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Surface Topographic Measurement Method for Assessing Lower Extremity Alignment: Examination on a novel clinical and research Tool (하지 정렬 평가를 위한 체표면 토포그래피를 이용한 측정법: 새로운 임상 및 연구 도구에 대한 검토)

  • Yim, Ji-Young;Yim, Hyun-Seung;Park, Dae-Sung;Lee, Na-Kyung;Lee, Na-Kyung
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.10 no.1
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    • pp.37-45
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    • 2016
  • The purpose of this study was to assess the intra-rater, inter-rater and test-retest reliability and validity of frontal plane lower extremity alignment estimated from a rasterstereographic method using ABW-Mapper. Eighteen subjects participated in this study. The S angle (stereographic angle-frontal plane lower extremity alignment estimated from a rasterstereographic method) in standing was measured throughout the two sessions with one week interval by two different readers. In the first session, a reader measured S angle twice per subject with a short break in-between. The Q-angle (quadriceps angle) was measured using a standard goniometer from a photography taken through digital camera with the participant standing in the same position as in the S angle measurement. The HKA(hip-knee-ankle) angle was measured from a computer based digital radiograph with the computerized measurement software. Reliability was tested using intraclass correlation coefficients(ICC). Validity was tested using a Pearson's correlation coefficient. Excellent intra-rater(ICC=0.956~0.974), inter-rater(ICC=0.962), test-retest reliability (ICC=0.945) were demonstrated. There were strong negative correlations between S angle and Q-angle (r=-0.739), and between S angle and HKA angle (r=-0.702). Therefore, the S angle measured using a rasterstereographic mapper may be used to as a preliminary or supplementary tool to evaluate and study LE alignment in the frontal plane in relation to HKA angle or Q-angle.

Maxillary Distraction Osteogenesis Using $TS-MD^{(R)}$ (Trans-sinusoidal Maxillary distractor) on Cleft Patients (Trans-sinusoidal maxillary distractor($TS-MD^{(R)}$)를 이용한 구순구개열 환자에서의 상악골 골신장술)

  • Paeng, Jun-Young;Lee, Il-Gu;Myoung, Hoon;Hwang, Soon-Jung;Seo, Byoung-Moo;Choe, Jin-Yeong;Lee, Jong-Ho;Choung, Pill-Hoon;Kim, Myung-Jin
    • Korean Journal of Cleft Lip And Palate
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    • v.8 no.2
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    • pp.71-79
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    • 2005
  • Purpose: Maxillary hypoplasia is a common developmental problem of cleft lip and palate. Fair results with distraction osteogenesis have been reported especially when these patients need a large amount of maxillary advancement, instead of orthognathic surgery. The purpose of this study is to evaluate the clinical results with a relatively new distractor, $TS-MD^{(R)}$ (Trans-sinusoidal maxillary distractor, KLS Martin, Tuttlingen, Germany) which was used for the advancement of the maxilla in the cleft patients. Patients and Method: Distraction osteogenesis using $TS-MD^{(R)}$ was performed for four CLP patients (three males and one female) who had maxillary hypoplasia. All patients were over 16 years old. As three patients showed mandibular prognathism as well, bilateral sagittal split ramus osteotomy for mandibular setback was performed at the same time. After consolidation periods of 4 to 12 weeks, the distraction devices were removed and miniplates were placed for simultaneous internal fixation. Results: Three patients showed a large amount of incisal overbite but one patient did not have sufficient maxillary advancement. Le Fort I osteotomy, maxillary advancement and internal fixation should have been performed for the patient when removing the distraction devices. Different from the $clinician{\box}s$ expectation, the amount of maxillary advancement using $TS-MD^{(R)}$ was not sufficient, although the device has rigid mechanical property. Rotation of maxilla during distraction forward and downward was also observed. Conclusion: Even though the maxillary advancement with $TS-MD^{(R)}$ device could be achieved, the clinical control of some characteristics related with the device was necessary. More clinical studies on $TS-MD^{(R)}$ should be performed.

