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The Scattering Beam Measurement of the RBC and the Fabrication of the Micro Cell Biochip (적혈구의 산란빔 측정과 마이크로 세포 분석 바이오칩 제작)

  • Byun, In Soo;Kwon, Ki Jin;Lee, Joon Ha
    • Progress in Medical Physics
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    • v.25 no.2
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    • pp.116-121
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    • 2014
  • Next future, The bio technology will be a rapidly developing. This paper is the scattering beam measurement of the red blood cell (RBC) and the fabrication of the micro cell biochip using the bio micro electro mechanical system (Bio-MEMS) process technology. The Major process method of Bio-MEMS technology was used the buffered oxide etchant (BOE), electro chemical discharge (ECD) and ultraviolet sensitive adhesives (UVSA). All experiments were the 10 times according to the process conditions. The experiment and research are required the ultraviolet expose, the micro fluid current, the cell control and the measurement of the output voltage Vpp (peak to peak) waveform by scattering angles. The transmitting and receiving of the laser beam was used the single mode optical fiber. The principles of the optical properties are as follows. The red blood cells were injected into the micro channel. The single mode optical fiber was inserting in the guide channel. The He-Ne laser beam was focusing in the single mode optical fiber. The transmission He-Ne laser beam is irradiating to the red blood cells. The manufactured guide channel consists of the four inputs and the four outputs. The red blood cell was allowed with the cylinder pump. The output voltage Vpp waveform of the scattering beam was measured with a photo detector. The receiving angle of the output optical fiber is $0^{\circ}$, $5^{\circ}$, $10^{\circ}$, $15^{\circ}$. The magnitude of the output voltage Vpp waveform was measured in the decrease according to increase of the reception angles. The difference of the output voltage Vpp waveform is due differences of the light transmittance of the red blood cells.

The Development of Confocal Microscopy Using the Amplified Double-compound Flexure Guide (레버 증폭 구조의 플렉서를 이용한 공초점 현미경의 개발)

  • Lee, Sang-Won;Kim, Wi-Han;Jung, Young-Dae;Park, Min-Kyu;Kim, Jee-Hyun;Lee, Sang-In;Lee, Ho
    • Korean Journal of Optics and Photonics
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    • v.22 no.1
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    • pp.46-52
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    • 2011
  • A confocal microscope was developed utilizing a scanning sample stage based on a home-built double-compound flexure guide. A scanning sample stage with nano-scale resolution consisted of a double leaf spring based flexure, a displacement amplifying lever, a Piezo-electric Transducer(PZT) actuator and capacitance sensors. The performance of the two-axis stage was analyzed using a commercial finite element method program prior to the implementation. A single line laser was employed as the light source along with the Photo Multiplier Tube(PMT) that served as the detector. The performance of the developed confocal microscope was evaluated with a mouse ear skin imaging test. The designed scanning stage enabled us to build the confocal microscope without the two optical scanning mirror modules that are essential in the conventional laser scanning confocal microscope. The elimination of the scanning mirror modules makes the optical design of the confocal microscope simpler and more compact than the conventional system.

Evaluation of luminance performance of scintillating film for monitoring the position of a radioactive source in an NDT apparatus (비파괴검사 장치 내 방사선원 위치감시용 섬광필름의 발광성능 평가)

  • Lee, Kyung-Jin;Yun, Jeong-Ick;Park, Byung-Gi;Kim, Sin;Lee, Bong-Soo
    • Journal of radiological science and technology
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    • v.28 no.1
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    • pp.13-17
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    • 2005
  • In domestic nondestructive testing(NDT) field, there have recently been radiation exposure accidents due to a disregard for confirmation of the position of radioisotope during the test. In order to prevent these kinds of accidents, a scintillating film has been developed. The scintillating film that can convert gamma-ray to visible light has a function of the position detection of radioisotope in a opaque guide tube of an NDT apparatus. The aim of this study is to enhance the visibility performance of the scintillating film and find out the best configuration of the scintillating film. In order to find appropriate materials for the scintillating film, various inorganic scintillating materials were evaluated in this work. An absolute luminance of the scintillating films was measured by luminance meter for evaluation of visibility performance. Ir-192 gamma projector was used for NDT apparatus. The experiment shows that the scintillating film with reflective layer was the more effective performance for visibility. The higher mixing ratio of scintillating material to binding material, the higher luminance was measured. $Gd_2O_2S(Tb)$ inorganic powder as the scintillating materials had the best performance for visibility of the scintillating film. The developed scintillating film helps to ensure safer environment to the operators.

