• Title/Summary/Keyword: Late enhancement

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A Portable Wireless EEG System for Neurofeedback: Design and Implementation

  • Chen, Hai-Feng;Ye, Dong-Hee;Kang, Young-Ho;Lee, Jung-Tae
    • Journal of Biomedical Engineering Research
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    • v.28 no.4
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    • pp.461-470
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    • 2007
  • Human can learn how to shape their brain electrical activity in a desired direction through continuous feedback of the electroencephalogram (EEG), and this technique is known as Neurofeedback (or EEG biofeedback), which has been used since the late 1960s in clinical applications. In this study, a portable wireless EEG (named wEEG) has been designed and implemented, which consists of a mobile station (a wireless two-channel EEG acquisition device) and a base station (a bridge between mobile station and computer). Moreover, a SensoriMotor Rhythm (SMR) training system was also implemented with the wEEG for enhancing attention with virtual environment. Experiment results based on 16 volunteers' (8 females and 8 males, average age is $27{\pm}4$) were reported in this paper. The results show that the SMR ratio of 87.5% subjects increased about 0.7% in training status than that in the stable status. With the proposed system, many training protocol scan be designed easily and can be done at home in our daily life conveniently. Additionally, the proposed system will be useful for disabled and aged people.

The peduncle-specific expression during floral transition by high-throughput transcriptome analysis in wheat

  • Lee, Cheol Won;Seo, Yong Weo
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.87-87
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    • 2017
  • Flowering time of either early or late is one of the crucial parameters that determine the crop productivity. Therefore, elucidation of regulatory mechanisms of flowering time should contribute to breeding for yield enhancement. However, comprehensive explanation on molecular mechanism of flowering has not yet been reported in hexaploidy common wheat (Triticum asetivum L.). The mechanism of flowering in wheat has been studied mostly using flag leaf or floral meristem. The exposed peduncle, which is a shoot part between bottom of the spike and flag leaf, could be an important tissue that is responsible for flowering through various molecules expressing. To clarify for transcriptomic dynamics in the wheat peduncle that was uncovered by leaf sheath of flag leaf, RNA sequencing and transcriptomic analysis were conducted. With this, we also analyzed other transcriptomic results deposited in the public DB to identify genes specially expressed in peduncle tissue at transition from vegetative to reproductive phase. The obtained results will provide valuable information to understand the role of peduncle for flowing regulation in wheat aimming for elucidation of the regulatory mechanism of wheat flowering.

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The Role of Enzyme Replacement Therapy in Fabry Disease in Cardiology Perspective

  • Hongo, Kenichi
    • Journal of mucopolysaccharidosis and rare diseases
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    • v.4 no.1
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    • pp.21-25
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    • 2018
  • Fabry disease is a hereditary lysosomal storage disorder caused by the reduction or absence of lysosomal enzyme alpha-galactosidase A and the accumulation of glycosphingolipids, such as globotriaosylceramide (Gb3), in various organs, including the heart. The prevention of cardiac involvement in Fabry disease can only be achieved by enzyme replacement therapy (ERT), and the method of assessing the efficacy of ERT should be confirmed. Changes in the electrocardiogram, such as the shortening of PQ interval, prolongation of QTc and repolarization abnormalities as well as left ventricular hypertrophy in voltage criteria, can be used to identify Fabry disease patients; however, the usefulness of electrocardiograms for evaluating the efficacy of ERT is limited. The assessment of left ventricular hypertrophy using echocardiography has been established to evaluate the efficacy of ERT during long-term period. A new technique involving speckled tracking method might be useful for detecting early cardiac dysfunction and identifying the effect of ERT for a relatively short period. The estimation of left ventricular hypertrophy using cardiac magnetic resonance (CMR) is also useful for assessing the efficacy of ERT. Identifying late gadolinium enhancement in CMR may affect the effectiveness of ERT, and the new technique of T1 mapping might be useful for monitoring the accumulation of Gb3 during ERT. Histopathology in cardiac biopsy specimens is another potentially useful method for identifying the accumulation of GB3; however, the use of histopathology to evaluate of the efficacy of ERT is limited because of the invasive nature of an endomyocardial biopsy.

Paleoceanographic Records from the Northern Shelf of the East China Sea since the Last Glacial Maximum

  • Li, Bao-Hua;Park, Byong-Kwon;Kim, Dong-Seon
    • Journal of the korean society of oceanography
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    • v.34 no.3
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    • pp.151-166
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    • 1999
  • Both benthic and planktonic foraminifera from Core 97-02 obtained in the northern East China Sea are quantitatively analyzed for reconstructing the paleocenography of late Quaternary. Since the earliest time of the core sediment (last not older than 18000 yr B.P.), the paleo-water depth has changed from less than 20 m to near 100 m at present, which is reflected by the benthic foraminiferal assemblages: before 14000 yr B.P., the water depth was shallower than 20 m; from 14000 to 7500 yr B.P., water depth was 20-50 m; and after 7500 yr B.P., water depth was 50-100 m. The foraminiferal fauna also disclose the water mass history: during the last glacial maximum, the water that dominated the study area might be the coastal water; at the end of the last glacial maximum(14000-9500 yr B.P.), the Yellow Sea Cold Water mostly affected this area; then it gave way to the Yellow Sea Warm Current after 9500 yr B.P.; and finally, the warm water has dominated this area since 9500 yr B.P. because of the westward shift and enhancement of the Kuroshio Current.

