• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.33 no.1
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• pp.1-6
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• 2022

Vocal fold injection (VFI) is widely accepted as a first line treatment in treating unilateral vocal fold paralysis and other vocal fold diseases. Although VFI is advantageous for its minimal invasiveness and efficiency, the invisibility of the needle tip remains an essential handicap in precise localization. Real-time light-guided vocal fold injection (RL-VFI) is a novel technique that was developed under the concept of performing simultaneous injection with precise placement of the needle tip under light guidance. RL-VFI has confirmed its possibility of technical implementation and the feasibility in injecting the needle from various directions through ex vivo animal studies. Further in vivo animal study has approved the safety and feasibility of the procedure when various transcutaneous approaches were applied. Currently, RL-VFI device is authorized for clinical use by the Ministry of Food and Drug Safety in South Korea and is clinically applied to patients with safe and favorable outcome. Several clinical studies are currently under process to approve the safety and the efficiency of RL-VFI. RL-VFI is expected to improve the complication rate and the functional outcome of voice. Furthermore, it will support laryngologists in overcoming the steep learning curve by its intuitive guidance.

• Journal of Broadcast Engineering
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• v.27 no.5
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• pp.812-815
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• 2022

Images displayed on a digital devices under the sunlight are generally perceived to be darker than the original images, which leads to a decrease in visibility. For better visibility, global luminance compensation or tone mapping adaptive to ambient lighting is required. However, the existing methods have limitations in chrominance compensation and are difficult to use in real world due to their heavy computational cost. To solve these problems, this paper propose a piece-wise linear curves (PLECs)-based image enhancement method to improve both luminance and chrominance. At this time, PLECs are regressed through deep learning and implemented in the form of a lookup table to real-time operation. Experimental results show that the proposed method has better visibility compared to the original image with low computational cost.

• Clinics in Shoulder and Elbow
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• v.24 no.4
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• pp.209-214
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• 2021

Background: The treatment for acromioclavicular joint injuries (ACJI) ranges from a conservative approach to extensive surgical reconstruction, and the decision on how to manage these injuries depends on the grade of acromioclavicular (AC) joint separation, resources, and skill availability. After a thorough review of the literature, the researchers adopted a simple cost-effective technique of AC joint reconstruction for acute ACJI requiring surgery. Methods: This was a prospective single-center study conducted between April 2017 and April 2018. For patients with acute ACJI more than Rockwood grade 3, the researchers performed open coracoclavicular ligament reconstruction using synthetic sutures along with an Endobutton and a figure of 8 button plate. This was followed by AC ligament repair augmenting it with temporary percutaneous AC K-wires. Clinical outcomes were evaluated using the Constant Murley shoulder score. Results: Seventeen patients underwent surgery. The immediate postoperative radiograph showed an anatomical reduction of the AC joint dislocation in all patients. During follow-up, one patient developed subluxation but was asymptomatic. The mean follow-up period was 30 months (range, 24-35 months). The mean Constant score at 24 months was 95. No AC joint degeneration was noted in follow-up X-rays. The follow-up X-rays showed significant infra-clavicular calcification in 11 of the 17 patients, which was an evidence of a healed coracoclavicular ligament post-surgery. Conclusions: This study presents a simple cost-effective technique with a short learning curve for anatomic reconstruction of acute ACJI. The preliminary results have been very encouraging.

• Journal of Biomedical Engineering Research
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• v.44 no.1
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• pp.25-32
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• 2023

