• Analytical Science and Technology
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• v.30 no.1
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• pp.10-19
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• 2017

Anabolic steroids have similar structures to testosterone, both of which promote the growth of muscle mass and increase strength. However, the side effects of anabolic steroid use may lead to heart attacks or strokes. Additionally, the excessive use of steroids inhibits the production of the sex hormones in the body via a negative feedback loop, which results in testicular atrophy in males and amenorrhea in females. Currently, the method of choice used to test for the presence of anabolic steroids is GC-MS. However, GC-MS methods require chemical derivatization of the steroid sample to ensure compatibility with the analytical method; therefore, analysis of many different samples is difficult and time consuming. Unlike GC-MS, the liquid chromatography-quadrupole-time of flight mass spectrometry (LC-Q-TOF-MS) method is suitable for many samples. Twenty-two different anabolic steroids were analyzed by LC-Q-TOF-MS with various collision energies (CE). Accurate mass spectral data were obtained using a Q-TOF-MS equipped with an electro-spray ionization source and operated in the positive MS/MS mode for several classes of steroids that are often the targets of testing. Based on the collected data, fragmentation pathways were carefully elucidated. The high selectivity and sensitivity of the LC-Q-TOF-MS instrument combined with these fragmentation pathways offers a new approach for the rapid and accurate screening of anabolic steroids. The obtained data from the 22 different anabolic steroids will be shared with the scientific community in order to establish a library to aid in the screening of illegal anabolic steroids.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.36 no.3
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• pp.167-174
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• 2010

The hair nourisher products are used for prevention of hair loss and classified as quasi-drug in Korea. As concerns about hair loss has been increased, the demand for hair nourisher products has been growing. It is difficult to analyze their main ingredients because they contain various ingredients including natural plant extracts, vitamins, preservatives and exfoliators. The purpose of this study was to develop and validate simultaneous analytical methods of active ingredients in hair nourisher products such as nicotinamide, tocopherol, salicylic acid, dexpanthenol and benzyl nicotinate by HPLC. The active ingredients were separated on a $C_{18}$ column by using acetonitrile/phosphate buffer as a mobile phase, and detected at UV 220, 270 and 300 nm. The calibration curve showed linearity in the range of $12.5{\sim}800\;{\mu}g/mL$ and the recoveries were 97.3 ~ 103.5 % (RSD 0.9 ~ 2.8 %) in liquid matrix and 101.9 ~ 115.9 % (RSD 0.7 ~ 7.7 %) in shampoo matrix. Validated method was applied to hair nourisher products obtained from distribution market. Fortunately, all samples met their criteria. This study might be expected to provide the method for determining active ingredients in hair nourisher products and lead to promote a rapid market entry.

• Journal of the Microelectronics and Packaging Society
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• v.12 no.2 s.35
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• pp.167-174
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• 2005

Smaller size and higher integration of electronic components make smaller gap between metal conducting layers in electronic package. Under harsh environmental conditions (high temperature/humidity), electronic component respond to applied voltages by electrochemically ionization of metal and metal filament formation, which lead to short failure and this phenomenon is termed electrochemical migration(ECM). In this work, printed circuit board(PCB) is used for determination of ECM characteristics. Copper leads of PCB are soldered by eutectic solder alloys. Insulation breakdown time is measured at $85^{\circ}C,\;85{\%}RH$. CAF is the main mechanism of ECM at PCB. Pb is more susceptible to CAF rather than Sn, which corresponds well to the corrosion resistance of solder materials in aqueous environment. Polarization tests in chloride or chloride-free solutions fur pure metal and eutectic solder alloys are performed to understand ECM characteristics. Lifetime results show well defined log-normal distribution which resulted in biased voltage factor(n=2) by voltage scaling. Details on migration mechanism and lifetime statistics will be presented and discussed.

