• Title/Summary/Keyword: Lee Sam

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Synthesis and Antimicrobial Activity of 7-[(3-Methylthio or 3-Methylthiomethyl)pyrrolidinyl] quinolone-3-carboxylic Acid (7-[(3-메틸티오 또는 3-메틸티오메틸)피롤리디닐]퀴놀론-3-카르복실산의 합성과 항균작용)

  • Lee, Jae-Wook;Kang, Tae-Choong;Lee, Kyu-Sam;Son, Ho-Jung;Yoon, Geal-Joong;Yu, Young-Hyo;Kim, Dae-Young
    • YAKHAK HOEJI
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    • v.38 no.2
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    • pp.197-201
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    • 1994
  • A number of 7-[(3-methylthio or methylthiomethyl)pyrrolidiny]qui nolone-3-carboxylic acids were synthesized by condensation of 7-fluoro substituted quinolone-3-carboxylic acid with 3-methylthiopyrrolidine or 3-methylthiomet hylpyrrolidne. 3-Methylthiopyrrolidine or 3-methylthio-methylpyrrolidine which was prepared from N-benzyl-3-hydroxy pyrrolidine or 3-hydroxymethylpyrrolidine. The in vitro antimicrobial activity of them were tested against twenty species of Gram-positive or Gram-negative microorganisms. It showed remarkable antibacterial activity, particularly against Gram-positive microorganisms. Among those 1-cyclopropyl-6,8-difluoro-7-(3-methylthiomethy-lpyrrolidinyl)-1,4-d ihydro-4-oxo-3-quinolinecarboxylic acid(7d) and 1-cyclopropyl-6- fluoro-8-chloro-7-(3-methylthiomethyl pyrrolidinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (7f) showed the most potent in vitro antibacterial activity.

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Sialadenitis caused by iatrogenic trauma: A case report (의원성 사고로 발생한 타액선염:증례보고)

  • Kim Hyun-Woo;Huh Kyung-Hoe;Lee Win-Jin;Heo Min-Suk;Lee Sam-Sun;Choi Soon-Chul
    • Imaging Science in Dentistry
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    • v.34 no.2
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    • pp.107-110
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    • 2004
  • A case of sialadenitis is presented in a patient with painful swelling of the right mouth floor. The condition was caused by trauma on the right mouth floor during dental treatment, which had happened 15 days before admission. On aspiration, mucous secretion was found and ultrasonography showed obstruction of duct. Histopathological studies and surgical investigation established a definite diagnosis of obstructive sialadenitis caused by ductal laceration. As surgical treatment sialodochoplasty was selected. The case and relevant considerations are discussed.

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RADIOLOGIC STUDY OF THE TRAUMATIC BONE CYSTS (외상성 골낭의 방사선학적 연구)

  • CHOI Soon-Chul;LEE Sam-Sun;Lee Geon-Ill
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.24 no.1
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    • pp.7-21
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    • 1994
  • Fifty-two cases of traumatic bone cysts in 50 patients were analysed clinically and radiologically. The obtained results were as follows; 1. Women showed a slightly higher incidence than did men (56% of patients) and the average age proved to be 18.6 years. 2. The majority of the cases were asymptomatic. being detected incidentally. and over the half of the cases occurred in the mandibular symphyseal region. 3. All cases were unilocular and the largest diameter of the lesions varied from 1 to 10㎝, mean 3㎝. 4. Some degree of marginal condensation was present in 28 cases and 23 cases presented pencil-sketch appearance. 5. Many anatomical cortical plates (especially, mandibular inferior cortex and lamina durae) consisted of the margin of the lesions partly. 6. Erosive change of the mandibular inferior cortex was caused by 12 cysts, but cortical expansion only by 3 cysts including 2 cases of buccal expansion. 7. The lesion enveloped the roots of the adjacent teeth in 27 cases and scalloping was present between roots in 17 cases. 8. Lamina dura of the teeth was destroyed by only 1 cyst, and in 1 case root resorption was noticed. But there was no divergence of the roots of teeth.

