KIPS Transactions on Computer and Communication Systems
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v.10
no.10
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pp.277-284
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2021
Recently, the smart home environment is expected to be a platform that collects, integrates, and utilizes various data through convergence with wireless information and communication technology. In fact, the number of smart devices with various sensors is increasing inside smart homes. The amount of data that needs to be processed by the increased number of smart devices is also increasing, and big data processing systems are actively being introduced to handle it effectively. However, traditional big data processing systems have all requests directed to cluster drivers before they are allocated to distributed nodes, leading to reduced cluster-wide performance sharing as cluster drivers managing segmentation tasks become bottlenecks. In particular, there is a greater delay rate on smart home devices that constantly request small data processing. Thus, in this paper, we design a Apriori-based big data system for effective data processing in smart home environments where frequent requests occur at the same time. According to the performance evaluation results of the proposed system, the data processing time was reduced by up to 38.6% from at least 19.2% compared to the existing system. The reason for this result is related to the type of data being measured. Because the amount of data collected in a smart home environment is large, the use of cache servers plays a major role in data processing, and association analysis with Apriori algorithms stores highly relevant sensor data in the cache.
Gaire, Bhakta Prasad;Bae, Young Joo;Choi, Ji Woong
Biomolecules & Therapeutics
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v.27
no.6
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pp.522-529
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2019
M1/M2 polarization of immune cells including microglia has been well characterized. It mediates detrimental or beneficial roles in neuroinflammatory disorders including cerebral ischemia. We have previously found that sphingosine 1-phospate receptor subtype 1 ($S1P_1$) in post-ischemic brain following transient middle cerebral artery occlusion (tMCAO) can trigger microglial activation, leading to brain damage. Although the link between $S1P_1$ and microglial activation as a pathogenesis in cerebral ischemia had been clearly demonstrated, whether the pathogenic role of $S1P_1$ is associated with its regulation of M1/M2 polarization remains unclear. Thus, this study aimed to determine whether $S1P_1$ was associated with regulation of M1/M2 polarization in post-ischemic brain. Suppressing $S1P_1$ activity with its functional antagonist, AUY954 (5 mg/kg, p.o.), attenuated mRNA upregulation of M1 polarization markers in post-ischemic brain at 1 day and 3 days after tMCAO challenge. Similarly, suppressing $S1P_1$ activity with AUY954 administration inhibited M1-polarizatioin-relevant $NF-{\kappa}B$ activation in post-ischemic brain. Particularly, $NF-{\kappa}B$ activation was observed in activated microglia of post-ischemic brain and markedly attenuated by AUY954, indicating that M1 polarization through $S1P_1$ in post-ischemic brain mainly occurred in activated microglia. Suppressing $S1P_1$ activity with AUY954 also increased mRNA expression levels of M2 polarization markers in post-ischemic brain, further indicating that $S1P_1$ could also influence M2 polarization in post-ischemic brain. Finally, suppressing $S1P_1$ activity decreased phosphorylation of M1-relevant ERK1/2, p38, and JNK MAPKs, but increased phosphorylation of M2-relevant Akt, all of which were downstream pathways following $S1P_1$ activation. Overall, these results revealed $S1P_1$-regulated M1/M2 polarization toward brain damage as a pathogenesis of cerebral ischemia.
Reddy, Kondreddy Eswar;Kim, Minji;Kim, Ki Hyun;Ji, Sang Yun;Baek, Youlchang;Chun, Ju Lan;Jung, Hyun Jung;Choe, Changyong;Lee, Hyun Jeong;Kim, Minseok;Lee, Sung Dae
Animal Bioscience
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v.34
no.2
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pp.243-255
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2021
Objective: Deoxynivalenol (DON) and zearalenone (ZEN) are mycotoxins that frequently contaminate maize and grain cereals, imposing risks to the health of both humans and animals and leading to economic losses. The gut microbiome has been shown to help combat the effects of such toxins, with certain microorganisms reported to contribute significantly to the detoxification process. Methods: We examined the cecum contents of three different dietary groups of pigs (control, as well as diets contaminated with 8 mg DON/kg feed or 0.8 mg ZEN/kg feed). Bacterial 16S rRNA gene amplicons were acquired from the cecum contents and evaluated by next-generation sequencing. Results: A total of 2,539,288 sequences were generated with ~500 nucleotide read lengths. Firmicutes, Bacteroidetes, and Proteobacteria were the dominant phyla, occupying more than 96% of all three groups. Lactobacillus, Bacteroides, Megasphaera, and Campylobacter showed potential as biomarkers for each group. Particularly, Lactobacillus and Bacteroides were more abundant in the DON and ZEN groups than in the control. Additionally, 52,414 operational taxonomic units were detected in the three groups; those of Bacteroides, Lactobacillus, Campylobacter, and Prevotella were most dominant and significantly varied between groups. Hence, contamination of feed by DON and ZEN affected the cecum microbiota, while Lactobacillus and Bacteroides were highly abundant and positively influenced the host physiology. Conclusion: Lactobacillus and Bacteroides play key roles in the process of detoxification and improving the immune response. We, therefore, believe that these results may be useful for determining whether disturbances in the intestinal microflora, such as the toxic effects of DON and ZEN, can be treated by modulating the intestinal bacterial flora.
