• 생물정신의학
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• 제12권2호
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• pp.196-206
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• 2005

Objectives:The purpose of this study is to evaluate the pathophysiology of alcoholics by investigating the differences in frequency of Aldehyde Dehydrogenase 2(ALDH2) genotypes and ALDH2 alleles between patients with alcohol dependence and controls, and the differences of drinking and personality traits in Korean male alcoholics with ALDH2 genotype variances. Methods:The authors selected 98 patients with alcohol dependence and 53 controls. Self-report questionnaires for acute reponses after alcohol ingestion, the AUI(Alcohol Use Inventory), and the NEO-PI-R(NEO Personality Inventory Revised) were given to all patients with alcohol dependence. ALDH2 genotypes were typed with MboII RFLP(Restriction Fragment Length Polymorphism) method in 53 controls and 98 patients with alcohol dependence. The authors divided alcoholic patients into two groups according to the presence of variant $ALDH2^2$ allele;normal ALDH2 alcoholics(N=87) and variant ALDH2 alcoholics(N=11). Results:1) The genotypic frequencies of subjects with $ALDH2^{1/1}$ were higher and those with $ALDH2^{1/2}$ and $ALDH2^{2/2}$ were lower in patients than in controls. 2) Alcohol dependence could be found in $ALDH2^{2/2}$ homozygote individuals. 3) Variant ALDH2 alcoholics had more family problems in the AUI than normal ALDH2 alcoholics. 4) Variant ALDH2 alcoholics experienced more flushing and cardiovascular responses after alcohol ingestion than normal ALDH2 alcoholics. 5) Variant ALDH2 alcoholics had less altruistic personality traits in the NEO-PI-R than normal ALDH2 alcoholics. 6) Variant ALDH2 alcoholics tended to have more tolerance to alcohol than normal ALDH2 alcoholics. Conclusion:Variant $ALDH2^2$ allele might play a protective role in the pathogenesis of alcohol dependence and there were several significant differences of drinking and personality traits in Korean male alcoholics with ALDH2 genotype variances.

• 한국세라믹학회지
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• 제53권5호
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• pp.511-520
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• 2016

Electrolyte-supported symmetric Ni-YSZ cermet electrodes of ca. $23{\mu}m$ were prepared by screenprinting and the impedance was measured as a function of humidity from 2% to 90% balanced in $H_2$ at a total flow rate of 50 sccm. The Ni felt current collector of 1 mm thickness exhibited a Gerischer-like gas concentration impedance in the low frequency range, which was similarly observed in the cermet-supported solid oxide cells, while the Pt paste collector exhibited only electrochemical polarization. The electrochemical polarization of both samples was modeled by a non-ideal diffusion-reaction transmission line model including CPEs with ${\alpha}$= 0.5. In the case of the Pt paste collector, all the Bisquert parameters exhibited humidity dependence to the -1/2 power, supporting a non-faradaic chemical reaction mechanism at three phase boundaries. Consequently, the surface diffusivity and reaction rate increased linearly with humidity. Less pronounced humidity dependence and somewhat lower utilization length with an Ni felt collector can be attributed to the diffusion-limited gas flow through the collector.

• 전자공학회논문지D
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• 제35D권4호
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• pp.84-92
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• 1998

A program was developed to analyze the electrical characteristics and harmonic distrotion in a two-dimensional silicon BJT. The finite difference equations of the small signal and its second and thired harmonics for basic semiconductor equations are formulated treating the nonlinearity and time dependence with Volterra series and Taylor series. The soluations for three sets of simultaneous equations were obtained sequantially by a decoupled iteration method and each set was solved by a modified Stone's algorithm. Distortion magins and ac parameters such as input impedance and current gains are calculated with frequency and load resistance as parameters. The distortion margin vs. load resistancecurves show cancellation minima when the pahse of output voltage shifts. It is shown that the distortionof small signal characteristics can be reduced by reducing the base width, increasing the emitter stripe length and reducing the collector epitaxial layer doping concentration in the silicon BJT structure. The simulation program called TRADAP can be used for the design and optimization of transistors and circuits as well as for the calculation of small signal and distortion solutions.

• 한국자기공명학회논문지
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• 제9권1호
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• pp.21-28
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• 2005

$^{11}B$ nuclear magnetic resonance (NMR) measurements have been performed to investigate electronic structures and vortex states of $M_gB_2$ superconductor. The central transition shows a narrow peak down to 25 K at 3.15 T. Below 25 K, an extra line starts to show up and dominates. The extra line is broad and asymmetric with a long tail in the high frequency side, which confirms that this originates from vortex pinning below the irreversibility temperature. From temperature evolution of the fraction and linewidth of the broad portion, temperature dependence of coherence length and penetration depth are extracted.

• Steel and Composite Structures
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• 제37권5호
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• pp.621-632
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• 2020

This research deals with the study of vibrational behavior of armchair and zigzag single-walled carbon nanotubes invoking extended Love shell theory. The effects of different physical and material parameters on the fundamental frequencies are investigated. By using volume fraction for power law index, the fundamental natural frequency spectra for two forms of single-walled carbon nanotubes are calculated. The influence of frequencies against length-to-diameter ratios with varying power law index are investigated in detail for these tubes. To discretize the governing equation in eigen-value form, wave propagation approach is developed. Complex exponential functions have been used and the axial model depends on boundary condition that has been described at the edges of carbon nanotubes to calculate the axial modal dependence. Computer software MATLAB is utilized for the frequencies of single-walled carbon nanotubes and current results shows a good stability with comparison of other studies.