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Case History: Micropiling for Existing Foundation Retrofits (마이크로파일을 이용한 기초보강공법의 국내 적용 사례)

  • Lee, Jung-Hoon;Choi, Chang-Ho;Cho, Sam-Deok;Lee, Ki-Hwan;Jo, Hyun
    • Proceedings of the Korean Geotechical Society Conference
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    • 2008.03a
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    • pp.359-365
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    • 2008
  • As housing supply ratio has become over 100%, the strategic vision of government's policies has been changed from new construction to maintenance and regeneration of old architectural-structures. This fact has brought a light on the reconstruction and remodeling industries and a need for retrofit and rehabilitation techniques of existing foundation. Various methods of foundation for architectural-structures do exist. Among them, micropiling technologies are increasingly applied in foundation rehabilitation and seismic retrofitting projects. Micropiling techniques provide environmental-friendly methods for minimizing disturbance to adjacent structures, ground, and the environment. The installation is possible in restrictive area and general ground conditions. The fact that the installation procedures cause minimal vibration and noise and require very low ceiling height makes the micropiling methods to be commonly used for underpin existing structures. Specialized drilling equipment is often required to install the micropiles for existing basement facilities. This paper presents a case study in which micropiles were constructed to support a superstructure for vertical extension of existing elevator core and provide accessibility to underground parking lot. It is intended to become useful reference for the similar remodeling project.

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Establishment of Rainfall and Contaminants Runoff Modeling System for the Joman River Watershed Using SWMM (SWMM을 이용한 조만강 유역 강우-오염물 유출모델링시스템 구축)

  • Lee, Yong-Chin;Yoon, Young-Sam;Lee, Nam-Joo
    • Journal of Environmental Science International
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    • v.18 no.9
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    • pp.983-992
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    • 2009
  • The purpose of the present study is to analyze pollutant runoff characteristics from non-point sources in Joman River basin. The present study contains analyzed results of rainfall and SS, BOD, COD, TN, TP runoff from Joman River basin. This study contains a sensitivity analysis of parameters that affect the simulation results of rainfall and pollutants runoff. Result of the sensitivity analysis shows that proportion of watershed and impervious areas is the most sensitive to peak discharge and total flowrate for rainfall runoff and that WASHPO is the most sensitive parameter for pollutants runoff. For parameter estimation and verification, flowrate and water quality is measured at the Kangdong Bridge in Haeban stream. A single rainfall event is use to perform parameter estimation and verification. Results of the present study show that total pollutant loads of Joman River basin is 11,600 ton of SS, 452 ton of BOD, 1,084 ton of COD, 515 ton of TN, and 49 ton of TP, respectively. In addition, it is found that contribution ratio of non point source and total source is 89% of SS, 63% of BOD, 61% of COD, 21% of TN, and 32% of TP, respectively.

남해안의 해수 및 해저퇴적물 용출액과 적조생물 성장과의 관계 연구

  • Lee, Sam-Geun;Lee, Yeong-Sik;Im, Wol-Ae;Jo, Eun-Seop
    • Proceedings of the Korean Environmental Sciences Society Conference
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    • 2007.05a
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    • pp.447-449
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    • 2007
  • 유해성 적조생물인 C. polykrikoides에 대한 해역별 적조잠재력 평가를 위하여 유해성 적조가 자주 발생하는 남해안의 소리도 부근해역, 광양만, 남해도 주변해역, 거제만, 부산연안의 해수 및 해저퇴적물을 채집하여 배양실험을 실시하였다. 실험을 위한 기본배지는 f/2배지에서 배양조건은 온도 $20^{\circ}C$, 염분 34, 조도 2000Lux, 그리고 실험생물은 대수증식기의 C. polykrikoides를 $300cells/m{\ell}$접종하였다. 해역별 해수에 대한 적조생물 성장은 광양만에서 가장 높아 적조발생 잠재력이 가장 높았고, 다음은 부산 기장, 거제, 남해연안 순서로 성장이 높게 나타났으며, 질산성 질소 농도는 $0.35{\sim}24.74{\mu}M$ 범위로 적조생물의 성장과 같은 순서를 나타내었다. 한편 해저 퇴적물 용출액은 적조생물의 성장을 현저히 촉진시켰으며, 남해도 미조연안의 해저 퇴적물 용출액에서 적조발생 잠재력이 가장 높았고, 부산 형제도연안, 광양만, 거제만, 소리도연안의 해저퇴적물 순서로 적조생물의 성장을 촉진시키는 결과를 나타내었다. 그리고 적조생물의 성장은 인산염의 농도에 의해서 성장이 결정되었던 것으로 추정되며, 용출된 인산염의 농도 $1.59{\sim}10.39{\mu}M$ 범위로 남해 미조연안, 부산 형제도 연안, 광양만, 거제만, 소리도 연안 순서로 C. polykrikoides의 성장과 같은 순서로 나타났다.

