• 제목/요약/키워드: Late effects

검색결과 1,279건 처리시간 0.033초

The Long-Term Effects of Familial Difficulties Experienced in Childhood: Predictors of Internalizing Behavior Problems during the Early Adolescent Period and Late Life Periods

  • Sohn Byoungduk
    • International Journal of Human Ecology
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    • 제6권1호
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    • pp.103-115
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    • 2005
  • This study utilized data (a sample of 18,553 people born in 1958 in England, Scotland, and Wales) from the National Child Development Study of 1968 and 1991 to explore the influence of familial difficulties on the internalizing behavioral patterns during the early adolescent period and late life outcomes periods. In this paper, internalizing behavioral problems include 'depression', 'anxiety', 'hostility to adults', 'hostility to children', and 'withdrawal'. Late outcomes were analyzed in two different variables and one marital management domain: 'unemployment', 'seen doctors about emotional problems', 'divorce or separation; never lived as a couple; arguments end in violent behavior' The results indicate that young adolescents who had experienced familial difficulties also have internalizing behavioral problems giving them emotional and behavioral instability. The findings also show that familial difficulties during childhood positively contribute to late life outcomes such as unemployment, emotional problems, and marital management. This study suggests that in order to effectively respond to the needs of children and adolescents who have experienced various familial difficulties, counselors and educators must guide parents.

표고버섯의 채취 시기 및 부위별 영양성분 함량 비교 (Component Comparions of the Nutrient Composition of Lentinus Edodes based of Harvest Period)

  • 박홍주;이성현;백오현;조수묵;조용식
    • 한국지역사회생활과학회지
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    • 제15권3호
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    • pp.107-112
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    • 2004
  • Many studies have showen that Letinus edodes have a reducing effects on blood pressure and lipid levels in animals with high blood pressure and hyperlipidemia. But the only cap has been on the market as goods and the stipe has been wasted. The price is very variable and is based on harvest time and the part of the plant currenty, there is not much information about the nutritional composition and bio-fuctional effects of Letinus edodes based on harvest time and part. Some farmers have been selling the powder seasoning by drying and pulverizing Letinus edodes including stipe to develop value added, late harvested Letinus edodes and its stipe these days. This study was conducted to investigate and compare the nutritional composition of Letinus edodes harvested at different times (early: E, late: L) and separated by part (cap: C, stipe: S). The 4 kinds of materials were named as early harvested cap (EC) and stipe (ES), and late harvested cap (LC) and stipe (LS) samples were obtained from Mungyeong City Agricultural Technology & Extension Center. The composition analysis of the nutrients in the 4 materials was conducted by using the AOAC method. The proximate components (moisture, protein, fat, fiber, ash, and carbohydrates), minerals and vitamin content were measured. Nutritional composition of Lentinus edodes did not show any significant difference between early and late harvested mushrooms. Nutritional compositions were different according to part. The results demonstrate that the late harvested stipe can also be used as a quality food material.

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Effect of Feeding a Mixed Microbial Culture Fortified with Trace Minerals on the Performance and Carcass Characteristics of Late-fattening Hanwoo Steers: A Field Study

  • Kwak, W.S.;Kim, Y.I.;Lee, S.M.;Lee, Y.H.;Choi, D.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • 제28권11호
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    • pp.1592-1598
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    • 2015
  • This study was conducted to determine the effects of feeding a trace minerals-fortified microbial culture (TMC) on the performance and carcass characteristics of late-fattening Hanwoo steers. A mixture of microbes (0.6% [v/w] of Enterobacter sp., Bacillus sp., Lactobacillus sp., and Saccharomyces sp.) was cultured with 99% feedstuff for ensiling and 0.4% trace minerals (zinc, selenium, copper, and cobalt). Sixteen late-fattening steers (mean age, 21.8 months) were allocated to two diets: a control diet (concentrate mix and rice straw) and a treated diet (control diet+3.3% TMC). At a mean age of 31.1 months, all the steers were slaughtered. The addition of TMC to the diet did not affect the average daily weight gain of the late fattening steers, compared with that of control steers. Moreover, consuming the TMC-supplemented diet did not affect cold carcass weight, yield traits such as back fat thickness, longissimus muscle area, yield index or yield grade, or quality traits such as meat color, fat color, texture, maturity, marbling score, or quality grade. However, consumption of a TMC-supplemented diet increased the concentrations of zinc, selenium, and sulfur (p<0.05) in the longissimus muscle. With respect to amino acids, animals consuming TMC showed increased (p<0.05) concentrations of lysine, leucine, and valine among essential amino acids and a decreased (p<0.05) concentration of proline among non-essential amino acids. In conclusion, the consumption of a TMC-supplemented diet during the late-fattening period elevated the concentrations of certain trace minerals and essential amino acids in the longissimus muscle, without any deleterious effects on performance and other carcass characteristics of Hanwoo steers.