Recognizing the size and location of prostate cancer is critical for prostate cancer diagnosis, treatment, and predicting prognosis. This paper proposes a model to classify the tumor region and normal tissue with cross-sectional visual images of prostatectomy tissue. We used specimen images of 44 prostate cancer patients who received prostatectomy at Gachon University Gil Hospital. A total of 289 prostate slice images consist of 200 slices including tumor region and 89 slices not including tumor region. Images were divided based on the presence or absence of tumor, and a total of 93 features from each slice image were extracted using Radiomics: 18 first order, 24 GLCM, 16 GLRLM, 16 GLSZM, 5 NGTDM, and 14 GLDM. We compared feature selection techniques such as LASSO, ANOVA, SFS, Ridge and RF, LR, SVM classifiers for the model's high performances. We evaluated the model's performance with AUC of the ROC curve. The results showed that the combination of feature selection techniques LASSO, Ridge, and classifier RF could be best with an AUC of 0.99±0.005.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.212-212
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• 2023

비점오염원관리와 같이 장기적인 유역 관리 계획에서 유역 내 오염원 평가는 정말 중요하다. 유역 내 오염원 평가는 강우 유출에 의한 비점오염 발생원이 어디서 얼마나 발생시키는지에 대한 정량적인 조사가 필요하다. 유역 내의 오염원에 대한 정량적인 조사는 많은 비용과 시간이 필요하다. 이러한 비용과 시간을 줄이기 위해 유역단위 수리 수문 모델을 사용하고 있다. 유역단위 수리수문 모델은 HSPF (Hydrological Simulation Program in Fortran), SWAT (Soil and Water Assessment Tool), L-THIA ACN-WQ(The Long-term Hydrologic Impact Assessment Model with Asymptotic Curve Number Regression Equation and Water Quality model)등 다양한 모델이 사용되고 있다. 하지만 유역 모델을 통한 모의는 다양한 연산 과정을 진행하여 모의까지 많은 시간이 필요하다는 단점이 있다. 이에 따라 데이터 기반 모델링 기법(머신러닝/딥러닝)을 이용한 유출 및 수질 예측 연구가 많이 이루어지고 있다. 단순 머신러닝/딥러닝 기반 모델링 기법은 점(최종유출구)에서의 예측만 가능하여 최적관리 기법 적용 등과 같은 유역관리 방안을 적용하기 힘들다는 문제점이 있다. 따라서 본 연구에서 머신러닝/딥러닝을 통해 일부 수문 프로세스를 대체하고 소유역별 하도추적 기법을 연계하여 유량 및 수질 항목들의 모의가 가능한 하이브리드 모델을 개발하였다. 이는 머신러닝/딥러닝이 유역 모델의 일부 연산 과정을 대체하여 모의시간이 빠르며, 기존 머신러닝/딥러닝 예측 모델에서 평가가 어려웠던 유역 관리 방안 및 최적관리기법 적용 평가에도 활용이 가능할 것으로 판단이 된다.

• Journal of the Korea Society of Computer and Information
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• v.28 no.9
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• pp.149-158
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• 2023

With the global paradigm shift towards climate change, the shipbuilding industry is also considering propulsion systems that utilize eco-friendly fuels various propulsion systems are gaining attention as a result. In conventional propulsion systems, typically consisting of propellers and rudders, have evolved into a diverse range of systems due to the development of a special propulsion system known as the azimuth thruster. While azimuth thrusters were previously commonly installed on tugboats, they are now extensively used on offshore plant operation ships equipped with dynamic positioning systems. However, these azimuth thrusters require different steering methods compared to conventional propulsion systems, leading to a significant learning curve for the crew members boarding such vessels. Furthermore the availability of education related to these special propulsion systems is limited. This study aims to analyze accidents caused by inadequate control of vessels equipped with azimuth thrusters using the STAMP technique. And it proposes the necessity of standard steering commands for the safe operation of vessels equipped with special propellers.

• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.112-112
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• 2020

하천에서 유해화학물질 유입 사고 발생 시 수환경 피해를 최소화하기 위해 신속한 초기 대응이 필요하다. 따라서, 본 연구에서는 수환경 화학사고 대응 시스템 구축을 위해 하천 실시간 모니터링 지점에서 관측된 유해화학물질의 농도 자료를 이용하여 발생원의 유입 지점과 유입량을 역추적하는 프레임워크를 개발하였다. 본 연구에서 제시하는 프레임워크는 첫 번째로 하천 저장대 모형(Transient Storage Zone Model; TSM)과 HEC-RAS 모형을 이용하여 다양한 유량의 수리 조건에서 화학사고 시나리오를 생성하는 단계, 두번째로 생성된 시나리오의 유입 지점과 유입량에 대한 시간-농도 곡선 (BreakThrough Curve; BTC)을 21개의 곡선특징 (BTC feature)으로 추출하는 단계, 최종적으로 재귀적 특징 선택법(Recursive Feature Elimination; RFE)을 이용하여 의사결정나무 모형, 랜덤포레스트 모형, Xgboost 모형, 선형 서포트 벡터 머신, 커널 서포트 벡터 머신 그리고 Ridge 모형에 대한 모형별 주요 특징을 학습하고 성능을 비교하여 각각 유입 위치와 유입 질량 예측에 대한 최적 모형 및 특징 조합을 제시하는 단계로 구축하였다. 또한, 현장 적용성 제고를 위해 시간-농도 곡선을 2가지 경우 (Whole BTC와 Fractured BTC)로 가정하여 기계학습 모형을 학습시켜 모의결과를 비교하였다. 제시된 프레임워크의 검증을 위해서 낙동강 지류인 감천에 적용하여 모형을 구축하고 시나리오 자료 기반 검증과 Rhodamine WT를 이용한 추적자 실험자료를 이용한 검증을 수행하였다. 기계학습 모형들의 비교 검증 결과, 각 모형은 가중항 기반과 불순도 감소량 기반 특징 중요도 산출 방식에 따라 주요 특징이 상이하게 산출되었으며, 전체 시간-농도 곡선 (WBTC)과 부분 시간-농도 곡선 (FBTC)별 최적 모형도 다르게 산출되었다. 유입 위치 정확도 및 유입 질량 예측에 대한 R²는 대부분의 모형이 90% 이상의 우수한 결과를 나타냈다.

• Smart Structures and Systems
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• v.31 no.3
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• pp.229-245
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• 2023

The absence of excitation measurements may pose a big challenge in the application of structural damage identification owing to the fact that substantial effort is needed to reconstruct or identify unknown input force. To address this issue, in this paper, an iterative strategy, a synergy of Tikhonov regularization method for force identification and modified Jaya algorithm (M-Jaya) for stiffness parameter identification, is developed for damage identification with partial output-only responses. On the one hand, the probabilistic clustering learning technique and nonlinear updating equation are introduced to improve the performance of standard Jaya algorithm. On the other hand, to deal with the difficulty of selection the appropriate regularization parameters in traditional Tikhonov regularization, an improved L-curve method based on B-spline interpolation function is presented. The applicability and effectiveness of the iterative strategy for simultaneous identification of structural damages and unknown input excitation is validated by numerical simulation on a 21-bar truss structure subjected to ambient excitation under noise free and contaminated measurements cases, as well as a series of experimental tests on a five-floor steel frame structure excited by sinusoidal force. The results from these numerical and experimental studies demonstrate that the proposed identification strategy can accurately and effectively identify damage locations and extents without the requirement of force measurements. The proposed M-Jaya algorithm provides more satisfactory performance than genetic algorithm, Gaussian bare-bones artificial bee colony and Jaya algorithm.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.307-307
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• 2022

