• Bioinformatics and Biosystems
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• v.1 no.2
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• pp.99-102
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• 2006

The Basic Local Alignment Search Tool (BLAST) is one of the most established software in bioinformatics research and it compares a query sequence against the libraries of known sequences in order to investigate sequence similarity. Expressed Sequence Tags (ESTs) are single-pass sequence reads from mRNA (or cDNA) and represent the expression for a given cDNA library and the snapshot of genes expressed in a given tissue and/or at a given developmental stage. Therefore, ESTs can be very valuable information for functional genomics and bioinformatics researches. Although major bio database (DB) websites including NCBI are providing BLAST services and EST data, local DB and search system is demanding for better performance and security issue. Here we present animal EST DBs and local BLAST search system. The animal ESTs DB in NCBI Genbank were divided by animal species using the Perl script we developed. and we also built the new extended DB search systems fur the new data (Local Animal BLAST Search System: http://bioinfo.kohost.net), which was constructed on the high-capacity PC Cluster system fur the best performance. The new local DB contains 650,046 sequences for Bos taurus(cattle), 368,120 sequences for Sus scrofa (pig), 693,005 sequences for Gallus gallus (fowl), respectively.

• Journal of Internet Computing and Services
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• v.21 no.1
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• pp.45-55
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• 2020

Due to the development of information and communication technology, the number of new / variant malicious codes is increasing rapidly every year, and various types of malicious codes are spreading due to the development of Internet of things and cloud computing technology. In this paper, we propose a malware analysis method based on string information that can be used regardless of operating system environment and represents library call information related to malicious behavior. Attackers can easily create malware using existing code or by using automated authoring tools, and the generated malware operates in a similar way to existing malware. Since most of the strings that can be extracted from malicious code are composed of information closely related to malicious behavior, it is processed by weighting data features using text mining based method to extract them as effective features for malware analysis. Based on the processed data, a model is constructed using various machine learning algorithms to perform experiments on detection of malicious status and classification of malicious groups. Data has been compared and verified against all files used on Windows and Linux operating systems. The accuracy of malicious detection is about 93.5%, the accuracy of group classification is about 90%. The proposed technique has a wide range of applications because it is relatively simple, fast, and operating system independent as a single model because it is not necessary to build a model for each group when classifying malicious groups. In addition, since the string information is extracted through static analysis, it can be processed faster than the analysis method that directly executes the code.

• Journal of Microbiology and Biotechnology
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• v.14 no.3
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• pp.584-592
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• 2004

A thermostable $\beta$-glycosidase gene, tfi $\beta$-gly, was cloned from the genomic library of Thermus filiformis Wai33 A1. ifi $\beta$-gly consists of 1,296 bp nucleotide sequence and encodes a polypeptide of 431 amino acids. It shares a strong amino acid sequence similarity with the $\beta$-glycosidases from other Thermus spp. belonging to the glycosyl hydrolase family 1. In the present study, the enzyme was overexpressed in Escherichia coli BL21 (DE3) using the pET21b(+) vector system. The recombinant enzyme was purified to homogeneity by heat treatment and a $Ni^{2+}$-affinity chromatography. Polyacrylamide gel electrophoresis (PAGE) showed that the recombinant Tfi $\beta$-glycosidase was a monomeric form with molecular mass of 49 kDa. The temperature and pH range for optimal activity of the purified enzyme were 80- $90^{\circ}C$ and 5.0-6.0, respectively. Ninety-three percent of the enzyme activity was remained at $70^{\circ}C$ after 12 h, and its half-life at $80^{\circ}C$ was 6 h, indicating that Tfi $\beta$-glycosidase is highly thermostable. Based on its K_m$, or $K_{cat}K_m$, ratio, Tfi $\beta$-glycosidase appeared to have higher affinity for $\beta$-D-glucoside than for $\beta$-D-galactoside, however, $K_{cat} for \beta$-D-galactoside was much higher than that for $\beta$-D-glucoside. The activity for lactose hydrolysis was proportionally increased at $70^{\circ}C$ and pH 7.0 without substrate inhibition until reaching 250 mM lactose concentration. The specific activity of Tfi TEX>$\beta$-glycosidase on 138 mM lactose at $70{^\circ}C$ and pH 7.0 was 134.9 U/mg. Consequently, this newly cloned enzyme appears to have a valuable advantage of conducting biotechnological processes at elevated temperature during milk pasteurization in the production of low-lactose milk.

