• The Korean Journal of Physiology and Pharmacology
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• v.8 no.2
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• pp.89-94
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• 2004

The arterial pressure is regulated by the nervous and humoral mechanisms. The neuronal regulation is mostly carried out by the autonomic nervous system through the rostral ventrolateral medulla (RVLM), a key area for the cardiovascular regulation, and the humoral regulation is mediated by a number of substances, including the angiotensin (Ang) II and vasopressin. Recent studies suggest that central interleukin-1 (IL-1) activates the sympathetic nervous system and produces hypertension. The present study was undertaken to elucidate whether IL-1 and Ang II interact in the regulation of cardiovascular responses to the stress of hemorrhage. Thus, Sprague-Dawley rats were anesthetized and both femoral arteries were cannulated for direct measurement of arterial pressure and heart rate (HR) and for inducing hemorrhage. A guide cannula was placed into the lateral ventricle for injection of IL-1 $(0.1,\;1,\;10,\;20\;ng/2\;{\mu}l)$ or Ang II $(600\;ng/10\;{\mu}l)$. A glass microelectrode was inserted into the RVLM to record the single unit spike potential. Barosensitive neurons were identified by an increased number of single unit spikes in RVLM following intravenous injection of nitroprusside. I.c.v. $IL-1\;{\beta}$ increased mean arterial pressure (MAP) in a dose-dependent fashion, but HR in a dose-independent pattern. The baroreceptor reflex sensitivity was not affected by i.c.v. $IL-1\;{\beta}$. Both i.c.v. $IL-1\;{\alpha}\;and\;{\beta}$ produced similar increase in MAP and HR. When hemorrhage was induced after i.c.v. injection of $IL-1\;{\beta}$, the magnitude of MAP fall was not different from the control. The $IL-1\;{\beta}$ group showed a smaller decrease in HR and a lower spike potential count in RVLM than the control. MAP fall in response to hemorrhage after i.c.v. injection of Ang II was not different from the control. When both IL-1 and Ang II were simultaneously injected i.c.v., however, MAP fall was significantly smaller than the control, and HR was increased rather than decreased. These data suggest that IL-1, a defense immune mediator, manifests a hypertensive action in the central nervous system and attenuates the hypotensive response to hemorrhage by interaction with Ang II.

• Korean Journal of Materials Research
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• v.11 no.7
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• pp.575-579
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• 2001

GaN buffer layer and epilayer have been grown on sapphire (0001) by metal organic chemical vapor deposition (MOCVD). GaN buffer layer ranging from 26 nm to 130 nm in thickness was grown at 55$0^{\circ}C$ prior to the 4 $\mu\textrm{m}$ thick GaN epitaxial deposition at 110$0^{\circ}C$. After GaN buffer layer growth, buffer layer surface was examined by atomic force microscopy (AFM). As the thickness of GaN buffer layer was increased, surface morphology of GaN epilayer was investigated by scanning electron microscopy (SEM). Double crystal X-ray diffraction (DCXRD) and Raman spectroscopy were employed to study crystallinity of GaN epilayers. Optical properties of GaN epilayers were measured by photoluminescence (PL). The epilayer grown with a thin buffer layer had rough surface, and the epilayer grown with a thick buffer layer had mirror-like surface of epilayer. Although the stress on the latter was larger than on the former, its crystallinity was much better. These results imply that the internal free energy is decreased in case of the thick buffer layer. Decrease in internal free energy promotes the lateral growth of the GaN film, which results in the smoother surface and better crystallinity.

• Geophysics and Geophysical Exploration
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• v.13 no.3
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• pp.256-267
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• 2010

Earthquakes in the Korean Peninsula occur along the faults formed and boundaries between major geological units ruptured due to violent tectonic activities during the Mesozoic. E-W and/or ENE-SSW compressive stress regime resulting from collisions between the Eurasian plate and neighbouring the Indian plate, the Pacific plate and the Philippine plate trigger Korean earthquakes of thrust faulting with predominant strike-slip components along the mostly NNE-SSW trending active faults. Seismicity of the Korean peninsula has been moderate to low during the past 20 centuries except for the period from the 15th to the 18th centuries of exceptionally high seismicity, showing the typical irregularity of intraplate seismicity. The structure of the Korean peninsula is rather homogeneous without the Conrad discontinuity sharply dividing the upper and lower crust. Lateral heterogeneities exist in the crust. The crust with an average thickness of about 33 km is thicker in the mountainous region than the plain due to the Airy-type isostatic equilibrium maintained in the peninsula. Crustal P-wave velocity with average of about 6.3 km/sec increases gradually from the near surface to the Moho. The upper mantle P-wave (Pn) velocity is about 7.8 km/sec.

