• Investigative Magnetic Resonance Imaging
• /
• v.25 no.4
• /
• pp.218-228
• /
• 2021

Due to their high degree of freedom to transfer and acquire light, fiber optics can be used in the presence of strong magnetic fields. Hence, optical sensing and imaging based on fiber optics can be integrated with magnetic resonance imaging (MRI) diagnostic systems to acquire valuable information on biological tissues and organs based on a magnetic field. In this article, we explored the combination of MRI and optical sensing/imaging techniques by classifying them into the following topics: 1) functional near-infrared spectroscopy with functional MRI for brain studies and brain disease diagnoses, 2) integration of fiber-optic molecular imaging and optogenetic stimulation with MRI, and 3) optical therapeutic applications with an MRI guidance system. Through these investigations, we believe that a combination of MRI and optical sensing/imaging techniques can be employed as both research methods for multidisciplinary studies and clinical diagnostic/therapeutic devices.

• Journal of Information Display
• /
• v.11 no.3
• /
• pp.100-108
• /
• 2010

A multi-user autostereoscopic display based on laser scanning is described in this paper. It does not require the wearing of special glasses; it can provide 3D to several viewers who have a large degree of freedom of movement; and it requires the display of only a minimum amount of information. The display operates by providing regions in the viewing field, referred to as "exit pupils," which follow the positions of the viewers' eyes under the control of a multi-user head tracker. The display incorporates an RGB laser illumination source that illuminates a light engine. The light directions are controlled by a spatial light modulator, and a front screen assembly incorporates a novel Gabor superlens. Its operating principle is explained in this paper, as is the construction of three iterations of the display. Finally, a method of developing the display into one that is suitable for television applications is described.

• The Bulletin of The Korean Astronomical Society
• /
• v.26 no.2
• /
• pp.54.1-54.1
• /
• 2001

• Progress in Medical Physics
• /
• v.9 no.2
• /
• pp.105-113
• /
• 1998

Accurate radiation dosimetric characters is very important to determine of dose to a radiotherapeutic patient. Medical linear accelerators have been developed not only its new quality of convenient operation but also electric moderation. It is reliable to measure more detail physical parameter that linac's internal ability. Typically, radiation dosimetric tool is classified ionization chamber, film, thermoluminescence dosimeter, etc. Nowaday, Electronic Portal Imaging Device is smeared in radiation field to verification of treatment region. EPID's image was focused that using both on-line image verification and absolutely minimum absorbed dose during radiotherapy. So, Electronic Portal Imaging was tested for quality evaluation of medical linear accelerator had its pure conditional flash. This study has performed symmetry, Light/Radiation field congruence, and energy check, geometry difference on wedge filter using a liquid filled ion chamber (EPID). Prior to irradiated on EPID, high energy photon beam is checked with ion chamber. Using these results more convenient dosimetric method is accomplished by EPID that taken digital image. Medical image is acquired with EPID too. Therefore, EPID can be analyzed by numerical information for what want to see or get more knowledge for natural human condition.

• Journal of the Optical Society of Korea
• /
• v.20 no.1
• /
• pp.101-106
• /
• 2016

A pupil filter is a useful technique for modifying the light intensity distribution near the focus of an optical system to realize depth of field (DOF) extension and superresolution. In this paper, we proposed a new design of the phase only pupil filter by using Zernike polynomials. The effect of design parameters of the new filters on DOF extension and superresolution are discussed, such as defocus Strehl ratio (S.R.), superresolution factor (G) and relative first side lobe intensity (M). In comparison with the other two types of pupil filters, the proposed filter presents its advantages on controlling both the axial and radial light intensity distribution. Finally, defocused imaging simulations are carried out to further demonstrate the effectiveness and superiority of the proposed pupil filter on DOF extension and superresolution in an optical imaging system.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.17 no.2
• /
• pp.576-590
• /
• 2023

Machine learning is widely used in various academic fields, and recently it has been actively applied in the medical research. In the medical field, machine learning is used in a variety of ways, such as speeding up diagnosis, discovering new biomarkers, or discovering latent traits of a disease. In the respiratory field, a relative regional air volume change (RRAVC) map based on quantitative inspiratory and expiratory computed tomography (CT) imaging can be used as a useful functional imaging biomarker for characterizing regional ventilation. In this study, we seek to predict RRAVC using various regular machine learning models such as extreme gradient boosting (XGBoost), light gradient boosting machine (LightGBM), and multi-layer perceptron (MLP). We experimentally show that MLP performs best, followed by XGBoost. We also propose several relative coordinate systems to minimize intersubjective variability. We confirm a significant experimental performance improvement when we apply a subject's relative proportion coordinates over conventional absolute coordinates.

