• The Korean Journal of Pain
• /
• v.5 no.2
• /
• pp.249-257
• /
• 1992

It is general knowledge that knee joint pain can be attributed to trauma and degenerative change around the knee joint. However most patients who have suffered from pain or limited range of motion of the knee joint show no definite pathology on X-ray or laboratory examination. We examined 242 patients with knee joint pain and found compression or entrapment of the articular nerve fiber by the tissue around the knee joint resulted in pain in almost all cases. Conclusion: by relieving the compression of the articular nerve fiber with just physical therapy and LASER stimulation on the identified trigger points, in conjunction with NSAIDs, muscle relaxants, were found to be very effective in the treatment of knee joint pain.

• Journal of Chest Surgery
• /
• v.44 no.4
• /
• pp.311-313
• /
• 2011

Hemangiomas that arise in cervical esophagus are extremely rare, representing 3.3% of all benign esophageal tumors. Although endoscopic mucosal resection (EMR) and potassium titanyl phosphate/yttrium aluminum garnet (KTP/YAG) laser therapy have been used with success for small tumors, the safety and efficacy in the case of large tumors remains uncertain. We report the successful resection of cervical esophageal hemangioma through a cervical esophagotomy in a patient with thyroid cancer who needed a cervical collar incision.

• Archives of Craniofacial Surgery
• /
• v.9 no.1
• /
• pp.27-30
• /
• 2008

Purpose: It's difficult to treat port wine stain with nodular change in Laser therapy, and many patients with port wine stain suffer from restriction in social activity in case that port wine stain located on face. We present our experience in excision of port wine stain and skin graft in two patients who had port wine stain with nodular change on their faces. Methods: After excision of discolorized skin and nodular changed lesion of port wine stain, thick split thickness skin graft was done. Results: There was no recurred nodular hypertrophy for 3 months and 3 years of follow up periods. Conclusion: Surgical treatments of port wine stain with nodular change can lead significant improvement of lesion and social intercourse.

• The Journal of Korean Medicine
• /
• v.29 no.3
• /
• pp.161-168
• /
• 2008

We report the case of an 18-year-old woman with a 6-year history of widespread facial plane warts that had proved resistant to repeated treatments with laser therapy and imiquimod cream. The patient had recurrent lesions, which subsequently resolved with treatment. We diagnosed the case as heat and blood stasis and qi deficiency damp stagnation. Treatment with herb medication and herbal external wet dressing was initiated. During the 4-month treatment period, the warts resolved gradually. At 4 months follow up, there were no recurrent lesions and no other adverse effects.

• The Korean Journal of Pain
• /
• v.9 no.1
• /
• pp.114-119
• /
• 1996

Buerger's disease is a nonatherosclerogic occlusive inflammatory disease of medium and small arteries, and veins, of unknown cause. It occurs predominantly in young males who are habitual tabacco users. These patients often complain of painful ulcerations of their digits. The care of this disease is very difficult when the treatment is delayed. Consequently, early treatments are most important to patients with Buerger's disease. This disease can be treated with sympathetic block such as stellate ganglion block for upper extremities and lumbar epidural block, and lumbar sympathetic block for lower extremities. Intravascular regional sympathetic block can be another method of treatment. However, discontinuation of smoking is the most basic and essential treatment for Buerger's disease. We treated 43 Buerger's disease patients with stellate ganglion block and laser therapy. The treatment was not effective for three patients who definitely required amputation.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.26 no.2
• /
• pp.94-96
• /
• 2015

Several distinct pathologic entities are encompassed in benign vocal fold lesions, including intracordal cysts, vascular ectasia, as well as vocal fold nodules and vocal fold polyps. Treatment options for theses lesions include both medical/conservative and surgical techniques. First approaches should be focus on correcting the underlying causative factors, largely through voice therapy and education. There are several laryngomicrosurgery techniques for removal of benign lesions. Much debate continues regarding the relative merits of cold instruments versus carbon dioxide laser removal of benign vocal fold lesions. Both techniques have the merits and the demerits each other. Therefore the surgeon should well comprehend the merits of each techniques and choose the proper procedure for patient's lesions.

• Proceedings of the Materials Research Society of Korea Conference
• /
• 2012.05a
• /
• pp.55.1-55.1
• /
• 2012

In the first part of this talk, I will introduce an effort to use gold nanoparticles and UO22+ (uranyl) specific DNAzyme for development of highly sensitive and selective colorimetric uranyl sensors. In addition, I will discuss how DNA aptamers can be delivered by nanoparticles to cancer cell nucleus and released by ultrafast femtosecond pulsed laser for targeted cancer therapy. Finally, I will show how proteins such as streptavidin and myoglobin, or nanoparticles can be precisely aligned on DNA with nanometer resolution via backbone-modified phosphorothioate DNA and bifunctional linkers. These interesting functional and structural properties of DNA can provide new opportunities to develop dynamic DNA structures for potential use as intracellular sensors and drug delivery agents.

• Korean Journal of Bronchoesophagology
• /
• v.7 no.1
• /
• pp.54-58
• /
• 2001

Granular cell tumor or also called Abrikossoff's tumor, is a rare benign tumor that can occur anywhere in the body. Granular cell tumor may single or multiple (synchronous or metachronous). Approximately half of all granular cell tumors occur in the head and neck. most commonly in the tongue. But granular cell tumors of the larynx are rare, accounting for only 7 to 10% of all reported cases. Laryngeal tumors are usually small and men are more frequently affected than women. The exact histogenesis is still not known but most recent data support the neurogenic Schwann cell origin. The preferred treatment is local excision using cold knife or laser. Radiation therapy is of little benefit. We report a case of granular cell tumor of the larynx which was confirmed by histopathology.

• Mass Spectrometry Letters
• /
• v.10 no.3
• /
• pp.71-78
• /
• 2019

For several decades, cancer has been the primary cause of mortality worldwide. New diagnosis and regimens have been developed to improve the chemotherapeutic efficacy and the quality of life of the patients. However, cancer tissues are complex and difficult to assess. Understanding the various properties of the tumor and its environment is crucial for cancer and pharmaceutical research. Several analytical techniques have been providing new insights into cancer research. Recently, matrix-assisted laser desorption ionization (MALDI)-mass spectrometry imaging (MSI), an advanced analytical technique, has been applied to translational research. Proteomic and lipidomic profiling obtained by MALDI-MSI has been critical for biomarker discovery and for monitoring heterogenous tumor tissues. In this review, we discuss technical approaches, benefits and recent applications of MALDI-MSI as a valuable tool in cancer research, namely for diagnosis, therapy, prognosis.

• Medical Lasers
• /
• v.8 no.2
• /
• pp.80-83
• /
• 2019

Necrobiosis lipoidica (NL) is a rare, idiopathic, chronic granulomatous inflammatory disease of collagen degeneration with the risk of ulceration. Many procedures have been proposed to treat this rare disease. In this study, we applied LDM^®-MED for the management of NL, and this condition in our patient was chronic and refractory to other therapeutic options. To the best of our knowledge, no study has explored treatment of NL using ultrasound. Our results suggest that application of LDM^®-MED seems to be an effective treatment option for NL. Long-term and systematic studies are needed to determine whether such application of LDM^®-MED will be an innovative and effective treatment option for NL and various kinds of chronic wounds.