• Journal of the Korean Arthroscopy Society
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• v.6 no.2
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• pp.115-120
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• 2002

Purpose : To compare the functional evaluation with the posterior translation after arthroscopic PCL reconstruction in isolated and combined PCL-deficient knees. Materials and Methods : We retrospectively evaluated 45 patients with PCL-deficient knees who were treated by arthroscopic PCL reconstruction using Achilles tendon allograft from June 1994 to June 2000. The differences of posterior translation were measured with posterior stress lateral radiographs and KT-2000 arthrometer. The functional results were evaluated using the Lysholm knee score and IKDC evaluation form. Results : Preoperative mean side to side differences of the posterior translation were 11.83 mm in isolated PCL-deficient knees and 12.7 mm in combined PCL-deficient knees respectively. At the last follow-up in isolated and combined PCL-deficient knees, the mean radiographic side to side differences of the posterior translation were 6.38 mm and 6.7 mm, the average corrected 20 Ib posterior displacements using KT-2000 arthrometer were 3.5 mm and 4.1 mm, the mean Lysholm score were 87.4 and 81.2, the grade A and B of IKDC evaluation form were 16 cases $(88.9\%)$ and 23 cases $(85.2\%)$, respectively. Conclusion : The functional results had no relationship with the degree of posterior translation after arthroscopic PCL reconstruction. Tendency of posterior translation may be influenced by associated injury of the knee.

• Geophysics and Geophysical Exploration
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• v.14 no.2
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• pp.127-132
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• 2011

We acquired and interpreted more than 650 km of high-resolution seismic reflection profiles in the Hupo Basin, offshore east coast of Korea at $37^{\circ}N$ in the East Sea (Japan Sea) to image shallow and basement deformation. The seismic profiles reveal that the main depocenter of the Hupo Basin in the study area is bounded by the large offset Hupo Fault on the east and an antithetic fault on the west; however, the antithetic fault is much smaller both in horizontal extension and in vertical displacement than the Hupo Fault. Sediment infill in the Hupo Basin consists of syn-rift (late Oligocene. early Miocene) and post-rift (middle Miocene.Holocene) units. The Hupo Fault and other faults newly defined in the Hupo Basin strike dominantly north and show a sense of normal displacement. Considering that the East Sea has been subjected to compression since the middle Miocene, we interpret that these normal faults were created during continental rifting in late Oligocene to early Miocene times. We suggest that the current ENE direction of maximum principal compressive stress observed in and around the Korean peninsula associated with the motion of the Amurian Plate induces the faults in the Hupo Basin to have reverse and right-lateral, strike-slip motion, when reactivated. A recent earthquake positioned on the Hupo Fault indicates that in the study area and possibly further in the eastern Korean margin, earthquakes would occur on the faults created during continental rifting in the Tertiary.

• Journal of the Korea Concrete Institute
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• v.14 no.6
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• pp.1001-1009
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• 2002

The objective of this study is to determine the range of confinement (or the transverse reinforcement of the reinforced concrete structural walls with the T-shaped cross section subjected to cyclic lateral loads. The range of confinement for transverse reinforcement is related to the location of neutral axis and determined by the magnitude and distribution of compressive strain. The compressive strain depends on the ratio of wall cross sectional area to the floor-plan area, the aspect ratio, configuration, the axial load, and the reinforcement ratios. By affection of flange, the neutral axis appears different depending on positive and negative forces and because of this reason, when web and flange are subjected to compressive stress, the range of confinement for the transverse reinforcement of T-shaped walls would shows different result. Therefore this experimental research focused on the structural characteristics of T-shaped walls and suggested the neutral axis depth through comparing the results of this study with sectional analysis.

• Journal of the Korean GEO-environmental Society
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• v.10 no.3
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• pp.21-28
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• 2009

As the natural aggregates such as sand and clay are getting exhausted, the quantity of utilizing geosynthetics is being increased in the solid waste landfill. Especially, the waste landfills have been constructed at the gorge in the mountainous area and reclaimed land from the sea in the Korean Peninsula. Those areas are not favorable for construction of waste landfill in geotechnical engineering aspect. In this study, the frictional characteristics of geosynthetics that used in the waste landfill were estimated. Then, the studies of the behavior of geosynthetics and stability of LDCRS (Leachate Detection, Collection, and Removal System) of side slope were conducted in the waste landfill by means of the pilot test, and numerical analysis. Geocomposite which is combined type or separated type is influenced on the strain itself, and also implicated in the stress and strain of geomembrane at the lower layer. The strain on the combined type of geocomposite is about 50% smaller than that of the separated type at the side slope. The lateral displacement and settlement of top at the slope with the separated type are three times greater than that of the combined type. In the numerical analysis, discontinuous plans in between ground and geosynthetic, geosynthetic and geosynthetic, goesynthetic and waste have been modeled with the interface element. The results gave a good agreement with the field large-scale model test. The relative displacements of geosynthetics were also investigated and hence the interface modeling of liner system is appropriate for analysis of geosynthetics liner system in the waste landfill.

