• Korean Journal of Plant Taxonomy
• /
• v.42 no.1
• /
• pp.68-75
• /
• 2012

Two unrecorded species (Sceptridium atrovirens and S. microphyllum), previously known only in Japan, were found in a forest in Dosun-dong, Seogwipo-si, Jeju-do for the first time in Korea. S. atrovirens was distinguished from other related species of the genus Sceptridium in Korea by having the thickest rhizome and root, irregularly crenulate or roughly serrate, and a shorter sporophore blade. The local name was newly given as 'Sup-go-sa-ri-sam' for the species, denoting the habitat. S. microphyllum was distinguished by having the smallest plant height, compact sterile blades, and partly lateritious tropophyll in winter. The local name was newly given as 'Aegi-go-sa-ri-sam' for species, meaning of a small size. To reveal the interspecific relationships within the genus Sceptridium in Korea, cladistic analysis was performed for 27 morphological characteristics. The morphological characteristics and illustrations of the two taxa, as well as photographs at the habitat, are provided with a taxonomic key to the species of Sceptridium in Korea.

• Korean Journal of Remote Sensing
• /
• v.30 no.2
• /
• pp.227-239
• /
• 2014

This study aims to evaluate performance of various image fusion methods based on the spectral responses of high-resolution optical satellite sensors such as KOMPSAT-2, QuickBird and WorldView-2. The image fusion methods used in this study are GIHS, GIHSA, GS1 and AIHS. A quality evaluation of each image fusion method was performed with both quantitative and visual analysis. The quantitative analysis was carried out using spectral angle mapper index (SAM), relative global dimensional error (spectral ERGAS) and image quality index (Q4). The results indicates that the GIHSA method is slightly better than other methods for KOMPSAT-2 images. On the other hand, the GS1 method is suitable for Quickbird and WorldView-2 images.

• Macromolecular Research
• /
• v.15 no.4
• /
• pp.348-356
• /
• 2007

The aim of this study was to fabricate a submicro-and micro-patterned fibronectin coated wafer for a cell culture, which allows the positions and dimensions of the attached cells to be controlled. A replica molding was made into silicon via a photomask in quartz, using E-beam lithography, and then fabricated a polydimethylsiloxane stamp using the designed silicon mold. Hexadecanethiol $[HS(CH_2){_{15}}CH_3]$, adsorbed on the raised plateau of the surface of polydimethylsiloxane stamp, was contact-printed to form self-assembled monolayers (SAMs) of hexadecanethiolate on the surface of an Au-coated glass wafer. In order to form another SAM for control of the surface wafer properties, a hydrophilic hexa (ethylene glycol) terminated alkanethiol $[HS(CH_2){_{11}}(OCH_2CH_2){_6}OH]$ was also synthesized. The structural changes were confirmed using UV and $^1H-NMR$ spectroscopies. A SAM terminated in the hexa(ethylene glycol) groups was subsequently formed on the bare gold remaining on the surface of the Aucoated glass wafer. In order to aid the attachment of cells, fibronectin was adsorbed onto the resulting wafer, with the pattern formed on the gold-coated wafer confirmed using immunofluorescence staining against fibronectin. Fibronectin was adsorbed only onto the SAMs terminated in the methyl groups of the substrate. The hexa (ethylene glycol)-terminated regions resisted the adsorption of protein. Human dermal fibroblasts (P=4), obtained from newborn foreskin, only attached to the fibronectin-coated, methyl-terminated hydrophobic regions of the patterned SAMs. N-HDFs were more actively adhered, and spread in a pattern spacing below $14{\mu}m$, rather than above $17{\mu}m$, could easily migrate on the substrate containing spacing of $10{\mu}m$ or less between the strip lines.

• The Journal of Pediatrics of Korean Medicine
• /
• v.20 no.3
• /
• pp.33-50
• /
• 2006

Objectives : Oriental medicine has set the no herb medicamentous dose for child, on the other hand the western medicine has it standardizing of age, weight or dimension of body. Therefore, we aimed to research the herb medicamentous dose for child being in being used in clinic. Methods : We made up a question of the oriental medical doctors of the master's and doctor's course in ○○ university. Results : 1. Child dose of herb medicine a time likes this. 1 pack is written prescription most at children patients under 1 year. 1 pack and 2 packs are written prescription most at children patients over 1 under 2. 2 packs are written prescription most at children patients over 2 under 3. 4 packs are written prescription most at children patients over 3 under 4. 10 packs are written prescription most at children patients over 8 under 14. Dose of herb medicine written prescription at children patients over 5 under 8 is in decentralization from 2 to 10 packs. 2. 2 or 3 times are most in a number of taking medicine a day. 3. 3 days are common in period of taking medicine under 5, over 10 days are common over 5. 4. It is necessary to regulating child dose of herb medicine.

