• 성인간호학회지
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• 제20권4호
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• pp.664-673
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• 2008

Purpose: The purpose of this study was to identify the effect of meridian acupressure on constipation in bed-ridden aged inpatients. Methods: The research design was a non-synchronized non-equivalent control group pretest-posttest design. The subjects consisted of 28 bed-ridden aged inpatients. Meridian acupressure was administered to the experimental group at 30 minutes before breakfast every morning for two weeks. Each meridian was pressured for 10 seconds, 10 times. The frequency of defecation and stool form were examined every day. The data was analyzed by the $x^2$-test, Fisher's exact test, t-test and repeated measures ANOVA. Results: The experimental group given Meridian Acupressure had a higher frequency of defecation(F = 59.372, p = .000) and normal stool(F = 46.046, p = .000) than the control group. Conclusion: The results suggest that Meridian Acupressure was an effective method for the relief of constipation for bed-ridden aged inpatients. A follow -up research is needed to validate that other patients with constipation can use the Meridian Acupressure as a non-invasive nursing intervention instead of a laxative or enema.

• 대한임상독성학회지
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• 제3권1호
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• pp.48-51
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• 2005

Diagostic imaging can help in management of toxicologic emergencies. We report a patient who presented to the emergency department with coma and suppressed respiration after ingestion of unknown substance. We documented chloroform with radiopaque material in bowel on abdominal radiograph. We used activated charcoal and laxative to decontaminate bowel. Hepatotoxicity occurred on 3rd admission day and elevation of liver enzyme reached peak level on 5th admission day. The patient received hemoperfusion, N-acetylsystein and supportive cares. The patient was improved from hepatic dysfunction and discharged without complication on 11th admission day. Radiograph in toxicology may confirm a diagnosis and assist in therapeutic intervention.

• Journal of Nutrition and Health
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• 제32권1호
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• pp.40-49
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• 1999

This study was conducted with 20 female gymnasts and 23 age-matched controls to examine pattern, weight control behavior and nutritional status. Most gymnasts(95.0%) reported that they used weight-control methods, while relatively few age-matched controls employed these methods. These methods included sauna(95.0%), food restriction(90.0%), excess exercise (70.0%), laxative abuse(10%) and use of diet pills(10%). Gymnasts had significantly (p<0.05) lower scores for statements related to 'sneaking food', 'vomiting after overeating', showing more negative eating behavior than age-matched controls. Energy intake of gymnasts was 968.9$\pm$421.4kcal while energy expenditure was 2,091$\pm$361kcal, showing negative evergy balance(-1,1225$\pm$534.6kcal). Female gymnasts consumed less than 70% of the RDA for protein, calcium, iron, vitamin A, thiamin, riboflavin and niacin, which reflects their low energy intake. The average intakes of calcium, iron, vitamin A, thiamin, riboflavin and niacin did not meet the recommended dietary allowances for their age groups. Adolescent athletes who train vigorously and consume a low-energy diet may be exposed to an increase in potential health risks. Therefore, individuals who advise athletic adolescents regarding training and dietary habits need to emphasize the importance of consuming an appropriate energy intake to support performance as well as growth and development. The sports nutritionist is in a position to convey such information to coaches, physicians, parents and to the athletes themselves.

• Nutrition Research and Practice
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• 제6권4호
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• pp.334-339
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• 2012

This study was conducted to compare body shape satisfaction, body image perception, weight control status, and dietary habits of Korean and Chinese female high school students in order to provide information for proper body image perception of adolescents. 221 students in Yongin, a city in Korea, and 227 students in Weihai, a city in China, were surveyed using questionnaires. Body shape satisfaction was significantly higher in Chinese students (P < 0.001) compared to Korean students. 76.2% of Korean students and 72.7% of Chinese students wanted a thinner body shape than their present body shapes. Experiences of weight control, laxative or diuretics uses, eating during weight control, and vomiting after eating were significantly higher in Korean students (P < 0.05-P < 0.001) compared to Chinese students. The score for dietary habits was significantly higher in Chinese students (P < 0.001) compared to Korean students, suggesting a more desirable dietary habit among Chinese students. Students of both countries showed a significantly positive correlation between body shape satisfaction and dietary habits, suggesting that as body shape satisfaction increases, dietary habits become more desirable. In conclusion, Korean female students showed a more distorted body image perception and had more poor dietary habits than Chinese students. Nutritional education for the establishment of normal body weight, proper body image perception, and healthy dietary habits are needed.

