• Journal of Acupuncture Research
• /
• v.31 no.4
• /
• pp.81-97
• /
• 2014

Objectives : The purpose of this study is analyzing the current research methodology of pharmacopucture for the treatment of animal cancer models. Methods : Four electronic databases were searched for animal studies published from January 2000 to September 2014 onward using these search terms "cancer, anticancer, pharmacopuncture, beevenom". Selected articles were described about animal cancer models. The methods used to induce cancer and the outcome measures used to assess the effects of pharmacopuncture on animal cancer models were analyzed. Results : 37 articles were included. For producing animal cancer models BALB/C mice(n=22) and C57BL/6 mice(n=17) were selected. And intravenous injection of B16-F10 melanoma cells into tail vein(n=14) or intraperitoneal injection of sarcoma-180 cells(n=14) were frequently used to induce cancer. Various pharmacopunctures were injected into acupoints $CV_{12}(n=19)$, $ST_{36}(n=8)$, $BL_{18}(n=8)$ or peritoneal cavity(n=6), tumor site(n=2), tail vein(n=2). Outcome measures were categorized into anti-cancer, anti-metastasis, general condition, cytotoxicity, immune response, toxicity. Median Survival Time(MST) and increase of life span(ILS)(n=26) was frequently used for evaluating anti-cancer effects. And pulmonary colonization assay(n=13) was frequently used for evaluating anti-metastasis effects Conclusions : Based on these data, further research would be needed to ascertain the effectiveness of pharmacopuncture for treating cancer and broaden the range of clinical applications.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.7
• /
• pp.4121-4126
• /
• 2013

Objective: Low dose radiation may stimulate the growth and development of animals, increase life span, enhance fertility, and downgrade the incidence of tumor occurrence.The aim of this study was to investigate the antitumor effect and hormesis in an erythrocyte system induced by low-dose radiation. Methods: Kunming strain male mice were subcutaneously implanted with S180 sarcoma cells in the right inguen as an experimental in situ animal model. Six hours before implantation, the mice were given 75mGy whole body X-ray radiation. Tumor growth was observed 5 days later, and the tumor volume was calculated every other day. Fifteen days later, all mice were killed to measure the tumor weight, and to observe necrotic areas and tumor-infiltration-lymphoreticular cells (TILs). At the same time, erythrocyte immune function and the level of 2,3-diphosphoglyceric acid (2,3-DPG) were determined. Immunohistochemical staining was used to detect the expression of EPO and VEGFR of tumor tissues. Results: The mice pre-exposed to low dose radiation had a lower tumor formation rate than those without low dose radiation (P < 0.05). The tumor growth slowed down significantly in mice pre-exposed to low dose radiation; the average tumor weight in mice pre-exposed to low dose radiation was lighter too (P < 0.05). The tumor necrosis areas were larger and TILs were more in the radiation group than those of the group without radiation. The erythrocyte immune function, the level of 2,3-DPG in the low dose radiation group were higher than those of the group without radiation (P < 0.05). After irradiation the expression of EPO of tumor tissues in LDR group decreased with time. LDR-24h, LDR-48h and LDR-72h groups were all statistically significantly different from sham-irradiation group. The expression of VEGFR also decreased, and LDR-24h group was the lowest (P < 0.05). Conclusion: Low dose radiation could markedly increase the anti-tumor ability of the organism and improve the erythrocyte immune function and the ability of carrying $O_2$. Low-dose total body irradiation, within a certain period of time, can decrease the expression of hypoxia factor EPO and VEGFR, which may improve the situation of tumor hypoxia and radiosensitivity of tumor itself.

