• Title/Summary/Keyword: Lin28

Search Result 193, Processing Time 0.02 seconds

Retrograde Analysis of Clinical Characteristics of Bone Metastasis in 1,031 Cases of Preliminarily Diagnosed Nasopharyngeal Carcinoma

  • Zhao, Chang-Lin;Qian, Guo-Qiang;Chen, Xiao-Yin;Chen, Chao
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.8
    • /
    • pp.3785-3788
    • /
    • 2014
  • Purpose: To explore the clinical characteristics of bone metastasis (BM) in a large sample of preliminarily diagnosed nasopharyngeal carcinomas (NPCs). Methods: The sample consisted of 1,031 patients diagnosed with NPC at first visitg clinics between October 1989 and June 2012. Several parameters including metastasis locus, T/N staging, diagnosis, therapy and prognosis of BM were analyzed retrospectively. Results: In 70 patients who had been preliminarily diagnosed with BM, the incidence of BM in N0, N1, N2 and N3 stage was 5.7%, 17.2%, 50.2%, and 25.7%, respectively, while the incidence in T0, T1, T2 and T3 stage was 0%, 23.8%, 47.6% and 28.6% respectively. BM occurred in most common in vertebral column, rib, sternum, ilium and femur. Positive rate of Epstein-Barr virus antibody was 77.6%. The median survival time was 12 months. Conclusion: The incidence of BM in NPC preliminarily diagnosed is about 7% and it is related to N classification but not T classification.

Effects of Aqueous Extract of Schizandrae Fructus on Lead-Induced Change of Monoamine Neurotransmitters in Hippocampus

  • Zhao, Rong Jie;Zhao, Zheng Lin;Zhao, Xiu Feng;Zhao, Guang Wen;Li, Meng Quan;Wu, Yi Yan;Li, Jing Qiu;Guan, Li Xin;Kim, Sang-Chan
    • Herbal Formula Science
    • /
    • v.17 no.2
    • /
    • pp.143-150
    • /
    • 2009
  • The effects of aqueous extract of Schizandrae Fructus (AESC) on lead (Pb)-induced changes of monoamine neurotransmitters in the hippocampus (HIP) of adult rats were investigated. Male Sprague-Dawley rats were received intraperitoneal (i.p.) administration of Pb acetate (5 mg/kg/d) for 28 days and sacrificed 7 days after the last administration. Concentrations of norepinephrine (NE), dopamine (DA), serotonin (5-HT), 5-hydroxyindole acetic acid (5-HIAA) in HIP were measured by HPLC. There were significant decreases of NE, DA, 5-HT and 5-HIAA in Pb treated rats (P < 0.05), while pretreatment with AESC (100 mg/kg/d or 300 mg/kg/d, p.o., 2 h before Pb) greatly inhibited the decrease of monoamine transmitters, respectively (P < 0.05). Also, AESC (300 mg/kg/d) significantly increased the reduction of glutathione contents and superoxide dismutase activities in HIP induced by chronic Pb. These results suggest that AESC ameliorates Pb-induced depletion of monoamine neurotransmitters in HIP through its antioxidant activity.

  • PDF

The Change of Spatial Structure of a Lishu Settlement on the Upper Reaches of Tumen Riverside in China (두만강 북안 상류 농촌마을 공간구조의 변화 -화룡시 숭선진 이수마을을 대상으로-)

  • Lin, Jinhua;Kim, Taiyoung
    • Journal of the Korean Institute of Rural Architecture
    • /
    • v.8 no.3
    • /
    • pp.83-90
    • /
    • 2006
  • 1) Lee-Su village is located in a riverside of an upper Tu-men river. Since an upper stream of Tu-men river is narrow and easy to pilot a boat, early in the past, it facilitated the form of the village near to the North Korean. 2) The form of the village is parabolic from the founding period. That is, increasing the number of houses in the time of the Cultural Revilution Campaign, and the Japanese colony, the village has transformed into the bigger size about 72 families from the small town. After the cultural revolution, due to private asset allowed in accordance with the Chinese Reform and Open Policy, the number of families in the town and the population have been decreased. As a result, 28 families live in the village currently. 3) The town which was well-ordered in the Japanese colonial period has been changed to a very disordered and agricultural town, owing to the decrease of the families A road system has been also ruined naturally in accordance with the decline of the number of the families.

