• 한국의류산업학회지
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• 제8권4호
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• pp.471-475
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• 2006

Rose와 Lavender essential oil의 계면활성제 유발피부염증에 대한 유효성 연구결과는 다음과 같다. 단백질 분석결과 Rose essential oil 과 Lavender essential oil 이 피부에 자극은 있지만, 단백질의 과도한 변성을 한다는 것은 거의 없다. 단 43Kd 범위이하 해당되는 단백질의 밴드 변화에 있어서는 대조군의 Rose essential oil 처리군과 Lavender essential oil 처리군 에서만 나타났다. 표피층 관찰결과에서 손상된 처리군은 과각질이 일어났으며 각질층이 상당히 비후된 상태로 나타났고, 3주동안 Rose essential oil 처리군에서는 표피구조가 정상적인 표피 구조로 회복되어 가고 있는 것을 볼 수 있었으며, 반면에 손상군의 Lavender essential oil 처리군에서는 과각화 되었던 박리층이 떨어져 나감을 볼 수 있었다. 기저층의 변화를 관찰한 결과 대조군에서는 Rose essential oil 처리군과 Lavender essential oil 처리군에서 모두 일정한 세포층을 이루었으며, 손상군에서는 Lavender보다 Rose essential oil 처리군이 정상적인구조의 기저층이 발생됨을 확인할 수 있었다. Mast cell 실험에서 보면 손상된 처리군에서 Mast cell의 숫자의 변화는 Lavender essential oil 처리군이 Mast cell의 수가 많아짐을 알 수 있고 손상군에서 보다 세포의 크기가 커지고 수도 많아짐을 알 수 있었다.

• Environmental Analysis Health and Toxicology
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• 제23권4호
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• pp.315-323
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• 2008

In this study, the backs with a hair cut of 6-week-old healthy ICR male mice were once exposed to a dose of $400\;mJ/cm^2$ UVB. An acute dermal inflammation was observed, and the certified 100% pure and natural lavender essential oil were applied to the UVB-exposed mice skin twice a day. It was observed that the mice exposed to UVB resulted in an acute inflammation, and when treated with lavender oil the degree of inflammation was much alleviated, and the inflamed skins of both the control and lavender oil-treatment groups were cured almost completely after 6 days of the UVB exposure. At 24 hours after UVB exposure, the epidermal keratinocytes in the control group showed a cell-membrane damage with the destruction of intercellular junctions, agglutination of tonofilaments within the cytoplasm and nucleus damage, while the lavender oil-treatment group had much less cell damage than the control group. While the control group showed a significant increase (p<0.05) in the activity of XO up to 144 hours, the lavender oil-treatment group did not show any significant increase except for 48 hours after the UVB exposure. Both the control and lavender essential oil-treatment groups had a significant decrease in the activities of CAT and SOD up to 96 hours. Particularly, the CAT activity was significantly lower(p<0.05) in the lavender oil-treatment group than the control group up to 48 hours, and higher than the control group at and after 96 hours. The GST activity was significantly decreased in both the control and lavender oil-treatment groups up to 96 hours after the UVB exposure except for the control group at 24 hours, and that of the lavender oil-treatment group was higher than the control group at and after 96 hours. Therefore, it is assumed that the application of the lavender oil to the ultraviolet-damaged mice skin can be effective in treatment for the damaged skin.

• 동의신경정신과학회지
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• 제19권1호
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• pp.19-28
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• 2008

Objectives : This study is designed to evaluate the preferences for cypress, rosemary, and lavender essential oil related to Sasang constitution Methods : 79 patients and 70 students were tested by QCSS II and their preferences for cypress, rosemary, and lavender essential oil were investigated . It is analyzed by relationship between Sasang constitution and preference for essential oil. Results: 1. The number of Taeyangin was 3, Taeumin was 20, Soyangin was 6, Soeumin was 50 in patients group and all Taeyangins prefered cypress essential oil, 50% of 20 Taeumins prefered cypress, 45.0% prefered rosemary, and the rest prefered lavender oil. Soyangins prefered cypress, rosemary, lavender oil with the same ratio. 34.0% of 50 Soeumins prefered cypress, 44.0% prefered rosemary, 22.0% prefered lavender oil. 2. The number of Taeyangin was 2, Taeumin was 13, Soyangin was 18, Soeumin was 37 in 70 students group and one of Taeyangin prefered rosemary, and the rest prefered lavender oil. 15.4% of 13 Taeumins prefered cypress, 38.5% prefered rosemary, 46.2% prefered lavender oil. 38.9% of 18 Soyangins prefered cypress, 33.3% prefered rosemary, 27.8% prefered lavender oil. 35.1% of 37 Soeumins prefered cypres, 35.1% prefered rosemary, 29.7% prefered lavender oil. Conclusion : We don't have any significant differences of the preference for essential oil between Sasang constitution.

