• 제목/요약/키워드: Life-stress

검색결과 6,100건 처리시간 0.039초

Anti-aging Potential of Extracts Prepared from Fruits and Medicinal Herbs Cultivated in the Gyeongnam Area of Korea

  • Shon, Myung-Soo;Lee, Yunjeong;Song, Ji-Hye;Park, Taehyun;Lee, Jun Kyoung;Kim, Minju;Park, Eunju;Kim, Gyo-Nam
    • Preventive Nutrition and Food Science
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    • 제19권3호
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    • pp.178-186
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    • 2014
  • Many recent studies have focused on maintaining a healthy life by preventing and/or postponing the aging process. Numerous studies have reported that continuous exposure to reactive oxygen species can stimulate skin aging and that excessive accumulation of fat can cause an impaired skin barrier and tissue structure alterations. Thus, the maintenance of antioxidant homeostasis and the suppression of adipose accumulation are important strategies for skin anti-aging. Here, we prepared three types of extracts [whole juice, acetone-perchloric acid (PCA), and ethanol] from 20 fruits and medicinal herbs native to the Gyeongnam area of Korea. The total phenolic content of each extract was analyzed, and we observed higher total phenolic contents in the medicinal herbs. Consistent with this, the results of the oxygen radical absorbance activity capacity assay indicated that the in vitro antioxidant activities of the medicinal herb extracts were stronger than those of the fruit extracts. The fruits and medicinal herbs had strong effects on cell-based systems, including $H_2O_2$-induced oxidative stress in human keratinocytes and 3T3-L1 lipid accumulation. Nishimura Wase persimmon, Taishu persimmon, wrinkled giant hyssop, sweet wormwood, Chinese cedar, red perilla, tan shen, hiyodori-jogo, and cramp bark may be natural anti-aging materials with effective antioxidant and anti-adipogenic activities. Taken together, our findings may provide scientific evidence supporting the development of functional foods and nutraceuticals from fruits and medicinal herbs.

여성이 경험하는 월경전 불편감 (Pre-Menstruation Discomforts Experienced by Women)

  • 김은하;김신정
    • 여성건강간호학회지
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    • 제7권4호
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    • pp.631-641
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    • 2001
  • This study is to investigate women have pre menstruation discomfort, The period of this research was almost one month (from 25, August 2001 to 25, October 2001). The PAF (Premenstrual assessment form), which was made by Park, Myonng-Wha, used for this study. The confidence rate is Crombach's $\alpha$= .9773. Correcting research papers are analyzed by SPSS 7.5 program and normal feature of the subject is divided by frequency, percentage, mean, standard deviation, t-test and ANOVA. The results of this study are as follows; 1. The average age of the subjects is 26.47 age. 220 subjects(44.6%) have gastroenteric trouble like, enteritis, stomachache, laxity. 278 subjects usually have caffeine drink in routine life. 123 subjects(24.9%) have controlled their diet. The average age of the first plowing is 13.55 ages and distribution is between 10 years and 20 years. The average of the uncomfortable point is 2.84. The way to reduce the uncomfortable feeling on the menstruation is taking relax time. 2. All subjects have experienced pre menstruation discomfort, even the degree uncomfortable feeling is different. Through eighteenth categories on the research papers, average point 2.21 were calculated and many subjects have fatigue ($2.89{\pm}1.0614$) and normal physical uncomfortable ($2.84{\pm}1.0633$) and undercurrent water symptom and unsuitability ($2.45{\pm}0.9857$). 3. According to the result of this study, that shows statistical difference; age (F=2.56. p=.037). marriage (t=2.60, p=.009) the number of children(t=2.83, p=.005), stress level(F=13.03, p=.000) job(F=3.91, p=.020). monthly income(t=2.14. p=.032) uncomfortable degree on the menstruation (F=19.121, p=.000), use of contraceptive appliance or pill(t=-2.20, p=.043), schooling (F=3.30, p=.038). Further research is need to understand pie menstruation discomforts, the variables associated with them. And nursing intervention has to considered in program to reduces of pre-menstruation discomforts.