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An Experimental Study on the Effect of Irradiation and cia- dichlorodiBmmineplatinum(II) on the myocardium of Rats (방사선조사와 cis-dichlorodismmineplstinum(II)가 휜쥐의 심근에 미치는 효과에 관한 실험적 연구)

  • Lee Kyung-Ja
    • Radiation Oncology Journal
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    • v.12 no.3
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    • pp.285-293
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    • 1994
  • Purpose : The study was designed to investigate the effect of cis-dichlorodiammineplatinum(II)(cis-DDP) on the radiation-induced cardiomyopathy in the rat. Materials and Methods : The myocardial damage was assessed by histopathologic changes. In radiation alone group, radiation dose ranged from 10-40 Gy X-ray in a single dose and in combined group, cis-dichlorodiammineplatinum(II) at a dose of 6 mg/kg was given intraperitoneally immediately after irradiation of same dose with X-ray alone group. Results : The early changes by radiation included congestion, inflammatory cell infiltrations and fibrosis in myocardial interstitium with focal myocardial necrosis, which was noted in 10 Gy group, Myocardial fibrosis was increased by increasing dose of radiation but myocardial necrosis was not Proportional to radiation dose. cis-DDP alone group showed minimal degeneration of myocardium with surrounded by inflammatory cell infiltrations. In combined group, myocardial fibrosis in 10 Gy group were similar to radiation alone group, but 30 Gy and 40 Gy groups showed severer changes. Electron microscopic examination showed disruption of Z-band and edema of mitochondria with decreased matrix density in 20 Gy radiation group which were severer in 40 Gy radiation group. Combined group showed endothelial changes and disruption of Z-band worse than radiation alone group as well as increased connective tissue, which was considered as a hallmark of late change in radiation-induced heart disease. Conclusion : This results showed minimal enhancement of the radiation-induced cardiomyopathy in rats by cis-DDP.

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Biocontrol of Late Blight and Plant Growth Promotion in Tomato Using Rhizobacterial Isolates

  • Lamsal, Kabir;Kim, Sang Woo;Kim, Yun Seok;Lee, Youn Su
    • Journal of Microbiology and Biotechnology
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    • v.23 no.7
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    • pp.897-904
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    • 2013
  • Seven bacterial isolates (viz., AB05, AB10, AB11, AB12, AB14, AB15, and AB17) were derived from the rhizosphere and evaluated in terms of plant growth-promoting activities and the inhibition of Phytophthora infestans affecting tomatoes in Korea. According to 16S rDNA sequencing, a majority of the isolates are members of Bacillus, and a single isolate belongs to Paenibacillus. All seven isolates inhibited P. infestans by more than 60% in vitro. However, AB15 was the most effective, inhibiting mycelial growth of the pathogen by more than 80% in vitro and suppressing disease by 74% compared with control plants under greenhouse conditions. In a PGPR assay, all of the bacterial isolates were capable of enhancing different growth parameters (shoot/root length, fresh biomass, dry matter, and chlorophyll content) in comparison with non-inoculated control plants. AB17-treated plants in particular showed the highest enhancement in fresh biomass with 18% and 26% increments in the root and shoot biomass, respectively. However, isolate AB10 showed the highest shoot and root growth with 18% and 26% increments, respectively. Moreover, the total chlorophyll content was 14%~19% higher in treated plants.

Cultural Property in the territory of the North Korea considered from 'the law of the Democratic People's Republic of Korea on Protection of Cultural Property' (「문화유물보호법」을 통해 본 북한의 문화유산)

  • JI, Byong-Mok
    • Korean Journal of Heritage: History & Science
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    • v.36
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    • pp.39-67
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    • 2003
  • In this paper we examine cultural properties of the North Korea from 'the law of the Democratic People's Republic of Korea on Protection of Cultural Property". This law was adopted the Resolution of the Standing Committee of the Supreme People's Assembly of DPR of Korea in 1994. For our study, some other laws or rules established after the end of Japanese colonial occupation (1910-1945) in North Korea were examined. The policy on protection and conservation of cultural property in North Korea seems to have taken place a relatively rapid. The purpose of this law is to carry out the policy with a view to contributing to establishment of strict system and order for protection and management of cultural property, to their preservation in original state, to their proper inheritance and development, and to enhancement of national pride and confidence among the people. This law consists of 6 chapters (52 articles): (1) Fundamentals of the law on protection of cultural property, (2) Archaeological excavation and collection of cultural relics, (3) Evaluation and registration of cultural property, (4) Preservation and management of cultural property, (5) Restoration of cultural property, and (6) Guidance and control of cultural property protection. Nevertheless, it is difficult to find the evidence of efforts to exploit the cultural properties from an academic point of view in North Korea since the late 1980s.

