• Microbiology and Biotechnology Letters
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• v.49 no.4
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• pp.528-533
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• 2021

The microalga, Tetrathelmis tetrathele, is used in the development of products for the aquaculture, food, and nutraceutical industries. In the present study, we investigated whether the T. tetrathele ethanolic extract (TTE), which has anti-inflammatory properties, can confer protection against alopecia and improve scalp health, influence the proliferation of human keratinocytes, HaCaT cells, and human hair follicle dermal papilla cells (HFDPC), or inhibit 5α-reductase activity. We found that TTE inhibited the production of the inflammatory mediator, nitric oxide (NO), and prostaglandin E₂ (PGE₂) without cytotoxicity in LPS-stimulated RAW 264.7 cells. In addition, TTE encouraged the proliferation of HaCaT cells and HFDPC. Our results showed that TTE had anti-inflammatory activities, proliferated HaCaT cells and HFDPC, and inhibited 5α-reductase activity. Therefore, we suggest that T. tetrathele could be a potent therapeutic agent for alopecia prevention and scalp improvement.

• Food Science and Industry
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• v.51 no.2
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• pp.157-164
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• 2018

Recently demand for safer and healthier food has augmented with advancements in health conditions. Food ingredients with yet to be known safety and functionality, are being investigated for their safety or detrimental effects. The Ministry of Food and Drug Safety has introduced "health functional food" by the "Health Functional Food Act" to evaluate bio-functional and safety properties of raw materials using standard methods including in-vitro and in-vivo testing before human consumption. Despite recent growth in net worth of domestic functional food market, most of the raw materials are not from local Korean industries with own research and development, and mostly terrestrial not marine resources. Geographically, Korea has access to diverse marine bio-resources that need to be managed and utilized sustainably. Recently, diverse novel physiologically active substances have been reported from marine organisms. Hence, the development of functional foods from marine bio-resources is considered as an inevitably important task.

• Journal of the Korea Institute of Military Science and Technology
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• v.21 no.5
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• pp.607-613
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• 2018

Hydraulic systems are widely used in the field of defense, construction machinery, agricultural machinery, and general industries, due to various advantages such as quick response speed and precision control. The defense equipments such as light rescue vehicle is operated in very harsh environments, so hydraulic components used in defense equipment are required to have very high reliability. In particular, hydraulic piston pump is very important component in a hydraulic systems, so life prediction of pump is essential. Therefore, in this study, we analyze the potential failure and the main failure mode of the hydraulic piston pump for the light rescue vehicle through the FMEA analysis, and predict the life of the pump by the accelerated life test considering the usage conditions.

• Journal of Life Science
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• v.15 no.2 s.69
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• pp.261-266
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• 2005

To figure out conserved genes in 66 microbial species and measuring the degree of conservation, analyses based on COG (Clusters of Orthologous Groups of proteins) algorithm were applied. Sixty-six microbial genomes, including three eukaryotes, hold 63 conserved orthologs in common. The majority $(82.5\%)$ of the conserved genes was related to translation, meaning the importance of protein in living creatures. Ribosomal protein S12 (COG0048) and L14 (COG0093) were more conserved genes than others from the distance value analysis. Phylogenetically related microbes grouped in genome analysis by average and standard deviation of 63 conserved genes. The 63 conserved genes, found in this research, would be useful in basic research and applied ones such as antibiotic development.

• Journal of the Korean Society of Safety
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• v.36 no.3
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• pp.7-14
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• 2021

Hybrid laminated Al/carbon-fiber-reinforced plastic (CFRP) composites are attracting considerable attention from industries such as aerospace and automobiles owing to their excellent specific strength and specific rigidity. However, when this material is used to fabricate high-pressure fuel storage containers subjected to repeated fatigue loads, fatigue life evaluation for the working load is regulated as an important criterion for operational safety and ease of maintenance. Among the existing evaluation methods for these vessels, the burst test and the hydraulic repeat test require expensive facilities. Thus, the present study aims to develop an improved fatigue life test for Al/CFRP laminated hybrid composites. The test specimen was manufactured using a curved mold considering the shape of a type III high-pressure storage container. The strain-life method was used for fatigue life evaluation, and the life was predicted based on the transition life. The results indicate that the more complex the CFRP stacking sequence, the longer is the transition life. This test method is expected to be useful for ensuring the fatigue safety and economy of hybrid laminate composites.

