• 양봉협회회보
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• 통권350호
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• pp.54-55
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• 2009

• 한국염색가공학회지
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• 제22권1호
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• pp.71-76
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• 2010

In this study the optimum dyeing conditions and blocking effect of UV deodorization efficiency of Ligustrum japonicum Thunb were investigated. Colorants were water-extracted from Ligustrum japonicum Thunb fruit and freeze-drided to obtain colorants powder. The effects of dye concentration, dyeing temperature, dyeing time, and the number of dipping count were studied. Fastness to dry cleaning, rubbing, perspiration, and light were measured according to KS K 0644, KS K 0650, KS K 0715 and KS K 0700, respectively. In order to examine the dyeability according to dyeing conditions, reflectance of fabrics were measured by using UV/VIS spectrophotometer. The bath ratio was 1:20. Dyeing concentration was 100, 200, 300, 400 and 500% on the weight of fiber. Dyeing time was 20, 40, 60, and 80 minutes. Dyeing temperature was 20, 40, 60, 80, and $100^{\circ}C$. The infrared high pressure dying machine was used. As dyeing concentration increased, dye adsorption increased up to 400% and it slowed down. Dye uptake was increased with raising themperature up to $80^{\circ}C$ and it slowed down. Dye adsorption occurred rapidly at first 20 minutes and then it slowed down and reached almost maximum dye uptake at 60 min. Dye uptake increased by repeated dyeing. Therefore, it is considered that optimum dyeing condition is 400%(o.w.f.), $80^{\circ}C$, 60 min. And repeated dyeing improves dye uptake. Color fastness to dry cleaning and rubbing was good, but light fastness and perspiration fastness was not good. Blocking effect of ultraviolet radiation and deodorization efficiency was good.

• 대한화장품학회지
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• 제36권4호
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• pp.295-301
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• 2010

본 연구에서는 천연 추출물을 이용하여 화장품 원료를 개발하고자 다양한 천연물을 대상으로 조사하였고 그중 광나무 추출물을 선별하여 주름 개선 원료로 사용하고자 하였다. 고성능액체크로마토그래피를 수행하여 주름 개선 효과로 잘 알려진 oleanolic acid 31.06 %와 ursolic acid 8.92 %를 확인하였다. 제조된 광나무 추출물은 피부 섬유아세포에서 procollagen type I과 hyaluronan synthase-3의 발현을 증가시키고 matrix metalloproteinase (MMP)-1, MMP-2, cyclooxygenase-2의 발현을 감소시킬 뿐 아니라 elastase의 활성을 억제하여 주름 개선 기능을 갖는 것을 확인하였다. 따라서 광나무 추출물은 주름개선 화장품 소재로 개발될 수 있는 잠재력이 있다.

• 한국환경생태학회지
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• 제7권1호
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• pp.1-5
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• 1993

목본식물에 대한 Al독성에 관한 기초자료를 얻고자, Al농도별(1.0, 2.5및 5.0mM) 수용액과 대조구로 지하수를 모래를 채운 화분에 파종한 곰솔, 측백나무 및 쥐똥나무에 1993년 4월 28일부터 6월 16일까지 주 3회씩, 1회 5mm의 강도로 처리하였다. 6월 26일 묘목을 굴취하여 생장관련형질(묘목의 수, 묘고, 지상부, 지하부 및 개체당 건중량)을 측정하여 수종간, 처리간 비교하였다. Al수용액 처리에 대한 반응은 수종별로 상이하였으며, 쥐똥나무가 세 수종 중에서는 가장 감수성인 것으로 나타났으며, 곰솔이 가장 내성을 지닌 것이라 판단된다.

• Natural Product Sciences
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• 제24권2호
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• pp.93-98
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• 2018

Medicinal plants are potential sources of anticancer agents screening. A large number of phytochemicals, including triterpenoids, have been reported to have significant cytotoxic effects on cancer cells. From the fruits of Ligustrum japonicum Thunb., thirteen triterpenoids (1 - 13) were isolated and evaluated for their cytotoxic activity against Hela and HL-60 cells. As results, 8 (oleanolic acid) showed significant effects on Hela with $IC_{50}$ values of $5.5{\mu}M$, and moderate effects on HL-60 cells with $IC_{50}$ values of $55.9{\mu}M$. Meanwhile, 10 (oleanderic acid) and 11 ($3{\beta}$-acetoxy-urs-12-en-28-oic acid) exhibited moderate inhibitory effects on Hela with $IC_{50}$ value of 55.0 and $68.8{\mu}M$, respectively. Moreover, 10 showed cytotoxic effect on HL-60 cell line with $IC_{50}$ value of $63.9{\mu}M$. To our knowledge, this is the first report that oleanderic acid was isolated from L. japonicum and investigated in cytotoxic effects on Hela and HL-60 cells.

• Asian-Australasian Journal of Animal Sciences
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• 제20권9호
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• pp.1438-1443
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• 2007

The experiment was conducted to evaluate the effects of Ligustrum lucidum (LL) and Schisandra chinensis (SC) on the growth, antioxidative metabolism and immunity of laying strain male chicks. The results showed that diets supplemented with 1% of either LL or SC had no effects on the growth performance of chicks compared with the control. Furthermore, both LL and SC significantly reduced malondialdehyde (MDA) concentration of serum and heart of chicks (p<0.05). In addition, superoxide dismutase (SOD) activity of serum of the birds was significantly elevated by supplementation with SC (p<0.05). Glutathione reductase (GR) activity of heart and serum of the birds was significantly elevated by supplementation with LL or SC (p<0.05). LL supplementation significantly elevated antibody values against Newcastle Disease virus (NDV)(p<0.05) and lymphoblastogenesis (p<0.05) of the birds. The results suggest that diets supplemented with 1% of either LL or SC may improve immune function and antioxidant status of chicks.

