• Korea journal of population studies
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• v.24 no.2
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• pp.149-177
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• 2001

This is a study on age-crime curve in Korea. Three data was used in this study as following: First is the crime statistics as aggregated data. Second is the police record(N=3.541 offences) of the male ex-offenders(N=988) who have been released in eleven prisons in 1987 as individual data. Third is the self-reported group-interview data(N=10.198 offences) administered to the male prisoners(N=979) in ten correctional facilities including eight adult prisons, one juvenile prison and one juvenile training center as another individual data. Generally, the right-skewness of age-crime curve has been explained through the difference of crime rate between early starters and late starters. Moffitt explains that this is because of the higher participation rate of the juvenile period of adolescence-limited offenders, but Godttfredson and Hirschi explain that this is because of a similar distribution in the crime rate of both early starters and late starters. the analysis of this study shows that Godttfredson and Hirschi’s explanation on the generality of age-crime-curve distribution is correct, but this can be modified by various factors like a economic crisis. And the peak age of juvenile period is consistent with the Moffitt’s hypothesis that the peak age is contributed to the increase of crime rate of late starters, not with Godttfredson and Hirschi’s one.

• Clinical and Experimental Pediatrics
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• v.48 no.3
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• pp.298-305
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• 2005

Purpose : We performed this study to evaluate the mean serum levels of insulin-like growth factor (IGF)-I, insulin-like growth factor binding protein(IGFBP)-2 and IGFBP-3 in healthy Korean children according to age and sex. Methods : Ninety two healthy children, consisting of 42 boys and 50 girls, were classified into five groups according to age : neonate; infancy; early childhood; late childhood; and adolescence. We measured serum levels of IGF-I, IGFBP-2 and IGFBP-3 by enzyme-linked immunosorbent assay(ELISA) and analysed the serum levels according to sex and age group. Results : For boys, the mean serum levels of IGF-I(ng/mL) in neonate, infancy, early childhood, late childhood and adolescence were $41.1{\pm}3.6$, $70.9{\pm}33.7$, $103.5{\pm}97.2$, $89.8{\pm}46.5$ and $51.4{\pm}27.8$, respectively. Those of IGFBP-2(ng/mL) were $8.2{\pm}3.4$, $5.8{\pm}0.4$, $9.3{\pm}4.0$, $9.5{\pm}1.1$ and $7.0{\pm}0.5$, respectively. Those of IGFBP-3(ng/mL) were $559.2{\pm}215.2$, $1,333.3{\pm}692.5$, $2,254.6{\pm}1,513.8$, $2,447.1{\pm}1,464.2$, $1,533.6{\pm}807.4$, respectively. For girls, the mean serum levels of IGF-I(ng/mL) according to five age groups were $53.3{\pm}9.5$, $99.3{\pm}45.8$, $69.6{\pm}51.1$, $106.2{\pm}67.0$ and $145.1{\pm}127.8$, respectively. Those of IGFBP-2 (ng/mL) were $9.1{\pm}7.4$, $5.3{\pm}0.9$, $6.9{\pm}2.0$, $10.5{\pm}3.0$ and $7.9{\pm}1.3$, respectively. Those of IGFBP-3(ng/mL) were $858.2{\pm}433.4$, $1,834.8{\pm}851.3$, $1,404.3{\pm}570.2$, $2,203.5{\pm}899.4$ and $2,029.3{\pm}1,316.7$, respectively. There were significant positive correlations observed between IGF-I and IGFBP-3 levels(r=0.589, P=0.000). Conclusion : IGF-I and IGFBP-3 levels increased as children get older. The peak level of IGFBP-3 was observed in late childhood for both boys and girls, suggesting a current trend of children reaching peak growth velocity before adolescence. The IGFBP-2 level was higher in neonates compare to infancy, suggesting that IGFBP-2 is an important substance for fetal growth.

