• 제목/요약/키워드: Lack of Sensitivity

검색결과 218건 처리시간 0.025초

추계학적 지진동 모사에서 유한단층 모델의 민감도 분석 (Sensitivity Analysis of Finite Fault Model in Stochastic Ground Motion Simulations)

  • 이상현;이준기
    • 한국지진공학회논문집
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    • 제28권3호
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    • pp.159-164
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    • 2024
  • Recent earthquakes in Korea, like Gyeongju and Pohang, have highlighted the need for accurate seismic hazard assessment. The lack of substantial ground motion data necessitates stochastic simulation methods, traditionally used with a simplistic point-source assumption. However, as earthquake magnitude increases, the influence of finite faults grows, demanding the adoption of finite faults in simulations for accurate ground motion estimates. We analyzed variations in simulated ground motions with and without the finite fault method for earthquakes with magnitude (Mw) ranging from 5.0 to 7.0, comparing pseudo-spectral acceleration. We also studied how slip distribution and hypocenter location affect simulations for a virtual earthquake that mimics the Gyeongju earthquake with Mw 5.4. Our findings reveal that finite fault effects become significant at magnitudes above Mw 5.8, particularly at high frequencies. Notably, near the hypocenter, the virtual earthquake's ground motion significantly changes using a finite fault model, especially with heterogeneous slip distribution. Therefore, applying finite fault models is crucial for simulating ground motions of large earthquakes (Mw ≥ 5.8 magnitude). Moreover, for accurate simulations of actual earthquakes with complex rupture processes having strong localized slips, incorporating finite faults is essential even for more minor earthquakes.

Sensitivity analysis for finite element modeling of humeral bone and cartilage

  • Bola, Ana M.;Ramos, A.;Simoes, J.A
    • Biomaterials and Biomechanics in Bioengineering
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    • 제3권2호
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    • pp.71-84
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    • 2016
  • The finite element method is wide used in simulation in the biomechanical structures, but a lack of studies concerning finite element mesh quality in biomechanics is a reality. The present study intends to analyze the importance of the mesh quality in the finite element model results from humeral structure. A sensitivity analysis of finite element models (FEM) is presented for the humeral bone and cartilage structures. The geometry of bone and cartilage was acquired from CT scan and geometry reconstructed. The study includes 54 models from same bone geometry, with different mesh densities, constructed with tetrahedral linear elements. A finite element simulation representing the glenohumeral-joint reaction force applied on the humerus during $90^{\circ}$ abduction, with external load as the critical condition. Results from the finite element models suggest a mesh with 1.5 mm, 0.8 mm and 0.6 mm as suitable mesh sizes for cortical bone, trabecular bone and humeral cartilage, respectively. Relatively to the higher minimum principal strains are located at the proximal humerus diaphysis, and its highest value is found at the trabecular bone neck. The present study indicates the minimum mesh size in the finite element analyses in humeral structure. The cortical and trabecular bone, as well as cartilage, may not be correctly represented by meshes of the same size. The strain results presented the critical regions during the $90^{\circ}$ abduction.

학령기 아동을 위한 구강건강프로그램 적용 (Application of Dental Health Program for Elementary School Children)

  • 안혜영;이꽃메
    • Child Health Nursing Research
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    • 제16권1호
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    • pp.49-55
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    • 2010
  • Purpose: In this study an analysis was done of participants who were educated using a dental health program as compared to a control group who only used a booklet on the subject. The participants were elementary school children and the education focused on dental health knowledge, behavior, health belief, and self-efficacy. Methods: Sixth grade students from two different schools in D-city were assigned to an experimental group which was educated using a dental health program over five weeks and a control group which was educated with a dental care booklet. Results: The experimental group showed significant increases in knowledge, behavior, sensitivity, severity, benefit, belief, and self-efficacy indicating that the program was effective, but there were no significant differences in self-efficacy, sensitivity, severity, importance, or disability between the two groups. Significant differences between the groups were found for knowledge, behavior, and benefits regarding dental health. Conclusion: The results of this study indicate that a dental health program for elementary school students is effective in increasing their knowledge and behavior regarding dental health but the lack of significant differences in several of the variables in this study may be related to the education provided to the control group using a booklet.

