• 대한기계학회논문집
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• 제9권6호
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• pp.732-742
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• 1985

본 논문에서는 이 2차원 재부착분류(본문에서는 stepped wall jet라 명명함) 유동장을 재부착상류 부분, 재부착점 근방, 재부착 이후의 재발전 벽면분류 지역의 세 영역으로 구분하여 재부착 길이, 평균속도, 벽면정압을 측정하고 on-line에 의한 디지 틀 데이터 처리기법을 이용하여 난류강도, 레이놀즈 전단응력, 속도의 3승적(triple velocity product), integral length scale, Taylor's microscale 등을 실험적으로 구 하여 재부착 상류 부분에서는 자유분류와 비교하고, 재부착 이후에서는 2차원 벽면분 류와 비교하기로 한다.그리하여 초기 교란을 받는 분류가 벽면에 재부착하여 2차원 벽면분류로 재발전되어 가는 과정에 있어서의 평균 유동장과 급격한 변화를 갖는 난류 특성을 상세히 조사하여, 보다 일반적으로 적용될 수 있는 난류모델을 개발함에 있어 서 실험적인 자료를 제공하고자 한다. Fig. 1은 본 실험의 유동장에 대한 개약도를 보여주고 있다.

• 한국산학기술학회:학술대회논문집
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• 한국산학기술학회 2012년도 춘계학술논문집 2부
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• pp.512-516
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• 2012

Recently the Korean government's green energy growth policy has been taken at the national level due to the sufficient supply of renewable energy. Some specific technique should be taken in consideration for the operation of the grid voltage and power quality management. In this case, there may have some chance of operational problems. Typical problems arise when grid-connected solar power produced by Pacific sunshine. The power flow in the reverse direction can create overvoltage on the distribution line and gives value of malfunction on the system. Line voltage and overvoltage adjustment practice can stop these symptoms occurred. Under these circumstances, this paper presents an interconnection test devices for photovoltaic(PV) systems composed of distribution system simulator, PV system simulator and control and monitoring systems using the LabVIEW S/W, and simulates the customer voltage characteristics considering the 3 parameters on the introduction capacity for PV systems, system configuration and Power factor. This paper also proposes a new calculation algorithm for voltage profile to make comparison between calculation values and test device values. The results show that the simulation results for the normal operation characteristics of PV systems which are very practical and effective.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제23권1호
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• pp.7-14
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• 2001

Purpose : The lateral cephalometric Korean norms of the skeletal and pharyngeal dimension were analyzed for the diagnosis of obstructive sleep apnea syndrome(OSAS). Materials and Methods : The lateral cephalometric radiographies were taken in male(n=53) and female(n=50), who had a normal profile, class I occlusion, normal ANB $(0{\sim}4^{\circ})$ and normal Wits $Appraisal(-4{\sim}0mm)$. The X-rays were traced by two oral and maxillofacial surgeons twice. The significant differences between male-female and examiners were tested. Results : The angle of mandibular line to Nasion-Sella line was $31.12^{\circ}/33.79^{\circ}$ (in male/in female, p=0.0018). The lower Gonion angle was $73.74^{\circ}/73.74^{\circ}(p=0.9978)$. The length of the soft palate was 36.93mm/34.35mm(p=0.0002). The pharyngeal airway space was 13.42mm/11.55mm at mandibular plane level(PAS(ML))(p=0.0025). The hyoid was placed inferiorly to mandibular plane 10.18mm/7.72mm(p=0.0051). The results from this study are to be used for the diagnosis of OSAS.

• 대한기계학회논문집A
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• 제34권2호
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• pp.237-243
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• 2010

본 논문은 자동차 변속기의 헬리컬기어 검사 장치에 대한 것이다. 기어 프로파일 전용 검사설비는 시간이 많이 소요되므로 생산라인용으로 적합하지 못하다. 본 논문에서 사용된 마스트기어를 이용하여 생산된 기어와 비교하여 방법은 보다 경제적이며 효율적이다. 본 논문에 사용된 3가지 기어검사 파라미터는 nick, 흔들림(run-out) 및 PCD (pitch circle diameter) 등이다. 기어검사장치의 측정정밀도에 영향을 미치는 요소들에 대해서도 또한 언급되었다. 이 장치는 현재 국내에서 전량 수입되는 기어 생산라인용 설비에 실제적으로 사용될 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3849-3856
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• 2015