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Depression and Suicide Ideas of Cancer Patients and Influencing Factors in South Korea

  • Lee, Su Jin;Park, Jong Hyock;Park, Bo Young;Kim, So Young;Lee, Il Hak;Kim, Jong Heun;Koh, Dai Ha;Kim, Chang-Hoon;Park, Jae Hyun;Sohn, Myong Sei
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권7호
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    • pp.2945-2950
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    • 2014
  • Background: This study compared risk factors for depression and suicidal ideas among cancer patients for comparison with the general population, and identified influencing factors. Materials and Methods: We analyzed data from 2,472 cancer patients in the National Cancer Center and nine Regional Cancer Centers and frequency-matched data for age and sex from 2,349 members of the general population who completed the National Health and Nutrition Examination Survey in 2008. Logistic regression analysis was used to identify factors affecting depression and suicidal ideas. Results: Cancer patients were not likely to have more depression (OR=0.96, 95%CI=0.79-1.18) and were less likely to have suicidal ideas (OR=0.64, 95%CI=0.53-0.79) compared to the general population. Female sex, more stress, and lower quality of life were influencing factors. The additional risk factors for suicidal ideas among cancer patients included income (OR=0.62, 95%CI=0.43-0.91), smoking (OR=1.63, 95% CI=1.06-2.50), recurrence (OR=1.50, 95%CI=1.15-1.95), and chemotherapy (OR=1.66, 95%CI=1.26-2.19). Conclusions: No differences appeared in depression rates between cancer patients and the general population, and cancer patients were less likely to have suicidal ideas. However, cancer patients were likely to have more risk factors than the general population, and those classified as being at high risk of suicide should receive distress management and social economic support, from early in the treatment process.

Q-switched 레이저와 다중센서/단일채널 신호수집을 이용한 복합재 구조 음향방출 트레이닝 및 위치탐지 기법 개발 (Development of Acoustic Emission Training Technique and Localization Method using Q-switched Laser and Multiple Sensors/Single Channel Acquisition)

  • 최윤실;이정률
    • Composites Research
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    • 제31권4호
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    • pp.145-150
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    • 2018
  • 항공우주산업에서 구조물의 수명연장과 경제적 측면에서의 효율적인 운용을 위해 다양한 구조건전성모니터링(Structural Health Monitoring, SHM) 기법들이 제시되어왔다. 금속재 구조물의 경우, 수분이나 염분 등에 의한 부식이나 쉽게 응력집중이 발생하는 타공, 노치, 볼트 등과 같은 위치에서의 균열이 주된 관심사였으나, 항공우주산업에서의 복합재 사용비율이 증가함에 따라 손상 메커니즘이 더욱 복잡한 복합재 구조물에 적용이 가능한 고도화된 SHM 시스템의 필요성이 강조되고 있다. 본 논문에서는 Q-switched 레이저와 다수의 압전센서를 이용한 복합재에서의 AE(Acoustic emission) 위치탐지 기법을 제시한다. 제시되는 기법은 10 mm 이내의 거리오차로 방출위치 탐지를 목표로 하며 복합재 구조에서 수행된 AE 모사실험 및 위치탐지 시도 결과를 제시하여 기법이 유효함을 증명한다.

여대생의 BMI에 따른 식이섭취와 혈중지질 농도 및 항산화능 (Body Mass Index, Dietary Intake, Serum Lipids and Antioxidant Status of Young Females)

  • 배현숙
    • 대한지역사회영양학회지
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    • 제11권4호
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    • pp.479-487
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    • 2006
  • Many epidemiological and observational studies show that distorted body image of normal body weight is widespread among Korean young females. This study was performed to evaluate the prevalence of overweight and underweight of young females and, to compare nutrient intakes, body composition, serum indices (lipids, MDA: Malondialdehyde, TAS : Total Antioxidant Status) with different BMI groups. The subjects were 75 university students in Seoul. We divided the subjects into 3 groups according to their BMI by IOTF guideline (UW: underweight group, BMI < 18.5, NW: normal body weight group; 18.5 $\leq$ BMI < 23.0, OW: overweight group; BMI $\geq$ 23.0). Data on dietary intakes, body compositions and serum indices were obtained in 3 groups. Differences on all of the above variables were assessed by body weight groups. Using IOTF guidelines, the prevalence of overweight and underweight in young females were 23%, 61%, 16% respectively. $\beta$-carotene and vitamin A intake of UW were significantly higher than that of NW (p < 0.05). Fiber intakes of NW was significantly higher than that of W (p < 0.05). But intakes of energy and the other nutrients were not significantly different among BMI groups. Calcium and folate intakes were 75%, 61% of KDRIs. Serum TGs were significantly higher in OW than that of NW, UW (p < 0.05), but level of MDA and TAS were not significantly different. The association of overweight and low intake of $\beta$-carotene and vitamin A may be one of many factors predisposing obese females to a high risk of oxidative stress later in life. This requires urgent nutritional intervention programs involving enough intake of fruit and vegetables, with modification of inappropriate dietary habits.

