• Title/Summary/Keyword: Lee Sam

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A Clinical Study on Polycythemia Vera (진성다혈증(眞性多血症)에 관(關)한 임상적고찰(臨床的考察))

  • Lee, Gwon-Jun;Hong, Kee-Suck;Cho, Kyung-Sam;Kim, Byoung-Kook;Kim, Noe-Kyeong;Koh, Chang-Soon;Lee, Mun-Ho
    • The Korean Journal of Nuclear Medicine
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    • v.11 no.1
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    • pp.59-70
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    • 1977
  • Eight patients with polycythemia vera were diagnosed from 1965 through 1977 among the patients of Seoul National University Hospital. In our series there were 4 men and 4 women with average age of 54 years at the time of diagnosis. Symptoms of facial plethora, headache, pruritus and dizziness were the most frequent manifestations of disease in order of frequency. At inital examination 8 of 8 patients had facial plethora, 6 of 8 patients splenomegaly and 4 if 8 patients hepatomegaly. The laboratory data revealed mean Red cell volume of 55+10ml/kg which was elevated in all cases. Leukocytosis was observed in 5 of 8 patients and thrombocytosis 2 of 8 patients. Leukocyte alkaline phosphatase was increased in all cases. Bone marrow aspiration disclosed typical panmyelosis in 5 of 8 patients. In one patient there was diffuse myelofibrosis on bone marrow biopsy. The combined diseases included 2 patient with hypertension and 1 patient with thrombosis of aorta and left renal artery. The patients were treated with phlebotomy alone in 2 patients, chemotherapy with busulfan in 1 patient and $^{32}P$ in 5 patients with favorable results. During the mean 29.9 months follow up period, there were development of iron deficiency in 3 patients, hyperuricemia in 2 patients and thrombosis in 1 patient. The occurrence of acute leukemia of myelofibrosis was not observed in the course of disease.

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Protein Partition in an Aqueous Poly (ethyleneglycol)-salt Two-phase System (Poly(ethyleneglycol)과 인산염용액이 형성하는 2상계에서의 단백질 분획에 관한 연구)

  • Lee, Sam-Pin;Lee, Cherl-Ho
    • Korean Journal of Food Science and Technology
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    • v.19 no.4
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    • pp.285-289
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    • 1987
  • The partition behavior or proteins in an aqueous two-phase system of poly (ethyleneglycol)-potassium phosphate buffer (PEG/PPB) was investigated. The proteins of different surface hydrophobicity, i.e. Bovine serum albumin (BSA), ${\beta}-lactoglobulin$, ovalbumin. moved to the PPB-rich bottom phase in a PEG(12%)/PPB (12%) two-phase system resulting in very low partition coefficients. When the concentration of PPB increased to 15% level. the electric potential of bottom phase changed from +50 mV to zero and the partition coefficient tended to increase. The change In the molar ratio of $K_2HPO_4/KH_2PO_4$ in PPB from 1.43 to 9.55 caused the volume ratio of top to bottom phase $(V_t/V_b)$ to be decreased and protein partition coefficient increased. When the concentration of PPB was elevated from 14% to 26%, the $V_t/V_b$ decreased from 1.5 to 0.39 and the partition coefficient of proteins increased drastically; ${\beta}-lactoglobulin$ 74 fold. BSA 32 fold, ovalbumin 12 fold and lysozyme 5 fold.

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Study on the Mechanical Properties of Mo Series High Speed Tool Steel Austempered (Mo계 고속도 공구강의 오스템퍼렁에 따른 기계적 성질에 관한 연구)

