• Journal of Ginseng Research
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• v.45 no.3
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• pp.371-379
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• 2021

Mitochondrial dysfunction contributes to the pathogenesis and prognosis of many common disorders, including neurodegeneration, stroke, myocardial infarction, tumor, and metabolic diseases. Ginsenosides, the major bioactive constituents of Panax ginseng (P. ginseng), have been reported to play beneficial roles in the molecular pathophysiology of these diseases by targeting mitochondrial dysfunction. In this review, we first introduce the types of ginsenosides and basic mitochondrial functions. Then, recent findings are summarized on different ginsenosides targeting mitochondria and their key signaling pathways for the treatment of multiple diseases, including neurological disorders, cancer, heart disease, hyperglycemia, and inflammation are summarized. This review may explain the common targets of ginsenosides against multiple diseases and provide new insights into the underlying mechanisms, facilitating research on the clinical application of P. ginseng.

• Advances in nano research
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• v.13 no.3
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• pp.233-245
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• 2022

Resently, the use of smart structures has been heightened up rapidly. For this issue, vibration analysis related to a graphene nanoplatelet composite (GPLRC) nanodisk which is attached to a piezoelectric layer and is subjected to thermal loads is explored in the current paper. The formulation of this study is obtained through the energy method and nonlocal strain gradient theory, and then it is solved employing generalized differential quadrature method (GDQM). Halpin-Tsai model in addition to the mixture's rule are utilized to capture the material properties related to the reinforced composite layer. The compatibility conditions are presented for exhibiting the perfect bounding between two layers. The results of this study are validated by employing the other published articles. The impact of such parameters as external voltage, the radius ratio, temperature difference, and nonlocality on the vibrational frequency of the system is investigated in detail.

• Progress in Superconductivity and Cryogenics
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• v.10 no.2
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• pp.27-29
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• 2008

Superconducting RF cavities are being considered for accelerating a proton beam at 700 MHz in the linac of the Proton Engineering Frontier Project (PEFP) and its post-project. Dumbbell fabrication is a mid-process for manufacturing an elliptical superconducting RF cavity. During the dumbbell fabrication, control of the dumbbell length and the $TM010\;{\pi}$ mode frequencies is necessary to build up a desired cavity. A new formula with a perturbation measurement method is used to measure and calculate the frequencies of the individual half-cells of a PEFP low-beta dumbbell, and to tune the frequency and length of the half-cells. In this article, the tuning method and results of the PEFP low-beta dumbbells have been presented.

• Journal of information and communication convergence engineering
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• v.21 no.2
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• pp.152-158
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• 2023

In recent years, as computer-generated imagery has been applied to more industries, realistic facial animation is one of the important research topics. The current solution for realistic facial animation is to create realistic rendered 3D characters, but the 3D characters created by traditional methods are always different from the actual characters and require high cost in terms of staff and time. Deepfake technology can achieve the effect of realistic faces and replicate facial animation. The facial details and animations are automatically done by the computer after the AI model is trained, and the AI model can be reused, thus reducing the human and time costs of realistic face animation. In addition, this study summarizes the way human face information is captured and proposes a new workflow for video to image conversion and demonstrates that the new work scheme can obtain higher quality images and exchange effects by evaluating the quality of No Reference Image Quality Assessment.

• Proceedings of the Korean Society of Computer Information Conference
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• 2021.07a
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• pp.709-711
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• 2021

본 연구의 목적은 국경 간 전자상거래 플랫폼의 지속이용의도의 영향을 파악하며 국경 간 전자상거래 플랫폼의 발전에 의의를 규명할 것이다. 국내 전자상거래에 비해, 국경 간 전자상거래는 문화 차이, 언어 차이, 법률 차이, 통관 처리, 국경 간 물류 등의 문제로 인해 더 높은 불확실성을 가지고 있다. 소비자의 지속이용의도에 관한 연구는 국내 전자상거래의 연구에 머물러, 국경 간 전자상거래 플랫폼이 많은 도전에 직면하게 된다. 국경 간 전자상거래 플랫폼의 어떤 요인이 소비자의 구매 의도에 영향을 미치는지 연구하면, 국경 간 전자상거래 기업의 플랫폼에 상응하는 개선을 돕고, 국경 간 전자상거래 기업의 발전을 촉진하며, 이를 통해 대외무역의 발전을 촉진 할 것이다. 특히 한국 중소업체 입장에서는 이를 통해 한국 제품을 직접 수출의 주역으로 자리 잡으며 육박하는 수출을 견인한 것으로 추정될 수 있다.