• Korean Journal of Animal Reproduction
• /
• v.26 no.4
• /
• pp.385-394
• /
• 2002

This study was constructed the correlations of the embryonic developmental rates and the frequency of chromosome aberration using ear-skin-fibroblast cell in nuclear transfer (NT) derived embryos. Karyoplast-oocyte complexes were fused and activated simultaneously, then cultured for seven days to assess development. The developmental rates of NT and in vitro fertilization (IVF) embryos were 55.4% vs 63.5%, 31.7% vs 33% and 13.4% vs 16.8% in 2 cell, 8 cell and blastocyst, respectively. Firstly, the frequency of chromosome aberrations were evaluated using fluorescent in situ hybridization (FISH) technique with porcine chromosome 1 submetacentric specific probe. Chromosome aberration was detected at day 3 on the embryo culture, the percentages of chromosomal aneuploidy in NT and IVF embryos at 4-cell stage were 40%, 31.3%, respectively. Secondly, embryonic fragmentation was evaluated at 4-cell stage embryo. Frequency of embryonic fragmentations was in 51.3% of NT, 61.3% of IVF, 28.9% of parthenogenetic activation at 4-cell stage. The proportion of fragmentation in NT embryos was higher than activation embryos. This result indicates that chromosomal abnormalities and embryonic fragments are associated with low developmental rate in porcine NT embryo. It is also suggest that abnormal porcine embryos produced by NT related with lower implantation rate, increased abortion rate and production of abnormal fetuses.

• The Journal of Internal Korean Medicine
• /
• v.26 no.1
• /
• pp.281-289
• /
• 2005

Objective : Pheochromocytoma may arise within the adrenal medulla, or in other locations, where symptheic ganglia or chromaffin tissues are known to exist. Approximately 0.1 % of hypertensive patients have Pheochromocytoma, This study is to report the clinical effects of ShiHo-GuiZhiTang on pateints who have suffered from such symptoms of Pheochromocytoma as sweating, hypertention, Indigestion, anxiety neurosis, nausea, headache, and epigastric discomfort. Method : ShiHo-GuiZhiTang was used for a patient who had suffered from symptoms of Pheochromocytoma which was diagnosed as Banpeubanri-jueng of soyang disease in Sanghan-Ron. Result : In treating the patient with symptoms of Pheochromocytoma with ShiHo-GuiZhiTang, results were good. Conclusion : The results of this study suggest that ShiHo-GuiZhiTang is effective for such symptoms of Pheochromocytoma as sweating, hypertention, Indigestion, anxiety neurosis, nausea, headache, and epigastric discomfort.

• Korean Journal of Materials Research
• /
• v.1 no.4
• /
• pp.191-197
• /
• 1991

The surface roughnesses of titanium silicide films and the diffusion behaviours of dopants in single crystal and polycrystalline silicon substrates durng titanium silicide formation by rapid thermal annealing(RTA) of sputter deposited Ti-filicide film from the composite $TiSi_{2.6}$ target were investigated by the secondary ion mass spectrometry(SIMS), a four-point probe, X-ray diffraction, and surface roughness measurements. The as-deposited films were amorphous but film prepared on single silicon substrate crystallized to the orthorhombic $TiSi_2$(C54 structure) upon rapid thermal annealing(RTA) at $800^{\circ}C$ for 20sec. There was no significant out-diffusion of dopants from both single crystal and polycrystalline silicon substrate into titanum silicide layers during annealing. Most of the implanted dopants piled up near the titanium silicide/silicon interface. The surface roughnesses of titanium silicide films were in the range between 16 and 22nm.

