• Archives of Pharmacal Research
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• v.12 no.4
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• pp.249-253
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• 1989

High producers or blocked mutants of aminoglycoside antibiotic-producing Streptomyces spp. were selected by application of an agar plug method and by culturing individual colonies in broth. The productivities of aminoglycoside antibiotic producing organisms were increased by selection of a high producer from colonies obtained by spreading spores of wild strain, or survived from treatment of a mutagen or from the colonies regenerated from protoplast-formation and cell-wall regenerations. Some mutagen treated colonies lost the ability to produce antibiotics (5-8%). Some A-factor negative and deostreptamine or streptidine negative mutants were obtained by N-methyl-N'-nitro-N-nitrosomethylguanidine (MNNG) treatment. Many of the survivors from the MNNG treatment lost the ability to produce antibiotics. Major colonies produced less amount of antibiotics ; only few survived colonies produced more antibiotics than the parent. Resistance of Streptomyces spp. against the antibiotics produced by itself was also markedly affected by mutagen treatment.

• Journal of the Korean Society for Railway
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• v.12 no.6
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• pp.865-872
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• 2009

Korean railroad company is continuously improving the service for the disabled. They also install and reform many facilities for them. However, It is not considered the importance of egress when fire occurred in a cabin Now, Fire hazard analysis and risk assessment are introduced into domestic regulations for improving fire safety performance of train car and railroad facilities. Considering the fact that fire safety evaluation process doesn't fully include disabled person, fundamental egress data for them is very important for life safety aspect. In this paper, Egress experiments and analysis were conducted to measure the movement speed of the disabled with Mugunghwa and Saemaul.

• Journal of Fisheries and Marine Sciences Education
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• v.17 no.1
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• pp.86-105
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• 2005

The plan of developing a fishing village and port will be indirectly funded by the government. In the short term, there will be five different multi-functional fishing village models which are based on the first industry to attach to the third industry of marine sports experience tourism. In the long run, they have to be reached gradually. The popular scenic spot of the marine sports experience tourism is made by human resources and fundamental installations considering that it must be done in unpolluted water. It is necessary to separate the fish harbor into two sides. One side is an existing fishing industry. The other side is made up of several pontoons for the marine sports equipment of the marine mooring. It is necessary to build facilities, such as the mooring facility, the storage facility, the repair-check facility, supply-cleaning facility, information booth, accommodations, education facility, and a marine culture exchange facility.

• Journal of radiological science and technology
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• v.22 no.2
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• pp.23-26
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• 1999

The Zygomatic arch is structurally protruded and is easily fractured. The classic management of zygomatic arch fracture has been mentioned the Keen, Lothrop, Dingman and Ailing and threaded K-wire. All of the above methods have advantages and disadvantages. To minimize the disadvantages, we performed threaded K-wire for the first time using C-arm image intensifier. The subjects were 16 patients with Knight North group II (Zygomatic arch fracture). Among them the C-arm was used in 12 patients and the operator used sensitivity general method in 4 patients and confirmed the operation by mobile X-ray equipment. In conclusion, both groups were satisfied surgically and cosmetically. Using the C-arm, actual image at the time operation was clear and satisfied, the surrounding tissue damage was minimized and at was more accurately completed. The operation time was shortened by 30 to 60 minutes proving it to be an efficient method. We suggest though that further studies be needed to evaluate the radiation effect on these patients.

• Journal of the Korea Safety Management & Science
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• v.18 no.1
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• pp.83-88
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• 2016

Currently many geriatric hospitals have been built in Korea because increasing aging rapidly. However the increasing geriatric hospitals make the increasing safety accidents. Therefore this study is conducted by survey and face-to-face talk with the fire safety managers for analyzing safety problem of geriatric hospitals which number is twelve among 15 geriatric hospitals in the north of Chung-buk area. The result of this study is that geriatric hospitals are very old. Fire safety managers holding the fire safety license are a level 2 issued by the Korea Fire Safety Association(KFSA). And the fire safety inspection ability of them is normal (58%). Furthermore a fire safety budget ratio is 83% (A little) in the company yearly budget. And ratio having the fire inspection equipment in the building is 42% (A little) and 33% (Nothing). Satisfaction ratio of their duty is 66% and they also get stress from heavy duty and heavy responsibility. In conclusion, CEO needs to invest and interest the improvement of job performance, satisfaction ratio and fire safety facility. Also government needs the improvement of system to support and supervise the fire safety of geriatric hospitals consistently.