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Necessity of revision of the mandatory medication guidance regulation under the Pharmaceutical Affairs Act (약사법상 복약지도의무 규정의 개정 필요성)

  • Dawoon Jung
    • The Korean Society of Law and Medicine
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    • v.24 no.2
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    • pp.119-145
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    • 2023
  • The Pharmaceutical Affairs Act stipulates medication counseling as an obligatory requirement in the case of preparation of medicine. In fact, there are many cases where pharmacists only tell patients the dose and time and do not properly guide them on taking medications. However, in light of the current situation where non-face-to-face treatment is being attempted, there is a high possibility of drug-taking accidents due to insufficient medication guidance. In addition, as an aging society progresses, the need for explanations on pharmaceuticals is increasing. If a pharmacist causes damage to a patient by failing to give appropriate medication guidance, the patient can claim compensation for damages. In addition, if a drug accident occurs due to a conflict between the pharmacist's duty to guide medication and the doctor's duty to explain, a joint tort is established between the pharmacist and the doctor. Nevertheless, there are cases in which only doctors are judged to bear the tort liability. However, the Pharmaceutical Affairs Act includes providing information for the selection of over-the-counter drugs in the medication guidance as part of the medication guidance obligation. Therefore, in order to reconsider the importance of the medication-taking guidance duty, it is necessary to define the medicationaking information provision method and the medication-taking guidance duty as separate concepts. In addition, it is necessary to amend related regulations centered on patients so that medication guidance, such as side effects of medicines and interactions with concomitant medications, can be made in detail.

A Strategy for Attracting Chinese Food Tourists (음식을 활용한 중국인 관광객 유치전략)

  • Doh, Kyung Rok;Park, Duk Byeong
    • Journal of Agricultural Extension & Community Development
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    • v.20 no.4
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    • pp.1079-1103
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    • 2013
  • This study is to identify different characteristics of chinese tourists in relation to food tourism. These features includes motivation, travel behavior, attributions, information source, preference about local food and food tourism. Based on the results from empirical investigation, it develop suggestions for attracting chinese tourism to rural area. The results shows that the strongest motivation is to find new food which is different from daily life. Also, they believed that eating local food is meaningful travel behavior. In addition, this study reveals that the attribution of food selection is highly related to freshness, tastes, and sanitation. Accordingly, this study suggests following guide to attract chinese tourist to rural area. 1) developing unique and authentic local food, 2) preparing extensive menu with meat and local agricultural products & a light menu for breakfast 3) deliberating about freshness and sanitation, 4) creating good appearance and smell.

A Study on Beverage Consumption Pattern Associated with Food and Nutrient Intakes of College Students (대학생의 음료섭취 실태와 식품섭취 및 영양소섭취와의 관련성에 관한 연구)

  • Park, Myeong-Hui;Choe, Yeong-Seon;Jo, Seong-Hui;Ha, Tae-Seon
    • Journal of the Korean Dietetic Association
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    • v.5 no.1
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    • pp.21-28
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    • 1999
  • This study was conducted to investigate beverage consumptions in relation to food intakes of Korean young people. One hundred thirty five college students(61 males and 74 females) living in Taegu, Kyung-buk and Taejon answered to questionnaires and recorded three day food intakes between May 20 and June 5, 1997. The preferred beverages were fruit juice, carbonated drink, dairy drink, sport beverage for male students, and fruit juice, dairy drink, sport beverage and carbonated drink for female students. Beverage taken most frequently was coffee for both. Frequent consumption of orange juice was associated with consumption of vegetables, meats, and fats and oils used for frying, and light cola seemed to be consumed with greasy dishes. Beverage consumption contributed to intakes of calcium and vitamin $B_2$more than other nutrients. 4.6% of total energy intake, 15.5% of calcium intake, 11.4% of vitamin $B_2$ provided from beverages in female. Contributions of beverages to nutrient intakes were higher in female than in male students. Calcium intake was the lowest among nutrients for males, and intakes of iron and vitamin A were the lowest for females as compared to the recommended dietary allowances. Therefore it is necessary to guide college students to choose beverages for balanced intakes of necessary nutrients.

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Discrimination of Underground Explosions from Microearthquakes through the Pure-Continental Path (순수 대륙 경로에서 미소지진과 지하 인공폭발의 구별)

  • 김소구
    • The Journal of Engineering Geology
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    • v.4 no.1
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    • pp.29-42
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    • 1994
  • Discrimination studies between microearthquakes and underground explosions are carried out in the pure-continental path of north-south within the Korean Peninsula. The characteristic waveforms for explosions and microearthquakes are investigated in the light of observation and synthetic seismograms. The characteristic waveform generation is minnly a function of source mechanism and ray-path and former influences more strongly than the latter.A double-couple source mechanism for microeatthquakes and a single-couple(force) mechanism for explosions are presented in this study. It is found for very shallow events to have outstanding of $L_g$ waves in the transverse components that pass through the upper crust with period of 1 - 6 seconds and fundamental modes of Rayleigh waves, $R_g$ in the vertical component with period 8-12 seconds. Furthermore it is pointed out that the first arrival amplitudes of SH waves for explosions are always srnall regardless of azimuth of stations since there is non-existence of nodal lines for the explosion mechanism. Theoretical seismograms for explosions show the first motions of compression with short wavelengths as well as mostly fundamental modes of Rayleight waves, $R_g$ waves and $L_g$ waves, whereas those of micro-earthquakes give either compression or dilatation according to the ack azimuth epicenter to stations and poor or non $R_g$ waves and complicated $L_g$ waves, depending on the focal depth.