Seizures and Epilepsy following Aneurysmal Subarachnoid Hemorrhage: Incidence and Risk Factors

  • Choi, Kyu-Sun;Chun, Hyoung-Joon;Yi, Hyeong-Joong;Ko, Yong;Kim, Young-Soo;Kim, Jae-Min
    • Journal of Korean Neurosurgical Society
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    • 제46권2호
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    • pp.93-98
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    • 2009
  • Objective: Although prophylactic antiepileptic drug (AED) use in patients with aneurysmal subarachnoid hemorrhage (SAH) is a common practice, lack of uniform definitions and guidelines for seizures and AEDs rendered this prescription more habitual instead of evidence-based manner. We herein evaluated the incidence and predictive factors of seizure and complications about AED use. Methods: From July 1999 to June 2007, data of a total of 547 patients with aneurysmal SAH who underwent operative treatments were reviewed. For these, the incidence and risk factors of seizures and epilepsy were assessed, in addition to complications of AEDs. Results: Eighty-three patients (15.2%) had at least one seizure following SAH. Forty-three patients (79%) had onset seizures, 34 (6.2%) had perioperative seizures, and 17 (3.1%) had late epilepsy. Younger age (< 40 years), poor clinical grade, thick hemorrhage, acute hydrocephalus, and rebleeding were related to the occurrence of onset seizures. Cortical infarction and thick hemorrhage were independent risk factors for the occurrence of late epilepsy. Onset seizures were not predictive of late epilepsy. Moreover, adverse drug effects were identified in 128 patients (23.4%) with AEDs. Conclusion: Perioperative seizures are not significant predictors for late epilepsy. Instead, initial amount of SAH and surgery-induced cortical damage should be seriously considered as risk factors for late epilepsy. Because AEDs can not prevent early postoperative seizures (< 1 week) and potentially cause unexpected side effects, long-term use should be readjusted in high-risk patients.

생쥐 배아 동결시 전핵의 발생시기가 생존률과 발생률에 미치는 영향 (Effects of the Age of Pronucleate Ova on Survival and Development in Cryopreservation of Mouse Embryos)

  • 양현원;강희규;최규완;차영범;이승재;박종민
    • Clinical and Experimental Reproductive Medicine
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    • 제20권1호
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    • pp.31-36
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    • 1993
  • The effects of freezing and 1,2-propanediol on early and late pronucleate stage mouse ova were investigated in terms of survival after thawing and development in vitro. The samples were divided into two groups according to different age in pronucleate ova: ova in(1) early pronuclear stage with two distant pronuclei at 18h after hCG injection, and (2) late pronuclear stage with adjacent pronuclei at 30h. Zygotes in the late pronuclear stage have been proven to be more resistant to 1,2-propanediol, showing a significantly higher developmental rate than zygotes in early stage (80.3 versus 66.3%, <0.05), but survival rate was similar in the two groups (91.0 versus 93.5%). After freezing and thawing, survival and developmental rates were decreased in both groups when compared to the control group (54.3 versus 92.3%, 47.7 versus 73.3%. respectively). And developmental rate in the late pronuclear stage zygotes showed significantly higher than in early (55.4 versus 40.0%) after thawing. In conclusion, early pronucleate mouse ova have a lower developmental capacity in vitro and a lower survival rate after freezing and thawing than late ova. These findings suggest that the timing of freezing could be important for survival and further development in vitro in cryopreservation of human pronucleate ova.

