• Genes and Genomics
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• 제40권11호
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• pp.1199-1211
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• 2018

Soil acidification is one of major problems limiting crop growth and especially becoming increasingly serious in China owing to excessive use of nitrogen fertilizer. Only the STOP1 of Arabidopsis was identified clearly sensitive to proton rhizotoxicity and the molecular mechanism for proton toxicity tolerance of plants is still poorly understood. The main objective of this study was to investigate the transcriptomic change in plants under the low pH stress. The low pH as a single factor was employed to induce the response of the wheat seedling roots. Wheat cDNA microarray was used to identify differentially expressed genes (DEGs). A total of 1057 DEGs were identified, of which 761 genes were up-regulated and 296 were down-regulated. The greater percentage of up-regulated genes involved in developmental processes, immune system processes, multi-organism processes, positive regulation of biological processes and metabolic processes of the biological processes. The more proportion of down-regulation genes belong to the molecular function category including transporter activity, antioxidant activity and molecular transducer activity and to the extracellular region of the cellular components category. Moreover, most genes among 41 genes involved in ion binding, 17 WAKY transcription factor genes and 17 genes related to transport activity were up-regulated. KEGG analysis showed that the jasmonate signal transduction and flavonoid biosynthesis might play important roles in response to the low pH stress in wheat seedling roots. Based on the data, it is can be deduced that WRKY transcription factors might play a critical role in the transcriptional regulation, and the alkalifying of the rhizosphere might be the earliest response process to low pH stress in wheat seedling roots. These results provide a basis to reveal the molecular mechanism of proton toxicity tolerance in plants.

• 가족자원경영과 정책
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• 제22권4호
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• pp.17-32
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• 2018

The purpose of this study was to explore the effects of family life stress and family values on marital stability among middle-aged couples. The subjects included a total of 302 men and women aged 45-64 who had been married for more than 20 years and were living in Seoul. The collected data were statistically analyzed with the SPSS 21.0 Package. First, Cronbach's alpha was calculated to measure the reliability of the scale that assessed the variables of the research model. Then, mean and standard deviation were calculated to determine the degrees of family life stress, family values, and marital stability among the subjects. Finally, a hierarchical multiple regression analysis was performed to identify factors that affected the subjects' marital stability. The results revealed that the level of family life stress in middle-aged married men and women was slightly higher than the mean value. Of all the sub-scales of family life stress, the subjects were found to experience the most stress from factors related to financial pressure, followed by family relationships, a sense of loss within a family, and work-family compatibility. Therefore, financial problems were one of the critical stressors for middle-aged married couples. Also, for this demographic, the levels of family values and marital stability were higher than the medians. The factors affecting marital stability in middle-aged couples were identified to be family relationship stress, financial stress, subjective economic status, family values, stress related to work-familycompatibility,religion,andage.Thedegreeofmaritalstabilitywashigherinmiddle-agedcouplesa stheirstresslevelsfromfamilyrelationshipsandfinancialproblemswerelower.Moreover,thehigherthes ubjectiveeconomicstatusandthemoretraditionalthefamilyvalues,thehigherthedegreeofmaritalstabili ty.Finally,marriedcoupleswhowerereligioushadalowerlevelofstressfromwork-family compatibility, and the younger the couples, the higher the degree of marital stability.

• 문화기술의 융합
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• 제9권6호
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• pp.605-614
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• 2023

본 연구는 임상실습과 임상실습대체 교내실습 간의 간호대학생의 간호과정수행능력, 비판적사고성향, SBAR 기술지식의 차이를 비교하기 위해 시도되었다. 임상실습에 참여한 간호학과 3학년 학생 20명, 임상실습대체 교내실습에 참여한 학생 18명을 대상으로 자료를 수집하였다. 수집된 자료는 빈도와 백분율, 평균과 표준편차를 구하였고, t-test, ANOVA, 비모수 검정인 Mann-Whitney U-test, Kruskal Wallis test로 분석하였다. 연구결과 임상실습과 임상실습대체 교내실습 교육에 따른 간호대학생의 간호과정수행능력, 비판적사고성향, SBAR 기술지식 간에는 유의한 차이가 없었다. 임상실습에서 대학생활만족도가 높은 경우에 간호과정 수행능력과 SBAR 기술지식이 유의하게 높았고, 임상실습대체 교내실습에서는 간호학 만족도가 높은 경우에 비판적사고성향과 SBAR 기술지식이 높았고, 학점이 높을 때 비판적사고성향이 높았다. 향후 팬데믹 상황에 대비하여 간호과정 수행능력과 비판적사고성향 및 SBAR 기술지식 능력을 향상시킬 수 있는 체계화된 임상실습대체 실습교육 방안이 마련되어져야 할 것이다.