• Kyungpook Mathematical Journal
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• v.63 no.2
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• pp.199-223
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• 2023

We introduce the constants E[t, X], C_NJ[X] and J[t, X] to describe the asymmetry of the norm. They can be seen as the skew version of the Gao's parameter, von Neumann-Jordan constant and Milman's moduli, respectively. We establish basic properties of these constants, relating them other well known constants, and use these properties to calculate the constants for specific spaces. We then use these constants to study Hilbert spaces, uniformly non-square spaces and their normal structures. With the Banach-Mazur distance, we use them to study isomorphic Banach spaces.

• Proceedings of the Korean Society of Computer Information Conference
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• 2022.07a
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• pp.713-715
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• 2022

Video learning through YouTube has emerged as one of the most widely used instructional methods, yet relatively little research has been conducted on YouTube video users' willingness to use or behavior, so it is important to examine how to make and keep users' willingness to continue learning and to improve their retention rate for effective online learning. With reference to perceived value theory and utilizing an ECM perspective, the authors construct a model of YouTube video continuous learning intention and investigate the influence of perceived value and satisfaction on users' willingness to use YouTube videos for continuous learning.

• Korean Journal of Radiology
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• v.21 no.5
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• pp.545-549
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• 2020

The 2019 novel coronavirus (2019-nCoV) outbreak in Wuhan, Hubei Province, China in 2019 led to large numbers of people being infected and developing atypical pneumonia (coronavirus disease 2019, COVID-19). Typical imaging manifestations of patients infected with 2019-nCoV has been reported, but we encountered an atypical radiological manifestation on baseline computed tomography (CT) images in three patients from Wuhan, China infected with the 2019-nCoV. Surprisingly, the only similar CT finding was a solitary sub-centimeter ground-glass nodule adjacent to bronchovascular bundles, which could be easily overlooked. In addition, the follow-up images in these patients showed how COVID-19 pneumonia evolved from these small nodules. The radiologic manifestation of the three cases will expand contemporary understanding of COVID-19.

• Bulletin of the Korean Chemical Society
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• v.34 no.3
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• pp.827-830
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• 2013

Investigation of an organic extract of the fruits Schisandra wilsoniana led to the isolation of two new highly oxygenated nortriterpenoids, named schilancidilactones V-W (1-2). Their structures were elucidated by spectroscopic evidence. Compounds 1-2 feature a double bond between C-7 and C-8 compared with related known nortriterpenoids isolated from the genus Schisandra. Compounds 1 and 2 were tested for their anti-HIV-1 activities and cytotoxicity. The results revealed that compounds 1 and 2 showed moderate anti-HIV-1 activities with $EC_{50}$ 3.05 and 2.87 ${\mu}g/mL$, respectively, and compound 1 showed high cytotoxicity against KB and MDA-MB-231 cell with $IC_{50}$ values of 3.18 and 5.22 ${\mu}M$, respectively.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3605-3609
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• 2012

Lung cancer seriously threatens human health, so it is important to investigate gene expression changes in affected individuals in comparison with healthy people. Here we compared the gene expression profiles between smokers with and without lung cancer. We found that the majority of the expressed genes (threshold was set as 0.1 RPKM) were the same in the two samples, with a small portion of the remainder being unique to smokers with and without lung cancer. Expression distribution patterns showed that most of the genes in smokers with and without lung cancer are expressed at low or moderate levels. We also found that the expression levels of the genes in smokers with lung cancer were lower than in smokers without lung cancer in general. Then we detected 27 differentially expressed genes in smokers with versus without lung cancer, and these differentially expressed genes were foudn to be involved in diverse processes. Our study provided detail expression profiles and expression changes between smokers with and without lung cancer.