cr alloy, Co-Cr alloy and cp-Ti were obtained using acrylic templates and airborne particle abraded with $110{\mu}m$ aluminum oxide. Au bonding agent was applied on wash opaque firing as intermediate layer. SEM and SEM/EDS line profile were performed on the cutting the cross-section of the metal substrate-porcelain with intermediate Au coating. Groups were tested using shear bond strength(SBS) testing at 0.5mm/min. The mean SBS values for the ceramic-Au layer-metal combination were significantly higher than those ceramic-metal combination. While ceramic-Au layer-cp-Ti combinations failed to increase bond strength instead of using a titanium bonding porcelain. The appication of using Au intermediate layer significantly improve the bond strength combination with metal-ceramic system.

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Comparison of Shear Bond Strength of Ceramic Fused to Ni-Cr and Co-Cr Alloy by Heat Treatment (도재용착용 Ni-Cr 합금과 Co-Cr 합금의 열처리에 따른 전단결합강도 비교)

  • Ahn, Jae-Seok;Ko, Eun-Kyung;Joo, Kyu-Ji
    • Journal of Technologic Dentistry
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    • v.33 no.3
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    • pp.185-192
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    • 2011
  • Purpose: This study was to evaluate the shear bond strength of the ceramic fused to Ni-Cr alloy(Bellabond plus) and Co-Cr alloy(Wirobond C) by heat treatment. Methods: Metal specimens were divided into 5 groups for each alloy according to heat treatment conditions prior to porcelain application. Fifteen specimens from each group were subjected to a shear load a universal testing machine using a 0.1mm/min cross-head speed and one specimen from each group was observed with EDX line profile. Results: The diffusion of metal oxide observed far in the specimen heat treated than no heat treated in the opaque layer. The shear bond strength measured highest to BP3(50.50MPa), WC2(50.49MPa) groups and measured lowest from BP1(35.1MPaa), WC1(39.66MPa) groups which were not treated with heat, and there was a significant difference (p<0.05). Conclusion: The shear bond strength of Ni-Cr alloy(Bellabond plus) and Co-Cr alloy(Wirobond C) measured similar 5 groups all.