• 대한간호학회지
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• 제31권5호
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• pp.770-780
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• 2001

This quasi-experimental study was to explore the effects of back massage with Lavender essence oil on the stress response of the ICU nurses. Method: Twenty nurses were selected as an experimental group and twenty nurses were in the control group. Lavender essence oil mixed with Jojova carrier oil was used to massage the neck, shoulder, back, and low back. Massage was done three times a week for 20 minutes for 2 weeks by the massage therapist. The stress response was measured with a subjective stress score, Cortisol and IgA level in saliva. The cortisol level in saliva was analyzed by an radioimmunoassay before and after back massage. The level of IgA in saliva was analyzed by an immunoturbidimeter assay and subjective stress scores was measured by Visual Analogue Scale. The data was analyzed using SPSS 8.0 and the hypotheses were tested by ANCOVA and the Pearson coefficient correlation. Result: 1) Score of subjective stress decreased significantly after the use of back massage with Lavender essence oil. 2) Level of Cortisol in saliva did not change significantly after the use of back massage with Lavender essence oil. 3) Level of IgA in saliva increased significantly after the use of back massage with Lavender essence oil. 4) After the use of back massage with Lavender essence oil, there was significant negative correlation between subjective stress and level of IgA in saliva. Conclusion: Back massage with Lavender essence oil is an effective intervention to reduce the stress response in the ICU nurses.

• 한국패션뷰티학회지
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• 제3권3호
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• pp.48-55
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• 2005

The summary of a study of efficacy of Rose essential oil and Lavender essential oil against physiologic active change s of skin caused to surfactant is as follows. 1. In feed intake efficiency, there is more significant difference than control group, and then in water intake, there are significant differences between each group. It is presented that the water intake efficiency ratio of the group treated by Rose essential oil and Lavender essential oil is higher than all of groups to be participated in experiment. And then, the reason that the group treated Lavender essential oil is lower than any other group is needed water intake to be caused by stress. 2. As the result of serum analysis, in atherosclerotic index(A.I), the cholesterol of control group is higher than that of the group treated. As HDL cholesterol is activated, the dan1aged group is higher than control group, in LDL cholesterol the control group is higher. It is seen that the damaged group of the quantity of HDL cholesterol is lower frequently in A.I. This fact is presented that HDL cholesterol that cholesterol is exhausted is changed, because of the dan1aged group that replacement is activated. 3. As the observed result of alteration of sebaceous glands, it is appeared that the demage of sebaceous glands is destroyed in the damaged group. It is observed that epidermis of the group applied by Rose essential oil after treated surfactant is dry, secretion of phenomenon of water and sebum is appeared more. It is observed that the epidermis recovery of the group applied by Lavender essential oil after treated surfactant is insufficient. And then it is seen that stratum corneum is recovered and the quantity of sebum secretion is decreased. 4. As the observed result of alteration of Mast cell group treated by Rose essential oil and Lavender essential oil for 3 weeks Luna's stain(${\times}100$), it is observed that the damaged group treated by Lavender essential oil is numerous in alteration of mast cell's number and Mast cell's size is larger than the dan1aged group. It is presented that the Mast cell's number and Mast cell's size is larger than the damaged group, the Mast cell's size and quantity of the group treated by Rose essential oil and Lavender essential oil is decreased more.

• 통합자연과학논문집
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• 제16권2호
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• pp.53-59
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• 2023

Lavender oil is a prolonged history in ancient medicine and has a wide range of biological effects. The lavender essential oil has 50 different constituents that have different therapeutic significance. The compounds that are separated from essential oil can be used for the anticancer treatment of non-small cell lung cancer. ROS1 is one of the major targets for NSCLC. The compounds from lavender essential oil are separated through GC-MS. From 91 compounds the top compounds that are having high retention values are taken for Molecular docking study against the ROS1 target protein. The binding affinity and the docked pose for those compounds are studied. Later, the chemical reactivity of the compounds is studied by Density Functional Theory. The potent compounds must be validated by in vivo study.