• 여성건강간호학회지
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• 제3권1호
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• pp.82-92
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• 1997

The purpose of this study was attempted to understand the substance and meaning of menopause experienced by women through informal interviews with oral consent. The informants were 6 perimenopausal women of 50-55 years old who are executing menopause. Colaizz's analytical method, a type of phenomenological analysis, was used to analyze data recorded by audiotape. One professor and a master's degree student who understand phenomenology, and the one who has a master of arts examined the validity between the meanings composed of the clusters of themes. Findings were turned out to be valid through validation process as the last step. The meaning of menopause implied both 'concept about menopause' and 'menopause as a time of change'. Menopause was mostly considered as cessation of menstruation as a physiological, natural, and normal process by aging. However, some people regarded menopause as a loss of youth and womanhood and lessening of every function of the body. Menopause as the time of changes means 'the period of' 'hormonal changes' such as change of menstruation, hot flushes, perspiration, and palpitation ; 'body function changes' of visual acuity, physical strength, sleeping, digestion, thoughts, bone and joints, skin sensibility, sexual pattern and intelligence ; 'emotional changes' such as anxiety, loneliness, gloominess, and nervousness. Menopause is a turning point on the women's life cycle accompanying various kind of changes and health problems. Therefore it is inevitable to develop strategy helping menopausal women pass through the critical successfully by adapting and coping with their critical period toward the healthy and better quality of life individually rather than putting them all into the standardized hormonal replacement protocol.

• 한국환경농학회지
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• 제41권3호
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• pp.153-157
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• 2022

BACKGROUND: The residue dissipation pattern of pesticides for agricultural products during the pre-harvest period after the final application is important to prevent the maximum residue limit (MRL) violations in domestic and export markets. The MRL violations of carbendazim are observed more often in chamnamul by pesticide residue management surveys by the Ministry of Food and Drug Safety. The residue level at the pre-harvest interval (PHI) and the residue dissipation constant from the critical good agricultural practice (cGAP) trials could be estimated to meet the MRL and pose a health risk to consumers. METHODS AND RESULTS: Chamnamuls were harvested at 0, 1, 3, 5, 7, 10, and 14 days after application of carbendazim in accordance with critical GAP. The residue analysis in chamnanul was performed by HPLC-DAD with the C₁₈ column. The limit of quantitation of carbendazim was 0.04 mg/kg, and the recoveries were 74.4 - 95.8% at the two spiked levels (LOQ and 10LOQ) of carbendazim. The dissipation rates in chamnamul were calculated from the residues at the sampling days by statistical method at a 95% confidence level. The biological half-lives of residual carbendazim in the field trials 1 and 2 were 4.9 and 4.4 days, respectively. CONCLUSION(S): In this dissipation study, the residue concentrations at the recommended PHI were higher than the established MRL in Korea. Therefore, the MRL is proposed based on the residue data sets from the trials conducted at the same cGAP and the dietary exposure assessment.

• 동력기계공학회지
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• 제16권1호
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• pp.12-18
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• 2012

The fluid performance is one of the key design factors considered during the development of torque converters especially at conceptual design stages. Therefore the design environment that allows an easy access to legacy data of fluid performance could be critical to reduce the design life cycle as well as to increase the performance of the torque converter. In this paper we present a computer-based system that enables designers to utilize massive legacy data for their design of torque converters. For the implementation of the system we propose a standard format for the legacy data and build them into the database to be efficiently shared by designers in the company. Also we provide numerous analysis tools in the system that allow, for example, database management, data viewing and document generation for search, analysis and reporting. In the paper the implementation of the system is introduced in detail with its effective user interface.

• 한국기계가공학회지
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• 제19권11호
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• pp.87-93
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• 2020

A key component of aviation safety is to eliminate the errors in commercial aircraft air data systems to ensure stable aviation operation. Although the technical aspects such as the maintenance and inspection play a pertinent role, human errors are expected to have a similar or even larger influence on the aviation safety. Aviation maintenance and inspection tasks are often performed by a complex organization, in which individuals perform a variety of tasks in an environment involving time pressure, sparse feedback, and complex conditions. These situational characteristics, combined with the general tendency of human error, may lead to various types of errors, which may have critical consequences such as accidents and loss of life. For instance, if an amber message "IAS DISAGREE" is displayed on the primary flight display while the aircraft is rolling on the runway to takeoff, the crew immediately performs a rejected takeoff operation and troubleshoots the air data system. This paper proposes alternative approaches to address the occurrence of defects due to the human factors involved in the practical processes of the air data system of commercial aircraft.