• 한국식품영양과학회지
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• 제25권3호
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• pp.539-549
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• 1996

Large bowel cancer correlates tightly to dietary factors such as dietary fiber and fat. Dietary fiber prevents the large bowel cancer in different modes of action which depend upon physicochemical and fermentable properties. Water-soluble fiber is fermented easily by intestinal microbes producing short chain fatty acids ; in contrast, water-insoluble fiber occurs effectively more rapid transit time due to greater bulk of gut content, though it is unfermentable. Not only short chain fatty acid is utilized in the proximal and distal colon as primary energy source, but also it lowers pH in the colon to normalize cellular differentiation and helps to stimulate peri staltic movement by acting as an osmotic laxative. In particular, butyric acid may also regulate gene expression and cell growth, though it is an important respiratory fuel for the colonocyte. Since dietary fiber and non-digestible oligosaccharides are the major source of butyric acid, this provides a possible link between dietary fiber and oligosaccharide and prevention of large bowel cancer. But, as with many links between dietary fiber and large bowel cancer, a direct casual association has not been established. In addition, RDA of dietary fiber which is 20~25g/day for adult Japanese, appears to be reasonable for the defecation once daily and the prevention of large bowel cancer.

• 생약학회지
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• 제13권4호
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• pp.145-152
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• 1982

Three species of genus Polygonum, namely P. cuspidatum, P. sachalinense and P. ellipticum are distributed in Korea. Polygonum ellipticum Migo is a perennial herb in Polygonaceous plants. The root of the plant (Polygoni Rhizoma, 'Ho-jang') have been used as laxative, diuretic and for the treatment suppurative dermatitis in the oriental medicine. As the part of the study for the comparison of the three species in their components, the authors attempted to isolate the anthraquinones and stilbene derivative from the rhizome of P. ellipticum. The methanolic extract of dried rhizome of this plant was fractionated into ether soluble and insoluble fraction and each fraction was applied to column chromatography to isolate above mentioned components. Anthraquinone derivatives were isolated first; comp. I, mp $204{\sim}205^{\circ}$ (physcion), comp. II, mp $254{\sim}255^{\circ}$ (emodin), comp. IV, mp $191{\sim}192^{\circ}$ $(emodin-8-O-{\beta}-D-glucoside)$ and comp. III, mp $280{\sim}282^{\circ}$ $({\beta}-sitosterol-glucoside)$. They were identified by chemical properties and UV, IR and NMR spectra and by the direct comparison with authentic samples. Stilbene derivative was isolated secondly; comp. V, mp $255{\sim}256^{\circ}$ which was reported to possess antibacterial and antifungal activities.

• 임산에너지
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• 제22권3호
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• pp.37-42
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• 2003

붉은싸리버섯(Ramaria formosa(Fr.) Quel)의 독성 또는 하제성분을 분석키 위하여 시료를 메탄올로 3회 반복 추출한 후 2회 필터링하여 분석 시료로 하였으며 GC와 GC-MS를 이용하여 Libraries Search 방법으로 그 성분을 분석하였다. 그 결과, (1) methyl-hexadecanoate, (2) methyl-9,12-octadecadienoate, (3) methyl-cis-9-octa decenoate, (4) methyl-octadecanoate, (5) 4-hexyl-2,5-dihydro-2,5-dioxo-3-furanacetic acid 등 다섯 가지의 화합물이 분석 되었으며, 다량성분인 (5)번째 화합물은 하제유발물질이라 생각되며, 앞으로 동물실험을 통하여 변비나 하제물질에 대한 건강식품이나 하제약품개발을 기대할 수 있을 것이다.

