• Title/Summary/Keyword: Life-stress

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Design of Portable Welded-Nitrogen Vessel (11 kg, 10 L and 50 bar) for Shipbuilding (선박용 휴대형 질소용기(11 kg, 10 L 및 50 bar)의 두께 및 외형 설계)

  • Seong, Hansaem;Kim, Jaeyeol;Eom, Taejin;Kawk, Hyo Seo;Lee, Kwang O;Kim, Chul
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.41 no.4
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    • pp.263-270
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    • 2017
  • The shipbuilding industry uses large stationary tanks to store low-pressure air, which is used to open and close large shut-off valves. However, when supplying air from the tank to a distant valve, there are problems related to the need for supplementary pipes and the pressure drop during transportation. In this study, a portable welded vessel for storing high-pressure nitrogen (11 kg, 10 L, and 50 bar) was designed to prevent air leakage and improve the convenience of workers. This pressure vessel was elliptical to reduce the number of welded parts, which are structurally weak. The thickness and ratio of the major and minor axes of the pressure vessel were calculated to verify its structure stability at the working pressure (50 bar), and that the proposed weight and capacity were satisfactory. The residual stress caused by the welding process was calculated by performing a transient thermal-structural coupled field analysis using the ANSYS parametric design language (APDL), and the fatigue life of the vessel was verified based on the Goodman criterion.

Effects of Financial College Tuition Support by Korean Parents using a Hierarchical Bayes Model (계층적 베이즈 모형을 이용한 대학등록금에 대한 부모님의 경제적 지원 영향 분석)

  • Oh, Man-Suk;Oh, Hyun Sook;Oh, Min Jung
    • The Korean Journal of Applied Statistics
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    • v.26 no.2
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    • pp.267-280
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    • 2013
  • College tuition is a significant economic, social, and political issue in Korea. We conduct a Bayesian analysis of a hierarchical model to address the factors related to college tuition based on a survey data collected by Statistics Korea. A binary response variable is selected depending on if more than 70% of tuition costs are supported by parents, and a hierarchical Probit model is constructed with areas as groups. A set of explanatory variables is selected from a factor analysis of available variables in the survey. A Markov chain Monte Carlo algorithm is used to estimate parameters. From the analysis results, income and stress are significantly related to college tuition support from parents. Parents with high income tend to support children's college tuition and students with parents' financial support tend to be mentally less stressed; subsequently, this shows that the economic status of parents significantly affects the mental health of college students. Gender, a healthy life style, and college satisfaction are not significant factors. Comparing areas in terms of the degrees of correlation between stress/income and tuition support from parents, students in Kangwon-do are the most mentally stressed when parents' support is limited; in addition, the positive correlation between parents support and income is stronger in big cities compared to provincial areas.

Effects of Hypoxia on the Fertilization and Early Development of Sea Urchin, Strongylocentrotus nudus (둥근성게 (Strongylocentrotus nudus)의 수정과 초기 배발생에 미치는 빈산소의 영향)

  • Lee, Gun-Sup;Hwang, Jin-Ik;Chung, Young-Jae;Kim, Dong-Giun;Moh, Sang-Hyun;Chang, Man;Lee, Taek-Kyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.8
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    • pp.3785-3791
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    • 2012
  • Dissolved oxygen is one of the most important factors controlling growth in aquatic organisms. Hypoxia is generally defined as dissolved oxygen less than 2.8 mg $O_2/L$ (equivalent to 2 mL $O_2/L$ or 91.4 mM). Therefore, hypoxia zone can cause a serious problem in marine ecosystem. In this study, to investigate embryotoxic (fertilization and embryo development rates) effects of hypoxia on sea urchin Strongylocentrotus nudus were exposed to dissolved oxygen levels of 7.6 mg $O_2/L$ (normoxia) and 1.8 mg $O_2/L$ (hypoxia) for 2 days at $15^{\circ}C$ and 33 ‰. Also, Expression levels of stress related gene (HSP70) and antioxidant related gene (glutathione reductase) in the sea urchins exposed to hypoxia were confirmed by Immunoblotting and RT-PCR analysis. In results, we showed that developmental rates were dramatically reduced in hypoxia condition. Molecular analysis demonstrated that higher HSP70 (5.5 fold) and glutathione reductase gene (2.79 fold) were present in the sea urchin exposed to hypoxia. Our results suggested that hypoxia can cause the abnormal development and elicits a stress and antioxidant response on sea urchin.

