• 대한두경부종양학회지
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• 제35권2호
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• pp.31-34
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• 2019

Lemierre's syndrome is rare disease characterized by anaerobic sepsis, internal jugular vein thrombosis, septic emboli that resulted from head and neck infection. Lemierre's syndrome has significant morbidity, so immediate, accurate diagnosis and treatment is needed. It is necessary to perform contrast-enhanced computed tomography (CT) for diagnosis. Systemic antibiotics is recommended, and surgical interventions, anticoagulation may beis considered for treatment. We report misdiagnosed case as a simple deep neck infection on initial ultrasonography with simultaneous abscess aspiration but finally diagnosed and treated internal jugular vein thrombophlebitis (Lemierre's syndrome) on CT scan. We report a case of a 45-year-old patient, who was diagnosed with a simple deep neck infection and treated with simultaneous abscess aspiration, but finally diagnosed and treated internal jugular vein thrombophlebitis (Lemierre's syndrome) on CT scan.

• Pediatric Infection and Vaccine
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• 제23권2호
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• pp.143-148
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• 2016

Lemierre 증후군은 급성 입인두 감염의 합병증으로 생기는 질환으로, 이차적인 혈전 정맥염과 여러 장기를 침범하는 전이성 색전이 특징이다. 1940년대 이후 항생제가 도입되면서 "잊혀진" 질환이었지만, 영상의학 검사가 발달하면서 Lemierre 증후군의 보고가 많아지고 있다. 건강한 16세 남자 환자가 입인두 감염 후에 5일간 지속된 발열과 경부 강직으로 응급실에 내원하였다. 입원 초기에는 뇌수막염에 준하여 치료를 시작하였으나 추후 경부 전산화 단층촬영에서 오른쪽 속목정맥 안의 혈전이 발견되어 Lemierre 증후군으로 진단하였다. 환자는 입원 2일째 갑자기 복시를 호소하였으나 곧 증상이 호전되었으며, 그 외 전이성 색전에 의한 증상은 발견되지 않았다. 총 3주간의 항생제 치료 후 정맥 내 혈전이 소실된 것을 경부 초음파로 확인하고 치료를 종료하였다.

• 대한기관식도과학회지
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• 제16권2호
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• pp.149-153
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• 2010

Lemierre syndrome, also known as postanginal sepsis, is a severe complication of an acute oropharyngeal infection that result in septic thrombophlebitis of the internal jugular vein with subsequent septicemia. This disease is relatively rare, but it has significant morbidity and is potentially fatal. Early diagnosis based on computed tomography with contrast enhancement is mandatory and immediate treatment including intravenous antibiotics, anticoagulants, or surgical approach should be considered. We report a case of Lemierre syndrome after deep neck infection which was successfully treated using antibiotics and anticoagulants.

• Journal of Chest Surgery
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• 제34권8호
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• pp.644-647
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• 2001

Lemierre 증후군은 원발성 구인두 감염증으로 인하여 내경정맥의 패혈성 혈전정맥염과 원격전이성 감염증이 발생하는 드물고도 진행이 빠른 임상적 상태로 특징지워진다. 심한 흉부 외상으로 기관 절개하에서 기계호흡 치료 중이던 40세 남자 환자가 우측 경부의 현저한 종창과 폐렴증상이 나타나면서 전신적인 패혈증상이 동반되었다. 경부 전산화 단층촬영과 자기공명 혈관조영술에서 우측 내경정맥이 큰 중심 괴사성 혈전에 의해 완전히 폐쇄되어 있었으며, 주위로의 염증파급이 매우 심한 혈전정맥염의 소견을 보였다. Clindamycin과 haparin의 투여에도 불구하고 염증소견은 더욱 악화되었다. 즉각적인 내경정맥 혈전제거술 및 절제술을 시행하였으며, 이후 환자의 전신적인 패혈증상과 폐렴 그리고 국소적인 염증소견이 소실되었다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제21권3호
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• pp.214-217
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• 2018

Inflammatory bowel disease (IBD) is a well-recognized risk factor for thrombotic events in adults but data on children are scarce. In the great majority of adult patients, thrombotic events are usually deep vein thrombosis and pulmonary embolism. Other sites such as jugular veins are extremely rare. We present a case of Lemierre syndrome in an adolescent girl with active ulcerative colitis and discuss possible risk factors. This is the first reported case of severe Lemierre syndrome with thrombus extension to cranial veins in a patient with ulcerative colitis. Early recognition of Lemierre syndrome in patients who present with rapidly worsening symptoms of neck pain, fever and signs of pharyngitis is imperative because it increases a chance of favorable prognosis. It is important for pediatricians treating IBD patients not to underestimate possible thrombotic events in children with IBD. Recognition of additional risk factors is crucial for prompt diagnosis and adequate treatment.

• Tuberculosis and Respiratory Diseases
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• 제78권3호
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• pp.289-292
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• 2015

Lemierre syndrome (LS) is a septic thrombophlebitis of the internal jugular vein (IJV) following an oropharyngeal infection. LS is commonly caused by normal anaerobic flora and treated with appropriate antibiotics and anticoagulation therapy. Although the incidence of disease is very rare, 15% cases of LS are fatal even in the antibiotic era because of disseminated septic thromboemboli. We reported a case of extensive bilateral LS due to methicillin-resistant Staphylococcus epidermidis in a 63-year-old female with lung adenocarcinoma. Initial examination revealed a retropharyngeal abscess; hence, intravenous ceftriaxone and steroid were initiated empirically. However, pulmonary thromboembolism developed and methicillin-resistant S. epidermidis was identified in the bacterial culture. Despite intensive antibiotic and anticoagulation therapies, extensive septic thrombophlebitis involving the bilateral IJV and superior vena cava developed. Adjunctive catheter-directed thrombolysis and superior vena cava stenting were performed and the patient received antibiotic therapy for an additional 4 weeks, resulting in complete recovery.

• Journal of Korean Dental Science
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• 제5권2호
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• pp.88-92
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• 2012

Also called necrobacillosis or postanginal sepsis, Lemierre's syndrome (LS) is an uncommon but potentially lethal complication of odontogenic infection. A 27-year-old male diagnosed with Ludwig's angina was transferred from a local hospital due to continuous fever and chills after incision and drainage under general anesthesia. The swelling of both submental and submandibular area subsided, but the fever and chills persisted. While generalized malaise improved, sepsis developed together with the deterioration of liver function. The chest computed tomography scan revealed multiple cavitations throughout both lungs, which were diagnosed as septic pulmonary embolism. After consulting the department of infectious diseases, the patient was treated with intravenous antibiotics focusing on vancomycin and additional antibiotics. After 3 weeks of treatment, the patient recovered completely. Despite its decreased mortality, dentists are not familiar with LS, and it is difficult to diagnose correctly. In this paper, we report a case and present a review of literature.