• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.42 no.2
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• pp.111-114
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• 2016

The detection of foreign bodies in the upper-aerodigestive tract is a fairly frequent event and can occur in various areas and for various reasons. In rare cases, foreign bodies can simulate a neoplasia. We evaluated similar cases during emergency regimen with an oral cavity mucosal lesion, causing lockjaw, sore throat, dysphagia, and swelling of the submandibular and laterocervical region. Physical examination revealed an extensive mucosal ulceration in the floor of the mouth and the lateral surface of the tongue, comparable to oral cancer. During a second, more accurate assessment, a partially deteriorated iron supplement tablet was found embedded in a mucosal pocket. After removing the tablet, gradual normalization of the tissue was observed without any sequelae. This is one of the many reasons why it is advisable and useful in cases of oral lesions to collect a detailed medical history and to perform an accurate clinical evaluation, including inspection and palpation of the lesion, before proceeding to further diagnostic assessments, especially in elderly patients taking many medications. However unlikely, it is possible that difficulty in swallowing pills or tablets could generate tumorlike lesions.

• The Journal of Korea CHUNA Manual Medicine
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• v.5 no.1
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• pp.19-29
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• 2004

Objectives : Visual check and X-ray are commonly used by chiropractors to estimate ieg length inequality, This study have three categories: diagnosis for anatomic leg length inequality; difference between anatomic and functional leg length inequality; theraphies for anatomic or functional leg length inequality. Methods : We referred to a PubMed site by using word of 'leg length [JU] J Manipulative Physiol Ther', only items with abstracts. Results : We searched 26 articles in J Manipulative Physiol Ther with the key word-Ieg length. Conclusion : 1. Radiographs were most accurate and commonly used by chiropractors to measure anatomic leg length inequality, clinically wood block, tape measure, visual check are acceptable. 2. There was no article about difference between anatomic and functional leg length inequality. 3. Heel lift was commonly used with conservative theraphy for anatomic leg length Inequality. 4. Chiropractors have not yet proved that the supposed positive effects are a result of a reduction of subluxation, The detection of the manipulative lesion in the sacroiliac joint depends on valid and reliable tests, Because such tests have not been established, the presence of the manipulative lesion remains hypothetical. Great effort is needed to develop, establish and enforce valid and reliable test procedures.

• Korean journal of applied entomology
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• v.21 no.1 s.50
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• pp.19-22
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• 1982

There was a highly positive correlation between the number of trapped conidia from fourteen days to four days before direct observation of blast lesion was made and leaf blast incidence. This same relationship was found between the number of conidia trapped from August 11 to August 15 and August 21 to August 25 and percent of panicle blast incidence in a Japonica type cultivar Jinheung. Using iodine-potassium iodide (I-KI) method, it was able to detect infection sites of the blast fungus under the field conditions within 30 minutes. The detection of infection sites was four days earlier than direct observation of leaf blast lesion.

• Korean Journal of Veterinary Research
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• v.33 no.2
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• pp.301-308
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• 1993

Three or 7day old piglets were infected experimentally with different encephalomyocarditis virus isolates to detect the viral antigen by the immunoperoxidase technique and to observe strain difference in their pathogenecity in newborn pigs by comparing clinical signs and pathologic lesions. Clinical signs of the infected pigs were different depending on the virus strain, pig age and infection route. Encephalomyocarditis virus(EMCV) NVSL-PR isolate was more pathogenic than MN-25 and MN-30 isolate. Three day old piglets showed more severe illness than 7 day old piglets. Predominant clinical signs were sudden death without noticeable clinical signs and dyspnea manifested as heavy abdominal breathing. Contact-infection from infected piglets to controls was observed in the oro-nasally infected group but not the intramuscular group. Common necropsy findings of dead piglets in both age groups infected with MN-25 and NVSL-PR were accumulation of excessive fluid in the body cavities and mild to diffuse necrotic areas observed in the hearts and occasionally in the livers. Microscopically, myocarditis with inflammatory cell infiltration, necrosis of the myocardial muscle fibers and occasional mineralization were observed along with interstitial pneumonia and centrolobular necrosis in the liver. Using an immunoperoxidase technique, viral antigen was detected in myocardial muscle fibers of piglets infected with EMCV.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.3
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• pp.678-700
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• 2023

Diagnosing breast diseases using ultrasound (US) images remains challenging because it is time-consuming and requires expert radiologist knowledge. As a result, the diagnostic performance is significantly biased. To assist radiologists in this process, computer-aided diagnosis (CAD) systems have been developed and used in practice. This type of system is used not only to assist radiologists in examining breast ultrasound images (BUS) but also to ensure the effectiveness of the diagnostic process. In this study, we propose a new approach for breast lesion localization and segmentation using a multi-scale pyramid of the ultrasound image of a breast organ and a convolutional semantic segmentation network. Unlike previous studies that used only a deep detection/segmentation neural network on a single breast ultrasound image, we propose to use multiple images generated from an input image at different scales for the localization and segmentation process. By combining the localization/segmentation results obtained from the input image at different scales, the system performance was enhanced compared with that of the previous studies. The experimental results with two public datasets confirmed the effectiveness of the proposed approach by producing superior localization/segmentation results compared with those obtained in previous studies.