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Marker Assisted Selection-Applications and Evaluation for Commercial Poultry Breeding

  • Sodhi, Simrinder Singh;Jeong, Dong Kee;Sharma, Neelesh;Lee, Jun Heon;Kim, Jeong Hyun;Kim, Sung Hoon;Kim, Sung Woo;Oh, Sung Jong
    • Korean Journal of Poultry Science
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    • v.40 no.3
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    • pp.223-234
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    • 2013
  • Poultry industry is abounding day by day as it engrosses less cost of investment per bird as compared to large animals. Poultry have the most copious genomic tool box amongst domestic animals for the detection of quantitative trait loci (QTL) and marker assisted selection (MAS). Use of multiple markers and least square techniques for mapping of QTL affecting quality and production traits in poultry is in vogue. Examples of genetic tests that are available to or used in industry programs are documented and classified into causative mutations (direct markers), linked markers in population-wide linkage disequilibrium (LD) with the QTL (LD markers), and linked markers in population wide equilibrium with the QTL (LE markers). Development of genome-wide SNP assays, role of 42 K, 60 K (Illumina) and 600 K (Affymetrix$^{(R)}$ Axim$^{(R)}$) SNP chip with next generation sequencing for identification of single nucleotide polymorphism (SNP) has been documented. Hybridization based, PCR based, DNA chip and sequencing based are the major segments of DNA markers which help in conducting of MAS in poultry. Economic index-marker assisted selection (EI-MAS) provides platform for simultaneous selection for production traits while giving due weightage to their marginal economic values by calculating predicted breeding value, using information on DNA markers which are normally associated with relevant QTL. Understanding of linkage equilibrium, linkage dis-equilibrium, relation between the markers and gene of interest are quite important for success of MAS. This kind of selection is the most useful tool in enhancing disease resistance by identifying candidate genes to improve the immune response. The application of marker assisted selection in selection procedures would help in improvement of economic traits in poultry.

A Modeling of Web-service for Construction CALS/EC Standard Guideline by using Component Based Development (컴포넌트 기반 개발방법론에 의한 건설 CALS/EC 표준지침 웹서비스의 모델링)

  • 이상호;정용환;김소운
    • Proceedings of the CALSEC Conference
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    • 2003.09a
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    • pp.78-83
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    • 2003
  • 본 연구에서는 건설CALS/EC 기반의 정보화 추진을 위한 정보시스템을 개발할 때 적용되는 기존의 소프트웨어 개발방법론의 문제점을 분석하고, 표준화되지 않은 개발방법론의 적용으로 시스템 개발에 비효율적인 비용을 투자하는 문제점과 특성상 입찰, 구매, 계약 등 분야별로 상이한 기능의 업무에 따라 구축되는 건설산업 정보화에 있어서 상호간에 데이터 및 프로세스를 원활히 통합하지 못하므로 인하여 발생되는 개발의 중복성, 정보 활용의 비효율성 등의 문제점을 개선하고자 하였다. 이를 위하여 최근 새로이 부각되고 있는 방법론인 컴포넌트 기반 개발방법론(CBD: Component-Based Development)을 사용하여 건선CALS/EC 표준지침 웹서비스를 위한 시스템의 업무프로세스를 모델링하여 사용자가 쉽게 재사용가능하고 타업무분야에 확대 가능한 방향을 제시하였다. 본 연구를 위하여 기존의 소프트웨어 개발 방법론의 적용상 문제점 분석을 통하여 컴포넌트 기반 개발방법론의 필요성을 증명하고 비즈니스 컴포넌트 프레임워크를 사용하여 건설 CALS/EC 표준지침 웹서비스의 업무프로세스에 적용할 기술적인 방법론을 고찰하고 업무에 효과적으로 적용할 수 있는 업무프로세스 컴포넌트를 제시하였다. 본 연구에서 도출된 컴포넌트 모델은 향후 타업무분야의 시스템을 개발할 때 사용자요구분석 단계부터 별도의 재 작업이 없이 사용될 수 있으며 시스템을 구현할 때 개발 모듈의 중복방지와 용이한 비즈니스로직의 변경 등이 가능하며, 추가의 업무 프로세스나 연관된 다른 분야의 업무프로세스의 반영 및 추가 시 컴포넌트의 활동모델을 쉽게 수정하여 정의함으로써 쉽게 시스템의 기능을 확장할 수 있다.LE 산정에 관한 지속적인 실험적 연구가 이루어져야 하겠다. 증가할 것이다. 또한 부분육을 이용한 완전제품, 적색육제품, 유기농이나 별미식 제품과 같은 형태의 다양한 포장육 제품이 도입 될 것으로 생각되어진다.e in vitro SPF test method will be able to be used as an alternative method for in vivo SPF in case of lotion and cream. replica. A statistically significant improvement of Star Fruit Leaf Extract BG30-treated site was seen in decreased wrinkles. Star Fruit Leaf Extract BG30 results in clinically visible improvement in wrinkling when used topically for 5 weeks. 또한 관계마케팅, CRM 등의 이론적 배경이 되고 있는 신뢰와 결속의 중요성이 재확인하는 결과도 의의라고 할 수 있다. 그리고 신뢰는 양사 간의 상호관계에서 조성될 수 있는 특성을 가진 반면, 결속은 계약관계 초기단계에서 성문화하고 규정화 할 수 있는 변수의 성격이 강하다고 할 수가 있다. 본 연구는 복잡한 기업간 관계를 지나치게 협력적 측면에서만 규명했기 때문에 많은 측면을 간과할 가능성이 있다. 또한 방법론적으로 일방향의 시각만을 고려했고, 횡단적 조사를 통하고 국내의 한 서비스제공업체와 관련이 있는 컨텐츠 공급파트너만의 시각을 검증했기 때문에 해석에서 유의할 필요가 있다. 또한 타당성확보 노력을 기하였지만 측정도구

