• Title/Summary/Keyword: Light tools

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Functional annotation of uncharacterized proteins from Fusobacterium nucleatum: identification of virulence factors

  • Kanchan Rauthan;Saranya Joshi;Lokesh Kumar;Divya Goel;Sudhir Kumar
    • Genomics & Informatics
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    • v.21 no.2
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    • pp.21.1-21.14
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    • 2023
  • Fusobacterium nucleatum is a gram-negative bacteria associated with diverse infections like appendicitis and colorectal cancer. It mainly attacks the epithelial cells in the oral cavity and throat of the infected individual. It has a single circular genome of 2.7 Mb. Many proteins in F. nucleatum genome are listed as "Uncharacterized." Annotation of these proteins is crucial for obtaining new facts about the pathogen and deciphering the gene regulation, functions, and pathways along with discovery of novel target proteins. In the light of new genomic information, an armoury of bioinformatic tools were used for predicting the physicochemical parameters, domain and motif search, pattern search, and localization of the uncharacterized proteins. The programs such as receiver operating characteristics determine the efficacy of the databases that have been employed for prediction of different parameters at 83.6%. Functions were successfully assigned to 46 uncharacterized proteins which included enzymes, transporter proteins, membrane proteins, binding proteins, etc. Apart from the function prediction, the proteins were also subjected to string analysis to reveal the interacting partners. The annotated proteins were also put through homology-based structure prediction and modeling using Swiss PDB and Phyre2 servers. Two probable virulent factors were also identified which could be investigated further for potential drug-related studies. The assigning of functions to uncharacterized proteins has shown that some of these proteins are important for cell survival inside the host and can act as effective drug targets.

The Impact of Leadership and Dynamic Capabilities on Firm Performance, Mediated by Digital Transformation - Aerospace & Defense Industry - (리더십과 동태적 역량이 디지털 전환을 매개로 기업성과에 미치는 영향 - 항공우주 및 방위산업을 중심으로 -)

  • Jin-Seog Kim;Ki-Woong Kim;Sung-Sik Park
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.31 no.3
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    • pp.133-141
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    • 2023
  • In the recent context of the Fourth Industrial Revolution, there is growing interest in digital transformation and smart factory as a focal point. But, the Aerospace and Defense (A&D) sector has seen limited research on digital transformation, primarily concentrating on digitally-driven areas. The study validates hypotheses pertaining to the factors that facilitate successful digital transformation within the A&D sector and the influence of digital leadership and dynamic capabilities, employing statistical tools like SPSS and AMOS. The comprehensive analysis reveals that, similar to manufacturing industries, digital leadership in A&D companies exerts an influence on successful digital transformation through dynamic capabilities. Furthermore, digital transformation within the A&D sector has a positive impact on firm performance. This paper offers empirical insights into digital transformation within the A&D sector, shedding light on how successful digital transformation can be achieved within the domestic A&D industry.

Effect of Importance of Selection Attributes on Satisfaction and Repurchase of Nostalgic Desserts among 20's

  • Choo Yeon KIM;Seunghyeon LEE;Seong Soo CHA
    • The Journal of Industrial Distribution & Business
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    • v.15 no.3
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    • pp.1-9
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    • 2024
  • Purpose: This research aimed at understanding the dynamics of consumer behavior in the context of nostalgic desserts. The primary objective is to scrutinize how different attributes like quality, health, convenience, and trend influence customer satisfaction and their subsequent decision to repurchase nostalgic desserts. Research Method: The study leverages structural equation modeling, incorporating statistical tools such as SPSS and AMOS for a thorough analysis. It involves collecting data over a specified period, followed by correlation and trend analyses to deduce patterns and relationships. Results: The findings reveal that attributes such as quality, health, convenience, and trend significantly impact customer satisfaction and repurchase intentions. Interestingly, economic factors appeared to have a negligible effect on these decisions. The study offers a comprehensive understanding of the factors that influence consumer decisions in the context of nostalgic desserts, providing valuable implications for both academic research and practical marketing strategies. Conclusions: The insights garnered from this research are pivotal for formulating marketing strategies for nostalgic dessert brands. It underscores the importance of accentuating quality, health, and trend in product offerings to boost customer satisfaction and encourage repurchases. The study also sheds light on the evolving nature of consumer preferences and the integral role of nostalgia in shaping purchasing behaviors.