• Journal of Korean society of Dental Hygiene
• /
• v.9 no.4
• /
• pp.644-658
• /
• 2009

Objectives : This study was to find out the status of job satisfaction and intent to leave the job for dental hygienists, and those factors affecting their intent to leave, so as to prevent dental hygienists from leaving their jobs in advance, and to strive for extending the life span of the job, contributing to improve dental care services provided by dental hygienists. Methods : The data were collected from 280 dental hygienists working in dental clinics or hospitals in Busan and Gyeongnam area by using a structured and self-administered questionnaire through mail, from February 1 to March 15, 2009, and were analyzed by using SPSS WIN 14.0 program. Results : First, It was the most prevalent for the dental hygienists surveyed to be between 100 to 149 thousand won in the level of monthly as 42.3%, and to be the assistance of dental examination and treatment for main duty as 62.5%. Leaving job was experience by 51.6% of the subjects, with work condition as the most common reason for 32.2%. Second, the degree of job satisfaction was 3.4 points overall in the score of 5 point Likert's scale on the average, showing affirmative level above the average, and significantly different according to certain characteristics such as age, education level, total years of work career, years of work career in the current job, monthly salary level, whether to provide monthly paid leave, and the number of patients treated per day. It also was significantly correlated with some structural factors and variables consisting attitude and value, including equity in pay(r=0.612), job perception as dental hygienist(r=0.573), work environment(r=0.552), self growth(r=0.531), affirmative attitude(r=0.421), and so on. Third, the mean score of intent to leave was 2.73 overall and lower than the average, showing significant relationship with some characteristics, such as age, marital status, education level, total years of work career, years of work career in the current job, monthly salary level, whether to provide monthly paid leave, and the number of patients treated per day. Intent to leave also showed the highest correlation with job satisfaction(r=-0.708), followed by equity in pay(r=-0.482), self growth (r=-0.453), job perception as dental hygienist(r=-0.392), work environment(r=-0.362), etc. Forth, job satisfaction was significantly influenced by some factors including equity in pay, followed by job perception as dental hygienist, relationship with fellow colleagues, affirmative attitude and work environment, and so on. Fifth, the intent to leave was significantly affected not only by job satisfaction but also by some structural factors including equity in pay, self growth and job perception as dental hygienist. Conclusions : The above results showed that the equity in pay was the most important factor for the intent to leave the job as well as job satisfaction among dental hygienists, thus suggesting that systematic measures should be provided to improve the job satisfaction to prevent economic loss due to leaving job frequently, and to provide pertinent reward system as a profession to enhance the motivation for accomplishment on job for dental hygienists.

• Archives of Plastic Surgery
• /
• v.35 no.6
• /
• pp.698-702
• /
• 2008

Purpose: Basal cell carcinoma is one of the most common cancers in the western population and the annual incidence rate is still on an increasing course. In Asian countries such as Korea, the incidence of basal cell carcinoma is reported to be remarkably low but is estimated to be in a steep increase nowadays. This study was to analyze the recent clinical trends of basal cell carcinoma in Korea by reviewing a single institution's experience. Methods: Throughout an 11-year period, the surgical excision of 143 cases of basal cell carcinoma was performed in our department. General data of these cases such as the primary site of cancer, age and sex of the patient, operative methods, recurrence rate were reviewed retrospectively. Results: Among the 143 patients included in this study, 82 patients were men and 61 patients were women. The ages ranged from 27 to 89 years with a mean age of 64.0 years. The head and neck region was the most frequently involved primary site for the cancer as 95.1% of the total cases occurred in this area. Especially the nose and perinasal area were the most frequent region, which was followed by the periorbital area, cheek, and perioral area. During this study period, 9 cases showed recurrence of the cancer as the overall recurrence rate was 6.3%. Conclusion: Gradual increase in the incidence of basal cell carcinoma was demonstrated in this study. Basal cell carcinoma showed high incidence in the old-age population as 68.5% of the total patients were more than 60 years of age. High recurrence rate was noted in the nasal region especially after local flap reconstruction. A more cautious approach is to be required when handing such high risk lesions. Multiple factors such as extended life span, increased outdoor leisure activity and exposure to sunlight, higher accessibility to medical services and increased understanding of the public about skin cancer are assumed to be the main reasons for this increase of basal cell carcinoma.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.40 no.1
• /
• pp.9-16
• /
• 2004