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Cloning of a Novel vpr Gene Encoding a Minor Fibrinolytic Enzyme from Bacillus subtilis SJ4 and the Properties of Vpr

  • Yao, Zhuang;Meng, Yu;Le, Huong Giang;Lee, Se Jin;Jeon, Hye Sung;Yoo, Ji Yeon;Kim, Hyun-Jin;Kim, Jeong Hwan
    • Journal of Microbiology and Biotechnology
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    • v.30 no.11
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    • pp.1720-1728
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    • 2020
  • We have previously characterized AprESJ4, the major fibrinolytic enzyme from Bacillus subtilis SJ4 (Yao et al., 2019). During that study, we observed a 68 kDa protein with fibrinolytic activity. In this study, we cloned the gene (vprSJ4) encoding the 68 kDa protein, a mature Vpr and minor protease secreted by Bacillus species. vprSJ4 encodes a preproenzyme consisting of 810 amino acids (aa) including signal sequence (28 aa) and prosequence (132 aa). The mature enzyme (650 aa) has a predicted molecular weight of 68,467.35. Unlike Vprs from other B. subtilis strains, VprSJ4 has 4 additional amino acids (DEFA) at the C-terminus. vprSJ4 was overexpressed in Escherichia coli. PreproVprSJ4 was localized in inclusion bodies, and subjected to in vitro renaturation and purification by an affinity column. SDS-PAGE and western blot showed that autoprocessing of preproVprSJ4 occurred and 68 kDa and smaller proteins were produced. The optimum pH and temperature of the recombinant VprSJ4 were pH 7.0 and 40℃, respectively. Kinetic parameters of recombinant VprSJ4 were measured by using an artificial substrate, N-succinyl-ala-ala-pro-phe-p-nitroanilide. Coexpression of vprSJ4 and aprESJ4 using pHY300PLK increased the fibrinolytic activity a further 117% when compared with aprESJ4 single expression using the same vector in B. subtilis WB600.

Development of Jeju Local Food Tour Package and Economic Value Estimation based on Contingent Valuation Method (제주 향토음식을 활용한 음식관광상품 개발 및 CVM을 적용한 경제적 가치 평가)

