• Journal of Chest Surgery
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• v.3 no.2
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• pp.143-148
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• 1970

Bleomycin is known as a antibiotic agent for malignant tumors especially sguamous cell carcinoma. We have treated 2 cases of malignant tumors, each one esophageal and lung carcinoma with bleomycin, 630 mg and 510 mg respectively. In case of esophageal carcinoma. the subjective symptoms such as dysphagea and swallowing disturbance are temporally relieved, but the irregular filling defect is not significantly changed in esophagogram. In case of lung carcinoma, the atelectasis of right upper lobe on chest X-ray was slightly regressed in its size without effective improvement of subjective symptoms. However, following additional radioactive $^60{Co}$ irradiation therapy (5200r), marked regression of tumor density and aeration of right upper lobe was observed. But 2 weeks later of ceasatioil of irradiatio:J, atelectasis of right upper lobe was again developed. Fever, anorexia, headache and eruption were developed during the treatmeat with bleomycin in both cases but the sign or symptoms of hone marrow depression, renal or liver damage were not noted.

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2002.10a
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• pp.125-125
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• 2002

No Abstract, See Full Text

• Korean Journal of Pharmacognosy
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• v.35 no.1 s.136
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• pp.45-51
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• 2004

Panax ginseng C. A. Meyer (Araliaceae) is listed in Shen Nung Pentsao Ching(神農本草經) as the remedy for replenishing the primodial qi(氣), restoring pulse, treating collapse, tonifing the spleen and lag, promoting the production of body fluid to quench thirst, tranquilizing the mind, and improving the function of brain. The prescriptions of In Sam Tang(人參揚) are also recorded in many other Chinese medical books. The identification of the age of Panax ginseng is very important in commercial market as well as in research field. However, any reports about it have not been clearly established yet. To clarify the criterion, the morphological and anatomical characteristics of the roots of various age Panax ginseng cultivated in Korea were studied. The characteristics of cork layer, secretory canal, and vessel were shown to bε useful keys to confirm the age of Panax ginseng.

• Korean Journal of Pharmacognosy
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• v.31 no.4
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• pp.421-425
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• 2000

HPLC method was applied to the quantitative analysis of lupine alkaloid, matrine from alkaloid fraction of Sophorae Radix (Sophora flavescens). The average content of matrine from 20 Sophorae Radices showed $0.13{\pm}0.06%$.

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2002.10a
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• pp.38-38
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• 2002

No Abstract, See Full Text

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2002.10a
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• pp.71-71
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• 2002

No Abstract, See Full Text

• Korean Journal of Pharmacognosy
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• v.24 no.3
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• pp.219-222
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• 1993

An antihyperglycemic compound in a model of alloxan induced diabetic rats was isolated from the root bark of Aralia elata. The compound identified to be oleanolic acid $28-O-{\beta}-_D-glucopyranoside$ was active at a dose of 100 mg/kg p.o. in the rats. It also has increased the contents of liver glycogen which were lowered by injection of alloxan in the rats.

• Natural Product Sciences
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• v.8 no.4
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• pp.129-132
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• 2002

The MeOH extract of the twig of Morus alba L. (Moraceae) inhibited strong lipid peroxidation activity. In order to find out active principle from the plant, acivity-guided fractionation was performed and five antioxidant compounds were isolated. Their chemical structures were identified as 6-geranylapigenin (1), 6-geranylnorartocarpetin (2), resveratrol (3), oxyresveratrol (4) and quercetin (5) by physicochemical and spectrometric methods. Compounds 1-5 significantly inhibited lipid peroxidation in rat brain homogenate $(IC_{50}\;values\;of\;3.37,\;3.74,\;0.23,\;0.29\;and\;0.06\; {\mu}M,\;respectively)$.

• Korean Journal of Pharmacognosy
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• v.31 no.4
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• pp.416-420
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• 2000

Ursolic acid was isolated from Prunellae Herba (Prunella vulgaris var. lilacina) and identified by direct comparison with an authentic sample. A method of analysis for the evaluation of ursolic acid was developed based on extraction of ground plant material, followed by quantitative determination using capillary gas chromatography of the TMS derivative. Quantitative analysis by GC after derivatisation under mild silylating conditions showed 0.31% ursolic acid in 20 samples collected throughout regions of Korea while no ursolic acid was detected in the samples of the whole plant of Thesium chinense, a substitute for Prunellae Herba in southern regions of Korean peninsula.

• Proceedings of the Korean Society of Life Science Conference
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• 2000.09a
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• pp.102-102
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• 2000