• 지역사회간호학회지
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• 제25권2호
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• pp.75-84
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• 2014

Purpose: This study aimed to identify the level of knowledge on preventing cardiovascular disease (CVD) and nicotine dependency among smoking male college students, and to examine the predicting factors of nicotine dependency. Methods: This study was conducted as cross-sectional descriptive research using structured questionnaires. Data were collected from 411 smoking male college students ($22.5{\pm}2.59$ yr) at two universities located in two cities in Korea from September 2012 to April 2013. Logistic regression analysis was performed to estimate age-adjusted odds ratios of nicotine dependency. Results: The mean value of nicotine dependency was $4.2{\pm}1.96$ and the percentage of participants who had strong nicotine dependency (${\geq}7$) was 10.7%. Logistic regression analysis showed that, when adjustment was made for age, nicotine dependency was predicted by the frequency of alcohol drinking (${\geq}3$ times/week), knowledge on CVD prevention, the age starting drinking, and the total length of smoking. Conclusion: Nicotine dependency was strongly related to the frequency of drinking alcohol and lower knowledge on CVD prevention. Therefore, male college students who have a dependent smoking habit and drink alcohol frequently need to take more interest in health through educational counseling to modify their lifestyle behaviors and to have preventive knowledge related to CVD.

• Mass Spectrometry Letters
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• 제10권2호
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• pp.50-55
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• 2019

The fragmentation statistics of ion trap CID (Collision-Induced Dissociation) spectra using 87,661 tandem mass spectra of doubly charged tryptic peptides are analyzed here. In contrast to the usual method of using intensity information, the frequency of occurrence of fragment ions, with respect to the position of the cleavage site and the residues at these sites is studied in this paper. The analysis shows that the frequency of occurrence of fragment ion peaks is more towards the middle of the peptide than its ends. It was noted that amino acid with an aromatic and basic side chain at N- & C- terminal end of the peptide stimulates more peaks at the lower end of the spectrum. The residue pair effect was shown when the amide bond occurs between acidic and basic residues. The fragmentation at these sites (D/E-H/R/K) stimulates the generation of the y-ion peak. Also, the cleavage site H-H/R/K stimulates the generation of b-ions. K-P environment in the peptide sequence has more tendency to generate y-ions than b-ions. Statistical analysis helps in the visualization of the CID fragmentation pattern. Cleavage pattern along the length of the peptide and the residue pair effects, enhance the knowledge of fragmentation behavior, which is useful for the better interpretation of tandem mass spectra.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2014년도 전력전자학술대회 논문집
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• pp.237-238
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• 2014

A studies about HID resonanse ignition circuit. it need more than 2kV of the output voltage. then the breakdown voltage of the output capacitor must be higher, size of the capacitor must be larger, and price are higher. so were studied possible ways by resonating by distributing the secondary number of turns of the transformer, it would reduce the breakdown voltage of the output capacitor. we also studied the method can be lit at long distance, to control the resonance frequency in dependence on its parasitic capacitor that vary according to the length of the wire.

• 한국문헌정보학회지
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• 제45권4호
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• pp.209-234
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• 2011

본 연구는 공공도서관 이용자를 대상으로 장소애착도와 장소가치인식도 간의 영향관계를 통계적으로 검증해보고, 이용빈도, 거주기간, 이용목적, 웹사이트 이용경험이 장소애착도와 장소가치인식도 간의 관계에서 조절변수로서의 역할을 하는지 파악하고자 했다. 계층적 회귀분석결과, 이용빈도와 거주기간이 '장소의존성'과 상호작용하여 '체험가치인식도'에 정(+)의 영향을 미치는 것으로 나타났다. 이용목적에 대한 조절효과를 알아보기 위해 이용목적별로 집단을 구분하고 장소애착도와 장소가치인식도와의 관계를 집단별로 분석하였다. 도서관 웹사이트 이용경험은 장소애착도와 장소가치인식도와의 관계에서 조절효과를 보이지 않았다. 본 연구 결과는 장소애착도라는 이용자의 감정적인 지표가 장소로서의 공공도서관의 가치를 설명할 수 있는 변수로서 활용성이 있음을 시사하고 있다.

• Journal of Astronomy and Space Sciences
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• 제19권4호
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• pp.243-254
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• 2002

Sondrestrom 비간섭 산란 레이더로부터 구한 전자밀도분포를 이용하여, 전리층의 전기전도도를 추정할때 야기되는 불확실성들을 검토하였다. 첫째, 실제로 관측된 전자밀도와 전자와 양이온의 온도차이 및 Debye length효과를 보정한 전자밀도를 사용했을 경우에 야기되는 전리층 전기전도도의 차이점을 비교하였다. 보정한 전자밀도로부터 추정된 전기전도도는 실측 전자밀도를 사용했을 때 보다 큰 값을 나타내었다. 둘째, 전기전도도 추정에 이용되는 전자-중성대기 및 양이 온-중성대기의 충돌빈도모델에 따른 차이점도 비교해 보았다. 약 110km 이하의 고도에서는 전기전도도가 충돌빈도모델에 크게 의존하지 않았지만, 약 110km 이상의 고도에서는 이용된 모델에 따라 전기전도도의 값이 달랐다. 셋째, 전자 및 양이온의 부정확한 온도측정이 전기전도도의 추정에 미치는 영향을 알아보았다. 전자 및 양이온의 온도측정에 약 10% 이내의 오차가 포함된 경우가 전기전도도의 계산에는 큰 영향을 미치지 않았다. 마지막으로, 고도 적분된 전기전도도의 추정시 적용되는 적분 구간에 대해서도 검토해 본 결과, Hall 및 Pedersen 전기전도도의 값이 각각 하부 및 상부 적분 고도의 선택에 매우 민감하다는 것이 밝혀졌다.