미소시험편을 이용한 고온 크리프 특성 평가법 개발 (Development of High Temperature Creep Properties Evaluation Method using Miniature Specimen)

  • 유효선;백승세;이송인;하정수
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2000년도 춘계학술대회논문집A
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    • pp.43-48
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    • 2000
  • In this study, a small punch creep(SP-Creep) test using miniaturized specimen$(10{\times}10{\times}0.5mm)$ has been described for the development of the newly semi-destructive creep test method for high temperature structural components such as headers and tubes of boiler turbine casino and rotor and reactor vessel. The SP-Creep testing technique has been applied to 2.25Cr-1Mo(STBA24) steel used widely as boiler tube material and the creep test temperature are varied at $550^{\circ}C{\sim}600^{\circ}C$. The overall deformations of SP-Creep curves are definitely depended with applied load and creep test temperature and show the creep behaviors of three steps like conventional uniaxial creep curves. The steady state creep rate${\delta}_{ss}$ of SP-Creep curve for miniaturized specimen increases with increasing creep temperature, but the exponential value with creep loading is decreased. The activation energy$(Q_{spc})$ during SP-Creep deformation with various test temperatures shows 605.7kJ/mol that is g.eater than 467.4kJ/mol reported in uniaxial creep test. This may be caused by the difference of stress states during creep deformation In two creep test. But from the experimental results, e.g. SP-Creep curve behaviors, the steady state creep rate${\delta}_{ss}$ with creep temperature, and the exponential value(n) with creep loading, it can be summarized that the SP-Creep test may be a useful test method to evaluate the creep properties of the heat resisting material.

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컴퓨터 시뮬레이션을 이용한 자동차용 Torque Strut의 경량 설계 (Light-Weight Design of Automotive Torque Strut Based on Computer Aided Engineering)

  • 김기주
    • 대한기계학회논문집A
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    • 제41권10호
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    • pp.975-981
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    • 2017
  • 알루미늄 합금과 같은 경량소재의 적용을 통한 무게 감소는 연료절감과 대기 오염 감소에 기여할 수 있다. 알루미늄 합금 재료는 피로수명에 대한 강도 측면에서 철강(steel) 소재에 비하여 취약한 단점을 가지고 있다. 부품들의 안전성을 희생시키지 않고 자동차 부품 경량화를 이루기 위해 많은 연구자들이 보다 가볍고 강한 서스펜션 링크들에 관한 연구를 진행해 왔다. 본 연구에서는 기존 STKM11A 철강소재로 설계된 토크 스트럿을 245 MPa의 인장강도 소재인 알루미늄 합금(A356) 소재로 대체하기 위한 경량화 설계 과정에 대하여 von-Mises 응력 변화를 분석하여 연구하였다. 최적화된 설계는 경량화 이전 강재로 설계된 링크보다 42% 이상 경량화 시킬 수 있었으며 이는 토크 스트럿 개발의 안전한 경량화 설계조건 및 경량화 설계에 대한 가이드에 참고가 될 수 있을 것이다.

지하탄약고의 설계요소 및 폭발안전 연구 (Design consideration and explosion safety of underground ammunition storage facilities)