Parapenaeopsis tenella occurs widely on the south and west coasts of Korea. Sex ratio showed seasonal variations, with a mean value of 48.6% for the females. The species produces one cohort a year, with the ovaries ripening from July to August. Insemination took place from July to August, as more than half of the females sampled in the study over 14 mm CL were inseminated. Gonadosomatic index (GSI) reached the maximum between July and August. The smallest mature female was 11 mm CL. Size at 50% sexual maturity ($CL_{50}$), determined from both mature females and inseminated females, was 12.53 mm and 12.28 mm CL, respectively. The life span of females appeared to be 14-15 months according to size frequency distributions, while that of the male was 13-14 months. Population growth was estimated by the modified von Bertalanffy growth function incorporating seasonal variation in growth. Based on the growth parameters (K = 1.22 $yr^{-1}$ and $L_{\infty}$ = 21.99 mm CL for females, and K = 2.00 $yr^{-1}$ and $L_{\infty}$ = 15.00 mm CL for males) growth curves showed that females grew faster and reached a larger size at age than males.

• Journal of Gastric Cancer
• /
• v.7 no.2
• /
• pp.67-73
• /
• 2007

Purpose: There have been several comparative studies that have focused on elderly groups of patients with gastric cancer. However, new criteria are needed for this elderly group because of the longer life span of Korean people. The diagnosis of gastric cancer has sometimes been missed in the young age group. The perioperative risk is high in the elderly age group because of their combined diseases. This study was designed to determine the differences of the clinicopathologic features and the prognosis between young and elderly patients with gastric cancer. Materials and Methods: Eighty patients were divided in two groups and these patients were selected for making comparison between young and elderly groups of patients with gastric cancer. The young age group consisted of 31 patients who were aged 35 years old or less. The elderly age group was made up of 49 patients who were aged 75 years old or above. Results: For the clinicopathologic features, the young age group was characterized by a high incidence of the poorly differentiated type of adenocarcinoma and the diffuse type too, according to the Lauren classification. On the other hand, the elderly group was characterized by a high incidence of poorly to moderate differentiated adenocarcinoma and also the intestinal type according to the Lauren classification. The other clinical differences were unremarkable. Additionally, there was no survival advantage in the young age group compared to the elderly group. Conclusion: There were no clinicopathologic and prognostic differences between both extreme age groups. So, active surgical treatment is recommended even for the elderly patients group.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.35 no.2
• /
• pp.481-491
• /
• 2015

Since the crack in the surface of the concrete acts as the main reason influencing the life span of the structure, regular inspections and maintenance are required. The sealing required for maintenance of the concrete surface is a method of repairing the crack in the surface in the beginning, and is effective in preventing additional cracks and expansion that occurs with time. However, sealing on large sized structures such as tall buildings or bottom parts of bridges are difficult to ensure safety of the workers due to inadequate working environments. Due to this reason, the importance of the need for sealing automation for the maintenance of large sized concrete structures is emerging. This study proposes two control methods to apply robot systems to the sealing of cracks on the bottom parts of concrete bridges. First is the method of automatically tracking the trajectory of cracks. The robot gets the trajectory of the cracks using video information obtained from cameras. Comparing the previous several points and new point, the next point can be estimated. Thus, the trajectory of the crack can be tracked automatically. The other method is sealing by maintaining steady force to the contacting surface. The concrete surface exposed to an external environment for a long time gets an irregular roughness. If robots are able to carry out sealing while maintaining a steady contact force on these rough surfaces, complete equal sealing can be maintained. In order to maintain this equal force, a force control method using impedance is proposed. This paper introduces two developed control methods to apply to sealing robots, and conducts a Lab Test and Field Test after applying to a robot. Based on the test results, opinions on the possibilities of field application of the robot applied with the control methods are presented.