• Journal of Nutrition and Health
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• v.34 no.6
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• pp.678-687
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• 2001

This study was carried out to compare the dietary behaviors and nutrient intakes among the students(13 years of age) of middle schools between in industrial complex and in non-industrial complex. The subjects of each group were composed of 192 male and female teenagers living in Ansan city in Korea, and this study was performed by questionnaire and dietary survey. As a result, mothers' education level and monthly family income were lower in industrial complex-families(ICF) than those in non-industrial complex-families(NICF). The subjects in ICF took dinner more irregularly than did those in NICF. The subjects in ICF skipped the meals often as there was no person preparing meals'. The subjects in ICF tended to take ra-myun, cookie or bread more often as a lunch, and they considered size and price of snack more imporandy when they chose snack than those in NICF. And the subjects in ICF had lower degree of flood habits and satisfaction on their meals than those in NICF. The daily intakes of calorie, vitamin B$_2$, calcium and iron of subjects of two groups were lower than the Korean RDA, and these intakes were lower in ICF than in NICF. These findings show that dietary behaviors and nutrient intakes were poor among the students of middle schools in ICF, in part it seems to be related to the fact that the group of ICF has low family income and mothers of ICF have the jobs that are finished late or irregularly. Therefore, these results underscore the need to provide the nutritional education for the students of middle schools and their mothers in ICF with respect to the importance of optimal nutrition through sound dietary behaviors during the adolescence.

• Journal of Korean Academy of Nursing
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• v.22 no.4
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• pp.604-619
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• 1992

This study was designed to investigate the problems facecl by adolescents who have nephrotic syndrome and who have struggled with their disease over a long time. Information obtained from this study can be utilized as basic data in planning nursing care for these adolescents. The subjects in this study were 13 adolescents who were being treated in the pediatric OPD of one general hospital in Seoul. The treatment period ranged from 2 to 15 years. The tool for this study was constructed after asking patients with nephrotic syndrome about their problems using anunstructured questionalire. Problem items which were observed during nursing cared in the pediatric unit. were also inclucled. Ten problem items were constructed on the basis of Moonlcy's problem check list and two additional items related to diet and physical activity were added to the list. The results of this study can be summerized as follows : adolescents with Nephrotic Syndrome. 1) have a vague knowledge about their illness and have distorted concepts. 2) feel social isolation within their peer group because of their changed appearance, limited physical activity and special diet regimen. 3) have problesm in heterosexual relationship because of short height in boys and changes in body propotions in girls. 4) think that their personality has changed due to illness. In most cases(8) changes were in a negative direct ion but in two cases they were positive. 5) have problems with scholastic achievement due to physical weakness and school absence. 6) who are in late adolescentce are more realistic and plan for their future taking into consideration their prognosis much more so than do patients who are in early adolescence. 7) have problems in their peer relationships. 8) have limitation their enjoy ment of leisure time. 9) have some conflict with their siblings. 10) think religion is significant and it has and influence on their life.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.2967-2971
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• 2013

Background: Extraskeletal Ewing sarcoma (EES)/primitive neuroectodermal tumours (PNET) are rare soft tissue sarcomas. Prognostic factors and optimal therapy are still unconfirmed. Materials and Methods: We performed a retrospective analysis on patients to explore the clinic characteristics and prognostic factors of this rare disease. A total of 37 patients older than 15 years referred to our institute from Jan., 2002 to Jan., 2012 were reviewed. The characteristics, treatment and outcome were collected and analyzed. Results: The median age was 28 years (range 15-65); the median size of primary tumours was 8.2 cm (range 2-19). Sixteen patients (43%) had metastatic disease at the initial presentation. Wide surgical margins were achieved in 14 cases (38%). Anthracycline or platinum-based chemotherapy was performed on 29 patients (74%). Radiotherapy was delivered in 13 (35%). At a median follow-up visit of 24 months (range 2-81), the media event-free survival (EFS) and overall survival (OS) were 15.8 and 30.2 months, respectively. The 3-year EFS and OS rates were 24% and 43%, respectively. Metastases at presentation and wide surgical margins were significantly associated with OS and EFS. Tumour size was significantly associated with OS but not EFS. There were no significant differences between anthracycline and platinum based chemotherapy regarding EFS and OS. Conclusions: EES/PNET is a malignant tumour with high recurrence and frequent distant metastasis. Multimodality therapy featuring wide surgical margins, aggressive chemotherapy and adjuvant local radiotherapy is necessary for this rare disease. Platinum-based chemotherapy can be used as an adjuvant therapy.