  • PDF

Assessment of Internal Dose by $^3H\;&\;^{14}C$ of Total Diet for Inhabitants near Wolsung Nuclear Power Plants

  • Park, G.;Lin, X.J.;Kim, W.;Kang, H.D.;Doh, S.H.;Kim, D.S.;Kim, C.K.
    • Journal of Radiation Protection and Research
    • /
    • v.28 no.1
    • /
    • pp.51-57
    • /
    • 2003
  • To assess the internal dose by $^3H\;&\;^{14}C$ in total diet of inhabitants near Wolsung Nuclear Power Plants, TFWT, OBT and $^{14}C$ concentration in total diet was analyzed for collection region and time. TFWT, OBT and $^{14}C$ concentrations were in the range of 3.19-42.2 Bq/L, 1.00-39.4 Bq/L, and 0.230-0.855 Bq/gC, respectively. The calculated annual effective dose with TFWT, OBT and $^{14}C$ is $6.10{\times}10^{-5}mSv/y,\;3.71{\times}10^{-5}mSv/y\;and\;7.08{\times}10^{-3}mSv/y$, respectively. And then annual internal dose with total diet for inhabitants near Wolsung NPPs is about $7.18{\times}10^{-3}mSv/y$, which is about 0.72% of annual effective dose limit 1 mSv/y.

Antiinflammatory Constituents from the Roots of Smilax bockii warb.

  • Xu Jing;Li Xian;Zhang Peng;Li Zhan-Lin;Wang Yi
    • Archives of Pharmacal Research
    • /
    • v.28 no.4
    • /
    • pp.395-399
    • /
    • 2005
  • From $70\%$ ethanol extract of the roots of Smilax bockii warb., seven flavonoids, kaempferol (1), $kaempferol-7-O-\beta-D-glucopyranoside$ (2), quercetin (3), isorhamnetin (4), (+)-dihydro­kaempferol (5), engeletin (6), isoengeletin (7), and $n-butyl-\beta-D-fructopyranoside$ (8), caffeic acid n-butyl ester (9) were isolated and identified by means of chemical and spectroscopic. Compounds 2, 4, and 6-9 were isolated for the first time from the roots of S. bockii and compounds 2, 8, and 9 were firstly isolated from the genus Smilax. In addition, using the SEAP (Secreted alkaline phosphatase) assay system, we investigated the in vitro anti-inflammatory activity of the $70\%$ ethanol extract of the roots of S. bockii, which showed moderate activity in inhibiting $TNF-\alpha-induced NF-{\kappa}B$ activation with an $IC_{50}$ value of $166.6 {\mu}g/mL$.

Characteristics of Refractive Index Profiles at Different Temperatures in $LiNbO_3$ and $KTiOPO_4$ Waveguide Formed by 350 keV Light Ions

  • Wang, Ke-Ming;Feng Chen;Hui Hu;Xia, Hui-Hao;Wang, Xue-Lin;Shi, Bo-Rong;Lu, Qing-Ming
    • Journal of the Korean Vacuum Society
    • /
    • v.12 no.S1
    • /
    • pp.28-32
    • /
    • 2003
  • Both $LiNbO_3$ and $KTiOPO_4$ samples were implanted with 350 keY $H^+$ and $He^+$ ions at different doses ranging from $1 ${\times}$\times10^{16}$ to of $5 ${\times}$\times10^{16}$ ions/$\textrm{cm}^2$. Single and multi-energy implantations were performed at room temperature. Mono-mode or a few modes in both $LiNbO_3$ and $KTiOPO_4$ waveguides were observed. The effect of temperature on the refractive index profiles of $LiNbO_3$ and $KTiOPO_4$ waveguids was studied. The temperature covered from room temperature, $200^{\circ}C$, 194.5 K (dry ice) and 77K (liquid nitrogen). Different mechanisms are needed to interpret the observed behavior. A n, increased mono-mode $LiNbO_3$ waveguide was formed by multi-energy keV $He^+$ ions.

Dengue-related Information Needs and Seeking Behavior of the General Public in Singapore

  • Shaheen, Majid;Hu, Ye;Hui, Yik Tan;Lin, Xinying
    • Journal of Information Science Theory and Practice
    • /
    • v.7 no.1
    • /
    • pp.17-28
    • /
    • 2019
  • Dengue infection is becoming a serious global health threat. Public awareness is a pre-requisite for the successful implementation of dengue prevention programs. The main purpose of this study was to investigate dengue-related information needs and seeking behavior of the general public in Singapore. Some areas covered by this study were: importance of dengue-related information needs, preferred channels for seeking information, and respondents' perceptions of using dengue-related information. A questionnaire was used for data collection and 152 individuals participated in this study. Data analysis showed that the most sought after information concerned: dengue-related medicines, primary symptoms of dengue infection, and different possible treatments. The popular channels for seeking information were: websites of hospitals and other health agencies, the social media, television, and newspapers. Medical staff, such as doctors and nurses, were trusted for providing accurate information. Although credibility of social media was considered low, respondents were using it due to its easy accessibility. The findings of this study will be useful to government health departments in Singapore as well as in other countries suffering from dengue, hospitals, and public welfare agencies involved in public health awareness campaigns.