Background: Cholangiocarcinoma (CCA), or bile duct cancer, is incurable with a high mortality rate due to a lack of effective early diagnosis and treatment. Identifying cytoplasmic membrane proteins of invasive CCA that facilitate cancer progression would contribute toward the development of novel tumor markers and effective chemotherapy. Materials and Methods: An invasive CCA cell line (KKU-100) was stimulated using TNF-${\alpha}$ and then biotinylated and purified for mass spectrometry analysis. Novel proteins expressed were selected and their mRNAs expression levels were determined by real-time RT-PCR. In addition, the expression of ALCAM was selected for further observation by Western blot analysis, immunofluorescent imaging, and antibody neutralization assay. Results: After comparing the proteomics profile of TNF-${\alpha}$ induced invasive with non-treated control cells, over-expression of seven novel proteins was observed in the cytoplasmic membrane of TNF-${\alpha}$ stimulated CCA cells. Among these, ALCAM is a novel candidate which showed significant higher mRNA- and protein levels. Immunofluorescent assay also supported that ALCAM was expressed on the cell membrane of the cancer, with increasing intensity associated with TNF-${\alpha}$. Conclusions: This study indicated that ALCAM may be a novel protein candidate expressed on cytoplasmic membranes of invasive CCA cells that could be used as a biomarker for development of diagnosis, prognosis, and drug or antibody-based targeted therapies in the future.

• Asian Pacific Journal of Cancer Prevention
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• 제15권18호
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• pp.7673-7677
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• 2014

Background: Patients with long-standing inflammatory bowel disease (IBD) have an increased risk of developing colorectal cancer (CRC). Colon cancer risk in IBD increases with longer duration and greater anatomic extent of colitis, the presence of primary sclerosing cholangitis, family history of CRC and degree of inflammation of the bowel. This study aimed to characterize the histopathological pattern of benign colorectal diseases among Saudi patients and to highlight age and gender variations of lesions as base line data for future studies to investigate the link between benign/IBD and colorectal cancers in the local population. Materials and Methods: The materials consisted of 684 biopsies, reported as benign (excluding malignancies and polyps) at the Department of Pathology, King Fahad Hospital, Madinah, Saudi Arabia from January 2006 to December 2013. Data collected and entered in MS-Excel and were analyzed using SPSS-20. Results: Of 684 colorectal tissues reviewed, 408 specimens (59.6%) were from male patients and 276 specimens (40.4%) were from females giving a male: female ratio of 1.5:1. Age of the patients ranged from 4 to 75 years with a mean of 39.6 years. The most frequent histologic diagnosis was a chronic non specific proctocolitis followed by ulcerative colitis, accounting respectively for 52.6% and 31.7% of all cases. These were followed by Crohn's disease 22 (3.2%), ischemic bowel disease 20 (2.9%), diverticular disease 14 (2%), eosinophilic colitis 12 (1.7%) and solitary rectal ulcer 12 (1.7%). A minority of 21 patients (3.1%) were cases of acute nonspecific proctocolitis, schistosomiasis, tuberculosis, volvulus and pseudomembranous colitis. Conclusions: These data show that although chronic non specific proctocolitis and ulcerative colitis were the dominant diagnoses, Crohn's disease, ischemic bowel disease and diverticular disease also existed to a lesser extent and should be considered in the differential diagnosis of benign colorectal diseases. This study provides a base line data for future studies which would be taken up to investigate the link between benign/IBD and colorectal cancers in the local population.

• 천문학회보
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• 제35권1호
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• pp.28.2-28.2
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• 2010

We have investigated seven Extreme-Ultraviolet (EUV) bright points in the active region (AR 10926) on 2006 December 2 by the EUV imaging spectrometer (EIS) onboard Hinode spacecraft. We determined their Doppler velocities and non-thermal velocities from 15 EUV spectral lines (log T=4.7-7.2) by fitting each line profile to a Gaussian function. We present the Doppler velocity map as a function of temperature which corresponds to a different height. As a result, these active region bright points show two different types of characteristics. Type 1 bright point shows a systematic increase of Doppler velocity from -68 km/s (blue shift) at log T=4.7 to 27 km/s (red shift) at log T=6.7, while type 2 bright points have Doppler velocities in the range of -20 km/s and 20 km/s. Using MDI magnetograms, we found that only type 1 bright point was associated with the canceling magnetic feature at the rate of $2.4{\times}10^{18}$ Mx/hour. When assuming that these bright points are caused by magnetic reconnection and the Doppler shift indicates reconnection out flow, the pattern of the Doppler shift implies that type 1 bright point should be related to low atmosphere magnetic reconnection. We also determined electron densities from line ratio as well as temperatures from emission measure loci using CHIANTI atomic database. The electron densities of all bright points are comparable to typical values of active regions (log Ne=9.9-10.4). For the temperature analysis, the emission loci plots indicate that these bright points should not be isothermal though background is isothermal. The DEM analysis also show that while the background has a single peak distribution (isothermal), the EUV bright points, double peak distributions.