Changes in flavor-relevant compounds during vine ripening of tomato fruit and their relationship with ethylene production

  • Wang, Libin;Luo, Weiqi;Sun, Xiuxiu;Qian, Chunlu
    • Horticulture, Environment, and Biotechnology : HEB
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    • v.59 no.6
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    • pp.787-804
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    • 2018
  • Flavor quality is import for determining consumer perception and acceptance of tomato products. In this study, 'Fendou' tomato fruit were harvested at six ripening stages and sampled to investigate the development of flavor-relevant compounds during vine ripening. Results showed that upon the initiation of ripening there was an increase in respiration rate and concomitant ethylene evolution that was associated with increased membrane permeability. In accordance with these physiological changes, flavor-relevant compounds demonstrated different expression patterns as fruit ripened, which contributed to 'red-ripe' flavor characteristics of red-ripe fruit. Based on correlation analysis between ethylene evolution and the flavor-relevant compounds during 'Fendou' tomato ripening and the other researchers' reports, the activation of System 2-dependent autocatalytic ethylene production plays an important role in the development of most flavor-relevant compounds during tomato vine ripening. Overall, our results suggested that most flavor-relevant compounds that accumulated the most during tomato fruit ripening at red stage could be under ethylene regulation and were among the most important contributors to the 'red-ripe' flavor. Due to the development of these compounds, the flavor quality at late ripening stages is different from that of fruit at early ripening stages.

Chemical properties of star-forming galaxies in Virgo-related large-scale filamentary structures.

  • Chung, Jiwon;Rey, Soo-Chang;Kim, Suk;Lee, Youngdae;Sung, Eon-Chang
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.2
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    • pp.75.3-75.3
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    • 2019
  • The filament is an interesting structure in the Universe because clusters form at the nodes of filaments and grow through the continuous accretion of individual galaxies and groups from the surrounding filaments. We study the chemical properties of star-forming (SF) galaxies in the five large-scale filamentary structures (Leo II A, Leo II B, Leo Minor, Canes Venatici, and Virgo III) related with the Virgo cluster, with the spectroscopic data taken with the SDSS DR12, and compare them with those of the Virgo cluster and field galaxies. In mass-metallicity relation, most of the SF galaxies in Virgo-related filaments (except Virgo III filament) show lower metallicity on average than the Virgo cluster SF galaxies, but similar to field counterparts. These chemically less evolved feature of SF galaxies in the filaments and field are more pronounced for lower mass galaxies. This is probably because low mass galaxies have low potential wells and are therefore likely to be sensitive to cluster environmental effects. Interestingly, we find that the metallicity enhancement of SF galaxies in the Virgo III filament. In chemical and morphological perspectives, SF galaxies in the Virgo III thought to be transitional objects possibly transformed from SF late-type galaxies and are on the way to red early-type galaxies in the filament environment. This is the first discovery of systematic 'chemical pre-processing' signature for filament galaxies in Local Universe before they fall into the cluster.

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Utilities and Limitations of Cardiac Magnetic Resonance Imaging in Dilated Cardiomyopathy

  • Min Jae Cha;Yoo Jin Hong;Chan Ho Park;Yoon Jin Cha;Tae Hoon Kim;Cherry Kim;Chul Hwan Park
    • Korean Journal of Radiology
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    • v.24 no.12
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    • pp.1200-1220
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    • 2023
  • Dilated cardiomyopathy (DCM) is one of the most common types of non-ischemic cardiomyopathy. DCM is characterized by left ventricle (LV) dilatation and systolic dysfunction without coronary artery disease or abnormal loading conditions. DCM is not a single disease entity and has a complex historical background of revisions and updates to its definition because of its diverse etiology and clinical manifestations. In cases of LV dilatation and dysfunction, conditions with phenotypic overlap should be excluded before establishing a DCM diagnosis. The differential diagnoses of DCM include ischemic cardiomyopathy, valvular heart disease, burned-out hypertrophic cardiomyopathy, arrhythmogenic cardiomyopathy, and non-compaction. Cardiac magnetic resonance (CMR) imaging is helpful for evaluating DCM because it provides precise measurements of cardiac size, function, mass, and tissue characterization. Comprehensive analyses using various sequences, including cine imaging, late gadolinium enhancement imaging, and T1 and T2 mapping, may help establish differential diagnoses, etiological work-up, disease stratification, prognostic determination, and follow-up procedures in patients with DCM phenotypes. This article aimed to review the utilities and limitations of CMR in the diagnosis and assessment of DCM.