Studies on the tolerance of Halophyte Arabis stelleri under heavy metals and Salt stress condition (염생식물 섬갯장대(Arabis stelleri var. japonica)의 중금속 및 고염 농도 스트레스 상태에서 내성 연구)

  • Kim, Donggiun
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.4
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    • pp.373-378
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    • 2019
  • In the marine area, the salt concentration in the soil increases, and the inland heavy metal pollution increases the damage of plants. In the inland industrial development area, researches on the genetic resources of plants together with the heavy metal accumulation of Co, Ni, Zn, and so on are required. Both of these problems have caused scientists to work hard to find plants that are likely to cause stress in plant roots. In this study, seeds of Arabis stelleri var. japonica collected near the shore were used for germination. The growth and development and tolerance of both Arabis and Arabidopsis seeds were investigated under laboratory culture conditions. As a result, Arabis showed resistance about 3 times in 250 mM nickle and cobalt, and more than 4 times in 1 mM zinc when compared to Arabidopsis. The tolerance of Arabis to Na salts increased by 20% or more at 50 mM concentration and Arabis was resistant to heavy metals and salt concentration. The accumulation of Na ions in the body was measured as a preparation for studying the intracellular mechanism. As a result, it showed a further decrease in resistance to ground water roots. It is considered that the activity of the exporting gene is important rather than the mechanism of accumulation.

Schisandrae Fructus ethanol extract attenuates particulate matter 2.5-induced inflammatory and oxidative responses by blocking the activation of the ROS-dependent NF-κB signaling pathway

  • Lee, Hyesook;Park, Cheol;Kwon, Da Hye;Hwangbo, Hyun;Kim, So Young;Kim, Min Yeong;Ji, Seon Yeong;Kim, Da Hye;Jeong, Jin-Woo;Kim, Gi-Young;Hwang, Hye-Jin;Choi, Yung Hyun
    • Nutrition Research and Practice
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    • v.15 no.6
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    • pp.686-702
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    • 2021
  • BACKGROUND/OBJECTIVES: Schisandrae Fructus, the fruit of Schisandra chinensis Baill., has traditionally been used as a medicinal herb for the treatment of various diseases, and has proven its various pharmacological effects, including anti-inflammatory and antioxidant activities. In this study, we investigated the inhibitory effect of Schisandrae Fructus ethanol extract (SF) on inflammatory and oxidative stress in particulate matter 2.5 (PM2.5)-treated RAW 264.7 macrophages. MATERIALS/METHODS: To investigate the anti-inflammatory and antioxidant effects of SF in PM2.5-stimulated RAW 264.7 cells, the levels of pro-inflammatory mediator such as nitric oxide (NO) and prostaglandin E2 (PGE2), cytokines including interleukin (IL)-6 and IL-1β, and reactive oxygen species (ROS) were measured. To elucidate the mechanism underlying the effect of SF, the expression of genes involved in the generation of inflammatory factors was also investigated. We further evaluated the anti-inflammatory and antioxidant efficacy of SF against PM2.5 in the zebrafish model. RESULTS: The results indicated that SF treatment significantly inhibited the PM2.5-induced release of NO and PGE2, which was associated with decreased inducible NO synthase and cyclooxygenase-2 expression. SF also attenuated the PM2.5-induced expression of IL-6 and IL-1β, reducing their extracellular secretion. Moreover, SF suppressed the PM2.5-mediated translocation of nuclear factor-kappa B (NF-κB) from the cytosol into nuclei and the degradation of inhibitor IκB-α, indicating that SF exhibited anti-inflammatory effects by inhibiting the NF-κB signaling pathway. In addition, SF abolished PM2.5-induced generation of ROS, similar to the pretreatment of a ROS scavenger, but not by an inhibitor of NF-κB activity. Furthermore, SF showed strong protective effects against NO and ROS production in PM2.5-treated zebrafish larvae. CONCLUSIONS: Our findings suggest that SF exerts anti-inflammatory and antioxidant effects against PM2.5 through ROS-dependent down-regulating the NF-κB signaling pathway, and that SF can be a potential functional substance to prevent PM2.5-mediated inflammatory and oxidative damage.

