• Title/Summary/Keyword: Lee Geun-sam

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Co 이온이 주입된 GaN의 특성

  • Kim, U-Cheol;Gang, Hui-Jae;O, Seok-Geun;Song, Jong-Han;Lee, Jong-Han;Sin, Sang-Won;No, Sam-Gyu;O, Sang-Jun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2004.08a
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    • pp.132-132
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    • 2004

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Experimental Study on the Antidepressant Effect of Sam-Jeong-Hwan (삼정환(三精九)의 항우울 효과에 대한 실험적 연구)

  • Lee, Sang-Taek;Kim, Geun-Woo;Koo, Byung-Soo
    • Journal of Oriental Neuropsychiatry
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    • v.19 no.3
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    • pp.101-115
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    • 2008

  • Objective: The purpose of this study was to investigate the protective effects of Sam-Jeong-Hwan(SJH) on the animal model of depression induced immobilization stress. Method: The subject were divided into 4 groups(l. normal 2. saline solution administered during immobilization stress treatment 3. SJH of 100mg/kg administered 4. BKJ of 400mg/kg administered). Immobilization stress was treated for 1 hours on day. During 2 days of immobilization stress treatment, they were executed forced swimming test, passive avoidance test, elevated plus maze test. Corticosterone and ACTH in blood were measured. Results: In forced swimming test, SJH of 400mg/kg group showed decreased immobilization. In passive avoidance test, SJH of 400mg/kg group showed increased learning execution. In EPM test, SJH of 400mg/kg group showed decreased anxiety. In locomotor activity test, SJH groups showed significantly increased locomotor activity. Stress group showed significantly increase in serum level of corticosterone, SJH of 400mg/kg group showed decreased serum level of corticosterone. Stress group showed significantly increase in serum level of ACTH, SJH of 400mg/kg group showed decreased serum level of ACTH. Conclusion: These results suggest that Sam-Jeong-Hwan(SJH) is effective in the treatment of depression.

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