• 대한세포병리학회지
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• 제17권1호
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• pp.1-17
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• 2006

Urine cytology is the most useful technique for detecting either primary or recurrent neoplasms in the urinary tract. Although urine cytology is the traditional method of detecting these neoplasms, its diagnostic accuracy has been underevaluated because of low sensitivity. The cytologic interpretation of urinary samples is not an easy task, even with some expertise in this area, for many reasons. In low-grade urothelial carcinoma, no reliable or reproducible diagnostic cytologic criteria can be provided because of the lack of obvious cytologic features of malignancy, which is one of the main factors lowering its diagnostic accuracy. Many diagnostic markers have been developed recently to enhance its diagnostic yield, but the results have not been satisfactory. However, urine cytology plays a role in detecting high-grade urothelial carcinoma or its precursor lesions. It still shows higher specificity than any of the newly developed urine markers. Understanding the nature of urine samples and the nature of neoplasms of the urinary tract, recognizing their cytologic features fully, and using cytologic findings under appropriate conditions in conjunction with a detailed clinical history would make urine cytology a very valuable diagnostic tool.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송공학회 2012년도 하계학술대회
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• pp.471-472
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• 2012

The active shape model(ASM) is one of the most popular methods among the shape prior based segmentation methods based on its strong shape constraints using the statistic of shape information which is acquired from the training set. ASM has a few drawbacks, such as, the lack of shape variability, and the sensitivity for false locally searched points. In this paper, we suggest the patch-wise robust ASM to overcome the limitations of the ASM. In addition to the SSM, we introduce the patch-wise SSM, to reduce the shape inflexibility and to search reliable points with the point reliance measurement. The quantitative and qualitative results show the robustmness and the accuracy of the proposed method.

• Mycobiology
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• 제48권1호
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• pp.44-50
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• 2020

Calonectria pseudonaviculata and C. henricotiae are two closely related fungal species responsible for boxwood blight disease of ornamental shrubs (Buxus spp.) in the U.S. and Europe. A previous study has shown isolates of the latter species, which is restricted to Europe, to be less sensitive to tetraconazole, an azole fungicide. In this study, we have analyzed the CYP51 paralogs for polymorphism in 26 genomes, representing geographically disparate populations of C. pseudonaviculata (n = 19) and C. henricotiae (n = 7), from the U.S., Europe, Asia, and New Zealand. The presence of a CYP51A pseudogene and lack of a functional CYP51A paralog in all C. pseudonaviculata genomes examined is a novel discovery for fungi and could have implications for the evolution of resistance to antifungal chemicals.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2015년도 추계학술대회
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• pp.224-226
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• 2015

Outwardly, the people in the shipping industry are aware that multicultural working environments and conditions could have a strong influence on the operation of ships. With a lack of cultural awareness and foreign language skill of crew members on ships, there are lots of misunderstandings and miscommunications among (cross-cultural) crews. More and more maritime accidents are caused by human error in the world's oceans. Nevertheless the research on cultural diversity and human interaction on ships is still in its infancy. Due to the rapid change of the demographic make-up of crews, not only teaching and training technical skills for the crews, but also education in nontechnical skills such as cultural awareness, cultural sensitivity, intercultural competence is urgently needed. This study will deal with intercultural issues on ships. It aims to emphasize the necessity of intercultural training in MET.

• 대한치과의사협회지
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• 제51권5호
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• pp.242-249
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• 2013

The proper occlusal design is one of the most important factors for the long-term success. The purpose of this research is to investigate and define occlusal considerations to reduce failure of implant-supported fixed prostheses. The physiological movement of implants is markedly lower than that of natural teeth and they also lack in occlusal sensitivity. Proper occulsal pattern may be assigned to compensate for the biological disadvantages and occlusal contacts must be formed where the cantilever effect is minimized. Moreover, the long-term success can be assured by reducing early occulsal loading to avoid implant overloading and selecting appropriate occlusion material.

• Journal of Pharmaceutical Investigation
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• 제35권4호
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• pp.243-247
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• 2005

Although many scientists have used pectin, its feasibility in terms of tablet manufacturability with a high speed machine has never been evaluated. Therefore, compactibility of different pectin types for large scale tableting operation has been evaluated. The compactibility behavior of powder pectins was studied by a compaction simulator. It was found that pectin on its own does not produce tablets of acceptable quality even at a punch velocity as low as 20 rpm (e.g. low tensile strengths, capping and lamination irrespective of applied compression force). Thus, dwell time was introduced and more hard compact was produced as relaxation time in die increases. It was concluded that frequent structural failure observed in both pectin types was due to lack of plastic deformation, poor compactibility and high elastic recovery.