Effects of Dietary Starch and Sucrose on Tissue Responsiveness and Sensitivity to Insulin in Goats Fed a High-concentrate Diet

  • Fujita, Tadahisa;Kajita, Masahiro;Sano, Hiroaki
    • Asian-Australasian Journal of Animal Sciences
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    • 제20권3호
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    • pp.385-392
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    • 2007
  • A glucose clamp technique was used to compare dietary starch (ST), starch plus sucrose (ST+SU) and sucrose (SU) with regard to the effect on tissue responsiveness and sensitivity to insulin in intact adult male goats. The goats were fed diets containing 1.2 times of ME and CP for maintenance requirements twice daily for 21 d. Of the energy intake, 30% was offered with ST, ST+SU or SU for the respective diets, and 70% as alfalfa hay, ground corn and ground soybean meal at the respective weight ratio of 1, 1, and 0.3 for all diets. Tissue responsiveness and sensitivity to insulin were evaluated using a hyperinsulinemic euglycemic clamp technique with four levels of insulin infusion beyond 13 h after feeding. The concentrations of plasma metabolites and insulin were also determined at 3, 6 and 13 h after feeding to evaluate the effects of different carbohydrates on metabolic states in the body. Plasma glucose concentration was higher (p = 0.01) for SU diet than for ST and ST+SU diets. Increasing SU intake decreased (p<0.01) plasma acetate concentration across the time. At 3 h but not 6 and 13 h after feeding, high lactate (p = 0.01), and non-significant high propionate (p = 0.14) and low urea nitrogen (p = 0.19) concentrations were observed in plasma on SU compared with ST and ST+SU diets. Plasma insulin concentration was not different (p = 0.44) between ST and SU fed animals. In the glucose clamp experiment, considering the effects on the maximal glucose infusion rate (tissue responsiveness to insulin, p = 0.54) and the plasma insulin concentration at half-maximal glucose infusion rate (insulin sensitivity, p = 0.54), SU was not different from ST. It is concluded that SU may not be greatly different from ST with regard to the effect on tissue responsiveness and sensitivity to insulin in adult goats when fed twice daily as part of a high-concentrate diet. The possible greater effects of SU on plasma metabolites concentrations at 3 h than at 6 and 13 h after feeding suggest that a lack of persistency of SU effects during the postfeeding period may be associated with the poor response to SU in insulin action.

추백리-가금티푸스의 혈청학적 모니터링 계획수립을 위한 표본크기 (Determination of sample size to serological surveillance plan for pullorum disease and fowl typhoid)

  • 박선일;박최규
    • 대한수의학회지
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    • 제48권4호
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    • pp.457-462
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    • 2008
  • The objective of this study was to determine appropriate sample size that simulated different assumptions for diagnostic test characteristics and true prevalences when designing serological surveillance plan for pullorum disease and fowl typhoid in domestic poultry production. The number of flocks and total number of chickens to be sampled was obtained to provide 95% confidence of detecting at least one infected flock, taking imperfect diagnostic tests into account. Due to lack of reliable data, within infected flock prevalence (WFP) was assumed to follow minimum 1%, most likely 5% and maximum 9% and true flock prevalence of 0.1%, 0.5% and 1% in order. Sensitivity were modeled using the Pert distribution: minimum 75%, most likely 80% and maximum 90% for plate agglutination test and 80%, 85%, and 90% for ELISA test. Similarly, the specificity was modeled 85%, 90%, 95% for plate agglutination test and 90%, 95%, 99% for ELISA test. In accordance with the current regulation, flock-level test characteristics calculated assuming that 30 samples are taken from per flock. The model showed that the current 112,000 annual number of testing plan which is based on random selection of flocks is far beyond the sample size estimated in this study. The sample size was further reduced with increased sensitivity and specificity of the test and decreased WFP. The effect of increasing samples per flock on total sample size to be sampled and optimal combination of sensitivity and specificity of the test for the purpose of the surveillance is discussed regarding cost.

