• Title/Summary/Keyword: Leishmanis tropica

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Successful Treatment of Lupoid Cutaneous Leishmaniasis with Glucantime and Topical Trichloroacetic Acid (A Case Report)

  • Nilforoushzadeh, Mohamad Ali;Sadeghian, Giti;Jaffary, Fariba;Ziaei, Hengameh;Shirani-Bidabad, Liela;Mahzoni, Parvin
    • Parasites, Hosts and Diseases
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    • v.46 no.3
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    • pp.175-177
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    • 2008
  • Lupoid leishmaniasis is a unique form of cutaneous leishmaniasis characterized by unusual clinical features and a chronic relapsing course, mostly caused by infection with Leishmania tropica. In this clinical form, 1-2 yr after healing of the acute lesion, new papules and nodules appear at the margin of the remaining scar. Herein, we describe a case of this clinical form that was resistant to 2 courses of treatments: systemic glucantime and then a combination therapy with allopurinol and systemic glucantime. However, marked improvement was seen after a combination therapy with topical trichloroacetic acid solution (50%) and systemic glucantime, and there were no signs of recurrence after 1 yr of follow-up.