• 대한한방부인과학회지
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• 제21권3호
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• pp.18-33
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• 2008

Purpose: The research is to investigate the effect of TFE on apoptosis of human-derived breast cancer cells, to find out the relationship with apoptosis. Methods: Human-derived breast adenocarcinoma cell line, MCF-7 cells were treated by TFE with various concentration. The inducement effect of TFE on cell apoptosis was observed with MTT assay and the relationship between the treatment and apoptosis was investigated with FACS analysis, TUNEL assay and DNA laddering assay and the change in the protein levels of PARP and caspase-3 activities were also observed. The release of cytochrome-c was observed to find out the pathway of apoptosis induced by TFE. Results: The cell apoptosis was significantly induced in MCF-7 cells treated with TFE in concentration-dependent and time-dependent manner. It was verified by FACS analysis, TUNEL assay, DNA laddering assay that cell-death was caused not by necrosis but by apoptosis. The activity of PARP and caspase were increased concentration-dependently. The release of cytocrome-c was decreased in proportion to the concentration of the fruit extract. It therefore demonstrated that mitochondria were involved in apoptosis induced by TFE. The appearance of Bcl-2 protein was decreased concentration-dependently. Conclusion: The treatment by TFE induced apoptosis of human breast adenocarcinoma cell line, MCF-7. It seems likely that cell-death was caused by apoptosis and mitochondria were involved in it. The mechanism of protein change causing apoptosis seems related to the inhibition of Bcl-2 protein, the promotion of inversion from cytochrome-c into cytosol, the activation of caspase and the promotion of PARP cleavage.

• 천문학회보
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• 제38권2호
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• pp.90.1-90.1
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• 2013

To better understand the physics underlying the eruption of prominences in solar active regions, we studied eruption processes of two active prominences located in the active region NOAA 11261 using multi-wavelength observational data with high temporal and spatial resolution. Specifically, we examined (1) the temporal variation of morphology and plasma properties of the two active prominences, (2) magnetic fields and their evolution on the photospheric surface underneath the prominences, and (3) the time profiles and locations of radio, EUV, and soft/hard X-ray emissions produced by the M9.3 flare related to the prominence eruption. As a result, we found that: (1) a prominence F1 began to erupt and expand as the abrupt and intense EUV brightening occurred in the localized region underneath the western part of F1 at 03:45 UT prior to the peak time of the M9.3 flare, (2) F1 split into two parts: i.e., the western part asymmetrically erupted by producing the M9.3 flare with microwave source motions along the magnetic polarity inversion line between the two flare ribbons, while the eastern part coalesced into a pre-existing prominence F2, (3) F2 became unstable due to the coalescence with the eastern part of F1, and then it partially erupted with clockwise untwisting motions.

• 대한기계학회논문집B
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• 제28권4호
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• pp.425-432
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• 2004

The objective of this study is a qualitative comparison between line-integrated OH chemiluminescence(OH$\^$*/) image and its Abel inverted image to investigate the flame structure at different phase of the oscillating pressure field. PIV(Particle Image Velocimetry) measurements were conducted under non-reacting conditions to see the global flow structure and NOx emission was measured to investigate the effect of fuel-air premixing on combustion instability and emission characteristics. Experiments were carried out in an atmospheric pressure, laboratory-scale dump combustor operating on natural gas. Combustion instabilities in present study exhibited a longitudinal mode with a dominant frequency of ∼341.8㎐, which corresponded to a quarter wave mode of combustor. Heat release and pressure waves were in-phase when instability occurred. Results gave an insight about the location where the strong coherence of pressure and heat release existed. Also an additional information on active control to suppress the combustion instabilities was obtained. For lean premixed combustion, strong correlation between OH$\^$*/ and NOx emissions was expected largely due to the exponential dependence of thermal NOx mechanism on flame temperature.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 추계학술대회
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• pp.1146-1151
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• 2004