• Journal of Electrical Engineering and Technology
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• 제5권3호
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• pp.493-496
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• 2010

At present, Metal Oxide gas Sensors (MOXs) are widely used in gas detection because of its advantages, including high sensitivity and low cost. However, MOX presents well-known problems, including lack of selectivity and environment effect, which has motivated studies on different measurement strategies and signal-processing algorithms. In this paper, we present an artificial neural network (ANN) that models an MOX sensor (TGS822) used in a dynamic environment. This model takes into account dependence in relative humidity and in gas nature. Using MATLAB interface in the design phase and optimization, the proposed model is implemented as a component in an electronic simulator library and accurately expressed the nonlinear character of the response and that its dependence on temperature and relative humidity were higher than gas nature.

• Journal of Information Technology Applications and Management
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• 제24권2호
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• pp.81-96
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• 2017

Forecasting long-term mobile service demand is inevitable to establish an effective frequency management policy despite the lack of reliability of forecast results. The statistical forecasting method has limitations in analyzing how the forecasting result changes when the scenario for various drivers such as consumer usage pattern or market structure for mobile communication service is changed. In this study, we propose a dynamic model of the mobile communication service market using system dynamics technique and forecast the future demand for long-term mobile communication subscriber based on the dynamic model, and also experiment on the change pattern of subscriber demand under various scenarios.

• 비교문화연구
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• 제47권
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• pp.1-26
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• 2017

본 논문은 1990년대 이후 발표된 여화(余華)의 "재세우중호함(在細雨中呼喊)"(1993), 소동(蘇童)의 "성북지대(城北地帶)"(1994), 왕강(王剛)의 "영격역사(英格力士)"(2004)에 나타난 가족결핍과 그 서사적 대응방식을 살펴보는 것을 목적으로 삼는다. 소설에 공통적으로 등장하는 소재인 결핍된 가족은 존재의 부재를 뜻하기도 하지만 그 기능과 역할의 부재를 의미하기도 한다. 결핍을 야기하는 원인은 작품마다 서로 다르며 대응 양상 또한 차이를 보인다. 중국의 성장 서사는 오랜 시간 동안 전통의 유제와 여러 가지 정치적 압박 속에서 성장과정에서 일어나는 부모와의 갈등, 성장자 자신의 내면의 고통들을 집단의 경험 속에 매몰시켰다. 성장의 기억을 개인에게 돌려주기 시작했던 1980년대의 선취에 힘입어 1990년대 성장 서사는 지나간 연대의 강박과 피로에서 벗어난 작가들의 다양한 시도 속에서 더욱 풍부한 함의를 지니고 있다. "가랑비 속의 외침"은 친부모와 양부모에게 의도치 않은 '버려짐'을 당한 주인공의 심리적 고아의식을 보여주었고, "성북지대"는 부재된 가족에게 염증을 느끼고 또래 집단 속에서 위안을 받는 아이들의 서로 다른 성장의 이야기를 들려준다. "오, 나의 잉글리쉬 보이"는 동일시의 대상을 등장시킨다는 점에서 중국 성장소설의 주류적 서사와 구분된다. 개인의 성장은 그를 통해 진일보하고 결국 성장자 자신의 정체성을 확립하게 된다는 점에서 이 소설은 성장소설의 모범사례로 여겨진다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5427-5432
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• 2012

Background and Purpose: Ovarian cancer is the leading cause of death among gynecologic cancers because of the lack of effective early detection methods. Accuracies of the human epididymis protein 4 (HE4) and mesothelin in detecting ovarian cancer have never been systematically assessed. The current systematic review aimed to tackle this issue. Methods: MEDLINE, EMBASE, and Cochrane databases were searched (September 1995-November 2011) for studies on the diagnostic performances of HE4 and mesothelin in differentiating ovarian cancer from other benign gynecologic diseases. QUADAS items were used to evaluate the qualities of the studies. Meta-DiSc software was used to handle data from the included studies and to examine heterogeneity. All included studies for diagnostic performance were combined with sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratios (DORs) with 95% confidence intervals (CIs), summary receiver operating characteristic (SROC) curves, and areas under the SROC curves (AUC). Results: A total of 18 studies and 3,865 patients were eligible for the final analysis. The pooled sensitivity estimates for HE4 (74.4%) were significantly higher than those for mesothelin (49.3%). The pooled specificity estimates for mesothelin (94.5%) were higher than those for HE4 (85.8%). The pooled DOR estimates for HE4 (26.22) were higher than those for mesothelin (24.01). The SROC curve for HE4 showed better diagnostic accuracy than that for mesothelin. The PLR and NLR of HE4 were 6.33 (95% CI: 3.58 to 11.18) and 0.27 (95% CI: 0.21 to 0.34), respectively. The PLR and NLR for mesothelin were 11.0 (95% CI: 6.21 to 19.59) and 0.51 (95% CI: 0.42 to 0.62), respectively. The combination of the two tumor markers or their combination with CA-125 increased sensitivity and specificity to different extents. Conclusion: The diagnostic accuracy of HE4 in differentiating ovarian cancer from other benign gynecologic diseases is better than that of soluble mesothelin-related protein. Combinations of two or more tumor markers show more sensitivity and specificity.