대학병원 영양부서 운영체계 변경의 비용.편익분석 (Cost , Benefit Analysis of Operation System Change in the Hospital Foodservice)

  • 김형미;양일선;박은철;임현숙
    • 대한영양사협회학술지
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    • 제6권1호
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    • pp.33-43
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    • 2000
  • Environmental pressures from such sources an economic condition, the government and inter-institutional competition create managerial challenges. Economic pressures may be forcing dietetic dept, in hospital to utilize cost∙benefit analysis to assist them in their problem solving. Cost∙benefit analysis have been widely used in business, industry and many other fields with only limited application to foodservice. Due to the lack or this information the purposes of this study were to identify use of cost∙benefit analysis in hospital foodservice system to evaluate the economic efficiency of alternatives, and to make recommendation for operation system change. Using the cost∙benefit method, cash flows are separated into cost and benefits. For an alternative to be selected, indicators, such as NPV, benefit-cost ratio (B/C ratio) with 5% discount rate per annum. The sensitivity analysis was also conducted with difference rate 3%, 7% respectively and reduced employee payroll change. The result of this study can be summarized as follows : 1. The total cost of investment for operation system change was 390,570 thousand won and the total benefit through operation system change was 865,808 thousand won. 2. Net present value(NPV) for 5 years was 475,239 thousand won and benefit-cost ratio was 2.22. 3. In sensitivity analysis with different discount rate 3%, 7%, benefit-cost ratio was 2.25, 2.18 respectively, with total reduced employee payroll change, benefit-cost ratio was 2.86. In conclusion, total benefits were exceeded total costs. Therefore, the project of operation system change in hospital foodservice was found to be economically efficient.

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첨가제 및 패턴인식에 의한 후막 SnO2 가스센서의 선택성 향상 (The Enhancement of Selectivity in Thick Film SnO2 Gas Sensors by Additives and Pattern Recognition)

  • 정해원;김종명;박희숙;윤기현
    • 한국세라믹학회지
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    • 제40권11호
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    • pp.1073-1077
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    • 2003
  • Sn $O_2$ 가스센서는 낮은 농도의 가연성 가스 및 유독 가스를 표면 저항의 변화로부터 탐지할 수 있으나, 가스 선택성이 부족하다는 단점을 가지고 있다. 이러한 단점을 보완하기 위해서는 가스반응기구의 규명과 같은 기초이론 연구와 함께 선택성이 우수한 센서재료의 개발 및 적절한 신호처리방법의 적용이 필요하다. 본 논문에서는 Sn $O_2$ 표면에서 일어나는 에탄올 (C$_2$ $H_{5}$OH)과 아세토니트릴($CH_3$CN)의 촉매산화반응을 가스크로마토그래피 분석을 통해 확인하였다. PdCl$_2$가 첨가된 Sn $O_2$ 센서는 에탄올과 아세토니트릴에 대하여 높은 감도를 보였고, 반면에 La$_2$ $O_3$가 첨가된 Sn $O_2$ 센서는 에탄올에 대해서는 높은 감도를, 그리고 아세토니트릴에 대해서는 낮은 감도를 보였다. 이들 두 센서재료 개발 및 패턴인식기법적용을 통하여 아세토니트릴에 대한 선택성을 크게 증가시킬 수 있었다. 아세토니트릴에 대한 최소 탐지농도는, 공기 중에서는 15 ppm이었고, 다른 방해가스와 함께 존재할 경우에는 20 ppm에서 100 ppm 정도로 나타났다.

픽셀 단위 컨볼루션 네트워크를 이용한 복부 컴퓨터 단층촬영 영상 기반 골전이암 병변 검출 알고리즘 개발 (Development of Bone Metastasis Detection Algorithm on Abdominal Computed Tomography Image using Pixel Wise Fully Convolutional Network)