• 대한한의학회지
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• 제17권2호
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• pp.227-236
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• 1996

The effect of Ligustrum Lucidum(LL) on the production of nitric oxide (NO) and superoxide by murine peritoneal macrophages were investigated. Stimulation of the cells with LL in the presence or absence of interferon-r(IFN-r) resulted in the increased accumulation of nitrite in the medium. To further examine the mechanism of LL induced. NO Synthesis, we evaluated the secretion of tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ by LL in murine macrophages. Treatment of LL increased the secretion of bioactive $TNF-{\alpha}$ in cultured medium. In addition, LL induced NO production was decreased by the treatment of anti-murine $TNF-{\alpha}$. neutralizing antibodies, indicating that LL induced superoxide production was decreased by the treatment of anti-murine $TNF-{\alpha}$ neutralizing antibodies. These data suggested that LL induced superoxide production was related to $TNF-{\alpha}$ secretion. In conclusion, our results indicates that LL may enhance innate immune response and be applied as a immunoregulating drug improving phagocytosis.

• 한국약용작물학회지
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• 제21권5호
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• pp.323-328
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• 2013

Traditionally, Ligustrum lucidum fruits (LL) is one of the well-known oriental herb used in the treatment of skin and lung inflammation. This study investigated anti-inflammatory effects of LL in the pathogenesis of acute pulmonary inflammation in mice. Acute pulmonary inflammation was induced by intratracheal instillation of cigarette smoke condensate (CSC) and lipopolysaccharide (LPS) 5 times within 12 days in mice. LL extract was administered orally at a dose of 50 or 200 mg/kg. Administration of LPS and CSC significantly elevated airway hyperresponsiveness (AHR) to mice, and increased in the levels of inflammatory cells and mediators in mice. However, the LL extract significantly reduced the elevated AHR, and the increase of neutrophils, $CD4^+/CD3^+$ cells and $CD8^+/CD3^+$ cells, along with reducing the expression of TNF-${\alpha}$, IL-6, and MIP-2. Moreover, the LL extract alleviated the infiltration of inflammatory cells in expanded airway walls histologically. These results indicate that the LL extract has an inhibitory effects on acute pulmonary inflammation and AHR in murine model, and plays a crucial role as a immunomodulator which possess anti-inflammatory property.

• 한국환경생태학회지
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• 제24권1호
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• pp.69-77
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• 2010

정도리 해안방풍림은 바다와 육지 사이에 위치하면서 육상 경작지나 어촌 마을을 보호하는 생태적 천이지역으로서 매우 중요한 곳이다. 정도리 방풍림 식생 중 해안가 갯돌밭 지역에서는 상동나무 망토군락을 이루며 그 안쪽에 광나무나 쥐똥나무가 아교목상으로 우점한다. 안쪽부분은 광나무-굴참나무군락, 광나무-덜꿩나무군락, 광나무-생달나무군락, 생달나무-개서나무군락 및 소나무-덜꿩나무군락으로 확인되었다. 정도리 방풍림은 교목층 평균수고는 10.3m, 평균흉고 직경은 30.3cm로 인공 숲이지만 자연림에 가까운 이차림으로 생태학적인 보전가치가 높다. 명송 3 호로 지정된 정도리 방풍림은 많은 방문객들로 안해 인위적인 간섭을 당할 가능성이 크다. 따라서 국립공원 관리공단에서는 정도랴 방풍림을 보전하기 위해 지속적인 유지관리를 해야 할 것이다. 그리고 정도리 구계등 갯돌의 문화적 가치와 숲의 자연성을 고려하여 장차 문화재청은 정도리 방풍림을 병승으로 뿐만 아니라 천연기념물로 지정하여 보전해야 할 것이다.

• 대한본초학회지
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• 제27권6호
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• pp.107-114
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• 2012

Objectives : In this study, we investigated the anti-diabetic and anti-inflammatory effects of water extract from leaves of Ligustrum japonicum (WLJ) in db/db mouse. Methods : The db/db mice were treated orally with WLJ (300 mg/kg/day) for 10 weeks to examine the long-term effects on hyperglycemia and glomerular tissue as well as biochemical and functional abnormalities in the kidney. Results : WLJ treatment markedly reduced plasma levels of glucose, triglyceride, creatinine, and systolic blood pressure in diabetic db/db mouse. Treatment of WLJ significantly increased plasma level of high density lipoprotein (HDL)-cholesterol. We also found that overexpressions of vascular cellular adhesion molecule (VCAM)-1 and endothelin (ET)-1 were observed in aortic tissue of db/db mouse, whereas, WLJ suppressed both expression of VCAM-1 and ET-1 in aorta. In renal tissue, overexpressions of ICAM-1 and TGF-${\beta}1$ were found in untreated db/db mouse, however, significantly decreased those levels by WLJ treatment. The insulin immunoreactivity of the pancreatic islets remarkably increased in WLJ treated db/db mouse compared with untreated db/db mouse. Taken together, WLJ treatment ameliorated hyperglycemia and hyperlipidemia via improvement of insulin secretion and lipid metabolism, respectively. Furthermore, WLJ treatment also ameliorated hypertension via inhibition of inflammatory process in vascular and renal tissues. Conclusions : Ligustrum japonicum has an anti-diabetic and anti-inflammatory effects in db/db mouse. Thus, these results suggested a beneficial effect of Ligustrum japonicum in treatment with diabetes and diabetic vasculopathy.