• Title/Summary/Keyword: Lee Sam

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Measurement and Analysis of the Dynamics of Peptide-Antibody Interactions Using an Ellipsometric Biosensor Based on a Silicon Substrate (실리콘 기판을 사용한 바이오센서와 회전 타원분광계를 이용한 펩타이드-항체 접합의 동특성 측정과 분석)

  • Lee, Geun-Jae;Cho, Hyun Mo;Jo, Jae Heung
    • Korean Journal of Optics and Photonics
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    • v.28 no.1
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    • pp.9-15
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    • 2017

  • We precisely measured and analyzed the dynamics of peptide-antibody interactions, using an ellipsometric biosensor based on a silicon substrate. To reduce the signal error due to the imperfect flatness of the substrate for extremely low concentrations of peptide, we fabricated the biosensor with a silicon substrate coated with Dextran SAM, instead of a glass prism coated with a thin metallic thin film. At an injection speed of $100{\mu}l/min$ of buffer liquid, we detected the dynamics of antibody-Dextran SAM or peptide-antibody fixed on biosensor, respectively. We detected the dynamics of antibody-Dextran SAM interactions down to a low concentration of 5 ng per liter, and we precisely measured the dynamics of association and dissociation of peptide and antibody down to 100 nM of peptide. We obtained the rate constants for association and dissociation from fitting the data by using deduced dynamical equation. As a result, we obtained an equilibrium constant for dissociation of 97 nM of peptide-antibody complex, which belongs to Class I.

  • https://doi.org/10.3807/KJOP.2017.28.1.009 인용 PDF KSCI

Changes in Growth and Nutrient Contents of Populus ablba var. pyramidalis treated with Fertilizers and Absorbents in an Arid Region of China (중국 건조지역에서 시비와 보수제 처리에 의한 신강포플러의 생장 및 묘목의 양분 함량 변화)

  • Kyung, Ji Hyun;Son, Yohwan;Noh, Nam Jin;Yi, Myong Jong;Lee, Chun Yong;Youn, Ho Joong
    • Journal of Korean Society of Forest Science
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    • v.95 no.6
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    • pp.751-758
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    • 2006

  • To investigate soil management practices for increasing tree growth in arid regions of China, Xinjiang poplar (Populus alba var. pyramidalis) seedlings were planted in a nursery and windbreak and were treated with fertilizers (nitrogen and phosphorus) and absorbents (artificial; K-SAM and natural: Yuho (Artemisia ordosica)) at Dengkou in Inner Mongolia. Seedling height, diameter at breast height (DBH), biomass, and nitrogen (N) and phosphorus (P) concentrations were measured 1.5 years after the treatments. Soil texture was sandy loam for nursery and clay loam for windbreak, soil pH was 8.78 for nursery and 8.51 for windbreak, and total soil N concentration was 0.06% for nursey and 0.08% for windbreak. [n general, seedling height and DBH increased in the N fertilizer treatment compared to control or other treatments both in nursery and windbreak. Also seedling growth increased after the treatments of artificial and natural absorbents in windbreak. Total above- and belowground biomass increased after the N + P treatment. Foliage N and P concentrations following N and/or P treatments were same in the nursey, however, they significantly increased in the windbreak indicating N deficiency. It appeared that N was a limiting factor for early growth of Xinjiang poplar seedlings and artificial and natural absorbents (K-SAM and Yuho) would be useful to increase seedling growth in the arid region.

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Tuning Electrical Performances of Organic Charge Modulated Field-Effect Transistors Using Semiconductor/Dielectric Interfacial Controls (유기반도체와 절연체 계면제어를 통한 유기전하변조 트랜지스터의 전기적 특성 향상 연구)

  • Park, Eunyoung;Oh, Seungtaek;Lee, Hwa Sung
    • Journal of Adhesion and Interface
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    • v.23 no.2
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    • pp.53-58
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    • 2022

  • Here, the surface characteristics of the dielectric were controlled by introducing the self-assembled monolayers (SAMs) as the intermediate layers on the surface of the AlOx dielectric, and the electrical performances of the organic charge modulated transistor (OCMFET) were significantly improved. The organic intermediate layer was applied to control the surface energy of the AlOx gate dielectric acting as a capacitor plate between the control gate (CG) and the floating gate (FG). By applying the intermediate layers on the gate dielectric surface, and the field-effect mobility (μOCMFET) of the OCMFET devices could be efficiently controlled. We used the four kinds of SAM materials, octadecylphosphonic acid (ODPA), butylphosphonic acid (BPA), (3-bromopropyl)phosphonic acid (BPPA), and (3-aminopropyl)phosphonic acid (APPA), and each μOCMFET was measured at 0.73, 0.41, 0.34, and 0.15 cm2V-1s-1, respectively. The results could be suggested that the characteristics of each organic SAM intermediate layer, such as the length of the alkyl chain and the type of functionalized end-group, can control the electrical performances of OCMFET devices and be supported to find the optimized fabrication conditions, as an efficient sensing platform device.

  • https://doi.org/10.17702/jai.2022.23.2.53 인용 PDF KSCI