• Journal of Information Management
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• v.41 no.4
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• pp.227-249
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• 2010

Scholarly information has increased tremendously according to the development of IT, especially the Internet. However, simultaneously, people have to spend more time and exert more effort because of information overload. There have been many research efforts in the field of expert systems, data mining, and information retrieval, concerning a system that recommends user-expected information items through presumption. Recently, the hybrid system combining a content-based recommendation system and collaborative filtering or combining recommendation systems in other domains has been developed. In this paper we resolved the problem of the current recommendation system and suggested a new system combining collaborative filtering and Naive Bayes Classification. In this way, we resolved the over-specialization problem through collaborative filtering and lack of assessment information or recommendation of new contents through Naive Bayes Classification. For verification, we applied the new model in NDSL's paper service of KISTI, especially papers from journals about Sitology and Electronics, and witnessed high satisfaction from 4 experimental participants.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.40 no.3
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• pp.159-168
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• 2022

Local governments should try to resolve the inequality of living SOC (Social Overhead Capital) and construct spatial information on the location of living SOCs and optimal locations. This study analyzed the accessibility, equity, and optimal location of the living SOC, considering the research needs related to the living SOC. The target facility is core living facilities(a public library, a park, a culture center, and a public daycare center). The analysis area is Suwon city in Gyeonggi province, and the base year of the analysis is 2020. The study calculated accessibility per population in a microscopic neighborhood living area(200m×200m). The Gini coefficient was used to identify the regional disparity in accessibility among Dong regions. The optimal location was explored with the Maximal Covering Location Problem theory. As a result, spatial accessibility of facilities except for public daycare centers revealed a large gap between regions. Areas with excellent accessibility also showed significant variations in the facilities. The regional disparity in living SOC was the largest in culture centers, followed by parks, public daycare centers, and public libraries. The optimal locations for public libraries, parks, and culture centers are concentrated in the old downtown, while those of public daycare centers are found throughout Suwon city. The results of this study are the crucial contents of spatial planning for SOC supply in local governments. Therefore, follow-up studies will be able to refer to the analysis structure and results of the study.

• The Journal of the Korea Contents Association
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• v.16 no.8
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• pp.580-591
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• 2016

The purpose of this study was to review articles and theses on adjustment of college freshmen from domestic researches conducted during the past 11 years, to identify overall research trends, and to suggest direction and strategies for college freshman's adjustment. The final 24 articles were selected from three databases, RISS, KISS, and NAL (National assembly library) using specific inclusion criteria. Twenty were correlation studies and four were experimental studies. In 2009, the first study on adjustment of college freshmen was published. Since then several more studies have been conducted to date. This means that people have recognized the importance of adjustment of college freshmen. Twenty three studies that are reviewed used Baker and Siryk's college adjustment tool. From reviewed correlation studies, mean score of college students' adjustment was 3.25. The related variables with adjustment of college freshmen revealed 20 items, especially self-esteem, self-efficacy, and stress showed important related concepts. The general characteristics related to adjustment of freshmen were outgoing character, living with family, aged students, satisfied with the area of study, and satisfied with school life. The findings of this study indicated that colleges when planning for the freshmen orientation program should focus on improving self-efficacy of students, stress management, mentor program, and freshmen adjustment program for each department of the school and college.