In 2019, about 134 million ㎥ of aggregate was produced in an estimated 880 quarries and pits in 17 metropolitan governments. Leading producing metropolitan cities were Gyeonggi-do, Gyeongsangnam-do, Chungcheongbuk-do, Gangwon-do, Gyeongsangbuk- do, Chungcheongnam-do, in order decreasing volume, which together accounted for about 71% of total product. Of the total domestic aggregates produced in 2019, about 31 % was sand and about 69% was gravel. It estimated that of the 134 million ㎥ of aggregates in Korea in 2019, about 50.3% was produced by screening crushed aggregate by 41.4% by forest aggregate, 3.3% by land aggregate, 1.7% by sea aggregate and 1.7% by washing each other, and 0.7% by river aggregate. This indicates that screening crushed aggregate and forest aggregate are the main producers of domestic aggregates. The most crushed and forest aggregate was extracted at the Gyeonggi-do and Gyeongsangnam-do, respectively. Land aggregate was mainly extracted at Gyeongsangbuk-do and Gangwon-do. Therefore, in the future supply and demand of aggregate resources, it is judged that there should be a primary policy direction for screening crushed and forest aggregate.
The aim of this study is to see how bamboo paintings developed and what is the iconographical meaning of them through bamboo Ti-hua-shi(poems on paintings) found in Sheng-Hua-Ji, a leading compilation of Ti-hua-shi(poems on paintings) of Song Dynasty. Bamboo paintings give shapes in a simpler and more direct way in drawing, which means bamboo paintings reveal concretely more characteristics of Ti-hua-shi (poems on paintings). Bamboo paintings, which flourished during Northern Song Dynasty, often had the image of the dragon, specially a lying dragon or a winding dragon, which suggests a great man in obscurity. Snow-laden bamboos were also a symbol of a great man, very wise man in Confucian tradition. This shows Confucian ideal examples were embodied through bamboo paintings. Another aspect of bamboo paintings is that bamboo paintings were regarded as a means of self-expression, which identified Confucian sadaebu (scholar-officials) who advocated simplicity and austerity in their life. Contrary to professional painters, who added color and decoration to their paintings, Confucian scholars of Song Dynasty reduced color and embellishment in their bamboo paintings in black-and-white to reveal their own identity, focusing on spirituality rather than the image itself. Therefore, drawing and appreciating bamboo paintings were highly respectable pastime among the literati of Song Dynasty. In short, Bamboo paintings in Song Dynasty were not only a Confucian symbol of a wise and virtuous man but also reflected the taste of Song sadaebu class who thought of bamboo as a symbol for moral and cultural responsibility of Confucian society.
This article tries to compare exchange relations between welfare and dictatorship in the East Germany and the North Korea. Unlike capitalist welfare aiming at correcting market results socialist welfare has been proposed to satisfy people's basic needs, but it had operated as instrument of dictatorship. Relation between welfare and dictatorship could be distinguished as hard exchange and soft one in line with social construction of welfare. Welfare-dictatorship relation in East Germany had developed from its formation(1949-1970s), crisis(1980s) and dissolution(1989-1990). There had established hard exchange relation in which the legitimacy of dominance had debted to welfare as social rights. While crisis of the exchange relation had been modest in a form of insufficient supply of consumption goods, it was one of the elements of collapse of dictatorship, leading to the unification with West Germany. The journey of the exchange relation in North Korea can be characterized by its formation(1948-1980), crisis(1990s-2000s), and transformation(2010s). Unlike East Germany, welfare was socially constructed as gift form the ruler to the ruled, which made the combination of welfare and dictatorship loosely coupled. Although economic crisis was severe compared to East German one the rulers have succeeded maintaining dictatorial dominance by creating dual exchange relation. They separated core group and subordinated one supporting the former at the expense of the latter. They blocked out most of the people from soft exchange relation making bad use of muddling-through life style dependent on market activities. This strategy led to a 'dictatorship neutral welfare extinction'. Taking the high degree of institutionalization of newly establishing welfare-dictatorship relation into account, lives of most people are hardly expected to be improved by gift by their rulers even if North Korean economy will recover in the future.