• Journal of Korean Society on Water Environment
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• v.23 no.5
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• pp.731-739
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• 2007

In this study, water quality monitoring focused on TOC was performed at 5 points in Mihocheon (Stream) from January to December 2006. And 10 parameters (water temperature, pH, DO, EC, turbidity, SS, BOD, $PO_4-P$, TOC, TN) were monitored every month for one year. According to this study, TOC increased towards the lower stream (#4~#5). Correlation coefficients between TOC and DO, EC, turbidity, SS, BOD, $PO_4-P$, TN were -0.126, 0.351, 0.320, 0.286, 0.711, 0.525, 0.666. TOC was highly related to BOD. As a result of linear regression analysis, regression equation between BOD and TOC was BOD=0.58TOC+1.90 ($R^2=0.506$). In Mihocheon (Stream), BOD/TOC ratio decreased towards the lower stream. This results show decrease of ratio of biodegradable organic material to total organic pollutants towards the lower stream. This study is significant since it has revealed the potential value of TOC as organic material indicator for inquiry of water quality characteristics in the natural water system.

• Journal of Chest Surgery
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• v.28 no.4
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• pp.346-354
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• 1995

Records of 71 consecutive patients who had received multiple valve replacement were reviewed[34male,37female,mean age 40.5$\pm$11.2 <14-63> . The early death rate was 2.8%[2/71 . A completed follow-up rate of 95.7% was accomplished in these 69 patients who left hospital[mean 42.5 $\pm$29.5 patients-years . Five of these patients died. The late death rate was 7.2%. Four patients experienced anticoagulant-related hemorrhage[all were minor . One patient had a thromboembolic episode[permanent ,and 2 had late prosthetic valve endocarditis. There was no clinical evidence of hemolysis and structural failure of valves used. Of those patients who survived,NYHA functional class improved significantly[from 87.2% class III & IV before to 95.8% class I & II after . Linearized rates for thromboembolism and anticoagulant-related hemorrhage,and for prosthetic valve endocarditis were 0.67%/100 patient-years,2.95%/100 patient-years,1.34%/100 patient-years, respectively. The actuarial estimates of incidence free of all complications and valve-related deaths were 92.2%/patient-years.Despites the advanced heart disease involving two or more native valves, the patients who had multiple valve replacement had very good results, over a 9-year period.

• Journal of Chest Surgery
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• v.48 no.6
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• pp.447-451
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• 2015

This report describes the case of a 57-year-old man with an anterior mediastinal tumor. Four years previously, he underwent laparoscopic anterior resection for sigmoid colon cancer. Thirty months after that procedure, bilateral pulmonary metastasectomy was performed. Twelve months later, follow-up computed tomography revealed a 1-cm pulmonary nodule on the upper lobe of the right lung and a solid mass on the anterior mediastinum, and the patient was also observed to have an elevated serum carcinoembryonic antigen (CEA) level. Repeated pulmonary nodule resection and total thymectomy were performed. Immunohistochemical staining of the anterior mediastinal tumor revealed adenocarcinoma, and his serum CEA level returned to normal after the operation. These findings strongly suggested metastatic thymic adenocarcinoma from a colorectal cancer.

• Journal of Institute of Control, Robotics and Systems
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• v.20 no.8
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• pp.835-841
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• 2014

In this paper we propose a swing-up strategy for a single inverted pendulum. The proposed method has a feature whereby can handle the input and output constraint of a pendulum in a systematic way. For the swing-up of a pendulum, we adopt a 2-DOF control structure that combines the feedforward and feedback control. In order to generate the swing-up feedforward trajectories that satisfy the input and output constraint, we formulate the problem of generating feedforward trajectories as a nonlinear optimal control problem subject to constraints. We illustrate that the proposed method is more flexible than the existing method and provides great freedom in choosing the actuator of the inverted pendulum. Through an experiment, we show that the proposed method can swing a pendulum upward effectively while satisfying all the imposed constraints.

• Journal of Acupuncture Research
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• v.22 no.6
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• pp.201-209
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• 2005

Objectives : We investicated correlation between Yangdorak and Meridian at Idiopathic facial nerve paralysis patients. Methods : For Yangdorak examination, We made a comparison between 21 patients who were diagnosticated to Idiopathic facial nerve paralysis and 22 persons who were not. Results : 1. The stress showed the highest frequency in premonitory cause at onset. 2. In comparing results on the Yangdorak general mean, they were not statistically significant between two group(p<0.05). 3. In comparing results on the Stomach(ST)-meridian Yangdorak mean, Idiopathic facial nerve paralysis group is stastically significant in comparison with non-facial paralysis group(p<0.05). 4. In comparing results on the Small Intestine(SI)-meridian Yangdorak mean, Idiopathic facial nerve paralysis group is not stastically significant in comparison with non-facial paralysis group(p<0.05). Conclusion : Yangdorak may be used for a method to objective clinical examination. But further studies are required for a use of practical indicator.