  • Choi, M.S.;Lee, H.W.;Rho, Y.S.;Kim, Y.H.;Kim, H.G.;Lee, S.Y.
    • Journal of the Korean Society for Heat Treatment
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    • v.4 no.1
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    • pp.1-12
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    • 1991
  • This study has been performed to find out the effect of austenitizing temperature, austempering temperature and its holding time, and tempering cycle on the mechanical properties such as impact resistance, hardness etc. of AISI $M_2$ Mo series high speed tool steel austempered or tempered after austempering treatment. The results obtained from the experiment are as follows ; (1) Optical micrograph has revealed that the transformation rate of bainite is delayed as the austenitizing temperature increases and that bainite is most apparently transformed at an austempering temperature of $290^{\circ}C$. (2) The amount of retained austenite during austempering has been analysed to be increased by the X-ray diffraction technique as the transformation product of bainite is increased. It has also been shown that the longer the holding time of austempering, the more the transformation quantity of bainite is formed, exhibiting, however, that the rate of bainitic transformation is considerably retarded after a certain period of holding time elapses. (3) Hardness measurement has shown that hardness values obtained after austempering increase with decreasing the amount of retained austenite. (4) The austempering and then tempering cycle has been formed to give hardness values which are more greatly improved as austenitizing temperature is increased. (5) The mechanical property of the specimen primary-tempered for 1 hour at $550^{\circ}C$ after austempering for 2 hours at $290^{\circ}C$ from the austenitizing temperature range of $1180^{\circ}C$ to $1210^{\circ}C$ have been estimated to be good values.

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Effect of Pallet-unit MAP Treatment on Freshness Extension of Spring Chinese Cabbage (Pallet-unit MAP처리에 따른 봄배추의 선도 연장 효과)

  • Lee, Young-Joo;Lee, Hye-Ok;Kim, Ji-Young;Kim, Byeong-Sam
    • Journal of the Korean Society of Food Culture
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    • v.31 no.6
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    • pp.634-642
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    • 2016
  • Chinese cabbage is produced and consumed as a main material for kimchi and as a staple vegetable in Korea throughout the year. However, due to environmental changes unbalance between supply and demand is repeated annually, requiring development of long-term storage technologies. Chinese cabbages, were harvested, put in plastic boxes, and precooled at $2^{\circ}C$ for 24 hours using forced air precooler. After precooling, Chinese cabbages were MAP-treated with 0.02 mm HDPE film and functional film and stored at low temperature ($1{\pm}0.5^{\circ}C$). The weight-loss rates after 9-weeks of storage were 8.47% in the control group, 4.07% in the HDPE film-treated group, and 3.07% in the functional film-treated group, respectively, suppressing weight loss. Trimming loss rate after 6-weeks of storage was 6.86% in the functional film MAP-treated group and lower than 7.50% in the control group. In the sensory test with 7 points as the limit of commodity, the control group lost it after 6-weeks of storage while the MAP-treated groups retained over 7 points. The functional film MAP-treated group showed over 6 points for processing as kimchi until 9-weeks of storage, proving that Pallet-type MAP storage is effective for extending storage life of spring Chinese cabbage.

Pineal Germinoma Associated with Chronic Granulomatous Inflammation - Case Report - (육아종성 염증을 동반한 송과체 배아종 - 증례보고 -)

  • Moon, Kyung Sub;Jung, Shin;Kang, Sam Suk;Kim, In Young;Kim, Hyun Woo;Lee, Jung Kil;Kim, Tae Sun;Kim, Jae Hyoo;Kim, Soo Han;Lee, Je Hyuk
    • Journal of Korean Neurosurgical Society
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    • v.30 no.sup1
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    • pp.170-173
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    • 2001
  • Germinoma associated with chronic granulomatous inflammation of pineal gland has been rarely reported in the literature. The mechanism of chronic granulomatous inflammation is not understood well. We report a case of chronic granulomatous inflammation in pineal germinoma. In a 17 year-old male who suffered from headache and diplopia for six months, the mass of pineal gland was detected by brain MRI and removed through occipital transtentorial approach. The pathological specimen revealed the mass was predominantly composed of chronic granulomatous inflammation associated with small portion of germ cell tumor nests In the pathological interpretation of chronic granulomatous inflammation of pineal mass, it would be obliged to search for the presence of germ cell component.

