• Title/Summary/Keyword: Lee In-Bae

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Growth-Inhibiting Effect of Bufadienolides on Cultured Vascular Endothelial Cells

  • Lee, Duck-Yoon;Yoon, Hwa-Joong
    • Toxicological Research
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    • v.11 no.2
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    • pp.175-180
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    • 1995
  • We found that bufalln, one of the prominent components of the bufadlenolides in the Chinese medicine chan'su, has the potent inhibitory effects on growth and proliferation of the cultured bovine aortlc endothelial (BAE) and human umbilical vein endothelial (HUVE) cells. All naturally-occuring bufadienolides used in this study inhibited the cell growth in a dose-dependent manner. Particularly, bufalin among the bufadienolides showed the strongest inhibitory activity for the cell growth. The order of growth inhibition by bufadienolides on BAE cells was as follows: bufalin > gamabufotalln > bufotalln > cinobufagin > cinobufotalin > resibufogenin. The $IC_50$ values (50% inhibition of cell growth) of bufalin as determined by XTT assay were the range of 1-10 nM in BAE and HUVE cells. Bufalin exhibited a higher sensitivity towards cultured bovine aortic endothelial cells than human umbilical vein endothelial cells.

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GC-MS Analysis of Diterpene Quinone Constituents of Salviae Miltiorrhizae Radix and Biological Activity

  • Park, Hee-Juhn;Lee, Seung-Bae;Lee, Eun;Cha, Bae-Chun;Park, Moo-Young;Lee, Sung-Mok;Chung, Won -Tae
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.3
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    • pp.459-465
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    • 1995
  • The ether extract of Salviae miltiorrhizae Radix(SMR) was fractioned to give five subfractions, so that two subfractions of them were recrystallized to yield each pure diterpene quinone pigment. On the basis of spectral evidence, these two compounds were identified as tanshinone II and crytotanshinone. Cryptotanshinone exhibited both of a potent platelet anti-aggregating activity in vitro and a potent antimicrobial activity. GC-MS analysis of the other extract showed that tanshinone II was contained in the largest proportion of all the diterpene quinones. In addition, GC-MS analysis gave other valuable analytical informations.

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Origin of Chinese Cabbage(Pe-tsai) (배추(숭(崧))의 어원(語源) 연구)

  • Kim, Jong-Dug;Lee, Eun-Hee
    • Journal of Sasang Constitutional Medicine
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    • v.19 no.3
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    • pp.20-29
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    • 2007
  • 1. Objectives We know that the origine of the pe-tsai is from 백채(白菜; pronounced as bak-tsai, meaning white vegetable). But some literatures said that the japanese butterbur(Petasites japonicus (Sieb. et Zucc.) Maxim) is from 백채(白菜;: pronounced as bak-tsai), too. These two words have same origin. It makes us get into a mess. So We are about to study the origine of the pe-tsai more. Also, we investigated its historical origin, properties and Sasang constitutional medicine's efficacy. 2. Methods We reviewed farmings(e.g. 山林經濟, 林園經濟法), dictionarys(e.g. 訓蒙字會), encyclopedia(e.g. 物名攷), books on herbs and medicines to summarize literatures about the pe-tsai. 3. Results and Conclusions (1) The origin of term, pe-tsai is sung, named after a pine tree(松), chineses character pronounced as song) which we can see throughout a year. Also, pe-tsai was called white vegetables(白菜, pronounced as bak-tsai) because its appearance is green and white. Therefore, the pronounciation of sung derives from its character and we also say bak-tsai(白菜), which came from its looks. (2) Today we pronounce pe-tsai inro bae-tsu(배추) in korean. There are pronunciational developments of this word : bak-tsai(白菜) $\to$ bae-tsae $\to$ bae-tsa $\to$ bae-tsa $\to$ bae-tsae(배채) $\to$ bae-tsu(배추). (3) Our ancestor used bak-tsai(白菜) as the name of japenese butterbur, which was different from China. The latter times of Joseon(조선), however, sometimes bak-tsai(白菜) meant pe-tsai. After the year of 1800, bak-tsai(白菜) only meant pe-tsai. So when we try to translate our ancestor's books, we must examine carefully their published year. (4) Pe-tsai is used for baby's erysipelas, boil, fever in the chest, thirst after alcohol drinking and kind of diabetes. It helps digestive organs as well. Pe-tsai is used for stress, fever in the chest and cough with fever of Soyangin and Tayangin in Sasang Constitutional Medicine.

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Design of Tunable Flat-top Bandpass Filter Based on Two Long-period Fiber Gratings and Core Mode Blocker

  • Bae, Jin-Ho;Bae, Jun-Kye;Lee, Sang-Bae
    • Journal of the Optical Society of Korea
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    • v.15 no.2
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    • pp.202-206
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    • 2011
  • We propose a tunable flat-top bandpass filter to pass light in a customized wavelength band by using long-period fiber gratings (LPFG) structure. The LPFG structure is composed of a core mode blocker in between two LPFGs. The bandpass spectrum of the proposed structure is obtained in overlapped wavelength band of two LPFGs operating on the same modes. To analyze the properties, we introduce a mathematical matrix model for the structure. We theoretically demonstrate flexibility of the flat-top bandpass filter with various bandwidths.