• Journal of the Korea Computer Graphics Society
• /
• v.29 no.3
• /
• pp.13-19
• /
• 2023

카메라 센서의 한계로 인하여 촬영 장면에 따라 한 번의 촬영으로 모든 영역의 밝기가 적절하게 촬영되지 않는 경우가 존재한다. 이러한 센서의 한계는 하이 다이나믹 레인지 이미징 기술을 통해서 극복이 가능하다. 한 장면을 다양한 노출 설정으로 여러 번 촬영하는 브라케팅은 움직이는 피사체를 찍기에 적절하지 않으며 촬영 시간이 길다는 단점이 있다. 본 연구는 한 번의 촬영으로 서로 다른 노출의 이미지를 얻을 수 있는 소형 라이트필드 카메라를 제안한다. 라이트필드 카메라는 대표적으로 두 가지 형태가 있는데, 첫 번째는 여러 대의 카메라를 어레이로 배치한 라이트필드 카메라 시스템이며, 두 번째는 대물렌즈 뒤에 마이크로 렌즈 어레이를 배치한 카메라이다. 본 연구에서 제작된 초박형 라이트필드 카메라는 센서 위에 마이크로 렌즈어레이가 부착되어있는 형태의 카메라로 각 렌즈 조리개 크기를 다르게 설계하여 한 번의 촬영으로 다른 노출의 촬영 결과를 얻을 수 있게 설계되었다. 촬영된 단일 영상들을 전처리 하여 이미지 품질을 높인 이후, HDR 알고리즘을 통해 각 단일 이미지들보다 다이나믹 레인지가 넓은 이미지를 획득하도록 구현하였다. 또한 노출 시간을 기준으로 설계된 식을 수정하여 조리개값에 따라 다른 가중치를 둘 수 있도록 바꾸었고, 이를 통해 단 한 번의 촬영을 통한 HDR 이미징을 구현하였다.

• Nuclear Engineering and Technology
• /
• v.54 no.7
• /
• pp.2592-2598
• /
• 2022

Research groups in the field of PET instrumentation are studying time-of-flight(TOF) technology to improve the signal-to-noise ratio of PET images. Scintillation light transport and collection plays an important role in improving the coincidence resolving time(CRT) of PET detector based on a pixelated crystal array. Four crystal arrays were designed by the different optical reflection configuration such as external reflectors and surface treatment on the CRT and compared with the light output, energy resolution and CRT. The design proposed in the study was composed of 8 × 8 LYSO crystal array consisted of 3 × 3 × 15 mm³ pixels. The entrance side was roughened while the other five surfaces were polished. Four sides of all crystal pixels were wrapped with ESR-film, and the entrance surface was covered by Teflon-tape. The design provided an excellent timing resolution of 210 ps and improved the CRT by 16% compared to the conventional method using a polishing treatment and ESR-film. This study provided a method for improving the light output and CRT of a pixelated scintillation crystal-based brain TOF PET detector. The proposed configuration might be an attractive detector design for TOF brain PET requiring fast timing performance with high cost-effectiveness.

• Current Optics and Photonics
• /
• v.6 no.4
• /
• pp.420-429
• /
• 2022

In this paper, the details and design process of an optical system for space target detection cameras are introduced. The whole system is divided into three structures. The first structure is a short-focus visible light system for rough detection in a large field of view. The field of view is 2°, the effective focal length is 1,125 mm, and the F-number is 3.83. The second structure is a telephoto visible light system for precise detection in a small field of view. The field of view is 1°, the effective focal length is 2,300 mm, and the F-number is 7.67. The third structure is an infrared light detection system. The field of view is 2°, the effective focal length is 390 mm, and the F-number is 1.3. The visible long-focus narrow field of view and visible short-focus wide field of view are switched through a turning mirror. Design results show that the modulation transfer functions of the three structures of the system are close to the diffraction limit. It can further be seen that the short-focus wide-field-of-view distortion is controlled within 0.1%, the long-focus narrow-field-of-view distortion within 0.5%, and the infrared subsystem distortion within 0.2%. The imaging effect is good and the purpose of the design is achieved.

• Journal of the Optical Society of Korea
• /
• v.19 no.5
• /
• pp.487-493
• /
• 2015

A wavefront coding (WFC) technique provides an extension of the depth of field for a microscopy imaging system with slight loss of image spatial resolution. Through the analysis of the relationship between the incidence angle of light at the phase mask and the system pupil function, a mixing symmetrical cubic phase mask (CPM) applied to 5X-40X micro-objectives is optimized simultaneously based on point-spread function (PSF) invariance and nonzero mean values of the modulation transfer function (MTF) near the spatial cut-off frequency. Optimization results of the CPM show that the depth of field of these micro-objectives is extended 3-10 times respectively while keeping their resolution. Further imaging simulations also prove its ability in enhancing the defocus imaging.