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Seamless handover protocol to reduce handover latency (핸드오버 지연 시간을 줄일 수 있는 심리스 핸드오버 프로토콜 제안 및 성능 분석)

  • Jang, Jong-Min;Lee, Yu-Tae;Lee, Soong-Hee;Kim, Dong-Il;Choi, Sam-Gil
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.2
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    • pp.277-284
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    • 2009
  • With significant development in wireless communication technologies, the needs to handover from one network to another have grown dramatically. Recently IETF developed MIPv6 and FMIPv6 which are used to handover between different access networks. These handover mechanisms have some known weaknesses. MIPv6 can not serve time-critical application because it causes long handover latency and packet loss. By these reasons, MIPv6 does not guarantee session continuity. FMIPv6 uses handover preparation phase to reduce DAD latency. However FMIPv66 still suffers from long handover latency, because it must perform binding update at the end of handover procedure. In this paper we propose new handover mechanism FMIPv6-PBU which eliminates binding update latency. The proposed mechanism has compatability with lagacy FMIPv6. In this paper propose FMIPv6-PBU handover procedure and explain its procedures and evaluate it with MIPv6 and FMIPv6.

Two Year Experiences of the International Elective Clerkship for Medical Students (2년간의 의과대학 학생의 해외임상실습 경험)

  • Lee, Sam-Beum;Bang, Jae-Beum;Lee, Young-Hwan
    • Journal of Yeungnam Medical Science
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    • v.26 no.1
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    • pp.24-29
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    • 2009
  • Background : The aims of medical education have recently been changing in Korea, which has been accompanied by efforts to modify the rotating clerkship courses, improve the quality of clinical education, and make global doctors. We report the experiences of medical students going through an international elective clerkship for during past two years. Materials and Methods: Third year medical students could apply to the international elective clerkship course during a 4 week period alter their third-year rotating clerkship at a university hospital. This was done twice - in 2008 and in 2009. Applicant students were allowed to select hospitals anywhere in the world. We analyzed their choices including data on nation, state or city, hospital or institute, contacted hospitals by medical college, differences of two years, etc. Results : Twelve students (10.9%) of a total of 75 third-year students applied to 3 nations and 4 hospitals in 2008. Nine students applied to the Tampa General Hospital at the University of South Florida (USF) in the USA, which was arranged by their medical college. In 2009, a total of five (4.2%) of 77 students applied to 2 nations and 3 hospitals, including three at the University of South Florida, one in another city in the USA, and one in another nation because of the increased financial burden due to a higher exchange rate. Conclusion: Medical students started their first international elective clerkship courses during the past two years. Experiences were interesting and meaningful to the students and the medical college. Greater effort and support to developing a new paradigm and to enlarge the scope of the program for making global doctors are required in the future.

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InAs 양자점의 AlxGax-1As 장벽층 구조에 따른 광학적 특성

  • Han, Im-Sik;Lee, Sang-Jo;Jo, Hyeon-Jun;Bae, In-Ho;Kim, Jong-Su;Kim, Yeong-Ho;Kim, Seong-Jun;Kim, Jun-O;Lee, Sang-Jun;No, Sam-Gyu;Park, Dong-U;Kim, Jin-Su
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.08a
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    • pp.235-235
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    • 2010
  • 본 연구에서는 태양전지의 활성영역에 삽입할 InAs 양자점에 AlxGax-1As 장벽층을 삽입하여 그 두께변화에 따른 광학적 특성 변화를 photoreflectance spectroscopy (PR)과 photoluminescence (PL)를 이용하여 연구하였다. 본 연구에 사용된 InAs/AlGaAs 양자점 구조는 GaAs (100) 기판 위에 GaAs buffer layer를 500 nm 성장 ($Ts=580^{\circ}C$) 후 기판온도 $470^{\circ}C$에서 InAs 양자점, GaAs cap 층과 AlxGax-1As 장벽층 순서로 5 층의 InAs/GaAs/AlxGax-1As 양자점 구조를 형성하였다. GaAs cap 층의 두께는 4 nm로 고정하고 AlGaAs 장벽층 두께를 0~6 nm 까지 변화시켰다. 각 양자점 층 사이에 AlxGax-1As 장벽층의 삽입 유무에 따라 PR 신호에서 Franz-Keldysh oscillation (FKO)의 주기 변화가 관측되었다. AlGaAs 두께가 증가 할수록 PL 신호의 세기가 증가함을 보였으며 PL 신호의 온도의존 특성이 변화됨을 관측할 수 있었다. AlGaAs 장벽층 대신 AlAs 장벽층을 삽입한 시료에서도 유사한 경향성을 관측하였으며, 이는 양자점에 구속된 운반자의 터널링 현상과 높은 장벽층에 의한 운반자의 구속 강도의 변화에 의한 것으로 사료된다. 특히 장벽층의 유무에 따른 FKO의 변화는 시료의 표면 전기장의 변화에 기인한 것으로 운반자의 구속효과뿐만 아니라 InAs 양자점 성장중 형성된 표면결함 밀도의 변화에 의한 것으로 추정하였다.