  • Ahn, So-jung;Yoon, Ji-young
    • Journal of the East Asian Society of Dietary Life
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    • v.26 no.4
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    • pp.346-358
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    • 2016
  • Local food reflects the identity and image of a specific region. It is also a core element for determining tourists' experience of a region. The purpose of the present study was to develop a Jeju food tour package using local foods and estimate the economic value of the suggested tour package using Contingent Valuation Method (CVM). Five food tour packages were developed by researchers. In order to modify and measure the value of each package, an expert panel survey was conducted, and 'package 5' was selected as a food tour scenario for the tourist survey. A survey was conducted on 295 domestic tourists who visited Jeju within the past 10 years in order to evaluate the economic value and feasibility of the Jeju food tour package. A total fo 72.9% of respondents answered that they were willing to pay for the Jeju local food tour, and the willingness to pay (WTP) range was between ₩45,000 and ₩105,000. The primary factors correlated with WTP was food expenses, followed by leisure experience expenses, interest in local foods, education level, visit frequency and age. The WTP of the Jeju local food tour was calculated with the significantly affected factors using stepwise regression model. The result of the present study reveal that tourists' WTP increased with higher food expenses, education level, and age group. The average value of food expenses, education level, and age were substituted into the formula derived from the regression analysis, yielding 58,385.752 KRW as the WTP. The expected economic value created by exploiting the Jeju local food tour was shown to be 700 billion KRW per year, calculated by multiplying WTP of the food tour packages by the number of tourists. This study examined the feasibility and plan of the food tour package to increase the economic value of Jeju local food. In the case of the culinary tour program based on Jeju local food launching, the estimated economic effect was great. Therefore, in-depth research to merchandise the Jeju local food tour program is needed.

The Effects of Ward Exercise Program on the Improvement of Activity of Daily Living in Patients Who have Stroke (뇌졸중환자의 일상생활동작 증진을 위한 침상운동 프로그램의 효과)

  • Sok So-Hyune;Kang Hyun-Sook
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.2 no.1
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    • pp.87-101
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    • 1995
  • This study was conducted with the subject of showing the importance of early rehabilitation and exercise therapy in patients who have stroke, of confirming the adavntage of ward exercise conducted by nurse, which had been conducted mainly by physical therapist only in physical thrapy room and of developing the exercise program as the independent rehabilitation nursing intervention. A total of 62 patients were selected as object from April, 5th, to May, 17th, 1995, who had been hospitalized in K medical center, and the half of them were assigned to Experimental group in ramdom assignment using a coin. It was ADL check list tool developed by Kang and Ward Exercise Program developed by the researcher that were used as a treatment. Ward Exercise Program was conducted by the reseacher and the physical therapist measured ADL score before and after Ward Exercise Program. The data were analyzed using ANOVA, pearson correlation, Chi-Square test and the effect of Ward Exercise Program was analyzed by t-tast. The result of this study is as follows. 1. The experimental group showed eminent improvement of ADL compared with the counter group with statistical significance. In eating(t=6.10, df=60, p=.000), personal hygiene performing(t=4.86, df=60, p=.000), wearing(t=5.86, df=60, p=.000), elimination(t=7.89, df=60, p=.000), mobility on the bed(t=13.36, df=60, p=.000), moving(t=9.11, df=60, p=.000), walking(t=7.45, df=60, p=.000) 2. There was no qualitative difference between experimental group and control group with the significance of $p{\le}.05$. 3. There was no relation between the general condition and the difference of ADL, while there was significant relation between the starting point of exercise and the difference of pre-exercise and post exercise ADL. As a result, it should be emphasized that the early rehabilitation and exercise therapy are important in patients who have stroke, and that it is necessary to extend the exercise therapy to the ward. Therefore, this Ward Exercise Program could be recommended as a independent clinical exercise nursing intervention in rehabilitation nursing of patients who have stroke.

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LED-to-LED Two Way Visible Light Communication System (LED-to-LED 양방향 가시광통신 시스템)

  • Jo, Seung Wan;Oh, Hoon;Lee, Yeon Jae;Le, The Dung;An, Beongku
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.1
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    • pp.79-85
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    • 2016
  • Recently, visible light communication(VLC) is being actively researched as green wireless communication services are drawing attention. Currently, VLC mostly uses LED for transmission and PD(Photo Diode) for receiving. However, this kind of system has limited applications. Therefore, we design and propose in this paper, a LED-to-LED two way VLC system that doesn't use PD(Photo Diode). This system has the following features and contributions. First, this system uses just LED at both transmitter and receiver with analog switch, Second, this system support both one-way communication and two way communication together. One way communication can support multi-hop communication. The performance evaluation of the proposed system is conducted at a place with standard light. We test the success or failure of one way communication by changing distance and baud rate while test the success and failure of two way communication by changing distance. We expect that the proposed LED-to-LED system in this paper can be applied for various application fields.