  • 김운영;이명재;김민석;김준엽;주효준
    • 한국터널지하공간학회 논문집
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    • 제5권1호
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    • pp.55-70
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    • 2003
  • 지상형 탄약저장시설은 폭발시 인명과 재산의 피해가 크고 외부공격에 대하여 취약하므로 안전성, 부지확보 및 유지관리에서 유리한 지하탄약고의 개발이 절실하다. 본 연구에서는 폭발시 안전성 및 수불장비의 동선을 고려한 지하탄약고 시설배치와 방폭시설의 국내 설계사례를 소개하였다. ${\bigcirc}{\bigcirc}$지하탄약고는 경암지역에 불연속면의 영향이 적도록 주응력방향과 거의 평행하게 3개소의 저장격실이 배치되도록 설계되었다. 또한 국방부 폭발안전기준을 만족하는 안전거리를 확보하였고, 탄약 수불장비의 동선 시뮬레이션을 통해 시설배치의 적절성을 검증하였다. 방폭시설은 임의 저장격실의 우발적 폭발시 발생하는 최대 폭풍압을 산정하여 연쇄폭발이 발생하지 않도록 인접격실의 보호를 위한 방폭문 및 방폭밸브 등을 설계하였고. 폭풍압의 저감을 위한 병목장치, 파편함정 등의 시설은 구조해석을 통해 국방부 폭발물안전기준을 만족하도록 규격을 결정하였다.

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부모역할행동에 미치는 복합적 영향들에 관한 고찰 (A Study on Multiple Influences on Parenting)

  • 전경숙
    • 한국생활과학회지
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    • 제5권2호
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    • pp.1-16
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    • 1996
  • This study has examined multiple influences of several variables on parenting behavior by looking into illustrative studies. This study provides support to the view that various factors influence parenting and that parenting behavior is multiply determined. Characteristics of parents, children and the context in which parent-child relations occur cause different childrearing patterns among parents. This study can be summarized as follows: 1) Parental behavior is influenced to a large degree by what the parent brings to the situation. In other words, characteristics of the parent including personality characteristics, interpersonal skills, problem-solving skills, level of maturity, values and childrearing beliefs contribute to individual differences in parenting. 2) The parent's relationship history influences the personality characteristics that the parent brings to his or her adult roles. To understand who the parent is today, we have to look at who the parent was, and what the parent was doing in the years prior to parenthood. That is, we need to see the life course of the individual before parenthood. 3) Contextual variables including the immediate context and the larger context have proved to influence parental behaviors. Characteristics of the immediate context such as the quality of marital rationship can influence the parent's psychological well-being and his or her behavior toward the childen while characteristics of the larger context such as the economic situation and the neighborhood can influence the level of stress experienced by the parent and cosequently how the parent relates to his or her child. 4) In order to understand the development of the parent-child relationship we need to look at the characteristics of the child. Children may elicit positive behaviors from their parents, or they may possess characteristics that the parents find aversive thus leading to difficulties in the relationship. Therefore, much depends on the fit beween the characteristics of the parents and characteristics of the child. By examining multiple contemporaneous influences on parenting, this study could deepen the understanding of why parents have different childrearing patterns, why some parents fail to meet their children's demands and why parents act in certain ways. What we ultimately hope is that as we learn more about parenting and the development of parent-child relationships, we will be better able to provide parents with the supports they need to achieve their parenting goals.

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Comparisons of Chicken Muscles between Layer and Broiler Breeds Using Proteomics

  • Jung, K. C.;Jung, W. Y.;Lee, Y. J.;Yu, S. L.;Choi, K. D.;Jang, B. G.;Jeon, J. T.;Lee, J. H.
    • Asian-Australasian Journal of Animal Sciences
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    • 제20권3호
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    • pp.307-312
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    • 2007
  • The present study was carried out to investigate differentially expressed chicken muscle proteins using proteomics approach. More than 300 protein spots were investigated for the muscle samples in 2DE gels and the differentially expressed protein spots between pectoralis and peroneus longus muscles from Cornish and White Leghorn breeds were characterized by MALDI-TOF. In pectoralis muscles, PGAM1 protein was detected as differentially expressed between White Leghorn and Cornish breeds. On the other hand, 4 protein spots (SP22, nxf-2, SOD1, TNNI2) were differentially expressed between White Leghorn and Cornish breeds in peroneus longus muscles. These proteins assumed to be related with muscle development, growth, stress, and movements in chicken. In this experimental process, 2D reference map of the chicken muscle proteins was needed and 25 proteins, which were commonly expressed in both pectoralis and peroneus longus muscles in both breeds, were selected and characterized. Upon finishing the exact roles of the differentially expressed proteins, the identified 5 proteins will be used as valuable information for the fundamental mechanisms of muscle biology and underline genetics.