• Korean Journal of Clinical Pharmacy
• /
• v.19 no.1
• /
• pp.23-31
• /
• 2009

The aim of this study was to evaluate the pharmacokinetic parameters of two risedronate preparations. The clinical assessment was conducted on 46 healthy volunteers who received one tablet (Risedronate sodium 35 mg/tablet) in the fasting state, in a randomized balanced $2{\times}2$ cross-over study design. After dosing of one tablet containing 35 mg risedronate sodium, blood samples were collected serially for a period of 48 hours. Plasma was analyzed for risedronate by using LC/MS/MS assay method. The analysis system was validated in specificity, accuracy, precision, and linearity. $AUC_t$, (the area under the plasma concentration-time curve from the zero-time to 48 hr) was calculated through the trapezoidal rule. $C_{max}$ (maximum plasma drug concentration) were compiled from the plasma risedronate concentration-time data of each volunteer. No significant sequence effect was found for the pharmacokinetic parameters indicating that the cross-over design was properly performed. The 90 % - Confidence intervals of the $AUC_t$ ratio and the $C_{max}$ were from log 0.8752 to log 1.1888 and log 0.8457 to log 1.1478, respectively. These values were within the acceptable intervals between 0.80 and 1.25. Therefore, this study demonstrated that no statistically significant difference was identified with respect to the rate and extent of absorption.

• Journal of KIISE:Computing Practices and Letters
• /
• v.15 no.12
• /
• pp.918-922
• /
• 2009

Naturally, block mapping FTL works well for sequential writes while page mapping FTL does well for random writes. To exploit their advantages, a practical FTL should be able to selectively apply a suitable scheme between page and block mappings for each write pattern. To meet that requirement, we propose a hybrid mapping FTL, which we call Janus-FTL, that distributes data to either block or page mapping areas. Also, we propose the fusion operation to relocate the data from block mapping area to page mapping area and the defusion operation to relocate the data from page mapping area to block mapping area. And experimental results of Janus-FTL show performance improvement of maximum 50% than other hybrid mapping FTLs.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2012.05a
• /
• pp.464-464
• /
• 2012

수문분야에 있어서 빈도해석의 목적은 특정 재현기간에 대한 발생 가능한 수문량의 규모를 파악하는데 있으며, 빈도해석의 정확도는 적합한 확률분포모형의 선택과 매개변수 추정방법에 의존하게 된다. 일반적으로 각 확률분포모형의 특성을 대표하는 매개변수를 추정하기 위해서는 모멘트 방법, 확률가중 모멘트 방법, 최대우도법 등을 이용하게 된다. 모멘트 방법에 의한 매개변수 추정은 해를 구하기 위한 과정이 단순한 반면, 비대칭형의 왜곡된 분포를 갖는 자료들에 대해서는 부정확한 결과를 나타내게 된다. 확률가중 모멘트 방법은 표본의 크기가 작거나 왜곡된 자료일 경우에도 비교적 안정적인 결과를 제공하는 반면, 확률 가중치가 정수로만 제한되는 단점을 갖고 있다. 그리고 대수 우도함수를 이용하여 매개변수를 추정하게 되는 최우도법은 가장 효율적인 매개변수 추정치를 얻을 수 있는 것으로 알려져 있으나, 비선형 연립방정식으로 표현되는 해를 구하기 위해서는 Newton-Raphson 방법을 사용하는 등 절차가 복잡하며, 때로는 수렴이 되지 않아 해룰 구하지 못하는 경우가 발생되게 된다. 이에 반해, 최근의 Genetic Algorithm, Ant Colony Optimization 및 Simulated Annealing과 같은 Meta-Heuristic Algorithm들은 복잡합 공학적 최적화 문제 있어서 효율적인 대안으로 주목받고 있으며, Hassanzadeh et al.(2011)에 의해 수문학적 빈도해석을 위한 매개변수 추정에 있어서도 그 적용성이 검증된바 있다. 본 연구의 목적은 연 최대강수 자료의 빈도해석에 적용되는 확률분포모형들의 매개변수 추정을 위해 Meta-Heuristic Algorithm을 적용하고자 함에 있다. 따라서 본 연구에서는 매개변수 추정을 위한 방법으로 Genetic Algorithm 및 Harmony Search를 적용하였고, 그 결과를 최우도법에 의한 결과와 비교하였다. GEV 분포를 이용하여 Simulation Test를 수행한 결과 Genetic Algorithm을 이용하여 추정된 매개변수들은 최우도법에 의한 결과들과 비교적 유사한 분포를 나타내었으나 과도한 계산시간이 요구되는 것으로 나타났다. 하지만 Harmony Search를 이용하여 추정된 매개변수들은 최우도법에 의한 결과들과 유사한 분포를 나타내었을 뿐만 아니라 계산시간 또한 매우 짧은 것으로 나타났다. 또한 국내 74개소의 강우관측소 자료와 Gamma, Log-normal, GEV 및 Gumbel 분포를 이용한 실증연구에 있어서도 Harmony Search를 이용한 매개변수 추정은 효율적인 매개 변수 추정치를 제공하는 것으로 나타났다.