IGRINS First Light Instrumental Performance

  • Park, Chan;Yuk, In-Soo;Chun, Moo-Young;Pak, Soojong;Kim, Kang-Min;Pavel, Michael;Lee, Hanshin;Oh, Heeyoung;Jeong, Ueejeong;Sim, Chae Kyung;Lee, Hye-In;Le, Huynh Anh Nguyen;Strubhar, Joseph;Gully-Santiago, Michael;Oh, Jae Sok;Cha, Sang-Mok;Moon, Bongkon;Park, Kwijong;Brooks, Cynthia;Ko, Kyeongyeon;Han, Jeong-Yeol;Nah, Jakyuong;Hill, Peter C.;Lee, Sungho;Barnes, Stuart;Park, Byeong-Gon;T., Daniel
    • The Bulletin of The Korean Astronomical Society
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    • v.39 no.1
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    • pp.52.2-52.2
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    • 2014
  • The Immersion Grating Infrared Spectrometer (IGRINS) is an unprecedentedly minimized infrared cross-dispersed echelle spectrograph with a high-resolution and high-sensitivity optical performance. A silicon immersion grating features the instrument for the first time in this field. IGRINS will cover the entire portion of the wavelength range between 1.45 and $2.45{\mu}m$ accessible from the ground in a single exposure with spectral resolution of 40,000. Individual volume phase holographic (VPH) gratings serve as cross-dispersing elements for separate spectrograph arms covering the H and K bands. On the 2.7m Harlan J. Smith telescope at the McDonald Observatory, the slit size is $1^{\prime\prime}{\times}15^{\prime\prime}$. IGRINS has a $0.27^{\prime\prime}$ pixel-1 plate scale on a $2048{\times}2048$ pixel Teledyne Scientific & Imaging HAWAII-2RG detector with SIDECAR ASIC cryogenic controller. The instrument includes four subsystems; a calibration unit, an input relay optics module, a slit-viewing camera, and nearly identical H and K spectrograph modules. The use of a silicon immersion grating and a compact white pupil design allows the spectrograph collimated beam size to be 25mm, which permits the entire cryogenic system to be contained in a moderately sized rectangular vacuum chamber. The fabrication and assembly of the optical and mechanical hardware components were completed in 2013. In this presentation, we describe the major design characteristics of the instrument and the early performance estimated from the first light commissioning at the McDonald Observatory.

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Flocculation Kinetics Using Fe(III) Coagulant in Advanced Water Treatment: The Effect of Sulfate Ion (상수처리시 Fe(III) 응집제를 이용한 응집동력학에 관한 연구 : 황산이온의 영향)

  • 강임석;이병헌
    • Journal of Environmental Science International
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    • v.4 no.4
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    • pp.367-377
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    • 1995
  • The study of flocculation kinetics is of fundamental interest in the field of water treatment, because rational study of the factors affecting the coagulation process should be based on the rate of particle growth. The effect of sulfate on flocculation kinetics were examined using ferric nitrate as a coagulant to coagulate kaolin clay in water under several experimental conditions. Both the particle size distribution data obtained from the AIA and the on-line measurement of turbidity fluctuation by the PDA were used to measure flocculation kinetics. Results show that sulfate ion added to the kaolin suspension played an important role in the flocculation process, not only improving flocculation kinetics at more acidic pH levels but also changing surface charge of particles. The kinetics of flocculation were improved mainly by the enhanced rate and extent of Fe(III) precipitation attributed to the addition of sulfate, and thereby, better interparticle collision frequency, but little by the charge reductions resulting from the sulfate addition. The increase in sulfate concentration beyond $3\times10^{-4}M (up to 2\times10^{-3}M)$ did not induce further improvement in flocculation kinetics, although the higher concentrations of sulfate ion substantially increased the negative ZP value of particles. Key Words : Flocculation Kinetics, Fe(III) Coagulant, Sulfate ion, Turbidity Fluctuation.

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