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후기 아동기 학교적응 변화에 대한 부모 방임과 학대 경향성의 동시 및 지연효과 (The Concurrent and Lagged Effects of Parental Neglect and Abuse on Longitudinal Changes in Late Childhood School Adjustment)

  • 최수빈;유미숙
    • 한국심리학회지:학교
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    • 제16권1호
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    • pp.1-15
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    • 2019
  • 본 연구의 목적은 후기 아동기 학교적응 변화에 대한 부모 방임과 학대 경향성의 동시 및 지연효과를 확인하는 데 있다. 이를 위해 한국청소년정책연구원에서 수행한 한국아동·청소년패널조사(KYCPS)의 초1 패널 자료 중 4차년도에서 7차년도(초등학교 4학년에서 중학교 1학년)까지의 종단자료를 활용하였다. 후기 아동기 학교적응 변화에 대한 부모 방임과 학대 경향성의 동시 및 지연효과를 확인하기 위한 분석방법으로는 잠재성장모형(Latent Growth Model: LGM)을 적용하였다. 연구 결과는 다음과 같다. 첫째, 학교적응의 수준은 점차 감소하는 것으로 나타났다. 둘째, 방임과 학대는 학교적응에 대한 동시효과가 있는 것으로 나타났다. 셋째, 방임은 학교적응에 대한 지연효과가 있는 것으로 나타났으나 학대의 경우 지연효과가 나타나지 않았다. 본 연구에서는 위의 결과를 토대로 후속 연구에서 고려할 사항을 제안하였으며, 추후 방임과 학대를 경험하는 후기 아동의 학교적응을 이해하고 효과적으로 도울 수 있을 것으로 기대된다.

Late Fall Nitrogen Application and Turf Cover for Zoysiagrass (Zoysia japonica) Spring Green-up

  • Oh, Jun-Suk;Lee, Yu-Jin;Lee, Sang-Kook
    • Weed & Turfgrass Science
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    • 제4권4호
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    • pp.383-389
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    • 2015
  • The use of zoysiagrass (Zoysia japonica Steud.) in the transition zone is limited because of a lack of cold hardiness although zoysiagrass has many advantages compared to other warm-season and cool-season grasses. Late-fall N fertilization is often applied for darker green color of turfgrass in early spring and more extensive root growth without rapid top growth. The objective of the study was to evaluate the effects of late fall N application and turf cover for zoysiagrass spring green-up. Clear polyvinyl chloride (PVC) film was used for turf cover. The amount of N applied were 5 and $10g\;N\;m^{-2}$ for the low and high N rate treatments, respectively. Covered zoysiagrass had greater turfgrass color and quality in early spring than non-covered zoysiagrass. The high N rate had 0.6 to 2.3 greater turfgrass quality than the low N rate on 7 of 9 rating dates. Slow-release N as late fall fertilization is more effective for turfgrass color and quality than fast-release N in spring. Turf cover could reduce the period of yellow zoysiagrass, and the earlier time of spring green-up could be advanced by increasing turfgrass quality and growth of zoysiagrass.

No Late Effect of Ionizing Radiation on the Aging-Related Oxidative Changes in the Mouse Brain

  • Jang, Beom-Su;Kim, Seolwha;Jung, Uhee;Jo, Sung-Kee
    • 방사선산업학회지
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    • 제4권3호
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    • pp.203-207
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    • 2010
  • Radiation-induced late injury to normal tissue is a primary area of radiation biology research. The present study was undertaken to investigate whether the late effect of the ionizing radiation appears as an age-related oxidative status in the brain. Three groups of 4-month old C57BL/6 mice that were exposed to $^{137}Cs$ ${\gamma}-rays$ at a single dose (5 Gy) or fractionated doses ($1Gy{\times}5times$, or $0.2Gy{\times}25times$) at 2 months old were investigated for the oxidative status of their brains with both young (2-month) and old (24-month) mice. A significant (p<0.05) decrease in superoxide dismutase (SOD) activity was observed in old mice brains compared with that of the young mice. malondialdehyde (MDA) content was significantly (p<0.05) increased in the old mice brain. However, any significant difference in SOD activity and MDA contents of the irradiated brain was not observed compared to age-matched control group mice. SOD activity and MDA content were observed within good parameters of brain aging and there were no late effects on the age-related oxidative level in the ${\gamma}-ray$ irradiated mice brains.

