• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
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• pp.480-480
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• 2007

This paper performed the basic study for developing the light therapy equipment for medical treatment. We developed the equipment for medical therapy using a high brightness LED. This equipment was fabricated using a micro-controller and a high brightness LED, and designed to enable us to control light irradiation time, intensity, frequency and so on. Especially, to control the light irradiation frequency, and to control the change of output value, TLC5941 was used. Control stage is divided into 4 step by program. Consequently, the current value could be controlled by the change of level in Continue Wave(CW) and the output of a high brightness LED could be controlled, stage by stage.

• 대한방사성의약품학회지
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• 제9권1호
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• pp.35-41
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• 2023

Photodynamic therapy (PDT), in which a photosensitizer (PS), light, and molecular oxygen are essential components, is a non-invasive and highly effective cancer therapeutic method. However, PDT suffers from the penetration limit of light caused by attenuation and scattering of light through tissues constraining its use to skin and endoscopically accessible cancers. Cerenkov luminescence (CL) is defined as the light illuminated when charged particles move in a dielectric medium at a velocity greater than the phase velocity of light. It is known that medical radioisotopes in preclinical and clinical settings have enough energy to generate CL, and lately, CL has been exploited as an excitation source for PDT without external light illumination. This review introduces state of the art studies of radioisotope-based PDT for cancer, in which radioisotopes are utilized as a light source.

• 한국전기전자재료학회논문지
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• 제20권12호
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• pp.1087-1092
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• 2007

We developed the 4-channel Light Medical Therapy Apparatus for Skin Injury Cure using a high brightness LED. This equipment was fabricated using a micro-controller and a high brightness LED, and designed to enable us to control light irradiation time, intensity and reservation. In this paper, the designed device was used to find out how high brightness LED light affects the skin injury of SD-Rat(Sprague-Dawley Rat). In the experiment, $1\;cm^2$ wounds on the skin injury of SD-Rat(Sprague-Dawley Rat) were made. Light irradiation group and none light irradiation group divided, each group was irradiated one hour a day for 14 days. In result, compared with none light irradiation group, the lower incidence of inflammation and faster recovery was shown in light irradiation group.

• 한국전기전자재료학회논문지
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• 제20권8호
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• pp.731-735
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• 2007

We developed the 4channel Light Medical Therapy Apparatus for External Injury Cure using a high brightness LED. This equipment was fabricated using a micro-controller and a high brightness LED, and designed to enable us to control light irradiation time, intensity, frequency and so on, Especially, to control the light irradiation frequency, FPGA was used, and to control the change of output value, TLC5941 was used. Control stage is divided into 4 levels by program. Consequently, the current value could be controlled by the change of level in Continue Wave(CW) and the output of a high brightness LED could be controlled stage by stage. Compared with one LED irradiation, several LEDs irradiation could increase optical power.

• 수면정신생리
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• 제10권1호
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• pp.20-25
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• 2003

Many people suffer from chronic insomnia. Inappropriate sleep causes attention difficulties, decreased work efficiency, and increased traffic accidents and disasters. Evaluating the precise causes of insomnia prior to treatment is very important, because chronic insomnia can be a secondary symptom of other medical, psychiatric, and sleep disorders. Medication and behavior therapy are not exclusive of each other, and both treatments are beneficial to some patients, but currently many physicians and patients tend to be dependent only on medication. While long-term medication causes various degrees of dependency, tolerance, and withdrawal symptoms, behavior therapy has a stable effect over a long period. Behavior therapy is one of the most important treatment modalities for chronic insomnia. It shortens sleep latency, and decreases frequency of awakening during sleep. The rationale and practice of currently used behavior therapy and light therapy will be reviewed in this study.