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Variation Characteristic of Wave Field around 2-Dimensional Low-Crested-Breakwaters (2차원저천단구조물(LCS)의 주변에서 파동장의 변동특성)

  • Lee, Jun Hyeong;Jung, Uk Jin;Bae, Ju-Hyun;Lee, Kwang-Ho;Kim, Do-Sam
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.31 no.5
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    • pp.294-304
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    • 2019
  • This study evaluates the variation characteristics of wave fields (transmission ratio, wave height, time-averaged velocity and time-averaged turbulent kinetic energy) for two-dimensional low-crested structure by olaFlow model based on the two-phases flow numerically. In addition, the present numerical results are verified by comparing with the existing experimental results. The time-averaged velocity, one of various numerical results is formed counterclockwise circulating cell on the front of structure and is occurred strong uni-directional flow on onshore side. It is shown that these are closely related to the factors such as overtopping, etc.

Hepatoprotective Activities of Glycyrrhizin and Baicalin in Primary Cultured Rat Hepatocytes (흰쥐의 일차배양 간세포에서 Glycyrrhizin 및 Baicalin의 간 보호 활성 평가)

  • Kim, Sung-Hwa;Cheon, Ho-Jun;Park, Jin-Gu;Kim, Yeong-Sik;Kang, Sam-Sik;Xu, Guang-Hua;Lee, Seung-Ho;Son, Kun-Ho;Lee, Sun-Mi
    • YAKHAK HOEJI
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    • v.50 no.6
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    • pp.358-366
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    • 2006
  • The aim of this study was to investigate the protective effects of glycynhizin, active glycosides of Glycyrrhizae Radix, and baicalin, bioactive flavonoid isolated from Scutellariae Radix, on hepatocyte injury induced by carbon tetrachloride(CCl$_4$, 10 mM), tert-butyl hydroperoxide (TBH, 0.5 mM), and D-galactosamine (GaIN, 30 mM). Primary cultures of rat hepatocyte (18 hr cultured) were treated with CCl$_4$, TBH, or GaIN and various concentrations (0.1, 1, 10, and 100 ${\mu}$M) of glycyrrhizin or baicalin. Activity was accessed by determining the release of lactate dehydrogenase (LDH) and aminotransferses. CCl$_4$ significantly increased the levels of LDH, alanine aminotransferase (ALT), and aspartate aminotransferase(AST) and these increases were prevented by baicalin concentrations of 0.1,1, and 100 ${\mu}$M. The increases in ALT and AST levels were reduced by glycyrrhizin concentration of 100 ${\mu}$M. The level of LDH was markedly increased by TBH, and this increase was reduced by both glycyrrhizin and baicalin. ALT and AST levels were increased by TBH, which were prevented by glycynhizin and bacalin, respectively: GaIN markedly increased the levels of LDH, ALT and AST These increases was significantly reduced by both glycyrrhizin and baicalin. These results suggest that glycynhizin and baicalin possess the hepatoprotective activity.