Effects of extra-feed intake during late gestation on reproductive performance of sow and piglet performance during weaning stage

  • Md Mortuza Hossain;Hyung Suk Hwang;In Ho Kim
    • 농업과학연구
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    • 제51권1호
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    • pp.41-51
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    • 2024
  • This study explored the effect of increased feed intake during the late gestation on the reproductive performance of sows, and fecal score in sows and piglets. A total of 21 crossbred [Landrace × Yorkshire] multiparous sows were randomly distributed into three treatments with seven replicates per treatment. Treatments: CON, 2.4 kg/day; TRT1, 3.2 kg/day; TRT2 , 3.6 kg/day. Body weight and body condition score of sow in different stages were not altered (p > 0.05) due to extra feed in late gestation. A linearly higher (p < 0.05) difference in backfat thickness during farrowing was found in this study. Average daily feed intake was increased (p < 0.05) linearly with extra feed in this experiment. The weaning body weight of piglets was increased (p < 0.05) with extra feed in the sow. The fecal score of sows and their piglets was similar (p > 0.05) in different levels of feed intake. In conclusion, extra feed to gestation sow showed a beneficial effect on improving the weaning piglet's body weight. Although there is a small improvement in the body weight of weaning pigs of sow fed 3.6 kg feed/day in the late gestation period, it is unlikely to be profitable enough to justify the additional waste of feed.

Treatment Outcome for Nasopharyngeal Carcinoma in University Malaya Medical Centre from 2004-2008

  • Ee Phua, Vincent Chee;Loo, Wei Hoong;Yusof, Mastura Md;Ishak, Wan Zamaniah Wan;Tho, Lye Mun;Ung, Ngie Min
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권8호
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    • pp.4567-4570
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    • 2013
  • Background: Nasopharyngeal carcinoma (NPC) is the commonest radiocurable cancer in Malaysia. This study aimed to determine the treatment outcomes and late effects of radiotherapy for NPC patients treated in University Malaya Medical Centre (UMMC). Materials and Methods: All newly diagnosed patients with NPC referred for treatment to the Oncology unit at UMMC from 2004-2008 were retrospectively analyzed. Treatment outcomes were 5 years overall survival (OS), disease free survival (DFS), cause-specific survival (CSS), locoregional control (LRC) and radiotherapy-related late effects. The Kaplan-Meier method was used for survival analysis and differences in survival according to AJCC stage was compared using the log-rank test. Results: A total of 176 patients with newly diagnosed NPC were treated in UMMC during this period. Late presentation was common, with 33.5% presenting with T3-4 disease, 84.7% with N1-3 disease and 75.6% with AJCC stage 3-4 disease. Radical RT was given to 162 patients with 22.7% having RT alone and 69.3% having CCRT. The stipulated OTT was 7 weeks and 72.2% managed to complete their RT within this time period. Neoadjuvant chemotherapy was given to 14.8% while adjuvant chemotherapy was administered to 16.5%. The 5 years OS was 51.6% with a median follow up of 58 months. The 5 years OS according to stage were 81.8% for stage I, 77.9% for stage II, 47.4% for stage III and 25.9% for stage IV. The 5 years overall CSS, DFS and LRC were 54.4%, 48.4% and 70.6%, respectively. RT related late effects were documented in 80.2%. The commonest was xerostomia (66.7%). Other documented late effects were hearing deficit (17.3%), visual deficit (3.1%), neck stiffness (3.1%), dysphagia (3.4%), cranial nerve palsy (2.5%), pneumonitis (0.6%) and hypothyroidism (1.2%). Conclusions: The 5 years OS and LRC in this study are low compared to the latest studies especially those utilizing IMRT. Implementation of IMRT for NPC treatment should be strongly encouraged.