Performance evaluation by simulation for the angular luminous intensity distributions of marine lanterns using a tilting aspherical Fresnel lens and a C-8 type light bulb (기울어진 비구면 프레넬 렌즈와 C-8 type 전구를 이용한 해상용 랜턴의 배광곡선 시뮬레이션을 통한 성능평가)

  • Cho Hyun Seok;Jo Jae Heung;Park Seungl Nam;Park Chul Woung;Kim Yong Wan;Kim Jong Tae
    • Korean Journal of Optics and Photonics
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    • v.15 no.6
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    • pp.511-518
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    • 2004
  • Providing marine signal lanterns with advantages of little weight as well as large aperture, a Fresnel lens has been adopted to transfer the beam from the lanterns up to 10 nautical miles (18.53 km). A Fresnel lens with the diameter of 250 mm and 300 mm was designed by a lens design program and optimized by adjusting the groove parameters of the lens. The angular luminous intensity distribution (ALID) of this lens was calculated by using an illumination analysis program considering the ALID of a light bulb. At the best alignment of the bulb, the maximum luminous intensities (MLI) of the lantern were 1000 cd (in the case of 250 mm diameter) and 1300 cd (in the case of 300 mm diameter). These are more than the critical value of 720 cd that is the Korean Standard of MLI for the marine lantern. The ALID was investigated as a function of misalignment from the lens focus to determine the tolerance of the alignment ranges.

LED Source Optimization for the LED Chip Array of the LED Luminaires (LED 조명기구에서 LED 칩 배치에 따른 광원 최적화)

  • Yoon, Seok-Beom;Chang, Eun-Young
    • Journal of Digital Convergence
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    • v.14 no.4
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    • pp.419-424
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    • 2016
  • In this paper, we studied a light distribution for the LED chips arrangement using an optical design software. The structures of the edge type LED luminaires are reflector plane, LGP(lighting guide plane) and diffuse plane. The reflector plane is on the middle of the overall structure. We had simulation that placing LED chips on the reflector center of the reflector edge by changing the position of LED chips above the reflector center at 1mm, 2mm, and 3mm respectively. In the case, when LED chips are on the center of the reflector, it shows the light distribution of the general diffuse illumination, the semi-direct distribution with 0.56 efficiency and the direct distribution with 0.31 efficiency. And the wedge type LGP shows more efficiency than the flat type. Gradually increasing shape of semi-spherical type by 0.015mm has power of 1.02W, efficiency of 0.25, and maximum luminous intensity of 0.104W/sr, it also and shows the better optical characteristics than the reflector plane that have no patterns. This semi-spherical type shows the better optical characteristics than the reflector plane that have no patterns.

A Study on the Development of Ultra-precision Small Angle Spindle for Curved Processing of Special Shape Pocket in the Fourth Industrial Revolution of Machine Tools (공작기계의 4차 산업혁명에서 특수한 형상 포켓 곡면가공을 위한 초정밀 소형 앵글 스핀들 개발에 관한 연구)

  • Lee Ji Woong
    • Journal of Practical Engineering Education
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    • v.15 no.1
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    • pp.119-126
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    • 2023
  • Today, in order to improve fuel efficiency and dynamic behavior of automobiles, an era of light weight and simplification of automobile parts is being formed. In order to simplify and design and manufacture the shape of the product, various components are integrated. For example, in order to commercialize three products into one product, product processing is occurring to a very narrow area. In the case of existing parts, precision die casting or casting production is used for processing convenience, and the multi-piece method requires a lot of processes and reduces the precision and strength of the parts. It is very advantageous to manufacture integrally to simplify the processing air and secure the strength of the parts, but if a deep and narrow pocket part needs to be processed, it cannot be processed with the equipment's own spindle. To solve a problem, research on cutting processing is being actively conducted, and multi-axis composite processing technology not only solves this problem. It has many advantages, such as being able to cut into composite shapes that have been difficult to flexibly cut through various processes with one machine tool so far. However, the reality is that expensive equipment increases manufacturing costs and lacks engineers who can operate the machine. In the five-axis cutting processing machine, when producing products with deep and narrow sections, the cycle time increases in product production due to the indirectness of tools, and many problems occur in processing. Therefore, dedicated machine tools and multi-axis composite machines should be used. Alternatively, an angle spindle may be used as a special tool capable of multi-axis composite machining of five or more axes in a three-axis machining center. Various and continuous studies are needed in areas such as processing vibration absorption, low heat generation and operational stability, excellent dimensional stability, and strength securing by using the angle spindle.

Research on Geometric Shape in the 20th Century Design Education - Focused on the relation of $Fr{\ddot{o}}bel$ Kindergarten Education - (20세기 디자인교육의 기하학적인 형태에 대한 탐구 - 프뢰벨 유치원 교육과의 연관성을 중심으로 -)

  • Bang, Kyung-Rhan
    • Archives of design research
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    • v.18 no.2 s.60
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    • pp.325-334
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    • 2005
  • The purpose of this thesis is to explore the fundamental reasons and general circumstances of the introduction of geometric shape to the 20th century's design education. The modern design education was directly influenced by the German Kindergarten Movement and its educational ideal, so they began to employ geometric shapes in visual education. When Friedrich Frobel, a professional German child educator of the 19th century, invented the 'Spielgaben,' it soon became a popular educational tool. It was a turning point in the child educational system, from then they began to actively employ 'tools' in art education. The Spielgaben was created based on the geometric principle of a popular block game of the 19th century. On the other hand, a game program called 'Bechaftigungsmaterial' led early Modernists to adopt geometric shape in their works. Then, geometric shape were applied to a primary educational program designed by the Bauhaus that gave birth to the Modern design education in the 20th century. likewise, the substantial reasons why the principles of point/line/plain and geometric shapes had been taken in the 20th century design education can be explained through this historical background. This research is to investigate how Kindergarten Movement and Modern design education can be associated with each other, particularly in the light of geometric elements. Therefore, I first referred to the historic records in order to reveal their relation, and then analyzed the similarities and differences between the two activities. In result, I could explore the relationship between child educational tools and the 20th century's design education.