• Atmosphere
• /
• v.19 no.2
• /
• pp.183-198
• /
• 2009

The purpose of this study is to summarize the tropical cyclone (TC) activity of 2008 over the western North Pacific including the verification of the official track and intensity forecast errors of these TCs. The TC activity - frequency, Normalized Typhoon Activity (NTA), and life span - was lower than 58-year (1951-2008) average. 22 tropical cyclones of tropical storm (TS) intensity or higher formed in the western North Pacific and the South China Sea in 2008. The total number is less than 58-year average frequency of 26.4. Out of 22 tropical cyclones, 11 TCs reached typhoon (TY) intensity, while the rest 11 TCs only reached severe tropical storm (STS) and tropical storm (TS) intensity - six STS and five TS storms. One typhoon KALMAEGI (0807) among them affected the Korea peninsula. However, no significant impact - casualty or property damage - was reported. On average of 22 TCs in 2008, the Korea Meteorological Administration (KMA) official track forecast error for 48 hours was 229 km. There was a big challenge for individual cyclones such as 0806 FENGSHEN and 0817 HIGOS presenting significant forecast error, with both intricate tracks and irregular moving speed. The tropical cyclone season in 2008 began in April with the formation of NEOGURI (0801). In May, four TCs formed in the western North Pacific in response to enhanced convective activity. On the other hand, the TC activity was very weak from June to August. It is found that the unusual anti-cyclonic circulation in the lower level and weak convection near the Philippines are dominant during summertime. The convection and atmospheric circulation in the western North Pacific contributed unfavorable condition for TC activity in the 2008 summertime. The 2008 TC activity has continued the below normal state since mid 1990s which is apparent the decadal variability in TC activity.

• Journal of the Korea Organic Resources Recycling Association
• /
• v.26 no.3
• /
• pp.55-61
• /
• 2018

This study evaluated if the selected samples meets the Solid Refuse Fuel quality criteria in Korea. Biomass and plastic wastes generated in D City were mixed in diverse ratio. When the biomass content was about 40%, the moisture content was close to the SRF criteria and was measured to be 9.8%. The ash contents were analyzed up to 4.19%, and the lower calorific values based on Steuer, Dulong Equation and Bomb Calorimeter were at least 4,851, 4,181 and 3,847 kcal/kg, respectively. As a result of the elemental analysis, sulfur and chloride content were measured up to 0.05%. Those values satisfied the SRF criteria. Also, heavy metals(Hg, Cd, Pb, As) were analyzed to be below the SRF criteria. This makes it possible to use efficiently the wood byproducts abandoned in the woods, and the physical properties of wood being weak to moisture can be supplemented with plastics. Consequently, if plastic and biomass were well mixed and made into SRF, it would overcome the problem of shortening the life span of incineration facilities due to the high temperature of plastic wastes in the incinerator.

• Korean Journal of Construction Engineering and Management
• /
• v.16 no.3
• /
• pp.68-77
• /
• 2015

One of recent concerns for super-tall buildings is how to manage hoisting plans and equipment efficiently. Disasters are frequently occurred in relation to electromotive hoists and cranes which are commonly used in construction sites. For construction lifts, particularly, it is highly important to conduct regular inspections or prepare against breakdown in terms of safety. However, unfortunately the reality is that regular inspections are only flatly conducted according to operating hours only. A lift, whose life span is subject to the complicated considerations such as operating hours, loading condition, and the like of each component, is far too invalid as a means of maintenance. As a way to resolve this problem and improve its convenience and safety for users, this study intends to calculate individual inspection interval for the main components of lifts by measuring their actual operating hours with sensing technology and analyzing their historical data. The findings of study include calculation of inspection intervals for the main components of lifts and classification of components to check by the actual operating hours of lift (40, 90, 130, 400 hours), which are drawn up into tables. This will make an opportunity to suggest efficient maintenance measures by enabling prevention of safety accidents and enhancement of safety for workers. Also, it will lead to increasing productivity of works by eliminating sources of delaying the term due to the breakdown of lifts.