• 한국균학회소식:학술대회논문집
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• 한국균학회 2015년도 춘계학술대회 및 임시총회
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• pp.59-59
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• 2015

Cryptococcus neoformans causes life-threatening meningoencephalitis in humans, but the treatment of cryptococcosis remains challenging. To develop novel therapeutic targets and approaches, signaling cascades controlling pathogenicity of C. neoformans have been extensively studied but the underlying biological regulatory circuits remain elusive, particularly due to the presence of an evolutionarily divergent set of transcription factors (TFs) in this basidiomycetous fungus. In this study, we constructed a high-quality of 322 signature-tagged gene deletion strains for 155 putative TF genes, which were previously predicted using the DNA-binding domain TF database (http://www.transcriptionfactor.org/). We tested in vivo and in vitro phenotypic traits under 32 distinct growth conditions using 322 TF gene deletion strains. At least one phenotypic trait was exhibited by 145 out of 155 TF mutants (93%) and approximately 85% of the TFs (132/155) have been functionally characterized for the first time in this study. Through high-coverage phenome analysis, we discovered myriad novel TFs that play critical roles in growth, differentiation, virulence-factor (melanin, capsule, and urease) formation, stress responses, antifungal drug resistance, and virulence. Large-scale virulence and infectivity assays in insect (Galleria mellonella) and mouse host models identified 34 novel TFs that are critical for pathogenicity. The genotypic and phenotypic data for each TF are available in the C. neoformans TF phenome database (http://tf.cryptococcus.org). In conclusion, our phenome-based functional analysis of the C. neoformans TF mutant library provides key insights into transcriptional networks of basidiomycetous fungi and ubiquitous human fungal pathogens.

• 한국인터넷방송통신학회논문지
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• 제16권4호
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• pp.109-115
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• 2016

라이프로그는 개인차원에서 일상생활을 오랫동안 기억하거나 공유하기위한 단순한 기록목적으로 시작되었지만 최근 다양한 기업들이 각각의 전문성을 활용한 분석방법을 도입함으로써 개인의 삶의 질이 향상되는 새로운 라이프로 그 비즈니스가 형성되고 있다. 이러한 중요한 장점에도 불구하고 개인 건강 라이프로그 서비스는 데이터의 보안에 관련된 사용자 입장에서는 피할 수 없는 중요한 도전을 제기하고 있다. 개인 건강 라이프로그 서비스가 활성화되면서 사용자 개인정보 침해가 발생하고 사용자의 민감한 의료정보가 유출되는 문제가 증가되고 있다. 본 논문에서는 개인 건강 라이프로그 서비스를 위한 보안 참조모델을 제시하고자 한다. 제안된 보안 참조모델은 건강 라이프로그 서비스 제공을 위한 개인 정보 보호 방안에 명확한 지침을 제시하여 관련 분야의 산업 활성화 및 신 시장 개척을 이끌어 낼 수 있을 것으로 예상된다.

• Journal of the Korean Wood Science and Technology
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• 제20권2호
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• pp.61-72
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• 1992

This study was carried out to investigate the fracture behavior and the fracture criterion of yellow lauan(Shorea spp.), when has used for furniture and wood structures, and to offer a reliability for wood structure and basic data for wood fracture criterion in experiments which are fracture tested under mode I, mode II and mixed mode loading condition. The results were summarized as follows; 1. Fractures in specimens which have inclined grain in yellow lauan procedeed from crack tip in the radial direction along the grain. 2. In yellow lauan, $K_{IC}RL$ was 42.1kg/$cm^{3/2}$ and $K_{IIC}RL$ was 15.8kg/$cm^{3/2}$. 3. The fracture criteria of lauan were; ($K_I/K_{IC}$)+($K_{II}/K_{IIC}$)=1 in RL system with inclined grain at $45^{\circ}$, ($K_I/K_{IC}$)+$(K_{II}/K_{IIC})^2$=1 with inclined grain at $15^{\circ}$ and $(K_I/K_{IC})^2$+$(K_{II}/K_{IIC})^2$=1 with inclined grain at $30^{\circ}$, $60^{\circ}$, $75^{\circ}$ and $90^{\circ}$, respectively. 4. The fracture criterion of wood could vary with the species, and the load applying condition. In order to measure the fracture criterion strictly, along with standardization of specimen geometry a large amount of experimental data is needed. 5. $K_{IC}$(critical stress intensity factor) can be predicted by grain angle. As the grain inclined angle increased, $K_{IC}$ and $K_{IIC}$ are increased.