• BMB Reports
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• 제43권9호
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• pp.635-641
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• 2010

Piwi proteins and Piwi-interacting RNAs (piRNAs) have been implicated in transposon control in germline from Drosophila to mammals. To examine the profile of small RNA expression in human cancer cells and explore difference in small RNA transcriptome, small RNA libraries prepared from wildtype, HILI overexpressed and HILI knockdowned Hela cells were sequenced using Solexa technology. piRNAs and other repeat-associated small RNAs were observed in Hela cells. By using in situ hybridization, piR-49322 was localized in the nucleolus and around the periphery of nuclear membrane in Hela cells. Following the overexpression of HILI, the retrotransposon elements LINE1 was significantly repressed, while LINE1-associated small RNAs decreased in abundance. The present study demonstrated that HILI along with piRNAs plays a role in LINE1 suppression in Hela cancer cell line.

• 천문학회보
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• 제36권2호
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• pp.115.1-115.1
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• 2011

We analyzed the line profiles of the planetary nebula (PN) NGC 7009 secured with the Keck I HIES and BOES's spectral data. The 5 positions were taken over the nebular image, 4 points on the bright rim plus 1 point at the central position. The covered spectral wavelength range was $3250{\AA}-8725{\AA}$ in these observations. We decomposed the lines of HI, HeI, HeII, CII, NIII, [ClIII], [NII], [OII], [OIII], [SII], [SIII], [ClIII], and [ArIII] using the IRAF and StarLink/Dipso. After correcting the Earth's movement and the PN's radial velocities, -48.6 & -48.9 km/s, respectively, for the Keck & BOES, we produced the line profiles in a velocity scale. The zero velocity at each line profile clearly indicates which part of the components is approaching or receding, giving a general information of the kinematical structure. Almost all of the low-to-medium excitation lines, such as [NII], [SII], [O III], and [ArIII], secured at the central position and four positions along the major & minor axes, showed 3 components, double peak + a wide wing component, suggesting the fast outflow structures are present. The overall geometry is a prolate shell which also has a fainter outer shell in the halo zone, but there appears to be some peculiar sub-structures inside the main shell. The high excitation He I, HeII, NIII lines which might be formed close to the inner boundary of the shell show unusual features, completely different from the other lines. The HeII and these high excitation lines may be indicative of a relative recent fast outflow from the central star and the permitted lines such as NIII might be affected by the innermost structure. We discuss a possible presence of a jet-like fast outflow structure in an out-flow axis different from the main axis of the spheroid shell.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
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• pp.15-15
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• 1993

Revised Yale Isochrone(Green et al, 1987)과 Lee의 HB simulation data(LEE '||'&'||' Demarque 1990)을 이용하여 Park이 만든 CMD simulation program(Park 1983).에 쌍성을 첨가하면 CMD에 어느 정도의 영향을 나타내게 되는가를 조사하였다. MS, SGB와 RGB는 큰 변화가 없었으나, HB에서는 많은 변화를 나타내었다. 193919 S02401193919 ^x We have observed the emission of HC3N J= 4-3, 5-4 10-9 and 12-11 transitions toward the Sgr B2 central region in an area of 150"XISO" with resolutions of16"-48". The intensities and central velocities of line profiles show significant variations with positions. In contrast to the in tensities of the low J-level transitions which gradually increase from the central source toward the outside region the HC3N emission of the high J-level transition become stronger toward the central radio continuum source MO5. Systematic chainge in the radial velocity of each line profile occurs along north-south direction there are a few peaks in most line profiles, and these indicate that there not multiple velocity components along the line of sight. Distributions of excitation temperah at and column density which were estimated from the excitation calculations show the existence of a small(IxEpc),hot(Tex> SOK) core which contains two tempegatlue peaks at -15" east and north of MDS. The column density of HCaN is (1-3):n1014cm-2. Column density at distant position from MD5 is larger than that in the (:entral region. We have deduced that this hot-core has a mass of 10sR1 which i:s about an order of magnitude larger those obtained by previous studies.previous studies.