• Proceedings of the Safety Management and Science Conference
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• 2004.05a
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• pp.277-281
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• 2004

The establishment and application of risk management system is one of the current issues in world-wide leading companies. Poor risk management might bring large-scale accident in construction industry by its features(large scale, diversity). Standardization system and standard for risk should be managed timely. In this paper, we do comparative analysis of standardization systems and standards concerned on risk, so thus present basic data for safety reinforcement and risk zero in the construction life cycle process.

• Journal of the Korean Society for information Management
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• v.23 no.4 s.62
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• pp.89-110
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• 2006

Life science is one of the most important fields which have direct influence on human life. Many domestic life scientists in the industries, educational organizations and research institutes have been producing important results in a variety of forms such as papers, research notes, presentation materials, books and teaching materials. Open Archiving Community has been constructed in order to share and exchange research information related to life science between researchers. The domestic life scientists can acquire valuable information through the community quickly and efficiently. In this study, the community system has been designed and implemented to provide free access to all data including metadata registry of the bibliographic information on life science and research results accumulated by researchers of their own accord. The community system also has been designed and implemented based on Web 2.0 and provides users with BBS by subjects.

• Journal of Environmental Science International
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• v.31 no.3
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• pp.265-274
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• 2022

Lipoxygenase is an enzyme, mainly produced by plants, capable of converting unsaturated fatty acids to fatty acids. It has vast application potential in the food, pharmaceutical and agricultural industries. The aim of this study was to isolate novel lipoxygenase-producing bacteria from the environment and to investigate the lipoxygenase enzymatic properties for industrial production. The strain, NC1, isolated from cultivation soils, was identified as Bacillus subtilis based on the phenotypic characteristics and 16S rRNA gene sequencing. This strain formed a pink color around the colony when cultured on indamine dye formation plates. The production of lipoxygenase by B. subtilis NC1 was influenced by the composition of the medium and linoleic acid concentrations. The optimum temperature and pH for lipoxygenase activity was determined to be 40 ℃ and pH 6, respectively. The enzyme showed relatively high stability at temperatures ranging from 20-50 ℃ and acid-neutral regions. In addition, the lipoxygenase produced by B. subtilis NC1 was able to degrade commercially available oils including sunflower seed oil and Perilla oil. In this study, a useful indigenous bacterium was isolated, and the fundamental physicochemical data of bacterial lipoxygenase giving it industrial potential are presented.

• Food Science of Animal Resources
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• v.44 no.2
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• pp.443-463
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• 2024

This study investigated the impact of activated carbon, palm activated carbon, and zeolite on horse oil (HO) extracted from horse neck fat using supercritical fluid extraction with deodorant-untreated HO (CON) as a comparison. The yield and lipid oxidation of deodorant untreated HO (CON) were not significantly affected by the three deodorants. However, deodorant-treated HOs exhibited significantly elevated levels of α-linolenic acid (C18:3n3) and eicosenoic acid (C20:1n9) compared to CON (p<0.05), while other fatty acids remained consistent. Zeolite-purified HO demonstrated significantly lower levels of volatile organic compounds (VOCs) than other treatments (p<0.05). Remarkably, zeolite decreased the concentration of pentane, 2,3-dimethyl (gasoline odor), by over 90%, from 177.17 A.U. ×10⁶ in CON to 15.91 A.U. ×10⁶. Zeolite also effectively eliminates sec-butylamine (ammonia and fishy odor) as compared to other deodorant-treated HOs (p<0.05). Additionally, zeolite reduced VOCs associated with the fruity citrus flavor, such as nonanal, octanal, and D-limonene in HO (p<0.05). This study suggests that integrating zeolite in supercritical fluid extraction enhances HO purification by effectively eliminating undesirable VOCs, presenting a valuable approach for producing high-quality HO production in the cosmetic and functional food industries.

• Journal of Dairy Science and Biotechnology
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• v.33 no.4
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• pp.277-280
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• 2015

Acid- and acid/heat-coagulated cheese are cheeses made from direct acid- or acid/heat coagulation, consumed fresh without aging and have a soft texture. Despite of its short shelf-life, acid- and acid/heat-coagulated cheese are widely produced in all over the world due to their relatively easy manufacturing step and their popularity among consumers. Nowadays, acid- and acid/heat-coagulated cheese are used a lot as an ingredient of various foods as well. Therefore, understanding the characteristics of acid- and acid/heat-coagulated cheese is necessary to have more challenged application in food industries.