• Journal of Korean Neurosurgical Society
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• v.50 no.2
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• pp.89-94
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• 2011

Objective : D-dimer is a breakdown product of fibrin mesh after factor XIII stabilization. Previously, many authors have demonstrated a relationship between D-dimer level and stroke progression or type. This study aimed to investigate the relationship between D-dimer level and stroke volume. Methods : Between January 2008 and December 2009, we analyzed the D-dimer levels of 59 acute ischemic stroke patients in our neurosurgical department both upon admission and after seven days of initial treatment. Each patient's National Institute of Health Stroke Scale score, modified Rankin Scales score, Glasgow outcome score, and infarction volume were also evaluated. Results : Mean D-dimer level at admission was 626.6 ${\mu}g/L$ (range, 77-4,752 ${\mu}g/L$) and the mean level measured after seven days of treatment was 238.3 ${\mu}g/L$ (range, 50-924 ${\mu}g/L$). Mean D-dimer level at admission was 215.3 ${\mu}g/L$ in patients with focal infarctions, 385.7 ${\mu}g/L$ in patients with multiple embolic infarctions, 566.2 ${\mu}g/L$ in those with 1-19 cc infarctions, 668.8 ${\mu}g/L$ in 20-49 cc infarctions, 702.5 ${\mu}g/L$ in 50-199 cc infarctions, and 844.0 ${\mu}g/L$ in >200 cc infarctions (p=0.044). On the 7th day of treatment, the D-dimer levels had fallen to 201.0 ${\mu}g/L$, 293.2 ${\mu}g/L$, 272.0 ${\mu}g/L$, 232.8 ${\mu}g/L$, 336.6 ${\mu}g/L$, and 180.0 ${\mu}g/L$, respectively (p=0.530). Conclusion : Our study shows that D-dimer level has the positive correlation with infarction volume and can be use to predict infarction-volume.

• Journal of Nutrition and Health
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• v.49 no.1
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• pp.28-35
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• 2016

Purpose: Vitamin D status is associated with several chronic diseases related to obesity. In this study, we evaluate the nutritional status of vitamin D and its relation to obesity indices in Korean women. Methods: A total of 156 healthy women participated. Vitamin D status (serum $25-OH-vitamin\;D_3$ level) and obesity indices (body mass index, body fat mass, waisthip ratio, and body fat percentage etc.) and serum lipid profiles and serum adipokine (leptin and adiponectin) levels were analyzed. Results: The $25(OH)D_3$ level showed an extremely skewed distribution from 4.1 ng/ml to 24.4 ng/ml and mean $25(OH)D_3$ level was $9.0{\pm}4.0ng/ml$. With cut-off level for vitamin D deficiency (< 12.0 ng/ml), insufficiency (12-19.9 ng/ml) and sufficiency (${\geq}20ng/ml$), 77.6%, 19.2%, and 3.2% of subjects showed vitamin D deficiency, insufficiency, and sufficiency status, respectively. The $25(OH)D_3$ level showed positive correlation with weight (r = 0.2461, p < 0.01), body mass index (r = 0.2913, p < 0.001), body fat contents (r = 0.1691, p < 0.05), fat free mass (r = 0.2330, p < 0.01), and waist hip ratio (r = 0.1749, p < 0.05) after adjusted by age. The $25(OH)D_3$ level showed no significant correlation with serum lipid profiles and adipokine levels. Conclusion: Most subjects (76.6%) in this study, who had a vitamin D deficient status and serum $25(OH)D_3$ level, showed positive correlation with several obesity indices, however further research based on a large Korean population is needed to confirm the relationship.

• Journal of Korea Game Society
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• v.8 no.4
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• pp.87-93
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• 2008

The game engine has executed an application after making a mobile 3D game engine which is based on mobile 3D standard graphic API using openGL-ES so far. But, We could not do it satisfactorily that contents compatibility of various types as a various low-level's function is supported. At this point, This study introduce a mobile 3D game engine which is based on mobile 3D standard graphic API using JSR-184 that supporting a high-level's API more than openGL-ES and optimizing to Java environment on J2ME in the center of GSM phone. Also, We shows that the proposed skinned-mesh scheme for enhancing the process speed of a 3D object on JSR-184 engine. The experimental results are shown.

• Proceedings of the Technology Innovation Conference
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• 2003.06a
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• pp.26-40
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• 2003

Korean enterprises have increased their R&D efforts to a large scale since the 1990s, especially after IMF jurisdiction period. The number of research institutes and R&D resources increased sharply. In line with the increase of R&D efforts, this paper investigates how well Korean firms manage R&D capabilities. According to our analysis, Korean enterprises adopt about the 2.3th to 2.7th generation of R&D management. In spite of insufficient R&D resources, Korean SMEs adopt a similar level of R&D management practice to that of big firms. However, some big enterprises have already adopted the 4th generation of R&D management. Also, many SMEs adopt a much lower level of R&D management than average level. In this sense, it is necessary to make an in-depth study on firms'R&D management capabilities by utilizing various factors of R&D generation model.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2018.05a
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• pp.37-38
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• 2018

BIM(Building Information Modeling) in the architecture, VDC(Virtual Design and Construction) defined CIFE(Center for Integrated Facility Engineering) of Stanford university in USA, and Data-driven design definition issued by TECDOC-1284 of IAEA are doing data-level design generated by 3D CAD technology, integrating and managing related information based on the 3D model, and Using 3D models effectively during nuclear power plant life cycle. 3D model of domestic nuclear power industry is using interference review between design fields, 4D system linked 3D construction model and schedule activity, but the 3D model generated in the design phase is effectively not utilized during the construction, operation, decommissioning. therefore, This study is aimed to suggest 3D model LOD(Level of Detail) advancement method through the analysis of existing literature, 2D drawings, and 3D models throughout nuclear power plant lifecycle.