• 약학회지
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• 제57권6호
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• pp.406-411
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• 2013

Rumex crispus (Curled Dock, Polygonaceae) is a perennial wild plant used in traditional medicine as a laxative, astringent, and to treat blood and skin disease. The ethanol extract of R. crispus was obtained and its carbohydrate contents were analyzed using high-performance anion-exchange chromatography with pulsed amperometric detection. The anabolic effects of R. crispus in human osteoblastic MG-63 cells were investigated using the WST-8 assay, alkalinephosphatase (ALP) assay, and mineralization assay. The ethanol extract increased the proliferation of MG-63 cells and stimulated ALP activity in a dose-dependent manner over a 72-hrs period. Additionally, the ethanol extract dose-dependently stimulated the formation of bone nodules in MG-63 cells treated for 12 days. The ethyl acetate fraction from the ethanol extract did not affect osteoblast viability but induced an increase in ALP activity. In conclusion, the ethanol extract of R. crispus increases the proliferation and bone-forming activity of osteoblasts, and hence it could be used in the development of bone-forming stimulatory nutraceuticals and osteoporosis-related medicines.

• 셀메드
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• 제12권2호
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• pp.7.1-7.8
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• 2022

The Unani System of Medicine (USM) is one of the traditional systems of medicine that deals with plants. Plants are large source of medicine. JIRJEER (Eruca sativa) is one of the plant origin drugs, has been used for various therapeutic purposes in USM. It contains Erucic acid (major contain), oleic acid, linoleic acid, saturated Fatty acids, Flavonoids, Phenolics, Glucosinolate, Vitamin C and Carotenoids. These active constituents are responsible for their actions described in Unani classical literature such as Muqqawwi-e-bah (Aphrodisiac), Muwallid-e-mani (Spermatomatogenic), Daf-e-sumoom (Antidote), Kasir-e-riyah (Carminative), Jaali (Cleanser/Detergent), Mudirr-e-bawl (Diuretic) wo Mudirr-e-hayd (Emmenogoggue), Muhammir (Rubefacient), Hazim (Digestive), Mulaiyan (Laxative), Muzliq-e-mani (Lubricant), Muddir-e-shir (Galactopoietic), Mufattih-e-Sudad (Deobstruent), Musakhin (Analgesic), Mulattif (Demulcent), Mufattit-i-hasah (Lithotriptic) and whole plant is considered as aphrodisiac. This is a review paper which discusses morphology, pharmacological action, ethno-medicinal and therapeutic uses of this medicinal plant in perspective of Unani medicine. This review has been done through online searches of databases such as PubMed, Google Scholar, Embase, science direct and hand search for classical textbook available in different libraries. It concluded that JIRJEER (Eruca sativa) is one of the best herbal medicines in treatment of Antiulcer, Antibacterial, Fertility, Hepato-protective, Hyperlipidemic, Antioxidant, Antihypertensive, Anti-inflammatory and Anti-edema, Nephro-protective, Antidiabetic, Antifungal and Anticancer properties.

• Journal of Nutrition and Health
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• 제33권6호
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• pp.675-683
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• 2000

The purpose of this study was to find out the prevalence of constipation nutrition knowledge on dietary fiber and frequency of dietary fiber foods intake of 3rd grade high school girls in Kangnung and Seoul. The total 412 questionnaires were analyzed. Defecation frequency was irregular in 47.6% of the students 21.6% had less than twice a week. Those who were in a hurry during defecation frequency was irregular in 47.6% of the students 21.6% had less than twice a week. Those who were in a hurry during defecation were 57.9% and those spent more than 10 min. for defecation were 21.8% More than half of the students(56.6%) answered to have constipation and 13.8% had taken laxative pills more than once during the last one month period. The nutrition knowledge score was relatively high 7.63 points out of possible 10. Dietary fiber intake scores measured by food frequency questionnaire were 3.78 for fruits 3.71 points out of possible 10. Dietary fiber food intake scores measured by food frequency questionnaire were 3.78 for fruits 3.71 for vegetables and 3.37 for seaweeds meaning taken once a week to 2-3 times per month. For the diagnosis of defecation difficulty a factor called "constipation index" was introduced which was composed of defecation frequency time spending for defecation easiness in defecation and feeling of residue in the intestine after defecation. The Cronbach a coefficient of constipation index was 71. Constipation index was significantly correlated with stress level(p<0.05) haste during defecation(p<.01) and defecation time(p<.01) The higher the stress level the more hurry during defecation and the later the defecation the higher the constipation index. The students who ate more often vegetables and seaweeds had lower constipation index(p<.05, p<.01)05, p<.01)