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Mechanism of Micro-V Grooving with Single Crystal Diamond Tool (단결정 다이어몬드 공구를 이용한 Micro-V 홈 가공기구)

  • Park D.S.;Seo T.I.;Kim J.K.;Seong E.J.;Han J.Y.;Lee E.S.;Cho M.W.;Choi D.S.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.1223-1227
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    • 2005
  • Fine microgroove is the key component to fabricate micro-grating, micro-grating lens and so on. Conventional groove fabrication methods such as etching and lithography have some problems in efficiency and surface integrity. This study deals with the creation of ultra-precision micro grooves using non-rotational diamond tool and CNC machining center. The shaping type machining method proposed in the study allows to produce V-shaped grooves of $40\mu{m}$ in depth with enough dimensional accuracy and surface. For the analysis of machining characteristics in micro V-grooving, three components of cutting forces and AE signal are measured and processed. Experimental results showed that large amplitude of cutting forces and AE appeared at the beginning of every cutting path, and cutting forces had a linear relation with the cross-sectional area of uncut chip thickness. From the results of this study, proposed micro V-grooving technique could be successfully applied to forming the precise optical parts like prism patterns on light guide panel of TFT-LCD.

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Effective expression of the caustic effect in 3D animation (3D Animation에서 효과적인 Caustic표현 연구)

  • 이순영;최유미
    • Proceedings of the Korea Contents Association Conference
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    • 2003.05a
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    • pp.132-138
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    • 2003
  • The caustic effect provides some of the most amazing indirect illuminated light patterns or scenery one could find in nature. We can perceive this in forms of twinkling stars, shimmering, visually deflected spoon in the water and other various occasions. To generate the caustic effect more realistic and effectively in 3D animation the understanding of the caustic effect and its application is very crucial. However, thor exists various factors in creating the caustic effect other than two main factors discussed in this paper and these factors will require to be studied and tested. In this report, various cases, which used the caustic effect to create more realistic scenery are studied and the role of the caustic effect played in various sceneries are analyzed. In addition to these case studies it is also experimented with changes in different conditions On the basis of the result of case studies, the report demonstrates how the caustic effect can be used to create more realistic scenery by conducting substantiate experiment and research on practicing 3D animation. With all of these researches, the paper is to present the education guide to produce more realistic scenery in 3D animation.

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3D LIDAR Based Vehicle Localization Using Synthetic Reflectivity Map for Road and Wall in Tunnel

  • Im, Jun-Hyuck;Im, Sung-Hyuck;Song, Jong-Hwa;Jee, Gyu-In
    • Journal of Positioning, Navigation, and Timing
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    • v.6 no.4
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    • pp.159-166
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    • 2017
  • The position of autonomous driving vehicle is basically acquired through the global positioning system (GPS). However, GPS signals cannot be received in tunnels. Due to this limitation, localization of autonomous driving vehicles can be made through sensors mounted on them. In particular, a 3D Light Detection and Ranging (LIDAR) system is used for longitudinal position error correction. Few feature points and structures that can be used for localization of vehicles are available in tunnels. Since lanes in the road are normally marked by solid line, it cannot be used to recognize a longitudinal position. In addition, only a small number of structures that are separated from the tunnel walls such as sign boards or jet fans are available. Thus, it is necessary to extract usable information from tunnels to recognize a longitudinal position. In this paper, fire hydrants and evacuation guide lights attached at both sides of tunnel walls were used to recognize a longitudinal position. These structures have highly distinctive reflectivity from the surrounding walls, which can be distinguished using LIDAR reflectivity data. Furthermore, reflectivity information of tunnel walls was fused with the road surface reflectivity map to generate a synthetic reflectivity map. When the synthetic reflectivity map was used, localization of vehicles was able through correlation matching with the local maps generated from the current LIDAR data. The experiments were conducted at an expressway including Maseong Tunnel (approximately 1.5 km long). The experiment results showed that the root mean square (RMS) position errors in lateral and longitudinal directions were 0.19 m and 0.35 m, respectively, exhibiting precise localization accuracy.