• 한국정보통신학회논문지
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• 제22권9호
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• pp.1237-1242
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• 2018

광 역학 치료법은 그 효과가 특정 위치의 암세포에 국한되어있어 주변의 정상 세포에 큰 영향을 미치지 않기 때문에 다양한 부작용이 존재하는 현재의 암 치료법의 대안으로 제안되어 왔다. 이러한 광 역학 치료에는 광감응제를 선택적으로 자극시키기 위해 레이저를 이용하고 있으나, 고가의 치료비용과 높은 발열현상으로 사용에 제한적이다. 그러나 다양한 파장의 빛을 발할 수 있는 소형 발광 다이오드가 저가로 개발됨에 따라 대체가 가능하며, 이는 광 역학 치료 장비의 소형화 및 저가의 치료 장비 개발에 큰 영향을 미치고 있다. 현재 활발하게 연구되는 광 역학 치료법은 다양한 광감응제를 이용하여 암세포의 사멸을 유도하는데 목적이 있으나, 특정한 파장을 중심으로 진행된 연구는 상대적으로 미비한 실정이다. 따라서 본 논문에서는 저렴하며, 발열현상이 작고, 다양한 파장대의 광원지원이 가능한 발광 다이오드를 사용하고 이를 아두이노로 제어하여 새로운 저가의 암세포 증식 억제 모듈을 개발함으로써, 그 효과를 정량적으로 분석하고 새로운 항암치료법을 제시하고자 한다.

• 수면정신생리
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• 제5권2호
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• pp.202-209
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• 1998

Authors report the findings of nocturnal polysomnography and multiple sleep latency test(MSLT) before and after morning light treatment in a winter depressive patient with hypersomnia. On polysomnographic recordings, the sleep pattern of this case before light treatment was similar to that of narcolepsy exhibited, sleep onset REM period(SOREMP). After treatment, the shortened REM latency changed to normal condition, but, deep sleep percentage did not changed, and stage 4 sleep percentage was decreased. Depressive symptoms were improved on clinical interview with Hamilton Depressive Rating Scale. Sleep log showed shortened sleep latency and reduced sleep duration. These findings suggest that although light treatment could alter the sleep structure in seasonal affective disorder with hypersomnia, it does not necessarily imply that antidepressant response of light treatment is result of change of sleep structure.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 추계학술대회 논문집 Vol.21
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• pp.416-417
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• 2008

This paper performed the basic study for developing the Photodynamic Therapy Equipment for medical treatment. We developed the 4channel light medical therapy apparatus for external injury cure using a LED light source. This equipment was fabricated by using microcontroller, and designed to enable us to control light irradiation timer, intensity and reservation. In this paper, the designed device was used to find out how 470nm LEDs light source affects the skin wound of RAT. In the experiment, $1cm_2$ wounds on the External injury of RAT were made. Light irradiation RAT and none light irradiation RAT divided, each RAT was irradiated one hour a day for 15 days. In result, compared with none light irradiation RAT, the lower incidence of inflammation and faster recovery was shown in light irradiation RAT.

• Journal of the Optical Society of Korea
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• 제17권2호
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• pp.205-212
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• 2013

Pain is one of the quite common symptoms in clinics and many treatment methods have been applied to relieve pain. Among the treatments, high-intensity light therapy for pain has been introduced, but this therapy has not been fully supported by confirmed efficacy due to the absence of quantitative assessments and treatment feedback data in real time. In this study, the evaluation of light distribution in tissue was performed with current high-intensity light sources quantitatively using light-tissue interaction simulations. The diffuse reflectance in tissue was generated using Monte Carlo simulation that traces photons as they undergo multiple scattering and absorption within each tissue layer (skin, fat, and muscle) and within multi-layered tissue. The results showed that the highest diffuse reflectance and the deepest penetration of tissue were achieved at ${\lambda}$=830 nm when compared with other wavelengths like ${\lambda}$=650 nm, 980 nm and 1064 nm.

• Medical Lasers
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• 제10권1호
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• pp.15-21
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• 2021

As technology advances at a rapid rate, innovations in regenerative medicine will eventually include the use of energy-based therapeutics, such as low intensity-pulsed ultrasound stimulation (LIPUs), pulsed electromagnetic field stimulation (PMFs), and low-level laser/light therapy (LLLt) or photobiomodulation therapy (PBMt). Among these treatments, LLLt/PBMt attracted significant attention by the turn of the century, as evidenced by the numerous publications compared to LIPUs and PMFs, particularly for augmented bone regeneration (ABR). This is a testament of how the maturation of technology and scientific knowledge leads to latent compounded applications, even when the value of a technique is reliant on empirical data. This article reviews some of the notable investigations using LLLt/PBMt for bone regeneration published in the past decade, focusing on how this type of therapy has been utilized together with the existing regenerative medicine landscape.