• Journal of the Korean Society of Clothing and Textiles
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• v.1 no.1
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• pp.1-5
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• 1977

'Adolescence' is a critical period in the process of growing and aging but important in that an adolescent becomes aware of and begins to look about him or her self. Especially with girls in their late teens (15$\~$18), they pay more attention to their looks and clothes than the boys do, which affects to some extent the formation of their personality and their behavior. From this point .of view. it is significant to establish the standard size of high-school girls' clothes. This study aims to measure high-school girls in size and to establish the standard size of their clothes; furthermore. to enable them to lead a satisfactory living with more appropriate size of clothes. The results, analyzed by two different representing items which resulted in little difference, are as belows: 1) Stature had a significant correlation with posterior waist height; bust girth had the most significant correlation with weight. and also some considerable correlation with other representing items; 2) The F-test result showed significant difference on $1\%$ level over all the items between the measured (Y) and the estimated (Y); the correlation among the representing items was considerable also; 3) When the measurement increases in stature by 4cm, bust girth by 4cm. and posterior shoulder width by 2cm respectively, the increase or decrease in other items are as shown on Table 4. Since this study was carried out in girls' high-schools in Seoul, it is expected to extend its further study throughout the nation. thus contributing to comprehending the whole truth of people's body-size and promoting the fabrication and modelling of the original clothes for the nation by the strict standard size up to making ready-made clothes with no difficulty in setting the standard and model size.

• The Journal of Pediatrics of Korean Medicine
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• v.19 no.2
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• pp.197-213
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• 2005

Objective : The purpose of this study was to investigate chief complaints of pediatric outpatients .Fin the oriental hospital and search for a trend of patients and their symtoms. Method : The study was composed of 2,915 new patients aged between 0 and 20 who had been visited pediatrics in ${\bigcirc}{\bigcirc}$ university oriental hospital from 2001 to 2004. Results : The percentage of new patients decreased every year with 30.7% in 2001, 25.5% in 2002, 24.1% in 2003, 17.8% in 2004. The age distribution showed 9.9% in infancy patients, 62.6% in early childhood, 16.8% in late childhood, 10.6% in adolescence. The percentage of infants decreased every year with 13.3% in 2001, 9.4% in 2002, 8.8% in 2003, 7.1% in 2004. The percentage of adolescents increased every year with 8.0% in 2001, 9.6% in 2002, 12.8% in 2003, 13.5% in 2004. Systemic division of chief complaints was respiratory symtoms(37.6%), general symtoms(26.1%), digestive symtoms(19.2%), skin symtoms(6.8%), nervous and mental symtoms (6.1%), urinary symtoms(2.2%), musculoskeletal symtoms(1.3%) and others(0.7%) in order of frequency. The main chief complaints were nasal mucus/obstruction(17.5%), weakness(16.9%), cough(12.8%), loss of appetite(9.8%), inappropriate growth(4.3%), atopic skin problem(3.4%), repeated common cold(2.4%), abdominal pain(2.4%), vomiting (2.2%), diarrhea(2.0%) and fever (1.9%). Loss of appetite, inappropriate growth and repeated common cold increased every year. Diarrhea and convulsion decreased every year. Conclusions : The two main causes of visit of patients were respiratory problems and improvement of general condition. More data of patients should be accumulated for further study. Not only analysis according to chief complaint, but also analysis according to diagnosis will accomplish more aaccurate information about disease of childrens in the future.