Measurements of OH chemiluminescence in an atmospheric pressure, laboratory-scale dump combustor at equivalence ratios ranging from 0.63 to 0.89 were reported. The signal from the first electronically excited state of OH to ground state was detected through a band-pass filter with an ICCD. The objectives of this study are two: One is to see the effects of equivalence ratio on global heat release rate and local Rayleigh index distribution. To get the local Rayleigh index distribution, the line-of-sight images were inverted by tomographic method, such as Abel de-convolution. Another aim is to investigate the validity of using OH chemiluminescence acquired with an ICCD as a qualitative measure of local heat release. For constant inlet velocity and temperature, the overall intensities of OH emission acquired at different equivalence ratio showed periodic and higher value at high equivalence ratio. OH intensity averaged over one period of pressure increased exponentially with equivalence ratio. Local Rayleigh index distribution clearly showed the region of amplifying or damping the combustion instability as equivalence ratio increased. It could provide an information/insights on active control such as secondary fuel injection. Finally, local heat release rate derived from reconstructed OH images were presented for typical locations.

• 한국지하수토양환경학회:학술대회논문집
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• 한국지하수토양환경학회 2001년도 추계학술발표회
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• pp.92-96
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• 2001

Although the problem of seawater intrusion at the coastal aquifer was recognized before over one hundred years at the coastal aquifer, much groundwater keep on being salinitized by several reasons such as groundwater exhaustion, coastalline change, and human activities. The horizontal and vertical electrical soundings and geostatistical methods were used to define the local characteristics of saltwater intrusion and to estimate the saltwater interface in the southeastern area of the Pusan City. The 24 points of the Schlumberger vertical electrical soundings(VES) to loom depth and the 2 lines of dipole-dipole horizontal soundings are peformed. The resistivity data have lognormal distributions. The horizontal extents of saline water intrusion were estimated from the inversion of horizontal prospecting data. Lognormal ordinary kriging is used in A-A' resistivity profiles on May and July because the data have stationary models in semivariograms. Lognormal IRF-k kriging is used for the isopleth maps using vertical resistivity data. The 10 ohm-m resistivity line on the isopleth maps of 21m, 30m, 50m, and 70m depth using resisitivity data measured in July is sifted to the east, cpomparing that of the isopleth maps measured in May. The kriged vertical and horizontal resistivity isopleth maps suggested that the geostatistical methods can be used to define the variation of earth resistivity distribution at the saltwater interface.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 춘계 학술발표회 초청강연 및 논문집
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• pp.142-152
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• 2008

SPT-Uphole method was introduced for the evaluation of near subsurface shear wave velocity (Vs) profile. In SPT-Uphole method, SPT (Standard Penetration Test) which is common in geotechnical site investigation was used as a source and several surface geophones in line were used as receivers. 1D shearwave velocity profile can be obtained in the manner of downhole method, Vs distribution map which is the triangular shape around the boring point can be developed by tomography inversion. To obtain the exact travel time information of shear wave component, a procedure using the magnitude summation of vertical and horizontal components was used based on the evaluation of particle motion at the surface. It was verified that proposed method could give reliable Vs distribution map through the numerical study using the FEM (Finite Element Method) model. Finally, SPT-Uphole method was performed and the feasibility of proposed method was verified in the field.

• 천문학회지
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• 제42권1호
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• pp.9-15
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• 2009

A necessary condition for the formation of a filament is magnetic helicity. In the present paper we seek the origin of magnetic helicity of intermediate filaments. We observed the formation of a sinistral filament at the boundary of a decaying active region using full-disk $H_{\alpha}$ images obtained from Bi Bear Solar Observatory. We have measured the rate of helicity injection during the formation of the filament using full-disk 96 minute-cadence magnetograms taken by SOHO MDI. As a result we found that 1) no significant helicity was injected around the region (polarity inversion line; PIL) of filament formation and 2) negative helicity was injected in the decaying active region. The negative sign of the injected helicity was opposite to that of the filament helicity. On the other hand, at earlier times when the associated active region emerged and grew, positive helicity was intensively injected. Our results suggest that the magnetic helicity of the intermediate filament may have originated from the helicity accumulated during the period of the growth of its associated active region.