• Journal of Korean Academy of Oral Health
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• 제42권4호
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• pp.210-215
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• 2018

Objectives: The main objectives of this study were to verify the antibacterial activity of two essential oils, lavender and peppermint, against dental caries and to review their synergistic effect when used in combination. Our results provide basic data for the evaluation of the use of these two substances towards the prevention and cure of dental caries. Methods: The sample solutions of lavender and peppermint oils were prepared in three different concentrations (30%, 50%, and 70% (v/v)) by diluting them with third-distilled water and Tween 20. Streptococcus mutans was selected as the bacterial species for testing. The disk diffusion method was used to measure the antibacterial activity of the sample solutions. For generating growth curves and measuring the number of clusters of the bacterial, the liquid medium-dilution method was used; the absorbance of the medium was measured at 600 nm after 3, 6, 12 and 24 hours. Results: When the antibacterial activity of the oils was tested via the disk diffusion method, the activity improved with increasing concentrations of all the sample solutions of peppermint, lavender, and the blend, but there was no significant difference between them with respect to the type of oil. In the growth curves of S. mutans, growth inhibition was observed after 12 hours. The inhibitory effect of 30% lavender oil on growth was 64.9% and 80.1% after 12 and 24 hours of treatment, respectively whereas that of peppermint oil was 71.3% and 80.1% after 12 and 24 hours of treatment, respectively. The inhibitory effect of the blended oil was 71.9% and 81.0% after 12 and 24 hours of treatment, respectively. Conclusions: Further research is still required in order to determine the efficacy of lavender and peppermint oils, as well as other essential oils, for wider use in preventing dental caries.

• 기본간호학회지
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• 제16권3호
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• pp.300-306
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• 2009

Purpose: This study was done to investigate differences between lavender abdominal massage and inhalation on dysmenorrhea, menstrual pain, anxiety, and depression. Methods: This study used a non equivalent quasi-experimental design. Lavender essential oil and almond oil were used in massage and a lavender necklace and artificial perfume necklace in inhalation for female college students. Frequencies, percentages, Chi-square, Fisher's exact test and t-test with the SPSS/WIN 12.0 program were used to analyze the data. Results: Dysmenorrhea was significantly higher inhalation for placebo treatment compared to lavender inhalation (p< .001). There was not significant difference between lavender abdominal massage and inhalation. Conclusion: Lavender abdominal massage and inhalation could be effective methods to reduce dysmenorrhea. However, before lavender abdominal massage and inhalation can be considered as intervention, it is more needed to study of menstrual pain, anxiety and depression.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2001년도 추계학술대회 논문집
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• pp.117-121
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• 2001

본 연구에서는 향에 대한 생리적 반응과 선호도가 노년층과 청년층에서 어떠한 차이가 있는지 살펴보고자 하였다. 20대 및 60대 피험자에게 100％의 Basil oil, Jasmin oil, Lavender oil, Lemon il, Ylangylang oil을 제시하여 자율신경계의 반응인 심전도의 RR간격과 GSR을 측정ㆍ분석하였으며, 선호도 평가를 하여 자율신경계의 반응과의 상관성을 검토하였다. 20대는 Lemon 향에서 RR 간격 및 GSR의 반응이 안정되게 나타났으며, 선호도 평가에서도 Lemon 을 가장 선호도가 높게 평가하는 것을 볼 수 있었다. 60대는 Lavender에서 RR 간격이 증가하고 GSR이 감소하여 안정된 반응을 보였고, Lavender에 대한 선호도 또한 높게 평가하여 60대는 다른 향보다 Lavender를 좋은 향으로 평가함을 알 수 있었다.

• 대한간호학회지
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• 제45권3호
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• pp.367-377
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• 2015

Purpose: The purpose of this study was to evaluate the effects of essential oil on oxidative stress, immunity, and skin condition in atopic dermatitis (AD) induced mice. Methods: This study was a $3{\times}3$ factorial design. Factors were oil type (Lavender, Thyme, and 2:1 mixture of lavender and thyme oil [blending oil]) and treatment period (0 day, 7 days, and 21 days). The samples were 45 mice with AD and randomly assigned to nine groups of five mice per group. The dependent variables such as superoxide radical, IgE, degranulated mast cells, and epidermal thickness were measured. Data were collected from February to April in 2014. Descriptive statistics, One-way ANOVA, Two-way ANOVA, and Tukey's HSD test were performed using the SPSS WIN 20.0 program. Results: Dependent variables were not statistically significantly different by the three oil types (p >.05). Essential oils such as lavender, thyme, and blending oil were all effective in reducing AD symptoms and especially 2:1 blending oil were most effective. There were statistically significant differences by the three treatment periods in all dependent variables (p <.001). There were statistically significant interactions between oil types and treatment periods in all dependent variables (p <.01). For decreasing superoxide radical, degranulated mast cells, and epidermal thickness, 2:1 mixed oil should be applied for at least 21 days. Otherwise to reduce IgE, 2:1 mixed oil should be used for at least 7 days. Conclusion: These findings provide bases for developing effective interventions for AD patients to manage their AD symptoms.