Jang Hyeongwang is one of the leading scholars since the era of Toe'gye and Yulgok in Korean Confucianism. Thus, this paper will summarize his schooling, i.e., education in local school(Hyanggyo), specific activities, and the meaning of moral education. Although Toe'gye and Yulgok recognized the problems of local school and their indictment revealed in 16th century, they sought different solutions to overcome the issues. Toe'gye paid attention to establishment of local academy(Seowon) and strengthening its stature in order to renew Confucian education while Yulgok kept an eye on reformation of local school as government educational institution for revitalizing schooling, fostering the talented and establishing moral discipline. In this context, I will summarize Yeoheon's perspective on schooling in terms of the difference with Toe'gye and Yulgok's ideas. Especially, I will analyze his problematique paying attention to restoration of moral order in local communities devastated since Japanese Invasion of Korea in 1592, and how it makes connection with local education and its implication. Furthermore, I will systematically examine the educational regulation of Indong local school(Indong Hyanggyo) he proposed and what its contents and real body he intended. In addition to these, I will suggest how much Yeohon's ideas on local education are meaningful in moral education and what kind of insightful things they would give us in current educational environments.
In this study, we predicted the bitcoin prices of Bithum and Coinbase, a leading exchange in Korea and USA, using ARIMA and Recurrent Neural Networks(RNNs). And we used news articles from each country to suggest a separated RNN model. The suggested model identifies the datasets based on the changing trend of prices in the training data, and then applies time series prediction technique(RNNs) to create multiple models. Then we used daily news data to create a term-based dictionary for each trend change point. We explored trend change points in the test data using the daily news keyword data of testset and term-based dictionary, and apply a matching model to produce prediction results. With this approach we obtained higher accuracy than the model which predicted price by applying just time series prediction technique. This study presents that the limitations of the time series prediction techniques could be overcome by exploring trend change points using news data and various time series prediction techniques with text mining techniques could be applied to improve the performance of the model in the further research.
We investigated the anti-obesity effect of Gelidium elegans extract (GE) on 3T3-L1 preadipocytes and a high-fat-diet (HFD)-induced mouse model. The results of the present study demonstrated that GE prevents weight gain induced by a high-fat diet (HFD) by modulating the adenosine monophosphate-activated protein kinase (AMPK)-PR domain-containing 16 (PRDM16)-uncoupling protein-1 (UCP-1) pathway in a mice model. Moreover, in vitro results show that GE suppressed adipocyte differentiation by modulating adipogenic regulators, stimulated lipolysis by activating ATGL, and inhibited adipogenesis by downregulating various enzymes associated with triglyceride synthesis. GE was also found to upregulate AMPK phosphorylation as well as the expression of UCP1 and PRDM16 proteins, leading to measurable changes in the beige-like phenotype differentiation of 3T3-L1 cells. Taken together, these findings suggest the role of GE as a functional food ingredient extracted from Gelidium elegans to increase energy expenditure and anti-obesity efficacy.
This numerical study aims at analyzing the effect of flow characteristics, caused by geometrical features such as intersecting angles, on solute mixing at fracture junctions. It showed that not only Pe, the ratio of advection to diffusion, but also the intersecting angles played an important role in solute mixing at the junction. For the intersection angles less than 90°, the fluid flowed to the outlet in the same direction as the injected flow direction, which increased the contact at the junction with the streamlines coming from the different inlets. On the other hand, for the intersecting angles greater than 90°, the fluid flowed out to the outlet opposite to the flow direction in the inlet, leading to minimizing the contact at the junction. Therefore, in the former case, solute mixing occurred even at high Pe, and in the latter case, solutes transport along the streamlines even at low Pe. For Pe < 1, the complete mixing model was known to occur, but for the intersecting angle greater than 150°, no complete solute mixing occurred. Overall, the transition from the complete mixing model to the streamline-routing model occurred for Pe = 0.1 - 100, but it highly depended on the intersecting angles. Specifically, the transition occurred at Pe = 0.1 - 10 for intersecting angles ≧ 150° and at Pe = 10 - 100 for intersecting angles ≦ 30°. For Pe > 100, the streamline-routing model was dominant regardless of intersecting angles. For Pe > 1,000, the complete streamline-routing model appeared only for the intersecting angles greater than 150°. For the intersecting angles less than 150°, the streamline-routing model dominated over the complete solute mixing, but solute mixing still occurred at the fracture junction.
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