• 전기전자학회논문지
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• 제25권1호
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• pp.95-100
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• 2021

조선소에서 선체 블록과 용접 피더의 위치를 알면 작업자의 위치 정보를 쉽게 얻을 수 있다. 이 데이터는 작업장 안전 모니터링 시스템 구축에 매우 유용하다. 그러나 선체 구조와 용접 공정의 특수성 때문에 작업장에 고정 통신망을 적용하기 어렵다. 본 연구에서는 전용 통신선을 대신할 수 있는 유도 전력선 통신을 선체블록과 같은 금속매체에 적용하는 기술을 검토하였다. 용접기의 전원 케이블에 설치할 유도 결합기로 페라이트 코어를 사용하였고, 금속 블록의 지지대에 체결할 결합기로 나노 결정질 코어를 적용하였다. 제안된 커플러는 COMSOL AC/DC 모듈로 3차원 모델링 하였고 동작 원리를 시각화하기 위하여 유한 요소 해석을 수행하였다. 알루미늄 프로파일을 사용한 금속블록 통신 성능 테스트에서 용접 전극의 블록 접촉으로 통신 채널이 형성되었을 때 대역폭은 6 Mbps 이상 유지되었다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권6호
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• pp.2771-2774
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• 2012

Aim: Tumors of upper gastrointestinal tract are among the cancers that have a quite lethal course. Cytotoxic chemotherapy is the most efficient therapeutic modality for metastatic gastric cancer. In patients who do not respond to first-line treatment, the response rate to second-line therapies is generally low and the toxicity rates high. This study concerned the efficacy and the side effect profile of second-line therapy with irinotecan in the patients who were being followed-up with the diagnosis of metastatic gastric cancer in $\dot{I}$zmir, Turkey. Materials and Methods: We retrospectively evaluated the efficacy and toxicity in 31 patients with metastatic gastric adenocarcinoma who presented to the polyclinic of Medical Oncology of Izmir Ataturk Education and Research Hospital between May 2008 and July 2011. All received chemotherapy regimens containing cisplatin, fluoropyrimidine (5-FU) and docetaxel as the first-line therapy for late stage disease. Irinotecan as a single agent was given at a dose of 210 mg/$m^2$ on each 21 days. Irinotecan (180 mg/$m^2$ on day 1), 5-FU (500 mg/$m^2$ on days 1-2) and leucovorin (LV; 60 mg/$m^2$ on days 1-2) as a combined regimen were given over a 14 day period. Results: Median age was 54 (range, 31-70). Irinotecan was given as a combined regimen for median 6 cycles (range, 3-12) and as a single agent for median 3 cycles (range, 1-10). Metastases were detected in one site in six patients (19%), in two different sites in 17 patients (55%) and in three or more sites in eight patients (26%). Four patients (12.9%) showed partial response and six patients (19.3%) showed stable disease. Progression-free survival (PFS) was found to be 3.26 months (95% CI, 2.3-4.2). Median overall survival (OS) was found to be 8.76 months (95% CI, 4.5-12.9). The most commonly seen grade 3/4 side effect was neutropenia but the the therapy was generally well-tolerated. Conclusions: In this study, it was demonstrated that second-line therapy with irinotecan given following the first-line therapy with cisplatin, fluoropyrimidine (5-FU) and docetaxel was efficient and safe. Further studies are needed for confirmation.

• 대한심미치과학회지
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• 제4권1호
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• pp.23-36
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• 1995

The purpose of this artic1e is to compare soft tissue profiles between Korean adults with normal occ1usion and malocclusin and to identify the differences between them. The subjects of this cephalometric study were 40 males with normal occlusion(Group 1), 27 females with normal occlusion(Group 2), 28 adults with Angle's Class II malocclusion(Group 3) and 41 adults with Angle's Class III malocclusion(Group 4). The results of this study were as follows ; 1) People with Angle's Class II malocclusion had tendency to have more labial tipping of lower teeth than people with normal occ1usion. Through NOA angle measurement, it was determined that people with Angle's Class II malocclusion had more protruding midface than people with normal occlusion and people with Angle's Class III malocclusion had retruding midface. 2) Through Powell's esthetic triangle analysis, it was determined that people with Angle's Class II malocclusion had retruding chin and protruding nose. 3) No significant differences between people with normal occlusion and maloclusion could be identified by measuring soft tissue profile angle basis of S-NS plane. 4) There were significant differences between groups with normal occlusion and malocclusion by measuring Facial convexity angle(Significance level 99%). 5) By measuring the distance between each landmark basis of N-Pog plane, People with Angle's Class II malocclusion were identified as having more protruding midface, but there were no significant differences between people with normal occlusion and Angle's Class III malocclusion. 6) By measuring the vertical dimension of the face, it was determined that the lower facial height was higher than the upper facial height in all groups, particularly in group with Angle's Class III malocclusion. 7) By measuring the lips basis of E-line and S-line, it was determined that people with Angle's Class III malocclusion had more, protruding lower lips than people with normal occlusion, while people with normal occlusion, while people with Angle's Class II malocclusion had more protruding upper lips. By measuring the distance between the superior sulcus and inferior sulcus basis of H-line, people with Angle's Class II malocclusion had thicker upper lips than the other's.