• Journal of the Korean Society for information Management
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• v.4 no.2
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• pp.31-46
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• 1987

The United Kingdom has a well-developed and comprehensive information infrastructure which has grown up over many years, but in the strict sense it has no coherent body of policy relating to information collection, storage, provision and supply. However, each of the governmental, professional and other bodies which has any major involvement with information, has committees to run its affairs and develop its policies in relation to issues and problems in the field. In addition, a number of ad hoc committees and working parties, to discuss or deal with a current problem, or to monitor or advise on the conduct of a research or development project, show that there is a high degree of awareness. of what is happening in the field and that there are many opportunities for expressing any particular point of view. The need for good intelligence in business or industrial operations is now being more generally accepted, and in consequence the need for a director of intelligence is also seen. The director of information in an industrial setting is the information manager, who combines or has access to the skills of several disciplines, including library, data processing and communication skills as well as managerial. Recognition of the need for such persons has policy implications in terms of short-term training provision and long-term educational facilities for the emerging profession, as well as manpower planning implications.

• Journal of Acupuncture Research
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• v.35 no.4
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• pp.158-168
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• 2018

The purpose of this study was to review clinical studies of lumbar herniated intervertebral disc (LHIVD) treatment using acupuncture. Online database (PubMed, COCHRANE Library, EMBASE, CNKI, KISS, NDSL, KoreaMed, KMbase, OASIS, and KISTI) searches were conducted in May 2018. Studies that used acupuncture, electroacupuncture or warm needle acupuncture were included, along with participants who had lower back pain and radiating pain of their lower limbs consistent with radiological findings. Animal studies and nonclinical data were excluded. Data on treatment methods, site, time, frequency, period, and scales used were analyzed. There were 69 studies including 38 randomized controlled trials, 14 retrospective observational studies, and 17 clinical case studies. There were 51 acupoints selected for acupuncture treatment of LHIVD. The most frequently treated acupoints were BL23, BL25, BL24, and BL40. The mean treatment time, frequency, and duration were $26.06{\pm}6.70$ mins, $6.29{\pm}1.70$ times/week, and $20.57{\pm}11.04$ days, respectively, in randomized controlled trials (RCT), and $18.62{\pm}4.60$ mins, $11.58{\pm}3.99$ times/week, and $34.43{\pm}17.62$ days, respectively, in case/retrospective studies ($mean{\pm}SD$). This review collates information about acupuncture treatment methods for LHIVD.

• 재활복지
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• v.21 no.2
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• pp.191-216
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• 2017

Recently, according to demands for a mobility right of people with disabilities, the use of powered mobility device has been rapidly increased and recharging facilities have been set up in many places of country. But the standards for the installation and management of the facilities are not clear and many problems are brought up in operating the facilities. Therefore, regulations and realities of recharging facilities were investigated and the user survey was progressed. On the basis of the research results, a rational and efficient installation and management plan was drawn up. The plan suggests that the recharging facilities should be installed in a building managed by government and many kinds of public building like library, theater, sports facilities, department store, museum, etc. Further, the recharging facilities should secure independent place which have specified area for protecting of privacy and provide some amenities for people with disabilities to enhance the conveniences.

• Journal of Digital Convergence
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• v.19 no.8
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• pp.33-42
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• 2021

As smartphone-based tourism platforms have become active, policy establishment and service enhancement using review data are being made in various fields. In the case of the preceding studies using tourism review data, most of the studies centered on domestic tourists were conducted, and in the case of foreign tourist studies, studies were conducted only on data collected in some languages and text mining techniques. In this study, 3,515 review data written by foreigners were collected by designating the "Daegu attractions" keyword through the online review site. And LDA-based topic modeling was performed to derive tourism topics. The spatial approach through global and local spatial autocorrelation analysis for each topic can be said to be different from previous studies. As a result of the analysis, it was confirmed that there is a global spatial autocorrelation, and that tourist destinations mainly visited by foreigners are concentrated locally. In addition, hot spots have been drawn around Jung-gu in most of the topics. Based on the analysis results, it is expected to be used as a basic research for spatial analysis based on local government foreign tourism policy establishment and topic modeling. And The limitations of this study were also presented.