• Nuclear Engineering and Technology
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• v.53 no.1
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• pp.30-43
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• 2021

In the 2D/1D method, a global adjoint CMFD based on the generalized equivalence theory is built to synthesize the 2D radial MOC adjoint and 1D axial NEM adjoint calculation and also to accelerate the iteration convergence of 3D whole-core adjoint transport calculation. Even more important, an advanced yet accurate two-level (TL) CMFD acceleration technique is proposed, in which an equivalent one-group adjoint CMFD is established to accelerate the multi-group adjoint CMFD and then to accelerate the 3D whole-core adjoint transport calculation efficiently. Based on these method, a new code is developed to perform 3D adjoint neutron flux calculation. Then a set of VERA and C5G7 benchmark problems are chosen to verify the capability of the 3D adjoint calculations and the effectiveness of TL CMFD acceleration. The numerical results demonstrate that acceptable accuracy of 2D/1D adjoint calculations and superior acceleration of TL CMFD are achievable.

• Korean small business review
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• v.42 no.4
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• pp.147-172
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• 2020

This study presents the determinants of R&D efficiency as the focus on CEO's competency, which influences R&D competency and R&D efficiency. The research samples are 6,708 technology-innovation small and medium-sized enterprises (SMEs). The independent variable is the R&D competency(existence of R&D organization, level of R&D personnel, R&D personnel management, R&D investment), the dependent variable is R&D efficiency. The moderator is the CEO's competency(experience level in its own industry, technical knowledge level, technology management strategy, management ability). R&D efficiency measures the relationship between inputs(level of R&D personnel, R&D investment) and outputs(patent applications, prototype) by the DEA. and the determinant analysis uses Tobit regression. As a result of the analysis, the existence of R&D organization and R&D personnel management is positively significant, level of R&D personnel and R&D investment is negatively significant for R&D efficiency. The moderating effect of CEO's competency on the relationship between the R&D competency and R&D efficiency is significant determinants of CEO's experience(experience level in its own industry, technical knowledge level) and technology management strategy. The finding is to measure the efficiency of R&D performance, and to analyze its determinants as the moderating effect of CEO's competency, using the technology appraisal data. In the conclusion session, the limitations of the research and future research directions were discussed.

• Journal of Technology Innovation
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• v.23 no.1
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• pp.87-105
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• 2015

This research confirms a non-linear relationship between R&D investment and performance of small and medium-sized enterprises and measures the adequate level as threshold value. Although previous studies did not consider the time lag and estimated indirectly the level using the R&D investment squared term, this study assumes 2 years time lag and uses the threshold estimation model to measure directly. We find that there is the S-curve relationship between the profit rate as R&D output and R&D intensity and the ratio of researchers to employees as R&D input. Also, we estimate the adequate levels of R&D investment, 6.4% for R&D intensity and 13% for the ratio of researchers to employees. This relationship and measurement of the level can offer basic facts and implications about R&D policy and strategy.

• The Korean Journal of Applied Statistics
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• v.29 no.2
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• pp.369-379
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• 2016

The Sigma Level, proposed by Motorola Inc., is one of the many Process Capability Index (PCI)'s that have been presented since the 1970's. It is used to evaluate process capability and unlike other PCI's, it has an advantage in that it uses population probability distribution. However, it is originally designed for mass production and is inadequate to evaluate prototypes or early products in the R&D stages. For use in such cases, we propose an R&D target Sigma Level, derived by considering 1.5 sigma shifts in traditional sigma level from a statistical point of view. We also explain the way to find robust limits for design tolerance because the sigma level or defect probability is useful to establish economical tolerance limits at the R&D stage and mass production.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.24 no.65
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• pp.65-73
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• 2001

In this study, psychophysiological stress was quantitatively evaluated at various car interior noise levels by using Electroencephalogram(EEG). An experiment was performed to investigate the most comfortable range of noise level during simulated driving condition. Twelve healthy volunteers participated in the experiment. They were asked to operate the driving simulator while six levels of interior noise were given, such as 45dB(A), 50dB(A), 55dB(A), 60dB(A), 70dB(A), 80dB(A), and maximal subjective noise level. EEG signals were recorded for 60 seconds in each noise level. The power spectral analysis was performed to analyze EEG signal. At the same time, psychological stress was also measured subjectively by using a magnitude estimation method. The results showed that subjective stress and EEG spectrum indicated a statistically significant difference between noise levels. In particular, high level noise produced an increase in beta power at temporal(T3, T4) areas. It was also found that beta activity was highly correlated with subjective perception of discomfort, and subjects responded to car interior noise as arousing or negative stimuli. Moreover, beta power remained stable above 70dB(A), whereas subjective discomfort continued to increase even above 70dB(A) We concluded that brain waves could provide psychophysiological information of drivers emotional reaction to car interior noise. Thus, EEG parameters could be a new measure to determine optimal noise level in ergonomic workplace design after further verification in various experimental conditions.