• Journal of Genetic Medicine
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• v.17 no.1
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• pp.39-42
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• 2020

The Senior-Loken syndrome was first described in 1961 as an oculo-renal disease consisting of familial juvenile nephronophthisis and Leber congenital amaurosis. It is a rare autosomal recessive disorder with a prevalence of 1:1,000,000 caused by mutations in nine genes (NPHP 1-8 and NPHP 10). Ocular manifestations (e.g., photophobia, nystagmus, and extreme hyperopia) occur within the first few years of life while renal manifestations (e.g., formation of multiple cysts impairing kidney function and end-stage renal disease) appear in late childhood to adolescence. Here, we report a case of a Filipino male presenting with rotatory nystagmus and progressive deterioration of vision since childhood. He had congenital amaurosis and juvenile nephronophthisis that progressed to end stage renal disease by age 19. All laboratory and imaging findings were consistent with chronic kidney disease. Molecular genetic testing of ciliopathy-related genes was performed revealing a homozygous mutation in exon 11 of the IQCB1/NPHP5 gene, c.1090C>T (p.Arg364^⁎). This sequence change created a premature translational stop signal resulting in a truncated protein product, nephrocystin-5 and its consequent loss of function. His symptoms eventually improved with initiation dialysis. The prognosis of Senior-Loken syndrome remains dismal and a high index of suspicion, early diagnosis and timely intervention of renal complications are warranted.

• Journal of the Korea Convergence Society
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• v.10 no.5
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• pp.63-70
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• 2019

Periodontal disease as one of oral diseases is a chronic disease that continuously worsens once it occurs. It begins with gingivitis in the late school childhood. Its prevalence rate gradually increases in adolescence and continues to rise until young and middle ages. Therefore, the preventive care for the disease in one's whole life is of very importance. Since periodontal disease can be prevented and controlled by oral health behaviors, this study focuses on the relation between adults' oral health behaviors and the disease and emphasizes its importance. Based on the data of the 2015 6th (3rd Year) National Health and Nutrition Examination Survey, the prevalence rate of periodontal disease was compared according to study subjects' oral health behaviors. As a result, gum disease treatment, the count of gum brushing, use of dental floss use of interdental brush, and subjective oral health condition were statistically meaningful. Given that oral health behaviors are related to periodontal disease, it is necessary to conduct a systematic study for developing and performing the oral health education program to make the right habit of oral health behaviors.

• Journal of Yeungnam Medical Science
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• v.38 no.2
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• pp.160-164
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• 2021

Oculocutaneous albinism (OCA) is a group of rare genetically heterogeneous disorders, characterized by hypopigmentation of the eyes, skin, and hair, which result in ocular abnormalities and a risk of developing skin cancer. Currently, there is no ophthalmologic procedure or drug that prevents the clinical features of OCA. Here, we report a new type of OCA in two, unrelated Korean families with the same OCA2 mutation. Affected individuals in this study are different from those of previous reports in two aspects: an inheritance pattern and clinical presentation. All reported patients with OCA have shown an autosomal recessive inheritance pattern, while our patients showed an autosomal dominant inheritance pattern. Small amounts of pigment can be acquired with age in OCA, but there is no substantial variation from adolescence to adulthood in this regard. A case where the patient attained normal pigmentation levels has never been reported. However, our patients displayed completely normal pigmentation in their late twenties. Whole exome sequencing and in-silico analysis revealed a novel mutation, OCA2 c.2338G>A p.(G780S) (NM_000275) with a high likelihood of pathogenicity. Sanger sequencing of p.G780S identified the same mutation in the affected individuals, which was not found in the family members with normal phenotype. We hypothesize that OCA2 G780S not only acts as a pathogenic variant of OCA but also induces pigmentation by enhancing the melanogenesis gene expression of other modifier genes, such as SLC45A2 and TPC2. These findings may provide further understanding of melanin biosynthesis and new treatment methods for OCA.