• Journal of the Korea Concrete Institute
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• v.18 no.3 s.93
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• pp.405-414
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• 2006

In the present study, a numerical analysis was performed for interior connections of continuous flat plate to analyze the effect of design parameters such as column section shape, gravity load and slab span on the behavioral characteristics of the connections. For the purpose, a computer program for nonlinear FE analysis was developed, and the validity was verified. Through the parametric study, the variations of shear stress distribution around the connection were investigated. According to the result of numerical analysis, as the length of the cross section of column in the direction of lateral load increases and gravity load increases, the effective area and the maximum shear strength providing the torsional resistance decrease considerably. And as the slab span loaded with relatively large gravity load increases, the negative moment around the connection increases and therefore the strength of connection against unbalanced moment decreases. By considering the effect of design parameters on the strength of the connections, the effective shear strength to calculate the torsional moment capacity of connection was proposed and the effectiveness of the proposed shear strength was verified.

• Proceedings of the Korean Magnestics Society Conference
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• 2010.06a
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• pp.79-79
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• 2010

Semimetallic bismuth (Bi) has been extensively investigated over the last decade since it exhibits very intriguing transport properties due to their highly anisotropic Fermi surface, low carrier concentration, long carrier mean free path l, and small effective carrier mass $m^*$. In particular, the great interest in Bi nanowires lies in the development of nanowire fabrication methods and the opportunity for exploring novel low-dimensional phenomena as well as practical application such as thermoelectricity[1]. In this work, we introduce a self-assembled interconnection of nanostructures produced by an on-film formation of nanowires (OFF-ON) method in order to form a highly ohmic Bi nanobridge. A Bi thin film was first deposited on a thermally oxidized Si (100) substrate at a rate of $40\;{\AA}/s$ by radio frequency (RF) sputtering at 300 K. The sputter system was kept in an ultra high vacuum (UHV) of $10^{-6}$ Torr before deposition, and sputtering was performed under an Ar gas pressure of 2m Torr for 180s. For the lateral growth of Bi nanowires, we sputtered a thin Cr (or $SiO_2$) layer on top of the Bi film. The Bi thin films were subsequently put into a custom-made vacuum furnace for thermal annealing to grow Bi nanowires by the OFF-ON method. After thermal annealing, the Bi nanowires cannot be pushed out from the topside of the Bi films due to the Cr (or $SiO_2$) layer. Instead, Bi nanowires grow laterally as a mean s of releasing the compressive stress. We fabricated a self-assembled Bi nanobridge (d=192 nm) device in-situ using OFF-ON through annealing at $250^{\circ}C$ for 10hours. From I-V measurements taken on the Bi nanobridge device, contacts to the nanobridge were found highly ohmic. The quality of the Bi nanobridge was also proved by the high MR of 123% obtained from transverse MR measurements. These results manifest the possibility of self-assembled nanowire interconnection between various nanostructures for a variety of applications and provide a simple device fabrication method to investigate transport properties on nanowires without complex patterning and etching processes.

• Journal of the Earthquake Engineering Society of Korea
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• v.11 no.2 s.54
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• pp.95-104
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• 2007

Three types of high-rise RC building structures having irregularity in the lower two stories were selected as prototypes and were performed nonlinear static analysis by using OpenSees to verify the analysis technique and to investigate the seismic capacity of those buildings. The first one has a symmetrical moment resisting frame (Model 1), the second has an infilled shear wall in the central frame (Model 2), and the third has an infilled shear wall only in one of exterior frames (Model 3). Fiber model, which consists of concrete and reinforcing bar represented from stress-strain relationship, is adapted used for simulate the nonlinearity of members, and MVLEM(Multi vertical linear element model) is used for simulate the behavior of wall. The analytical results are simulate the behavior of piloti stories well, for example, the stiffness and yield farce of piloti stories, the up-lift of wall and the variation of lateral stiffness of column due to the variation of axial forces. Overstrength of Model 2 and Model 3 are about 2 times larger than that of Model 1. The reason of the high oversttrength and ductility of Model 2 and Model 3 is that the conservative design of Model 2 and Model 3, whose beam and column sections are the same as those of Model 1. The ductilities of Model 1 and Model 3 are slightly larger than that of Model 1 and Model 3. Model 1 and Model 3 reached mechanism condition, whereas Model 2 failed to the shear failure of shear wall and the large axial forces in columns due to large overturning moment.