A Study on Behavior Characteristics of Reinforcement Zone of Block Type Mechanically Stabilized E arth Wall by Field Measurement in Curved Section (현장 계측을 통한 블록형 보강토옹벽 곡선부 보강 영역의 거동 특성 연구)

  • Lee, So-Yeon;Kim, Young-Je;Oh, Dong-Wook;Lee, Yong-Joo;Jung, Hyuk-Sang
    • Journal of the Korean Geosynthetics Society
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    • v.18 no.2
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    • pp.23-36
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    • 2019
  • In this paper, field measurement of the Block Type Mechanically Stabilized Earth (MSE) wall curved section was performed, and the reinforced area of the curved part is studied through the result. MSE method has been applied to various fields because of easy construction and excellent economic efficiency, so that it can be easily access in our life. However due to lack of compaction and stress concentration phenomenon, cracks and collapse occur in the curve of MSE wall, which is important for safety. The cause of collapse is lack of research on curved section, lack of design criteria, lack of construction due to economical efficiency and shortening of construction period, insufficient compaction space. In this study, therefore, it was examined the existing design and construction standards, analyzed the cause through accident examples of the curved section of the Block Type MSE wall. As a result, the horizontal displacement of the curved section was 90% higher than that of the straight section and 60% higher than that of the concave section. In the case of the convex section in the curved section reinforcement region, the maximum displacement is shown in the H/2 section in the horizontal direction from the center of the MSE wall, and the range of influence from H is shown. In the case of the concave section, the maximum displacement is shown in the center, The minimum displacement was confirmed in H/4 section in the horizontal direction from the center of the MSE wall. As a basic study on the reinforcement area rehabilitation through the actual construction of block type MSE wall, the behaviors of the straight part and the curved part were compared and analyzed. And analyzed the reinforced area in order to reduce the damage of the stress concentration phenomenon and secure the safety.

The effect of seasonal thermal stress on milk production and milk compositions of Korean Holstein and Jersey cows

  • Lim, Dong-Hyun;Mayakrishnan, Vijayakumar;Ki, Kwang-Seok;Kim, Younghoon;Kim, Tae-Il
    • Animal Bioscience
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    • v.34 no.4
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    • pp.567-574
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    • 2021
  • Objective: In this study we investigated the effect of seasonal thermal stress on milk production and milk compositions between Holstein and Jersey dairy cows under the temperate-climate in Korea. Methods: A total of 9 Holstein lactating dairy cows (2.0±0.11 parity) which had a daily milk yield of 29.77±0.45 kg, and days in milk of 111.2±10.29 were selected similarly at the beginning of the experiments in each season. Also, a total of 9 Jersey lactating dairy cows (1.7±0.12 parity) which had a daily milk yield of 20.01±0.43 kg, and days in milk of 114.0±9.74 were selected similarly at the beginning of the experiments. Results: Results showed that the average ambient temperature (℃) and temperature-humidity index (THI) were higher in summer, and were lower in winter (p<0.05). The average relative humidity (RH, %) was higher in autumn than that of other seasons (p<0.05). Milk production was significantly decreased (Holstein 29.02 kg/d and Jersey 19.75 kg/d) in autumn than in other seasons (Holstein 30.14 kg/d and Jersey 20.96 kg/d). However, the milk production was negatively correlated in Holstein cows, and positively correlated in Jersey cows with THI values increased from 16 to 80. In addition, milk yield was increased by 15% in Holstein cows and decreased by 11% in Jersey cows with the THI values increased from 16 to 20. The fat and protein content percentage was significantly higher in Jersey milk than in Holstein milk, furthermore the fat and protein content yield was higher in Jersey cow milk than that of Holstein cow's milk with all THIs. Conclusion: From the study results, we concluded that Jersey cows might be less adaptable to low temperature of the winter, and this would have a negative impact on dairy farmer income since Korea's milk price estimation system places a higher value on milk yield than on milk compositions or sanitary grades.

Thickness Design of Composite Pavement for Heavy-Duty Roads Considering Cumulative Fatigue Damage in Roller-Compacted Concrete Base (롤러전압콘크리트 기층의 누적피로손상을 고려한 중하중 도로의 복합포장 두께 설계)