Comparative Study of Flux Regulation Methods for Hybrid Permanent Magnet Axial Field Flux-switching Memory Machines

  • Yang, Gongde;Fu, Xinghe;Lin, Mingyao;Li, Nian;Li, Hao
    • Journal of Power Electronics
    • /
    • v.19 no.1
    • /
    • pp.158-167
    • /
    • 2019
  • This research comparatively studies three kinds of flux regulation methods, namely, stored capacitor discharge pulse (SCDP), constant current source pulse (CCSP), and quantitative flux regulation pulse (QFRP), which are used for hybrid permanent magnet (PM) axial field flux-switching memory machines (HPM-AFFSMMs). Through an analysis of the operation principle and the series hybrid PM flux regulation mechanism of the objective machine, the circuit topologies and flux regulation process of these flux regulation methods are addressed in detail. On the basis of a simulation, the flux regulation characteristics of the researched machine during the magnetization and demagnetization processes are comparatively evaluated. Then, machine performance, including back EMF, direct and quadrature axis inductances, and magnetization and demagnetization characteristics, is quantitatively investigated. Results show that the QFRP enables the HPM-AFFSMM to achieve a less harmonic component of back EMF by approximately 7.28% and 7.97% at the magnetization and demagnetization states, respectively, and a more complete magnetization process than the SCDP and CCSP.

Influence of prestressing on the behavior of uncracked concrete beams with a parabolic bonded tendon

  • Bonopera, Marco;Chang, Kuo-Chun;Lin, Tzu-Kang;Tullini, Nerio
    • Structural Engineering and Mechanics
    • /
    • v.77 no.1
    • /
    • pp.1-17
    • /
    • 2021
  • The influence of prestress force on the fundamental frequency and static deflection shape of uncracked Prestressed Concrete (PC) beams with a parabolic bonded tendon was examined in this paper. Due to the conflicts among existing theories, the analytical solutions for properly considering the dynamic and static behavior of these members is not straightforward. A series of experiments were conducted for a total period of approximately 2.5 months on a PC beam made with high strength concrete, subsequently and closely to the 28 days of age of concrete. Specifically, the simply supported PC member was short term subjected to free transverse vibration and three-point bending tests during its early-age. Subsequently, the experimental data were compared with a model that describes the dynamic behavior of PC girders as a combination of two substructures interconnected, i.e., a compressed Euler-Bernoulli beam and a tensioned parabolic cable. It was established that the fundamental frequency of uncracked PC beams with a parabolic bonded tendon is sensitive to the variation of the initial elastic modulus of concrete in the early-age curing. Furthermore, the small variation in experimental frequency with time makes doubtful its use in inverse problem identifications. Conversely, the relationship between prestress force and static deflection shape is well described by the magnification factor formula of the "compression-softening" theory by assuming the variation of the chord elastic modulus of concrete with time.

Bridge-edges Mining in Complex Power Optical Cable Network based on Minimum Connected Chain Attenuation Topological Potential

  • Jiang, Wanchang;Liu, Yanhui;Wang, Shengda;Guo, Jian
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • v.15 no.3
    • /
    • pp.1030-1050
    • /
    • 2021
  • The edges with "bridge characteristic" play the role of connecting the communication between regions in power optical cable network. To solve the problem of mining edges with "bridge characteristic" in provincial power optical cable network, the complex power optical cable network model is constructed. Firstly, to measure the generated potential energy of all nodes in n-level neighborhood local structure for one edge, the n-level neighborhood local structure topological potential is designed. And the minimum connected chain attenuation is designed to measure the attenuation degree caused by substituted edges. On the basis of that, the minimum connected chain attenuation topological potential based measurement is designed. By using the designed measurement, a bridge-edges mining algorithm is proposed to mine edges with "bridge characteristic". The experiments are conducted on the physical topology of the power optical cable network in Jilin Province. Compared with that of other three typical methods, the network efficiency and connectivity of the proposed method are decreased by 3.58% and 28.79% on average respectively. And the proposed method can not only mine optical cable connection with typical "bridge characteristic" but also can mine optical cables without obvious characteristics of city or voltage, but it have "bridge characteristic" in the topology structure.