• Korean Journal of Soil Science and Fertilizer
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• v.50 no.5
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• pp.391-400
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• 2017

Italian ryegrass (IRG) is one of the fastest growing grasses available to farmers. It offers rapid establishment and starts growing early in the following spring and has fast regrowth after defoliation. So, IRG can be utilized as the dominant/single species of grass used in a farming system, or to play a role as a large producing pasture and sacrificial paddock. The objective of this study was to develop the use of unmanned aerial vehicle (UAV) for the evaluation of feed value of IRG. For this study, UAV imagery was taken on the Nonsan regions two times during the IRG growing season. We analyzed the relationships between $NDVI_{UAV}$ and feed value parameters such as fresh matter yield, dry matter yield, acid detergent fiber (ADF), neutral detergent fiber (NDF), total digestible nutrient (TDN) and crude protein at the season of harvest. Correlation analysis between $NDVI_{UAV}$ and feed value parameters of IRG revealed that $NDVI_{UAV}$ correlated well with crude protein (r = 0.745), and fresh matter yield (r = 0.655). According to the relationship, the variation of $NDVI_{UAV}$ was significant to interpret feed value parameters of IRG. Eight different regression models such as Linear, Logarithmic, Inverse, Quadratic, Cubic, Power, S, and Exponential model were used to estimate IRG feed value parameters. The S and exponential model provided more accurate results to predict fresh matter yield and crude protein than other models based on coefficient of determination, p- and F-value. The spatial distribution map of feed values in IRG plot was in strong agreement with the field measurements in terms of geographical variation and relative numerical values when $NDVI_{UAV}$ was applied to regression equation. These lead to the result that the characteristics of variations in feed value of IRG according to $NDVI_{UAV}$ were well reflected in the model.

• Journal of the Korean Chemical Society
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• v.55 no.1
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• pp.63-69
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• 2011

This work discusses the fabrication, development and potential response behaviors of $Ag^+$ ion-selective electrodes ($Ag^+$-ISE) based on N,N'-bis(2-hydroxybenzyl)-1,3-diaminopropane (L1) and N,N'-bis(2-hydroxybenzyl)-2,2-dimethyl-1,3-diaminopropane (L2) as carriers. The observations indicated that the resulting electrode based on L1 toward $Ag^+$ showed stable near-Nernst slope approaching 58.7 mV/dec and the optimum potential response characteristics in a linear range at least five orders of magnitude with a detection limit of $1.0{\times}10^{-6}M$. The proposed electrode displayed the preferential selectivity to $Ag^+$ against other tested cations. The excellent potential analytical characteristics could lead to the successful applications of silver assay in significant real samples, indicating that the proposed $Ag^+$-ISE showed a significant advancement of measurement capabilities. But for the electrode based on L2, the poor potential response characteristics were observed in total experiment process.

• Geotechnical Engineering
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• v.13 no.1
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• pp.111-122
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• 1997

The calculation of phase velocities in Spectral-Analysis -of-Surface -Waves (SASW) meas urements requires unwrapping phase angles. In case of layered systems with strong stiffness contrast like a pavement system, conventional phase unwrapping algorithm to add in teger multiples of 2n to the principal value of a phase angle may lead to wrong phase volocities. This is because there is difficulty in counting the number of jumps in the phase spectrum especially at the receiver spacing where the measurements are in the transition Bone of defferent modes. A new phase interpretation scheme, called "Impulse Response Fil traction ( IRF) Technique," is proposed, which is based on the separation of wave groups by the filtration of the impulse response determinded between two receivers. The separation of a wave group is based on the impulse response filtered by using information from Gabor spectrogram, which visualizes the propagation of wave groups at the frequency -time space. The filtered impulse response leads to clear interpretation of phase spectrum, which eliminates difficulty in counting number of jumps in the phase spectrum. Verification of the IRF technique was performed by theoretical simulation of the SASW measurement on a pavement system which complicates wave propagation.opagation.

• Korean Journal of Remote Sensing
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• v.37 no.6_1
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• pp.1517-1526
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• 2021

With the recent global and domestic development of Earth observation satellites, the applications of satellite images have been widened. Research for improving the geometric accuracy of satellite images is being actively carried out. This paper studies the possibility of automated ground control point (GCP) generation for CAS-4 satellite, to be launched in 2025 with the capability of image acquisition at 5 m ground sampling distance (GSD). In particular, this paper focuses to check whether GCP chips with 25 cm GSD established for CAS-1 satellite images can be used for CAS-4 and to check whether optimalspatial resolution for matching between CAS-4 images and GCP chips can be determined to improve matching performance. Experiments were carried out using RapidEye images, which have similar GSD to CAS-4. Original satellite images were upsampled to make satellite images with smaller GSDs. At each GSD level, up-sampled satellite images were matched against GCP chips and precision sensor models were estimated. Results shows that the accuracy of sensor models were improved with images atsmaller GSD compared to the sensor model accuracy established with original images. At 1.25~1.67 m GSD, the accuracy of about 2.4 m was achieved. This finding lead that the possibility of automated GCP extraction and precision ortho-image generation for CAS-4 with improved accuracy.