• 천문학회보
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• 제42권1호
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• pp.28.1-28.1
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• 2017

To investigate AGN outflows as a tracer of AGN feedback on the host galaxies, we perform integral-field spectroscopy of 20 type 2 AGNs at z<0.1 using the Magellan/IMACS and the VLT/VIMOS. The observed objects are luminous AGNs with the [O III] luminosity >$10^{41.5}erg/s$, and exhibit strong outflow signatures in the [O III] kinematics. We obtain the maps of the narrow and broad components of [O III] and $H{\alpha}$ lines by decomposing the emission-line profile. The broad components in both [O III] and $H{\alpha}$ represent the non-gravitational kinematics, (i.e., gas outflows), while the narrow components represent the gravitational kinematics (i.e., rotational disks), especially in $H{\alpha}$. By using the spatially integrated spectra within the flux-weighted size of the narrow-line region, we estimate the outflow energetics. The ionized gas mass is $(1.0-38.5){\times}10^5M_{\odot}$, and the mean mass outflow rate is $4.6{\pm}4.3M_{\odot}/yr$, which is a factor of ~260 higher than the mean mass accretion rate $0.02{\pm}0.01M_{\odot}/yr$. The mean energy injection rate is $0.8{\pm}0.6%$ of the AGN bolometric luminosity Lbol, while the mean momentum flux is $(5.4{\pm}3.6){\times}L_{bol}/c$, except for two most kinematically energetic AGNs. The estimated energetics are consistent with the expectations for energy-conserving outflows from AGNs, yet we do not find any supporting evidence of instantaneous star-formation quenching due to the outflows.

• 대한두개안면성형외과학회지
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• 제19권1호
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• pp.13-19
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• 2018

Background: $Abb{\acute{e}}$ flap technique is one of the most challenging operations to correct horizontal deficiencies in secondary cleft lip deformity. Since its first introduction, the operative method was dynamically modified from simple variation to complete conceptual change, but conventional $Abb{\acute{e}}$ flap has many drawbacks in esthetic and functional aspect. Our purpose was reconstructing the symmetry of Cupid's bow and central vermilion tubercle with minimal sequalae. Methods: From 2008 to 2016, this technique was applied to 16 secondary cleft lip patients who had total or more than 60% of unilateral deficiency of Cupid's bow and central lip or tubercle pouting deficiency. A quadrangular-shaped flap was transferred from vermilion including skin and white line of central or contralateral lower lip. Pedicle division and insetting were made at 9 (unilateral) or 10 (bilateral) days after transfer. Secondary lip revision was done with open rhinoplasty after wound maturation. Results: Overall satisfaction was high with modified technique. Scar was minimally noticeable on both upper and lower lip especially. Balanced Cupid's bow and symmetric vermilion tubercle were made with relatively small size of flap compared to conventional $Abb{\acute{e}}$ flap. An accompanying benefit was reduced ectropion of lower lip, which made balanced upper and lower lip protrusion with more favorable profile. Conclusion: A new modified $Abb{\acute{e}}$ flap technique showed great satisfaction. It is worth considering in secondary cleft lip patient who has central lip shortage and asymmetry of upper lip vermilion border line. Our technique is one of the substitutes for correction of horizontal and central lip deficiency with asymmetric Cupid's bow.

• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10797-10801
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• 2015

Background: To explore the molecular mechanisms of metastatic osteosarcoma (OS) by using the microarray expression profiles of metastatic and non-metastatic OS samples. Materials and Methods: The gene expression profile GSE37552 was downloaded from Gene Expression Omnibus database, including 2 human metastatic OS cell line models and 2 two non-metastatic OS cell line models. The differentially expressed genes (DEGs) were identified by Multtest package in R language. In addition, functional enrichment analysis of the DEGs was performed by WebGestalt, and the protein-protein interaction (PPI) networks were constructed by Hitpredict, then the signal pathways of the genes involved in the networks were performed by Kyoto Encyclopaedia of Genes and Genomes (KEGG) automatic annotation server (KAAS). Results: A total of 237 genes were classified as DEGs in metastatic OS. The most significant up- and down-regulated genes were A2M (alpha-2-macroglobulin) and BCAN (brevican). The DEGs were significantly related to the response to hormone stimulus, and the PPI network of A2M contained IL1B (interleukin), LRP1 (low-density lipoprotein receptor-related protein 1) and PDGF (platelet-derived growth factor). Furthermore, the MAPK signaling pathway and focal adhesion were significantly enriched. Conclusions: A2M and its interactive proteins, such as IL1B, LRP1 and PDGF may be candidate target molecules to monitor, diagnose and treat metastatic OS. The response to hormone stimulus, MAPK signaling pathway and focal adhesion may play important roles in metastatic OS.