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IGRINS MIRROR MOUNT DESIGN FOR FIVE FLAT MIRRORS (다섯 개의 평면경을 위한 IGRINS 미러 마운트 설계)

  • Oh, Jae Sok;Park, Chan;Kim, Kang-Min;Chun, Moo-Young;Yuk, In-Soo;Oh, Heeyoung;Jeong, Ueejeong;Yu, Young Sam;Lee, Hanshin;Lee, Sungho
    • Publications of The Korean Astronomical Society
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    • v.30 no.1
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    • pp.17-29
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    • 2015
  • The IGRINS is a near infrared high resolution spectrograph jointly developed by the Korea Astronomy and Space Science Institute and the University of Texas at Austin. We present design and fabrication of the optomechanical mount for the five mirrors, i.e., an input fold mirror, a slit mirror, a dichroic, and two camera fold mirrors. Based on the structure analysis and the thermal analysis of finite element methods, the optomechanical mount scheme satisfies the mechanical and the thermal design requirements given by the optical tolerance analysis. The performance of the fabricated mirror mounts has been verified through three IGRINS commissioning runs.

THE GANUI-DAE AND ITS ASTRONOMICAL ROLE RECORDED IN "THE ANNALS OF THE JOSEON DYNASTY" (『조선왕조실록』에 나타난 간의대의 기록들과 천문학적 연관성)

  • Jeon, Jun Hyeok;Lee, Min-Soo;Kim, Sang Hyuk;Lee, Yong Sam
    • Publications of The Korean Astronomical Society
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    • v.29 no.2
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    • pp.17-27
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    • 2014
  • We report the results of our study for ascertaining whether Ganui-dae built in the Josen Dynasty actually performed an astronomical role or not. The Ganui-dae was the first astronomical structure built as a part of the state astronomical undertakings by King Se-Jong. Our analysis was based on the Annals of the Joseon Dynasty. At first we extracted the records regarding Ganui-dae from the Annals of the Joseon Dynasty and then classified them under six heads according to their astronomical meaning and historical significance. From this analysis we found that the Ganui-dae performed the actual astronomical role. In addition, the provisional offices and peoples mentioned in the records show the astronomical correlation. Generally, when taking into account the functional side of the records, the Ganui-dae was related with the observation. Therefore, the Ganui-dae was the space for the astronomical activity. In conclusion, the Ganui-dae was built for the purpose of the astronomical activity.

Analysis of Material Tests for Predicting and Correcting the Shortening of Vertical Members (수직부재 축소량 예측 및 보정을 위한 재료시험 분석)

  • Park, Hee-Gon;Kwon, Hae-Won;Lee, Jin-Woo;Bae, Yeoun-Ki;Youn, Kang-Sup;Lee, Jae-Sam
    • Proceedings of the Korea Concrete Institute Conference
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    • 2009.05a
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    • pp.173-174
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    • 2009
  • With the recent emergence of high rise buildings, this study was conducted in order to examine shortening, which has been used only in civil engineering structures, in such buildings. Examination of the shortening of vertical members is basically focused on deformations caused by load applied to concrete, material characteristics, etc. Shortening is analyzed through calculating parameters from the factors or characteristics of concrete, but analysis in the aspect of material tests has been somewhat unsatisfactory. Thus, this study purposed to analyze basic material test items for correcting the shortening of vertical members, namely, columns, to determine the reliability of material tests before parameter calculation for correcting shortening, and to examine the performance of material tests.

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