• Biomedical Science Letters
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• v.29 no.2
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• pp.53-57
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• 2023

The main objective of pathologists is to achieve accurate lesion diagnoses, which has become increasingly challenging due to the growing number of pathological slides that need to be examined. However, using digital technology has made it easier to complete this task compared to older methods. Digital pathology is a specialized field that manages data from digitized specimen slides, utilizing image processing technology to automate and improve analysis. It aims to enhance the precision, reproducibility, and standardization of pathology-based researches, preclinical, and clinical trials through the sophisticated techniques it employs. The advent of whole slide imaging (WSI) technology is revolutionizing the pathology field by replacing glass slides as the primary method of pathology evaluation. Image processing technology that utilizes WSI is being implemented to automate and enhance analysis. Artificial intelligence (AI) algorithms are being developed to assist pathologic diagnosis and detection and segmentation of specific objects. Application of AI-based digital pathology in biomedical researches is classified into four areas: diagnosis and rapid peer review, quantification, prognosis prediction, and education. AI-based digital pathology can result in a higher accuracy rate for lesion diagnosis than using either a pathologist or AI alone. Combining AI with pathologists can enhance and standardize pathology-based investigations, reducing the time and cost required for pathologists to screen tissue slides for abnormalities. And AI-based digital pathology can identify and quantify structures in tissues. Lastly, it can help predict and monitor disease progression and response to therapy, contributing to personalized medicine.

• Journal of Trauma and Injury
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• v.36 no.3
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• pp.269-275
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• 2023

A Morel-Lavallée lesion results from a degloving injury between the muscle fascia and the subcutaneous layer. It is most commonly found in the trochanteric area but can occur at other sites. The treatment of the condition varies according to the medical circumstances, as well as the size and chronicity of the condition. A case of large (18×6 and 10×5 cm) bilateral posttraumatic Morel-Lavallée lesions with no underlying bone fracture is presented; the case occurred in a 49-year-old male patient 4 weeks posttrauma. Ultrasound scans showed bilateral large collections of anechoic fluid, which were aspirated under ultrasound guidance and further managed by compression bandages. There were no further complications. The objective of this case report is to present this unique and educational case, as well as to provide an overview of the pathophysiology, diagnosis, and management of Morel-Lavallée lesions. We conclude by discussing the importance of having a high index of suspicion to ensure early detection and prompt treatment of such lesions to avoid complications.

• Journal of Biomedical Engineering Research
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• v.40 no.3
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• pp.105-115
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• 2019

Brain tumor surgery may be difficult, but it is also incredibly important. The technological improvements for traditional brain tumor surgeries have always been a focus to improve the precision of surgery and release the potential of the technology in this important area of the body. The need for precision during brain tumor surgery has led to an increase in Robotic-assisted surgeries (RAS). One of the challenges to the widespread acceptance of RAS in the neurosurgery is to recognize invisible tumor accurately. Therefore, it is important to detect brain tumor size and location because surgeon tries to remove as much tumor as possible. In this paper, we proposed brain tumor detection procedures for MRI (Magnetic Resonance Imaging) system. A method of automatic brain tumor detection is needed to accurately target the location of the lesion during brain tumor surgery and to report the location and size of the lesion. In the qualitative assessment, the proposed method showed better results than those obtained with other brain tumor detection methods. Comparisons among all assessment criteria indicated that the proposed method was significantly superior to the threshold method with respect to all assessment criteria. The proposed method was effective for detecting brain tumor.

• Journal of Biomedical Engineering Research
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• v.28 no.1
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• pp.84-94
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• 2007

In order to collect information on local distribution of conductivity and permittivity underneath a scan probe, we developed a multi-frequency trans-admittance scanner (TAS). Applying a sinusoidal voltage with variable frequency on a chosen distal part of a human body, we measure exit currents from 320 grounded electrodes placed on a chosen surface of the subject. The electrodes are packaged inside a small and light scan probe. The system includes one voltage source and 17 digital ammeters. Front-end of each ammeter is a current-to-voltage converter with virtual grounding of a chosen electrode. The rest of the ammeter is a voltmeter performing digital phase-sensitive demodulation. Using resistor loads, we calibrate the system including the scan probe to compensate frequency-dependent variability of current measurements and also inter-channel variability among multiple. We found that SNR of each ammeter is about 85dB and the minimal measurable current is 5nA. Using saline phantoms with objects made from TX-151, we verified the performance of the lesion estimation algorithm. The error rate of the depth estimation was about 19.7%. For the size estimate, the error rate was about 15.3%. The results suggest improvement in lesion estimation algorithm based on multi-frequency trans-admittance data.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.41
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• pp.46.1-46.9
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• 2019

Background: Oral squamous cell carcinoma (OSCC) constitutes a group of tumors that exhibit heterogeneous biology, histopathology, and clinical behaviors. Case presentation: A 73-year-old male had a whitish leukoplakia-like lesion around inflamed peri-implant area (#42, #43, and #44), and this lesion had transformed to OSCC within 3 years. He underwent mass resection, selective neck dissection, and reconstructive surgery. To detect any carcinogenesis progression, we examined the removed tumor tissue as well as the patient's preoperative and postoperative sera to identify causative oncogenic proteins using immunoprecipitation high-performance liquid chromatography (IP-HPLC). Conclusions: The protein expression levels of p53, E-cadherin, β-catenin, MMP-10, HER2, NRAS, Met, HER2, and ERb were significantly lower in the serum collected on postoperative day 10 than in the preoperative serum, and if these proteins are consistently not elevated in the serum 3 months after surgery compared with the preoperative serum, these proteins can be potential oncogenic proteins. However, we also found that the serum extracted 3 months after the operation had elevated levels of oncogenic proteins compared with that of the preoperative and 10-day postoperative serum indicating the possibility of tumor recurrence. At postoperative follow-up period, ipsilateral neck metastasis and second primary lesion were found and additional surgery was performed to the patient. IP-HPLC using the patient's serum shows the possibility of oncogenic protein detection. However, follow-up IP-HPLC data is needed to find out patient-specific prognostic factors.