최근 기후변화와 댐 상류 토지이용 변화 등과 같은 다양한 원인에 의해 댐 유입량의 변동성이 증가하면서 댐 관리 및 운영조작 의사 결정에 어려움이 발생하고 있다. 따라서 이러한 댐 유입량의 변동 특성을 반영하여 댐 유입량을 정확하고 효율적으로 예측할 수 있는 방안이 필요한 실정이다. 머신러닝 기술이 발전하면서 Auto-ML(Automated Machine Learning)이 다양한 분야에서 활용되고 있다. Auto-ML은 데이터 전처리, 최적 알고리즘 선택, 하이퍼파라미터 튜닝, 모델 학습 및 평가 등의 모든 과정을 자동화하는 기술이다. 그러나 아직까지 수문 분야에서 댐 유입량을 예측하기 위한 모델을 개발하는데 있어서 Auto-ML을 활용한 사례는 부족하고, 특히 댐 유입량의 예측 정확성을 확보하기 위해 High-inflow and low-inflow 의 변동 특성을 고려한 하이브리드 결합 방식을 통해 Auto-ML 기반 앙상블 모델을 개발하고 평가한 연구는 없다. 본 연구에서는 Auto-ML의 패키지 중 Auto-sklearn을 통해 홍수기, 비홍수기 유입량 변동 특성을 반영한 하이브리드 앙상블 댐 유입량 예측 모델을 개발하였다. 소양강댐을 대상으로 적용한 결과, 하이브리드 Auto-sklearn 앙상블 모델의 댐 유입량 예측 성능은 R² 0.868, RMSE 66.23 m³/s, MAE 16.45 m³/s로 단일 Auto-sklearn을 통해 구축 된 앙상블 모델보다 전반적으로 우수한 것으로 나타났다. 특히 FDC (Flow Duration Curve)의 저수기, 갈수기 구간에서 두 모델의 유입량 예측 경향은 큰 차이를 보였으며, 하이브리드 Auto-sklearn 모델의 예측 값이 관측 값과 더욱 유사한 것으로 나타났다. 이는 홍수기, 비홍수기 구간에 대한 앙상블 모델이 독립적으로 구축되는 과정에서 각 모델에 대한 하이퍼파라미터가 최적화되었기 때문이라 판단된다. 향후 본 연구의 방법론은 보다 정확한 댐 유입량 예측 자료를 생성하기 위한 방안 수립뿐만 아니라 다양한 분야의 불균형한 데이터셋을 이용한 앙상블 모델을 구축하는데도 유용하게 활용될 수 있을 것으로 사료된다.

• Korean Journal of Radiology
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• v.22 no.4
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• pp.535-546
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• 2021

Objective: To evaluate the feasibility of texture analysis on non-contrast-enhanced T1 maps of cardiac magnetic resonance (CMR) imaging for the diagnosis of myocardial injury in acute myocardial infarction (MI). Materials and Methods: This study included 68 patients (57 males and 11 females; mean age, 55.7 ± 10.5 years) with acute ST-segment-elevation MI who had undergone 3T CMR after a percutaneous coronary intervention. Forty patients of them also underwent a 6-month follow-up CMR. The CMR protocol included T2-weighted imaging, T1 mapping, rest first-pass perfusion, and late gadolinium enhancement. Radiomics features were extracted from the T1 maps using open-source software. Radiomics signatures were constructed with the selected strongest features to evaluate the myocardial injury severity and predict the recovery of left ventricular (LV) longitudinal systolic myocardial contractility. Results: A total of 1088 segments of the acute CMR images were analyzed; 103 (9.5%) segments showed microvascular obstruction (MVO), and 557 (51.2%) segments showed MI. A total of 640 segments were included in the 6-month follow-up analysis, of which 160 (25.0%) segments showed favorable recovery of LV longitudinal systolic myocardial contractility. Combined radiomics signature and T1 values resulted in a higher diagnostic performance for MVO compared to T1 values alone (area under the curve [AUC] in the training set; 0.88, 0.72, p = 0.031: AUC in the test set; 0.86, 0.71, p = 0.002). Combined radiomics signature and T1 values also provided a higher predictive value for LV longitudinal systolic myocardial contractility recovery compared to T1 values (AUC in the training set; 0.76, 0.55, p < 0.001: AUC in the test set; 0.77, 0.60, p < 0.001). Conclusion: The combination of radiomics of non-contrast-enhanced T1 mapping and T1 values could provide higher diagnostic accuracy for MVO. Radiomics also provides incremental value in the prediction of LV longitudinal systolic myocardial contractility at six months.