  • 김주영;이시영;김규리;조경원;유승민;소순원;박은경;조백환;최동일;박훈기;김인영
    • 대한의용생체공학회:의공학회지
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    • 제38권6호
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    • pp.321-329
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    • 2017
  • This paper presents a bone metastasis Detection algorithm on abdominal computed tomography images for early detection using fully convolutional neural networks. The images were taken from patients with various cancers (such as lung cancer, breast cancer, colorectal cancer, etc), and thus the locations of those lesions were varied. To overcome the lack of data, we augmented the data by adjusting the brightness of the images or flipping the images. Before the augmentation, when 70% of the whole data were used in the pre-test, we could obtain the pixel-wise sensitivity of 18.75%, the specificity of 99.97% on the average of test dataset. With the augmentation, we could obtain the sensitivity of 30.65%, the specificity of 99.96%. The increase in sensitivity shows that the augmentation was effective. In the result obtained by using the whole data, the sensitivity of 38.62%, the specificity of 99.94% and the accuracy of 99.81% in the pixel-wise. lesion-wise sensitivity is 88.89% while the false alarm per case is 0.5. The results of this study did not reach the level that could substitute for the clinician. However, it may be helpful for radiologists when it can be used as a screening tool.

Pd nanoparticles on poly(amidoamine) dendrimers modified single-walled carbon nanotubes as highly sensitive hydrogen gas sensors

  • Lee, Jun-Min;Lee, Eun-Song-Yi;Jeon, Kye-Jin;Ju, Seong-Hwa;Jung, Yeong-Ri;Kim, Sung-Jin;Lee, Woo-Young
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2009년도 춘계학술대회 논문집
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    • pp.93-93
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    • 2009
  • In order to overcome the lack of reactivity with hydrogen gas ($H_2$) and utilize unique properties of Carbon Nano Tubes (CNTs) for the application to hydrogen sensors, there have been intensive works on the surface functionalization of CNTs with various types of nanoparticles including Pd. In the present work, we have investigated the effect of dendrimers and Pd nanoparticles to the hydrogen sensing properties of CNTs by comparing three types of samples: Pd/SWNTs (Sample I), Pd/dendrimer/SWNTs (Sample II) and heat-treated Pd/dendrimers/SWNTs (Sample III). As a result of IV measurement under the $H_2$ and air, sample I was found to have a high sensitivity (25%) to $H_2$, but to have a very slow response time (324 s) and recovery rate. On the other hand, Sample II was found to show much faster response time (3 s) and good recovery rate but lower sensitivity (8.6%) than Sample I which is due to induced dipole moments in the dendrimers. Interestingly, Sample III showed both fast response time (7 s) and high sensitivity (25%), indicating that the pyrolysis of the dendrimers during heat treatment which reduce the distance between the surface of the SWNTs and the functionalized Pd nanoparticles plays a key role in improving the sensitivity. The pyrolysis of the dendrimers in Pd nanoparticle-dendrimer-SWNTs was found to enable a significant electrical conductance modulation upon exposure to extremely low concentrations (10 ppm) of $H_2$ in air. Our results demonstrate that the Pd Nanoparticle-Grafted Single-Walled Carbon Nanotubes(SWNTs) with Dendrimers can be used to detect hydrogen, makingoutstanding properties such as fast response, and recovery time, high sensitivity, low detection limit at room temperature compared with other types of hydrogen sensors.

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형광기관지경의 미래 (Future of Autofluorescence Bronchoscopy)

  • 장태원
    • 대한기관식도과학회지
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    • 제15권2호
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    • pp.30-35
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    • 2009
  • Lung cancer could be developed through a series of morphological changes from dysplasia to carcinoma in situ and then invasive cancer. However, precancerous lesions are generally a few cell layers thick and are detected only by chance. Autofluorescence bronchoscopy(AFB) is one of the newly developed diagnostic tools to detect the pre-cancerous lesions m the bronchial tissue. Several studies have shown that AFB improved the rate of detection of cancer and dysplastic lesions of the airway, especially those in intraepithelial stage. However, there were high rates of false positive with AFB, and it is also important to develop non-biopsy methods because of lack of accurate information of variable course of preneoplastic lesions regarding progression. So, many other technologies were developed, such as narrow band imaging(NBI), endobronchoscopic ultrasound, optical coherence tomography, and confocal fluorescence microendoscopy. Among the new machines, NBI is a new optical technology that can clearly visualize the microvascular structure m the mucosal layer. NBI seems to increase specificity without compromising sensitivity. In the future such techniques would make it possible to precisely study in detail the natural history of the premalignant epithelium.

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