• 한국인터넷방송통신학회논문지
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• 제20권6호
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• pp.101-107
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• 2020

노면측정은 노면 관리에서 노면의 평탄화된 정도 및 변위를 정량화하는 필수적인 과정이다. 보다 안전한 노면 관리 및 신속한 유지보수를 위해 이동체에서의 정밀한 노면 측정은 매우 중요하다. 본 논문에서는 이동체에서 측정가능한 정밀 노면측정 시스템을 제안한다. 제안 노면측정 시스템은 고성능의 선레이저 센서를 사용하여 노면 표면의 정밀한 측정을 지원한다. 또한 RTK로 부터 획득한 위치 데이터를 정합하여 종/횡방향 프로파일 측정이 가능하고 속도기반 적응적인 갱신 알고리즘을 통해 실시간적인 모니터링이 가능하다. 제안 시스템을 평가하기 위하여 Gocator 선레이저 센서, MRP 모듈, 및 NVIDIA Xavier 프로세서를 시험용 이동체에 탑재하여 노면에서 시험하였다. 시험 결과 MSE(mean square error) 기준 정확한 프로파일 측정이 가능함을 보인다. 제안 시스템은 도로의 상태 평가뿐 만 아니라 인접 지반의 영향도 평가에 활용될 수 있다.

• Bulletin of the Korean Chemical Society
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• 제31권2호
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• pp.315-326
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• 2010

This study examined the overlapping resonances in the systems involving 1 open and 2 closed channels using the phase-shifted version of multichannel quantum-defect theory (MQDT). The results showed that 21 patterns for the q reversals in the autoionization spectra are possible depending on the relative arrangements of the two simple poles and roots of the quadratic equations. Complete cases could be generated easily using the q zero planes determined using only 3 asymmetric spectral line profile indices. The transition of the spectra of the coarse interloper Rydberg series from the lines into a structured continuum by being dispersed onto the entire Rydberg series was found. The overall behavior of the time delays was found to be governed by the dense Rydberg series, which is quite different from the one of the autoionization cross sections that is governed by an interloper, indicating that different dynamics prevail for them. This is in contrast to the two channel system where both quantities behave similarly. The dynamics obtained in the presence of overlapping resonances is as follows. The absorption process is instant and dominated by a transition to the interloper line. This process is followed by rapid leakage into the dense Rydberg series, which has a longer residence time before ionization than that of the interloper state. This is because the orbiting period is proportional to $\upsilon^3$ so that an excited electron has a shorter lifetime in the interloper state belonging to a lower member of the Rydberg series.

• 천문학회보
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• 제40권2호
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• pp.53.3-53.3
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• 2015

We analyzed both HCN J=1-0 and HNC J=1-0 line profiles to study the inflow motions in different evolutionary stages of massive star formation; infrared dark clouds (IRDCs), high-mass protostellar object (HMPOs), and ultra-compact HII regions (UCHIIs). The infall asymmetry in HCN spectra seems to be prevalent throughout all the three evolutionary phases, with IRDCs showing the largest excess in blue profile. In the case of HNC spectra, the prevalence of blue sources does not appear, excepting for IRDCs. We suggest that this line is not appropriate to trace infall motion in evolved stages of massive star formation because of an astrochemical effect. This result spotlights the importance of considering chemistry in dynamical study in star-forming regions. The fact that the IRDCs show the highest blue excess in both infall tracers indicates that the most active infall occurs in the early phase of star formation, i.e., the IRDC phase rather than in the later phases. However, the UCHIIs is likely still accreting matters. We also found that the absorption dips of the HNC spectra in all blue sources are red--shifted relative to their central velocities. These red-shifted absorption dips may indicate the observational signature of overall collapse although observations with better resolutions are needed to examine this feature more in detail.

• 천문학회보
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• 제38권2호
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• pp.88.1-88.1
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• 2013

We have investigated vertical motions of plasma in the pores and changes of the motions with height by using high time and spatial resolutions data obtained by the Fast Imaging Solar Spectrograph (FISS) of the 1.6 meter New Solar Telescope (NST). We infer the LOS velocity by applying the bisector method to the wings of CaII 854.2 nm line profile. We find that (1) upflow velocity in the pores decreases with height and turns into downward in the upper chromosphere; (2) 3 min and 5 min oscillations are found from the Doppler velocity in the pore at various wavelengths from the wing (${\pm}2.35{\AA}$) to the core (${\pm}1.25{\AA}$) of the CaII line; and (3) power of high (low) frequency oscillation obtained from the CaII intensity increases (decreases) with height. We discuss the physical implications of our results in view of the connection of LOS plasma flows in a concentrated magnetic flux (pore) between the photosphere and the low chromosphere.