• 천문학회지
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• 제33권1호
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• pp.47-55
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• 2000

Nonpotential characteristics of magnetic fields in AR 5747 are examined using Mees Solar Observatory magnetograms taken on Oct. 20, 1989 to Oct. 22, 1989. The active region showed such violent flaring activities during the observational span that strong X-ray flares took place including a 2B/X3 flare. The magnetogram data were obtained by the Haleakala Stokes Polarimeter which provides simultaneous Stokes profiles of the Fe I doublet 6301.5 and 6302.5. A nonlinear least square method was adopted to derive the magnetic field vectors from the observed Stokes profiles and a multi-step ambiguity solution method was employed to resolve the $180^{\circ}$ ambiguity. From the ambiguity-resolved vector magnetograms, we have derived a set of physical quantities characterizing the field configuration, which are magnetic flux, vertical current density, magnetic shear angle, angular shear, magnetic free energy density, a measure of magnetic field discontinuity MAD and linear force-free coefficient. Our results show that (1) magnetic nonpotentiality is concentrated near the inversion line in the flaring sites, (2) all the physical parameters decreased with time, which may imply that the active region was in a relaxation stage of its evolution, (3) 2-D MAD has similar patterns with other nonpotential parameters, demonstrating that it can be utilized as an useful parameter of flare producing active region, and (4) the linear force-free coefficient could be a evolutionary indicator with a merit as a global nonpotential parameter.

• 천문학회보
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• 제42권2호
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• pp.81.3-81.3
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• 2017

In this paper, we report a small-scale emerging island and double arc loops, which are associated with a M6.5 flare, in Active Region 12371. We investigate the spatial and temporal changes of both photospheric magnetic fields using SDO/HMI data and coronal magnetic structures obtained from nonliner force-free field (NLFFF) extrapolation. From the vector magnetograms, we find a small-scale emerging island near the main polarityy inversion line about three hours before the flare. The island has a strong shear angle, which is determined by difference between transverse component of observed field and potential field, of around 90 degrees. Furthermore, the NLFFF well reproduces a sigmoidal structure seen in SDO/AIA 94, which is consistent with the double arc loops configuration suggested by Ishiguro and Kusano (2017) who introduced a magnetic configuration showing the double arc instability. The observed emerging island is located among the double arc loops, which is also supproted by their model. Finally, there was an eruption (M6.5 flare) associated with the loops. We discuss a possible role of the double arc instability for the eruption.

• 천문학회지
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• 제53권1호
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• pp.1-7
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• 2020

The recent study of Chae et al. (2017) found a one-to-one correspondence between plasma blobs outflowing along a ray formed after a coronal mass ejection (CME) and small X-ray flares. In the present work, we have examined the spatial configuration and the eruption process of the flares that are associated with the blobs by analyzing EUV images and magnetograms taken by the SDO/AIA and HMI. We found that the main flare and the successive small flares took place in a quadrupolar magnetic configuration characterized by predominant magnetic fields of positive polarity, two minor magnetic fragments of negative polarity, and a curved polarity inversion line between them, which suggests that the formation process of the blobs may be similar to that of the parent CME. We also found that the successive flares resulted in a gradual change of the quadrupolar magnetic configuration, and the relevant migration of flaring kernels. The three-dimensional geometry and the property of the current sheet, that is often supposed to be embedded in an observed post-CME ray, seem to keep changing because of mutual feedback between the successive flares and the temporal change of the magnetic field configuration. Our results suggest that the observed post-CME rays may not reflect the characteristics of the current sheet responsible for the impulsive phase of the flare.