• Journal of Radiation Protection and Research
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• v.46 no.3
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• pp.127-133
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• 2021

Background: Phosphogypsum is material produced as a byproduct in fertilizer industry and is generally used for building materials. This material may contain enhanced radium-226 (²²⁶Ra) activity concentration compared to its natural concentration that may lead to indoor radon accumulation. Therefore, an accurate measurement method is proposed in this study to determine ²²⁶Ra activity concentration in phosphogypsum sample, considering the potential radon leakage from the sample container. Materials and Methods: The International Atomic Energy Agency (IAEA) phosphogypsum reference material was used as a sample in this study. High-purity germanium (HPGe) gamma spectrometry was used to measure the activity concentration of the ²²⁶Ra decay products, i.e., ²¹⁴Bi and ²¹⁴Pb. Marinelli beakers sealed with three different sealing methods were used as sample containers. Due to the potential leakage of radon from the Marinelli beaker (MB), correction to the activity concentration resulted in gamma spectrometry is needed. Therefore, the leaked fraction of radon escaped from the sample container was calculated and added to the gamma spectrometry measured values. Results and Discussion: Total activity concentration of ²²⁶Ra was determined by summing up the activity concentration from gamma spectrometry measurement and calculated concentration from radon leakage correction method. The results obtained from ²¹⁴Bi peak were 723.4 ± 4.0 Bq·kg^-1 in MB1 and 719.2 ± 3.5 Bq·kg^-1 in MB2 that showed about 5% discrepancy compared to the certified activity. Besides, results obtained from ²¹⁴Pb peak were 741.9 ± 3.6 Bq·kg^-1 in MB1 and 740.1 ± 3.4 Bq·kg^-1 in MB2 that showed about 2% difference compared to the certified activity measurement of ²²⁶Ra concentration activity. Conclusion: The results show that radon leakage correction was calculated with insignificant discrepancy to the certified values and provided improvement to the gamma spectrometry. Therefore, measuring ²²⁶Ra activity concentration in TENORM (technologically enhanced naturally occurring radioactive material) sample using radon leakage correction can be concluded as a convenient and accurate method that can be easily conducted with simple calculation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.574-582
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• 2018

In systems such as railways, automobiles, and airplanes, system malfunctions may lead to accidents, which often cause serious personal injury and economic loss. In previous studies, failure analysis has been performed, and safety measures derived using the component level information to reduce damage when a failure occurs. However, in functional safety concept, a focus is placed on lowering the frequency of occurrence of failures by performing risks analysis, setting up safety goals, and designing safety functions. Therefore, it is necessary to study how to determine the required safety function that can reduce the failure frequency to the acceptable level. To achieve this, we first studied a failure modeling method using SysML. It was then presented how several alternatives can be assessed to determine the desired safety function by simulating the generated SysML failure models and calculating the ability to reduce the failure frequency. A case study of a railway signaling system was done, demonstrating the effectiveness of the approach. We assessed whether the safety objectives were met for the alternative design of the railway signaling system through M & S. The results can be useful in that it can be applied from the early design phase and allow to choose the appropriate safety function that satisfies safety objectives among various design alternatives.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.725-733
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• 2018

With urbanization projects involving trunk roads progressing, many simple interchanges, which separate passing traffic into the main traffic and access subtraffic, are being constructed to maximize the traffic capacity. Under the current Road Connection Rule, the access-prohibited section in an interchange is determined based on the access lane and limit distance in the complete interchange road, but separate criteria for the simple interchange are not defined. This may cause confusion in the Road Management Office's determination of the access-prohibited section in the simple interchange, or lead to the application of the criteria for the access-prohibited section in the complete interchange without considering the features of such interchange. This study conducted a comparative analysis of the domestic and overseas systems related to the installation of access section in trunk roads, such as general national roads. This paper presents a survey of the methods for applying the access-prohibited section in the interchange along with the actual cases and proposes improvement measures for a rational calculation of the access prohibited installation section in the simple interchange to minimize the downsides associated with the application of the extremely strict criteria. The proposed road connection rule improvement measures based on the consideration of the purpose of installing the simple interchange and on the consideration the features of the simple interchange are expected to prevent administration confusion by the field road management offices as well as the waste of unnecessary efforts and costs by petitioners so they can boost the service satisfaction for people and the administrative reliability.