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Effects of the Space in Image Equipment Characteristic (영상장치의 표현특성이 공간에 미치는 영향)

  • Yoo, Jae-Yeup
    • Proceedings of the Korea Society of Design Studies Conference
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    • 2004.05a
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    • pp.44-45
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    • 2004
  • With the development of informational machinery and tools in the modern industrial society, the image is expressed diversely as tools of informational transmission and artistic communication. This image is revival equipment and transmissional media in which sound and light are comprehensively formed. The image's intuitive and sensational expressivity can revive subjects and express a fiction, a reality, a nonfiction, and a virtual reality as a communication tool that has synchronicity and the medium of meaning. Because of this, the domain of the image will be gradually extended in the future, and the world of cognizance that can be detected across our living space will absorb the image diversely and react. In this context, the investigator examined what influence image media and equipments have in space as spatial equipments, based on the recognition of cerrelation among the image, space, and mankind, namely, the environmental meaning the mage and the space contain. Therefore, this study was conducted from the aspects of relationship establishment between image equipments that are ever expansive to a variety of domains and the space that accommodates the equipments. As study findings, the influences the image equipments have on space and their expressional features are presented in three aspects: 'the expressional medium of mutual synergy','metaphysical ultra-epithelial space constituent',' and 'object'. This study seems to be meaningful in that we can expect the spatial approach method by purposes and spatial layout of image structures, with this study, through analyzing the meaning of relationship between image equipments and space.

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The Classifying Ability of the Igneous Rocks with Naked Eyes for Preservice Science Teachers (예비과학교사들의 화성암 육안분류 능력)

  • Moon Byoung Chan;Jeong Jin-Woo;Chung Chull Hwan
    • Journal of the Korean earth science society
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    • v.26 no.7
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    • pp.630-639
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    • 2005
  • The purpose of this study was to investigate the classifying ability of the igneous rocks with the naked eye for 36 preservice science teachers. For this, we selected six specimens of igneous rocks that consisted of rhyolite, andesite, basalt, granite, diorite, and gabbro, and performed the questionnaire with them. Preservice science teachers needed the average of 3 tools to classify the rocks. Most of the selected tools were loupe, streak plate, hammer and Mohs’ hardness scale. Many preservice science teachers selected basalt and granite samples to classify igneous rocks among 6 kinds of the rocks which were exhibited. However, the results of the identification with the naked eye showed that the right answer rate was significantly different based on what rock sample had been selected. Nobody gave the right answer among 10 students who chose the rhyolite sample, but all of 36 students who picked the basalt sample answered correctly. And $62\%$ of 8 students who chose the andesite sample, 62% of 32 student choosing granite, $7\%$ of 13 students choosing diorite and $44\%$ of 9 students choosing gabbro were correctly answered. In identifying igneous rock samples with the naked eye, most subjects relied on vesicular texture to basalt, and they used textural, color and empirical characters to granite. But, some felt more or less difficulty to distinguish between intermediate and light colors and to recognize porphyry.

Guidelines for big data projects in artificial intelligence mathematics education (인공지능 수학 교육을 위한 빅데이터 프로젝트 과제 가이드라인)

  • Lee, Junghwa;Han, Chaereen;Lim, Woong
    • The Mathematical Education
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    • v.62 no.2
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    • pp.289-302
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    • 2023
  • In today's digital information society, student knowledge and skills to analyze big data and make informed decisions have become an important goal of school mathematics. Integrating big data statistical projects with digital technologies in high school <Artificial Intelligence> mathematics courses has the potential to provide students with a learning experience of high impact that can develop these essential skills. This paper proposes a set of guidelines for designing effective big data statistical project-based tasks and evaluates the tasks in the artificial intelligence mathematics textbook against these criteria. The proposed guidelines recommend that projects should: (1) align knowledge and skills with the national school mathematics curriculum; (2) use preprocessed massive datasets; (3) employ data scientists' problem-solving methods; (4) encourage decision-making; (5) leverage technological tools; and (6) promote collaborative learning. The findings indicate that few textbooks fully align with these guidelines, with most failing to incorporate elements corresponding to Guideline 2 in their project tasks. In addition, most tasks in the textbooks overlook or omit data preprocessing, either by using smaller datasets or by using big data without any form of preprocessing. This can potentially result in misconceptions among students regarding the nature of big data. Furthermore, this paper discusses the relevant mathematical knowledge and skills necessary for artificial intelligence, as well as the potential benefits and pedagogical considerations associated with integrating technology into big data tasks. This research sheds light on teaching mathematical concepts with machine learning algorithms and the effective use of technology tools in big data education.