  • Kim, Kyoung Su;Kim, Young Kyu;Chhay, Lyhour;Lee, Seung Woo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.42 no.4
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    • pp.537-548
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    • 2022
  • It is important to design the pavement thickness considering heavy-duty traffic loads, which can cause excessive stress and strain in the pavement. Port-rear roads and industrial roads have many problems due to early stress in pavement because these have a higher ratio of heavy loads than general roads such as national roads and expressways. Internationally, composite pavement has been widely applied in pavement designs in heavy-duty areas. Composite pavement is established as an economic pavement type that can increase the design life by nearly double compared to that of existing pavement while also decreasing maintenance and user costs. This study suggests a thickness design method for composite pavement using roller-compacted concrete as a base material to ensure long-term serviceability in heavy-duty areas such as port-rear roads and industrial roads. A three-dimensional finite element analysis was conducted to investigate the mechanical behavior and the long-term pavement performance ultimately to suggest a thickness design method that considers changes in the material properties of the roller-compacted concrete (RCC) base layer. In addition, this study presents a user-friendly catalog design method for RCC-base composite pavement considering the concept of linear damage accumulation for each container trailer depending on the season.

Damage-Spread Analysis of Heterogeneous Damage with Crack Degradation Model of Deck in RC Slab Bridges (RC 슬래브교의 바닥판 균열 열화모델에 따른 이종손상 확산 분석)

  • Jung, Hyun-Jin;An, Hyo-Joon;Kim, Jae-Hwan;Part, Ki-Tae;Lee, Jong-Han
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.26 no.6
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    • pp.93-101
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    • 2022
  • RC Slab bridges in Korea account for more than 70% of the total bridges for more than 20 years of service. As the number of aging structures increases, the importance of safety diagnosis and maintenance of structures increases. For highway bridges, cracks are a main cause of deck deterioration, which is very closely related to the decrease in bridge durability and service life. In addition, the damage rate of expansion joints and bearings accounts for approximately 73% higher than that of major members. Therefore, this study defined damage scenarios combined with devices damages and deck deterioration. The stress distribution and maximum stress on the deck were then evaluated using design vehicle load and daily temperature gradient for single and combined damage scenarios. Furthermore, this study performed damage-spread analysis and predicted condition ratings according to a deck deterioration model generated from the inspection and diagnosis history data of cracks. The heterogeneous damages combined with the member damages of expansion joints and bearings increased the rate of crack area and damage spread, which accelerated the time to reach the condition rating of C. Therefore, damage to bridge members requires proper and prompt repair and replacement, and otherwise it can cause the damage to bridge deck and the spread of the damage.

Influence of dietary organic trace minerals on enteric methane emissions and rumen microbiota of heat-stressed dairy steers

  • A-Rang Son;Mahfuzul Islam;Seon-Ho Kim;Sung-Sill Lee;Sang-Suk Lee
    • Journal of Animal Science and Technology
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    • v.65 no.1
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    • pp.132-148
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    • 2023
  • Ruminants are the main contributors to methane (CH4), a greenhouse gas emitted by livestock, which leads to global warming. In addition, animals experience heat stress (HS) when exposed to high ambient temperatures. Organic trace minerals are commonly used to prevent the adverse effects of HS in ruminants; however, little is known about the role of these minerals in reducing enteric methane emissions. Hence, this study aimed to investigate the influence of dietary organic trace minerals on rumen fermentation characteristics, enteric methane emissions, and the composition of rumen bacteria and methanogens in heat-stressed dairy steers. Holstein (n=3) and Jersey (n=3) steers were kept separately within a 3×3 Latin square design, and the animals were exposed to HS conditions (Temperature-Humidity Index [THI], 82.79 ± 1.10). For each experiment, the treatments included a Control (Con) consisting of only basal total mixed rations (TMR), National Research Council (NRC) recommended mineral supplementation group (NM; TMR + [Se 0.1 ppm + Zn 30 ppm + Cu 10 ppm]/kg dry matter), and higher concentration of mineral supplementation group (HM; basal TMR + [Se 3.5 ppm + Zn 350 ppm + Cu 28 ppm]/kg dry matter). Higher concentrations of trace mineral supplementation had no influence on methane emissions and rumen bacterial and methanogen communities regardless of breed (p > 0.05). Holstein steers had higher ruminal pH and lower total volatile fatty acid (VFA) concentrations than Jersey steers (p < 0.05). Methane production (g/d) and yield (g/kg dry matter intake) were higher in Jersey steers than in Holstein steers (p < 0.05). The relative abundances of Methanosarcina and Methanobrevibacter olleyae were significantly higher in Holstein steers than in Jersey steers (p < 0.05). Overall, dietary organic trace minerals have no influence on enteric methane emissions in heat-stressed dairy steers; however, breed can influence it through selective alteration of the rumen methanogen community.